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PubMed1987

Attitudes toward problem drinkers: cognitive, affective, and behavioral intention dimensions.

Attitudes toward problem drinkers were investigated in an experiment utilizing a 2 X 2 X 2 X 2 multivariate analysis of variance design. Subjects read one of eight case vignettes about hypothetical stimulus persons and then completed verbal report inventories to assess attitudes. All vignettes were identical except for references to the stimulus person's drinking behavior (problem or nonproblem drinking), sex, and socioeconomic status (upper-middle or low). Sex of the rater was the other independent variable in the four-way design. Problem drinking elicited a powerful halo effect such that attitudes toward persons exhibiting such behavior were found to be negative relative to normal drinkers in all attitudinal domains and across almost all variables measured. Drinking behavior may have exerted such a strong effect that the potential influence of the other variables was overpowered.

Affect↗

PubMed1989

Lick sensors as tools in behavioral and neuroscience research.

Lick sensors can be valuable tools in behavioral and neuroscience research on licking and drinking behavior. The focus of this discussion is the recording of licking in the rat. However, comments on the application of these sensors to the measuring of fluid intake are included as well. Lick sensors should be used with adequate precautions. Some constraint on the access of the animal to the drinking tube is necessary for the adequate recording of each single lick. Published drawbacks to the use of electrically operated lick sensors are discussed, and reduced to realistic proportions. With these latter sensors one can obtain behavioral and electrophysiological data that are directly related to the time of making and breaking contact of the tongue with the fluid that is drunk.

Animals↗

PubMed1975

Maternal malnutrition and the neonatal environment.

Altered behavioral development was observed in suckling rats from dams fed a low protein diet either during gestation or during the lactation period. Lactational malnutrition markedly depressed all behaviors displayed by the suckling young. These included litter fragmentation, pup climbing, rearing, feeding, and drinking behavior. Although less severe, pups from a dam fed a deficient diet during gestation displayed the same altered behavioral development. Moreover, small birth weight pups born from well-nourished dams also showed delayed behavioral development. Contact with pups was increased in dams who were malnourished during the lactation period or who were nursing pups from dams malnourished during the gestation period. Results support in part the hypothesis that malnourished early in life "functionally isolates" the developing animal from its immediate environment.

Animals↗

PubMed1995

Inhibition of nitric oxide synthase attenuates osmotic thirst in the rat.

Changes in water intake after intraperitoneal injection of a nitric oxide synthase (NOS) inhibitor was studied in the rat. Administration of NW-nitro-L arginine methyl ester (L-NAME) at a dose of 50 mg/kg attenuated osmotic thirst induced by intraperitoneal injection of hypertonic saline, but did not affect spontaneous intake of water and thirst induced by subcutaneous injection of angiotension II. Pretreatment with L-arginine significantly attenuated the inhibition of osmotic thirst evoked with subsequent L-NAME. Administration of NW-nitro-D-arginine methyl ester (D-NAME) altered neither the spontaneous nor the osmotic drinking behavior. These findings suggest that NO may affect the osmotically induced drinking.

Angiotensin II↗

PubMed1985

Drinking patterns and problems among female children and adolescents: a comparison of abstainers, past users, and current users.

The sociopsychological factors that underlie drinking behavior among 197 young girls, ages 9 through 17, are explored. Three groups-youthful abstainers, former users, and current users-were interviewed, as were their parents. These comparison groups are contrasted on 110 variables. The relative merits of four competing explanations of youthful drinking behavior-deprivation, personal deficiency, hedonistic peer culture, and family pathology-are assessed.

Adolescent↗

PubMed2004

Excessive drinking in college: behavioral outcome, not binge, as a basis for prevention.

The dichotomous variable "binge drinking" and its associated outcomes may be insufficient for understanding the drinking phenomenon on college campuses. The current study examined the behavioral outcomes associated with different drinking nights (light, typical, and heavy) in an effort to more closely examine collegiate drinking behavior. Data were collected from 236 university students, including hourly drinking rate, estimated blood alcohol concentration (BAC) was computed, and outcomes for each drinking night. Students reported drinking behavior that ranged from weekly "light night" drinking (average: 2.85 drinks, 3.34 h, end of night BAC = 0.04%) to biweekly "heavy nights" (average: 9.91 drinks, 4.93 h, end of night BAC = 0.25%). Students report encountering the greatest number of negative outcomes during heavy drinking nights, while light nights were found to have the fewest associated negative outcomes. Positive outcomes were highest on "typical" nights, although effect sizes were small. These data suggest that prevention efforts may be more successful if types of drinking night and positive outcomes become a stronger focus. Limitations and directions for future programming and research are discussed.

Adolescent↗

PubMed1975

Primate drinking system as defined by electrical stimulation of the brain (ESB).

Four rhesus monkeys were examined by ESB for drinking sites in structures that had been previously demonstrated to support drinking behavior. Three yielded a significantly greater proportion of drinking sites than expected from the earlier study, and one yielded significantly less. As the exploration proceeded, the proportion of sites yielding drinking greatly increased in the drinkers and decreased in the nondrinker, and the ratio of stimulus-bound to nonstimulus-bound drinking sites increased in the drinkers but decreased in the nondrinker. Orienting responses decreased in both drinker and nondrinker as exploration proceeded. Two sites that had reliably supported drinking in the restraint chair failed to do so when telestimulated in a free environment, but instead yielded turning, walking, and climbing behavior. The results suggest that ESB-elicited drinking is determined by stimulation of several overlapping neural systems. These probably include ascending dopaminergic and cholinergic systems which are relatively thirst specific, and a nonspecific, cholinergic component of the reticular activating system which triggers the animal to execute a prepotent response which is specific to a given animal with a given history of stimulation under particular enviromental constraints. The learning of stimulus bound drinking is proposed to have its neural locus within the system which mediates the prepotent response, rather than in a thirst system or general activation system.

Animals↗

PubMed2003

Project Match treatment participation and outcome by self-reported ethnicity.

BACKGROUND: There is a lively ongoing debate concerning the need for culturally congruent alcohol treatment, with the assumption that such treatment would meaningfully address treatment outcome disparities among ethnic minorities. Although valid on the face of it, no randomized clinical trials have yet prospectively investigated and documented whether, in fact, different ethnic groups actually fare better or worse from one another when offered mainstream, culturally "incongruent" treatment. The purpose of this study was to contrast Hispanic, black, and white client treatment engagement and outcome in an effort to identify potential health disparities related to client ethnicity. METHODS: The Project Match outpatient (N = 952) and aftercare (N = 774) samples were divided according to self-reported ethnicity: Hispanic (n = 141; 8%), black (n = 168; 10%), and white (n = 1380; 80%). Controlling for socioeconomic status using the Hollingshead Occupational scale, the three ethnic groups were contrasted on pretreatment characteristics, rates of treatment attendance, three scales of therapeutic alliance, satisfaction with treatment, and drinking outcomes for the 12 months after treatment. RESULTS: Ethnic differences in rates of therapy attendance were not robust and dissipated after controlling for socioeconomic status. No mean ethnic differences in ratings of therapeutic bonding and agreement with therapy goals were obtained, but blacks and Hispanics reported higher agreement on the value of therapeutic tasks relative to whites. Nevertheless, whites reported significantly higher global satisfaction with treatment relative to Hispanics and blacks. No ethnic main effect was found in drinking intensity during the 12-month follow-up. In contrast and only in the outpatient sample, blacks (n = 51) reported significantly higher rates of monthly abstinence relative to whites (n = 679). CONCLUSIONS: Pretreatment characteristics predictive of positive treatment outcome favored white clients relative to Hispanic and black clients, but Hispanic and black clients fared at least as well as white clients during the 12-month follow-up, at least on two measures of drinking behavior. The absence, then, of poorer drinking outcomes for the ethnic minorities suggests that they may mobilize (1). different behavior change strategies and/or (2). additional social resources to achieve comparable drinking outcomes with white clients. Specific recommendations for future research are made.

Alcoholism↗

PubMed1985

Toward an analogue of alcoholism in mice: criteria for recognition of pharmacologically motivated drinking.

Two criteria of alcoholic drinking behavior--inelasticity of demand and dissociation of intake from normal eating and drinking--are illustrated by study of alcohol-preferring C57BL/6J mice. Although these mice drink enough to become intoxicated for brief periods each night, they do not meet the more rigorous criteria for pharmacologically motivated drinking. Their intake of alcohol was dramatically decreased when they were offered diets augmented with sugar or Crisco, and the temporal pattern of drinking was correlated with the intake of food. Thus, their motivation for drinking alcohol is related to nutrition and is not drug-seeking comparable to that of human alcoholics. Since the tests are simple and decisive, it might be useful to apply them to all putative models of alcoholism.

Alcoholism↗

PubMed1998

Effects of L-arginine on angiotensin II-related water and salt intakes.

Nitric oxide (NO) has been implicated centrally as an inhibitory neuromodulator, acting in short feedback loops. Neurons capable of NO synthesis have been localized in various thirst-related hypothalamic nuclei. Intracerebroventricular (icv) injection of L-arginine (L-arg), the precursor for NO, has previously been shown to attenuate both dehydration- and angiotensin II (Ang II)-induced drinking behavior. The present study further examines the effects of L-arg on drinking. We confirmed that icv administration of L-arg (50 microg) reduced water intakes induced by both 24 h water deprivation and icv Ang II (250 ng). We additionally showed that L-arg inhibited the water intake induced by peripheral injection of Ang II and the intake of 0.3 M NaCl following 24 h sodium depletion. We demonstrated the behavioral specificity of L-arg treatment by showing that it did not inhibit the intake of sucrose in food deprived rats and did not act as an unconditional stimulus for the formation of a conditioned taste aversion. These results lend further support to the idea that NO plays a role in modulating fluid balance and drinking behavior.

Angiotensin II↗

PubMed2006

Binge drinking and health behavior in medical students.

OBJECTIVES: The objective of this study was to assess the prevalence of binge drinking and its relation to other health behaviors, drinking-related attitudes and perceived social norms among German medical students. METHODS: 271 first-year German medical students completed a cross-sectional, self-administered survey. A total of 252 (62% female and 38% male) students provided useable surveys. The mean age was 20.6years (S.D.=1.7). RESULTS: Most students reported heavy drinking with 24% having one episode in the past 2 weeks (Infrequent Bingers) and 28% having two or more episodes (Frequent Bingers). Men were more likely than women to have had a binge drinking episode. Frequent binge drinkers saw more pros of drinking and reported a higher temptation to drink than students in the other groups. Additionally, they were more likely to smoke, use cannabis, not exercise and not eat fruits and vegetables. All students overestimated their peers' alcohol intake and binge drinking frequency. CONCLUSIONS: Binge drinking was highly prevalent in this sample and clearly related to other health risk behaviors. Drinking rates were similar to college students in other Western countries. Future research needs to assess the consequences of this multiple risk behavior among medical students regarding academic and professional performance as well as personal health.

Adult↗

PubMedDate not supplied

Examination of the short form of the Inventory of Drinking Situations (IDS-42) in a young adult university student sample.

The 42-item version of the Inventory of Drinking Situations (IDS-42) assesses relative frequency of drinking behavior across eight categories of drinking situations and was originally developed as a method for identifying high-risk situations in alcoholic samples. This study was designed to examine the psychometric properties of the IDS-42 in a sample of university students in order to assess its suitability as an assessment tool in the non-clinical population. Three hundred and ninety-six students (111 M, 283 F, 2 with missing gender data) completed the IDS-42 and a well established measure of drinking motives, the Drinking Motives Questionnaire (DMQ). Confirmatory factor analysis of the IDS-42 established a hierarchical factor structure with eight lower-order factors and three higher-order factors of negatively-reinforcing situations, positively-reinforcing situations, and temptation situations. The eight lower-order IDS-42 factors demonstrated moderate to high internal consistency and excellent concurrent validity with conceptually-similar DMQ subscale scores. Non-parametric analyses revealed that male students reported a higher drinking frequency overall as compared to female students, particularly in IDS-42 situations involving Social Pressure to Drink, Pleasant Times with Others, Testing Personal Control, and Urges and Temptations. Across the entire sample of university student drinkers, a higher drinking frequency was reported in positively-reinforcing situations as compared to negatively-reinforcing situations and temptation situations, as predicted. Results suggest the IDS-42 possesses good psychometric properties and support its utility as a tool in identifying situation-specific antecedents to drinking among university students.

Adolescent↗

PubMedDate not supplied

A comparison of problems-of-life for blacks and whites entering substance abuse treatment programs.

Blacks in the general population experience alcohol-related health problems to a greater extent than Whites, even though surveys of drinking behavior find that Blacks generally drink no more than Whites and, in fact, at younger ages Blacks actually drink less than Whites. In this study, Blacks and Whites entering randomly selected state-supported substance abuse treatment programs within a given period of time were interviewed and administered a battery of assessment instruments; results are derived from the Addiction Severity Index. A major research question was whether the higher rates of alcohol-related problems for Blacks in the general population were matched by greater severity of life-problems for Blacks in a clinical treatment population. Blacks had more severe problems than Whites in two problem areas: employment support and other drug use. Results point to socioeconomic factors as well as combined alcohol and other drug use as potential contributors to the greater alcohol-related health problems for Blacks in the general population. Comprehensive study of alcohol and other drug use norms and customs within the Black community is recommended to aid in the development of prevention and treatment strategies for alcohol-related problems among Blacks.

Adolescent↗

PubMed1986

Effect of television programming and advertising on alcohol consumption in normal drinkers.

The drinking behavior of 96 male normal drinking college students was assessed after they viewed a videotape of a popular prime-time television program complete with advertisements. Different versions of the videotape were used to evaluate the effects of a television program with and without alcohol scenes as crossed with the effects of three different types of advertisements (i.e., beer, nonalcoholic beverages and food). After viewing the videotape, the subjects, who were led to believe that they were participating in two separate and unrelated sets of experimental procedures, were asked to perform a taste rating of light beers, which actually provided an unobtrusive measure of their alcohol consumption. The results provided no support for the widely held assumption that drinking scenes in television programs or televised advertisements for alcoholic beverages precipitate increased drinking by viewers. This finding, however, must be considered in the context of the laboratory setting of the study, and thus may not generalize to real-life television viewing. Further research in this area is clearly needed, including an evaluation of the effects of television program content and advertisements on other populations (e.g., alcohol abusers).

Adult↗

PubMed2005

Alcohol expectancies in relation to personality and aggression among juvenile delinquents in Northern Russia.

The relationships between alcohol expectancies, level of alcohol use, alcohol-related problems, aggression, and personality factors in 198 Russian male juvenile delinquents were assessed. A clustering procedure was used in order to establish main patterns of alcohol expectancies, yielding three major clusters. Level of alcohol use, alcohol-related problems, aggression, and personality factors were compared across the identified clusters. It was established that juvenile delinquents with a high level of positive alcohol expectancies and aggression represented a risk-group for higher involvement in drinking behavior as well as problem drinking, which in turn are related to specific personality traits. Implications of these findings for alcohol prevention among the youth are discussed.

Adolescent↗

PubMed1999

Cognitive-behavioral coping-skills therapy for alcohol dependence. Current status and future directions.

Cognitive-behavioral coping-skills training (CBST) is an alcoholism treatment approach aimed at improving the patients' cognitive and behavioral skills for changing their drinking behavior. CBST encompasses a variety of approaches that despite their core similarities differ in duration, modality, content, and treatment setting. Numerous studies and reviews have ranked CBST among the most effective approaches for treating alcoholic patients. Nevertheless, a recent analysis of nine studies failed to identify specific CBST components that could account for the treatment's effectiveness. Furthermore, a similar analysis of 26 studies suggested that CBST's superior effectiveness was limited to specific treatment contexts (i.e., when delivered as part of a comprehensive treatment program) and to specific patient subgroups (e.g., patients with less severe alcohol dependence). Several measures may help broaden CBST's focus and effectiveness, such as incorporating components of other treatment approaches.

Adaptation, Psychological↗

PubMed1992

Alcohol expectancies, social and environmental cues as determinants of drinking and perceived reinforcement.

Increasing evidence suggests that outcome expectancies and environmental cues interact to influence post-drinking behaviors. Using an experimental methodology in a simulated social drinking setting, this research tested the potential influence of expectations for the effects of drinking, environmental cues, and beverage content on ad lib consumption and post-drinking self-perception. Eighty-eight moderate to heavy-drinking males were randomly assigned to one of eight experimental conditions in which beverage content (alcohol or placebo), social environment (friendly or unfriendly), and physical environment (simulated bar or residence) were varied. Subjects were further divided into high and low groups on three outcome expectancy factors. Unaffected by environmental cues, beverage self-administration increased when subjects strongly expected behavioral impairment from drinking but received placebo beverage. Post-drinking reports of disinhibition increased in response to friendly social cues but were not affected by beverage content or amount. Results therefore suggest that individual's beliefs about the effects of drinking influence the amounts of beverage they consume, whereas social cues more greatly affect post-drinking self-perception.

Adult↗

PubMed1975

Comparison of the effects of intracranial injections of 6-OHDA and guanethidine on consummatory behavior and monoamine depletion.

6-Hydroxydopamine (6-OHDA) has been used extensively to study the effects of catecholamine depletion on feeding and drinking behavior. The results from these experiments are variable and do not clarify the involvement of catecholamines in these behaviors. Guanethidine, which has been used in studies of the peripheral autonomic nervous system, provides an alternative method of catecholamine depletion. In the experiments reviewed here the effects of injections of 6-OHDA and guanethidine into the rat brain on consummatory behavior and temperature regulation have been compared and related to changes in monoamine levels as shown by fluorescence histochemistry. Injections of 6-OHDA into anterior hypothalamic areas have lethal effects on food deprived animals. This effect may be explained in terms of loss of ability to regulate temperature. Animals whose catecholamines were depleted by guanethidine injections into anterior lateral hypothalamus showed a consistent reduction in food and water intake and an elevation of body temperature. Reconciliation of these findings appears difficult. However, a comparative study of the intracranial diffusion patterns of guanethidine and 6-OHDA has revealed marked differences in the extent of diffusion as seen with the fluorescence histochemical method when injected acutely or chronically into the lateral hypothalamus, the substantia nigra or the amygdala of the rat brain. Cannulation damage extended up to 1 mm in diameter. Generalized damage was far greater for 6-OHDA (2 mm) than for guanethidine (0.3 mm). At the doses used guanethidine, but not 6-OHDA caused specific damage to catecholamine-containing neurons up to a distance of at least 3 mm from the cannula tip. Guanethidine was less selective for dopaminergic compared to noradrenergic neurons. These differences between the effects of the two drugs are explained in terms of their unique pharmacological properties and their estimated decay in CNS tissue. An attempt has been made to account for the differences in behavioral data and in particular the variability of the 6-OHDA data in terms of the differences in the type of damage produced by the two drugs and the extent of their diffusion. It is also argued that the different patterns of damage would not easily be distinguished by biochemical analysis, and further, that changes in injection volume and concentration may lead to different damage patterns.

Amygdala↗