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PubMed1983

Endocrine findings in rabbits after sterilization with electrocoagulation.

CO2 pelviscopy or laparotomy was performed on 370 New Zealand white rabbits and followed by coagulation of the distal uterine horns with unipolar or bipolar coagulation, endocoagulation or CO2 laser coagulation. After 1, 2, 4, 8 or 12 weeks, laparotomy was done. After a macroscopic description was done, photographic documentation and measurement of the destroyed area were done, and the uterine horns were excised. In addition to the normal histologic and electron microscope evaluation, 5 microns-thick cryostat sections were screened for the presence of nine enzymes. Progesterone levels were determined in 47 rabbits before and after stimulation with 50 IU HCG administered intravenously. As we reported at the Tenth Meeting of the American Association of Gynecologic Laparoscopists in 1981, we found a definite correlation between the type of coagulation technique and the extent of the destruction. The average progesterone levels of the animals coagulated with the monopolar high-frequency technique were significantly lower than in the endocoagulation, bipolar coagulation and control groups.

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