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[Housing quality in cities from the tenant's point of view].

Since the demand for higher quality of live has been the big discussion, also the call for a more livable city has become more and more frequent. For urban development policy it is necessary to workout conceptionally the different demands for a higher living quality. First it is essential to define the content of the term Quality of Live. In this article one tries to show how the term is broken-up in it's components and how it can be empirically tested with help of indicators. Results from different studies show what the needs of the inhabitants are and how much weight the different quality components have for different population groups. The results show that in all groups of inhabitants-aside from the superior features of a city (infrastructure)-the component living environment plays an important role. If it is rated in a negative sense, it is often the ground of leaving the city-especially for families.

Environment Design↗

[Humanizing the work place - concepts of work psychology].

Recent research on central life interests shows that the position of work within the hierarchy of values is actually changing. One of the reasons is the increasing gap between school and vocational education on one hand and the level of qualification of many work activities on the other hand. Work psychology concepts of humanization of work intend to overcome this gap by different forms of autonomy oriented work organization. Therefore it is necessary to add to the traditional criteria of evaluation and measures of work organization the criteria of personality development. This implicates on one side the deduction of the author's principles of differential and dynamic work organization from this criteria, on the other side it requests the distinction between corrective, preventive and prospective strategies of work organization. In addition, trends of autonomy oriented work organization are thought to consider also the options of decentralization and delegation of decision which have been made possible by recent developments in technology, at the same time as they can include stress-reducing and personality developing elements.

Environment Design↗

[Pollution of room air].

In the last decade the significance of indoor air pollution to human health has increased because of improved thermal insulation of buildings to save energy: air turnover is reduced and air quality is impaired. The most frequent air pollutants are tobacco smoke, radioactive radon gas emanating from the soil, formaldehyde from furniture and insulation material, nitrogen oxides from gas stoves, as well as solvents from cleaning agents. The most important pollutants leading to health hazards are tobacco smoke and air pollutants which are emitted continuously from building materials and furniture. Such pollutants have to be eliminated by reducing the emission rate. A fresh air supply is necessary to reduce the pollutants resulting from the inhabitants and their activities, the amount depending on the number of inhabitants and the usage of the room. The carbon dioxide level should not exceed 1500 ppm.

Air Pollution↗

Cost-benefit analysis as a tool for decision making in environmental projects. Application to a reduction of dioxin emissions in Tarragona Province, Spain.

BACKGROUND, AIM AND SCOPE: The Damage-Function method is an efficient tool recently used in decision-making processes concerning environmental management. It is based on finding the relation between the origin of an environmental charge, and its impact on human health and the environment. The aim of the present investigation was to assess the positive impacts, also called benefits, of changes in environmental quality, and the economic viability of an industrial project on reduction of PCDD/F emissions. It has been developed with monetary criteria of two worldwide ambits: USA and European-Union countries. METHODS: The current study is a continuation of a previous investigation in which Substance Flow Analysis and Control Analysis Techniques were used to identify and to analyze all main flow values of PCDD/Fs inside the system of Tarragona Province (Spain). In the present study, Cost-Benefit Analysis (CBA) has been employed. The benefits derived from a minimization in the incidence of cancer due to a reduction in the emission of PCDD/Fs have been evaluated considering the value of a statistically saved life (VSL). Statistical analysis about uncertainty has also been incorporated. Here, the Monte Carlo simulation technique has been used. RESULTS: It is shown that CBS results depend firstly on the kind of VSL used. In fact, the differences between the decisions as a result of applying monetary criteria in USA and EU can be explained by differences between VSL values. CONCLUSION AND RECOMMENDATION: It is concluded that, for prices estimated in Euros, the emission cleaning project in the industrial plant is not feasible under any circumstance. However, although CBA seems to be a good analytical method, the final decision corresponds to the managers, who must weigh up not only the monetary criteria, but factors such as social questions.

Benzofurans↗

(M)VOC and composting facilities. Part 1: (M)VOC emissions from municipal biowaste and plant refuse.

GOAL, SCOPE AND BACKGROUND: Malodorous volatiles derived from the decomposition of biowaste within the process of composting might pose a risk to human health. Different techniques of process engineering have been developed to minimise the burden of malodorous compounds in air possibly affecting compost workers and residents in the vicinity. METHODS: In the present study, three different composting facilities were examined for the emission of volatiles to estimate the impact of process engineering on the dispersal of odorous compounds and to discuss its relevance for human health. RESULTS AND DISCUSSION: Concentrations of single compounds belonging to alcohols, ketones, furanes, sulfur-containing compounds and especially terpenes ranged from 10(2) up to nearly 10(6) ng/m3 depending on the sampling sites and the process engineering. The ratio of MVOC and total VOC measured changed throughout the process of biodegradation. A certain combination of volatile compounds coincided with the occurrence of typical compost odour. CONCLUSION: The type of process engineering seemed to have a major impact on the emission of volatiles, as amounts of (microbial) volatiles emitted were characteristic for the different techniques used. Thus, the MVOC emission basically depends on the degree of biodegradation. It is likely that the concentrations workers are exposed to can have an impact on human health. RECOMMENDATIONS AND OUTLOOK: It is obvious that less sophisticated types of process engineering give rise to greater amounts of bioaerosols and volatiles and, therefore, technical devices have to be improved and controlled regularly to minimise adverse health effects on workers.

Bioreactors↗

Effects of a fall prevention program including exercise on mobility and falls in frail older people living in residential care facilities.

BACKGROUND AND AIMS: Impaired mobility is one of the strongest predictors for falls in older people. We hypothesized that exercise as part of a fall prevention program would have positive effects, both short- and long-term, on gait, balance and strength in older people at high risk of falling and with varying levels of cognition, residing in residential care facilities. A secondary hypothesis was that these effects would be associated with a reduced risk of falling. METHODS: 187 out of all residents living in 9 facilities, > or =65 years of age were at high risk of falling. The facilities were cluster-randomized to fall intervention or usual care. The intervention program comprised: education, environment, individually designed exercise, drug review, post-fall assessments, aids, and hip protectors. Data were adjusted for baseline performance and clustering. RESULTS: At 11 weeks, positive intervention effects were found on independent ambulation (FAC, p=0.026), maximum gait speed (p=0.002), and step height (> or =10 cm, p<0.001), but not significantly on the Berg Balance Scale. At 9 months (long-term outcome), 3 intervention and 15 control residents had lost the ability to walk (p=0.001). Independent ambulation and maximum gait speed were maintained in the intervention group but deteriorated in the control group (p=0.001). Residents with both higher and lower cognition benefited in most outcome measures. No association was found between improved mobility and reduced risk of falling. CONCLUSIONS: Exercise, as part of a fall prevention program, appears to preserve the ability to walk, maintain gait speed, ambulate independently, and improve step height. Benefits were found in residents with both lower and higher cognitive impairment, but were not found to be associated with a reduced risk of falling.

Accidental Falls↗

Guidelines for clinical applications of spatio-temporal gait analysis in older adults.

Quantifying spatio-temporal gait parameters in stationary and ambulatory geriatric settings may aid the early identification of potential fallers, as well as the documentation of illness-specific gait disorders and intervention-related changes in rehabilitative medicine. Bringing gait analysis out of the laboratory and into a clinical setting is the goal of the European GAITRite network group, initiated in 2003 in Geneva. To enhance reproducibility of gait measures and for better comparability of outcomes in clinical environments, a consensus on data collection was formulated and presented at the 2nd European GAITRite Meeting in Marseilles. The guidelines presented here are intended to facilitate network collaborations and to provide guidance to clinicians who wish to implement spatio-temporal gait analysis in clinical settings.

Accidental Falls↗

Management of problematic behavioral symptoms associated with dementia: a cognitive developmental approach.

The purpose of this 3-year study was to test the efficacy of using a theoretical model based on Piaget's cognitive developmental stages for consistent behavioral and environmental interventions for persons at all stages of Alzheimer's disease and related disorders (ADRD) in nursing home and special care units. The specific aims were to reduce problematic behavioral symptoms and the number, amount and frequency of use of psychotropic medications. After 18 months, problem behaviors and some types of psychotropic medications significantly decreased in the treatment group but not in the control group. Results of the study indicate that using behavioral and environmental interventions based on Piaget levels of cognitive development may be an effective method of managing problematic behavioral symptoms and decreasing the use of psychotropic medications in institutionalized ADRD patients.

Aged↗

Pharmacogenetics and the future of medical practice.

Pharmacogenetics is today widely proclaimed to be about to revolutionize the face of medicine. In a more realistic assessment, the implementation of molecular genetics and biology will continue to provide us, as it has done already, with better ways to diagnose and treat illnesses, but it will do so at a stepwise and evolutionary pace, based on an improved understanding of the nature of disease, allowing more specific treatments, better risk prediction, and the implementation of preventive strategies. As such, future progress in biomedicine will travel the same well-trodden paths of improved differential diagnosis and risk prediction along which it has advanced in the past decades and centuries. Thus, while meaningful biomedical research today by and large depends on the use of the newly developed tools of genetics and genomics and the insights that we gain through them, it is unlikely fundamentally to change the direction of medical progress.

Clinical Medicine↗

The human cost of fracture.

In this population-based, observational study, we document the personal burden of fracture and utilization of community and health services for women during the 12-month period following a fracture. Participants were 598 women (aged 35-92 years) with incident fracture in the years 1994-1996 who were enrolled in the Geelong Osteoporosis Study. Almost all hip fracture cases and 27% of nonhip fracture cases were hospitalized. Homes were modified in 14% of cases, and 32% of the women purchased or hired equipment to assist with activities of daily living. Three-quarters of women with hip, pelvis, or lower limb fractures were confined to the home, had to walk with a walking aid, or could walk only short distances for several weeks. After a year, nearly one-half had not regained prefracture mobility. One-seventh of women with upper-limb fractures did not venture outside the home for at least 6 weeks. Nearly half of all fracture cases needed help with personal care and housework during the first 6 weeks. After 6 months, 3.4% of all patients and 19.6% of hip, 12.8% of humeral, and 4.7% of spine fracture patients required assistance with bathing and showering. After a year, more than half of the hip fracture cases remained restricted regarding housework, gardening, and transport. These findings have important implications for rehabilitation therapy. A fracture, regardless of site, had a major impact on a woman's lifestyle and well-being. Most women were restricted in their activities of daily living and suffered loss of confidence and independence. Short-term morbidity was common for all fractures, with varying degrees of prolonged morbidity often extending to at least a year postfracture.

Absenteeism↗

Blockade of serotonin 5-HT1B and 5-HT2A receptors suppresses the induction of locomotor activity by 5-HT reuptake inhibitors, citalopram and fluvoxamine, in NMRI mice exposed to a novel environment: a comparison to other 5-HT receptor subtypes.

RATIONALE: Though 5-HT plays an important role in the modulation of motor function, which is perturbed in depressive states, little is known concerning the influence of serotonin reuptake inhibitors (SSRIs) on locomotor activity (LA). Recently, we demonstrated that SSRIs, such as citalopram, enhance LA in mice exposed to a novel environment. OBJECTIVES: This study examined the role of multiple classes of 5-HT receptor in citalopram-induced LA. METHODS: The most selective antagonists currently available were used. RESULTS: Citalopram-induced LA was dose-dependently attenuated by the 5-HT1B/1D receptor antagonists, S18127, GR125,743 and GR127,935, and by the selective 5-HT1B antagonist, SB224,289, but unaffected by the selective 5-HT1A antagonist, WAY100,635. The selective antagonists at 5-HT2A receptors, MDL100,907 and SR46,349 also dose-dependently attenuated induction of locomotion by citalopram, whereas the 5-HT2B antagonist, SB204,741, and the 5-HT2B/2C antagonist, SB206,553 were ineffective. Further, the selective 5-HT2C antagonist, SB242,084, potentiated the response to citalopram. Selective antagonists at 5-HT3 (ondansetron), 5-HT4 (GR125,487), 5-HT6 (SB271,046) and 5-HT7 (SB269,970) receptors did not significantly modify the action of citalopram. Underpinning these findings, SB224,289, GR125,743, MDL100,907 and SR46,349 likewise attenuated induction of locomotion by a further SSRI, fluvoxamine. CONCLUSIONS: The locomotor response to SSRIs of mice exposed to a novel environment is mediated via 5-HT1B and 5-HT2A receptors. In view of the importance of motor function to the etiology and treatment of depression, the significance of these observations to the clinical actions of SSRIs will be of interest to elucidate.

Animals↗

Impact of fencing on the recovery of the ground flora on heavily eroded slopes of a deciduous forest.

This paper seeks to outline early stages in the recovery of forest ground flora on eroded slopes impacted by recreation activities and to suggest how these data might be applied in the formulation of management policies for forest recreation areas. Based on a fencing experiment in the Sonian Forest near Brussels, we investigated whether, over a 6-year period, the vegetation was able to recover after having been destroyed by recreation use. Short-term trends in overall species composition were already observable during this 6-year study. Species recovery on eroded hills was related to slope, aspect, and soil type. During the considered time scale, the proportion of hemicryptophytes and the number of ancient forest species increased significantly. A downward trend was detected for Ellenberg's nitrogen and temperature indexes and for the proportion of therophytes and pioneer plants of disturbed places. Changes in species' frequencies suggest six recovery strategies: early, late, expanding, disappearing, transient, and fluctuating species. Aside from seedling reproduction from overstory influences, Luzula sylvatica appeared to be the most resilient of the species identified in the study since this species has the highest global frequency in our sampling plots and has increased its cover during the study period. Study results indicate that (1) protection from recreation has initiated the recovery of species in the herb layer, but (2) it may take a long time before vegetation previously present in the ground flora may recover in both density and species composition.

Conservation of Natural Resources↗

Soft systems methodology and the ecosystem approach: a system study of the Cooum River and environs in Chennai, India.

This paper discusses the integration of soft systems methodology (SSM) within an ecosystem approach in research to support rehabilitation and management of the Cooum River and environs in Chennai, India. The Cooum is an extremely polluted urban stream. Its management is complicated by high rates of population growth, poverty, uncontrolled urban development, jurisdictional conflicts, institutional culture, flat topography, tidal action, blockage of the river mouth, and monsoon flooding. The situation is characterized by basic uncertainty about main processes and activities, and the nature of relationships among actors and elements in the system.SSM is an approach for dealing with messy or ill-structured problematic situations involving human activity. In this work SSM contributed techniques (such as "rich picture" and "CATWOE" tools) to description of the Cooum situation as a socioecological system and informed the approach itself at a theoretical level. Application of three general phases in SSM is discussed in the context of the Cooum River research: (1) problem definition and exploration of the problem situation, (2) development of conceptual models of relevant systems, and (3) the use of these to generate insight and stimulate debate about desirable and feasible change. Its use here gives weight to the statement by others that SSM would be a particularly appropriate methodology to operate the ecosystem approach. As well as informing efforts at management of the Cooum system, this work led the way to explore an adaptive ecosystem approach more broadly to management of the urban environment for human health in Chennai.

Conservation of Natural Resources↗

Sediment flux to the sea as influenced by changing human activities and precipitation: example of the Yellow River, China.

Since the 1970s, the sediment flux of the Yellow River to the sea has shown a marked tendency to decrease, which is unfavorable for wetland protection and oil extraction in the Yellow River delta. Thus, an effort has been made to elucidate the relation between the sediment flux to the sea and the drainage basin factors including climate and human activities. The results show that the sediment flux to the sea responds to the changed precipitation in different ways for different runoff and sediment source areas in the drainage basin. If other factors are assumed to be constant, when the annual precipitation in the area between Longmen and Sanmenxia decreases by 10 mm, the sediment flux to the sea will decrease by 27.5 million t/yr; when the precipitation in the area between Hekouzhen and Longmen decreases by 10 mm, the sediment flux to the sea will decrease by 14.3 million t/yr; when the precipitation in the area above Lanzhou decreases by 10 mm, the sediment flux to the sea will decrease by 17.4 million t/yr. A multiple regression equation has been established between the sediment flux to the sea and the influencing factors, such as the area of land terracing and tree and grass planting, the area of the land created by the sediment trapped by check dams, the annual precipitation, and the annual quantity of water diversion by man. The equation may be used to estimate the change in the sediment flux to the sea when the influencing variables are further changed, to provide useful knowledge for the environmental planning of the Yellow River drainage basin and its delta.

Agriculture↗

A geomorphic explanation for a meander cutoff following channel relocation of a coarse-bedded river.

The Veteran's Fishing section of the Blackledge River in central Connecticut was relocated in the late 1950s. The relocation resulted in an unstable channel despite extensive efforts to prevent erosion. Overbank erosion and meander cutoffs were investigated using detailed survey data, characterizations of sediment deposits, flow modeling, and a moment-stability analysis. Limited reworking of revetment boulders indicate that riprap bank material was immobile during a 1979 flood event responsible for the formation of the cutoff channel. A moment-stability analysis factor-of-safety value of 1.1 supports the conclusion that riprap was not directly eroded from the banks. Alluvial particles with d(95) values ranging up to 120 mm were deposited along a bar downstream from the cutoff channel at flows estimated to be below a 1.5-year recurrence interval flow. Development of the bar deposit resulted in locally elevated water surfaces at high flow. The resulting overbank flow across the meander neck to the adjacent downstream bend led to the creation of an upstream migrating knickpoint, the erosion of approximately 16,000-year-old sediments, and the subsequent meander cutoff. The results of the study indicate that traditional erosion-control measures cannot prevent extreme channel adjustments if the geomorphic processes that control sediment continuity also are not considered.

Connecticut↗