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At least 829 records · Page 46Linked to original sources
PubMed1994

Neuropsychological toxicology of methylene diphenyl diisocyanate: a report of five cases.

The neuropsychological functioning of five men suffering alleged physical, cognitive and behavioural changes following exposure to methylene diphenyl diisocyanate (MDI), an industrial chemical, was investigated in the present study. At the time of assessment, four of the five patients remained symptomatic despite having no contact with MDI for periods ranging from 5 to 9 months. All patients reported experiencing subjective symptoms consisting of respiratory distress, headaches, depression, irritability, forgetfulness, decreased calculating ability, word-finding problems and reduced concentration. While the pattern of neuropsychological deficits varied among the patients, common findings for the group included intact psychomotor, psychosensory, visuographic and language functions accompanied by deceased concentration, mental efficiency, rate of information processing, learning ability and abstract reasoning. All five patients also revealed significant emotional distress on an objective personality measure. In general, the neuropsychological test data support the presence of behavioural and cognitive correlates of CNS injury following exposure to MDI.

Adult↗
PubMed1988

Hispanic youth, substance abuse, and stress: implications for prevention research.

Hispanic adolescents are the fastest growing ethnic-minority age group in America. They are also at high risk for drug, alcohol, and tobacco use. In this paper, the authors discuss the etiology of Hispanic adolescents' substance abuse, as explained in part by psychological stress. Based on the authors' research and on other data, a model for preventing substance abuse among Hispanic youths is presented. The model draws from coping, acculturation, social learning, and informal network theories. Concluding with a research agenda, the paper calls for descriptive, correlative, and intervention outcome studies to scientifically understand and prevent substance use among Hispanic adolescents.

Acculturation↗
PubMedDate not supplied

Lessons learned from an Internet GP information system.

We describe the prototype of an application that in actual use would allow GPs to find out more information about consultants at hospitals. This would aid the GP in making the decision about which consultant a patient should be referred to. The requirements of the application from the GP's perspective are described, together with some of the issues that have to be resolved before hospitals can provide the necessary information in a standard format. The application is implemented as a client--server system using standard Internet technologies such as Java and HTML. This architecture has a number of advantages but also revealed some issues concerning security and the format of data, among other things. The project showed that there is a desire for such a system and that that desire can be fulfilled at a relatively low cost.

Family Practice↗
PubMed1993

Short-term memory and sentence processing: evidence from neuropsychology.

Traditional models of memory assume that short-term memory, as measured by memory span, plays an important role in linguistic processing and the learning of verbal information. Contradicting this view are findings from a brain-damaged patient, E.A., who, despite a verbal memory span of about two items, demonstrated normal sentence comprehension in a variety of tasks. She was, however, impaired whenever verbatim phonological information had to be maintained or learned. These results and those from other patients with reduced span suggest that the phonological storage capacity that is critical to memory span plays only a limited role in language processing, specifically in the maintenance and learning of phonological forms. Implications for models of short-term memory are discussed. It is argued that short-term memory should be seen as deriving from the processing and retentive capacities of language processing modules, with span tasks drawing on only a subset of these modules.

Attention↗
PubMed1999

Orientation invariance in naming rotated objects: individual differences and repetition priming.

In naming drawings of complex common objects, unpracticed naming times increase with rotation away from the upright, but this orientation effect is attenuated with practice. In principle, attenuation could result from learning to extract orientation-invariant information or from learning view-specific representations at the trained orientations. We contrasted these approaches by examining repetition priming for prime-target pairs presented on successive trials in either the same orientation (horse at 51 degrees primes horse at 51 degrees) or a different orientation (horse at 154 degrees primes horse at 51 degrees), for two subgroups of subjects. One subgroup showed no orientation effect, even when unpracticed, and a correspondingly high generalization of priming across different views. The other subgroup initially showed high sensitivity to misorientation and little priming across orientations but, with sufficient practice, came to show no orientation effect and complete generalization of priming. Thus, some subjects always used orientation-invariant procedures, whereas others learned to do so.

Adult↗
PubMed2003

Dorsal stream activation during retrieval of object size and shape.

We investigated dorsal visual stream involvement in the retrieval of a variety of visual attributes of common objects, using functional magnetic resonance imaging. Seven subjects made binary decisions about the shape, color, and size of named objects during scanning. Bilateral parietal activity was significantly greater during retrieval of shape and size information than during retrieval of color information. Consistent with a domain-specific distributed model of semantic organization, the finding that dorsal stream activity is associated with size and shape retrieval, as compared with color retrieval, may indicate that both size and shape information are learned partly through dorsally mediated processes, such as visually guided grasping. These results demonstrate that both visual-processing streams (i.e., the ventral "what" pathway and the dorsal "where" pathway) are involved in the storage and/or retrieval of knowledge of object appearance but that, just as in vision, these two pathways may play different roles in conceptual processing.

Adolescent↗
PubMed1998

A satisfaction survey on distance education: a model for educating nurses in the cognitive treatment of patients with addictive disorders.

Nurses need to be educated and trained in the assessment and treatment of substance abuse, because 25% to 50% of their patients struggle with this problem. Cognitive therapy takes a problem-solving approach and can be used independently, or in conjunction with, psychopharmacological or 12-step programs. Course participants who made use of the distant education format found the information they learned helpful in their current practice.

Attitude of Health Personnel↗
PubMedDate not supplied

Health promotion mini-grants: grassroots implementation in New Mexico.

The populations of New Mexico are ethnically diverse, with large Hispanic and Native American components, and live in communities that are geographically dispersed and economically challenged. The University of New Mexico is located in Albuquerque, the state's only major urban area, and houses the state's only academic health sciences center. In 1986, the University received a grant from the W.K. Kellogg Foundation to establish health promotion/disease prevention curricula for health science students and create two Wellness Centers on campus. The Wellness Centers train students to be providers of health information and learn how to counsel and assist people with changing health-related behaviors. A campus-wide employee health promotion program was also implemented. Most of the instructional and service programs initiated by the grant have continued with stable institutional support. A later phase of the project was to encourage other agencies and organizations throughout New Mexico to adopt or expand their own health promotion initiatives. An operating premise of this phase was that local initiatives should respond to locally perceived priorities. To accomplish this, a program of mini-grants was designed to assist in creating health promotion programs within a variety of topic areas. Thirteen mini-grants were awarded to agencies representing diverse groups and cultures throughout New Mexico. Our experience with the mini-grants and the ability of organizations to sustain the activities past the period of grant support are described. The successful use of mini-grants has been reported elsewhere in the literature.

Health Planning Support↗
PubMed2006

Laboratory productivity and the rate of manual peripheral blood smear review: a College of American Pathologists Q-Probes study of 95,141 complete blood count determinations performed in 263 institutions.

CONTEXT: Automated laboratory hematology analyzers are capable of performing differential counts on peripheral blood smears with greater precision and more accurate detection of distributional and morphologic abnormalities than those performed by manual examinations of blood smears. Manual determinations of blood morphology and leukocyte differential counts are time-consuming, expensive, and may not always be necessary. The frequency with which hematology laboratory workers perform manual screens despite the availability of labor-saving features of automated analyzers is unknown. OBJECTIVE: To determine the normative rates with which manual peripheral blood smears were performed in clinical laboratories, to examine laboratory practices associated with higher or lower manual review rates, and to measure the effects of manual smear review on the efficiency of generating complete blood count (CBC) determinations. DESIGN: From each of 3 traditional shifts per day, participants were asked to select serially, 10 automated CBC specimens, and to indicate whether manual scans and/or reviews with complete differential counts were performed on blood smears prepared from those specimens. Sampling continued until a total of 60 peripheral smears were reviewed manually. For each specimen on which a manual review was performed, participants indicated the patient's age, hemoglobin value, white blood cell count, platelet count, and the primary reason why the manual review was performed. Participants also submitted data concerning their institutions' demographic profiles and their laboratories' staffing, work volume, and practices regarding CBC determinations. The rates of manual reviews and estimations of efficiency in performing CBC determinations were obtained from the data. SETTING: A total of 263 hospitals and independent laboratories, predominantly located in the United States, participating in the College of American Pathologists Q-Probes Program. RESULTS: There were 95,141 CBC determinations examined in this study; participants reviewed 15,423 (16.2%) peripheral blood smears manually. In the median institution (50th percentile), manual reviews of peripheral smears were performed on 26.7% of specimens. Manual differential count review rates were inversely associated with the magnitude of platelet counts that were required by laboratory policy to trigger smear reviews and with the efficiency of generating CBC reports. Lower manual differential count review rates were associated with laboratory policies that allowed manual reviews solely on the basis of abnormal automated red cell parameters and that precluded performing repeat manual reviews within designated time intervals. The manual scan rate elevated with increased number of hospital beds. In more than one third (35.7%) of the peripheral smears reviewed manually, participants claimed to have learned additional information beyond what was available on automated hematology analyzer printouts alone. CONCLUSION: By adopting certain laboratory practices, it may be possible to reduce the rates of manual reviews of peripheral blood smears and increase the efficiency of generating CBC results.

Blood Cell Count↗
PubMedDate not supplied

Communicating more effectively.

Communicating is something people take for granted. But some organizations have still not learned that information should not be a closely guarded commodity, but something to be shared freely. To be productive, employees must know the organization's goals and constraints. Managers must develop an early warning system so little problems do not grow into big ones. They must be able to assess their employees' morale and prevent personality problems from getting out of hand. In this issue, we asked some top communicators for their tips on promoting better information exchange.

Arizona↗
PubMed1999

[Erectile dysfunction: an educational program].

Erectile dysfunction or impotence is a frequent disease which provokes an alteration in the well-being of those patients who suffer from it and consequently causes distortions, both in a private and a social context, leading to an alteration in the Gordon Health Standard. Our program is geared to all those patients to whom intracavernosum injections of vasoactivating drugs have been prescribed as alternate therapy to solve their erection problem by means of providing information, education, learning, training, control and follow-up in the development of this pathology as well as in its treatment.

Erectile Dysfunction↗
PubMedDate not supplied

Ready or not: assessing youths' preparedness for independent living.

This article discusses the utility of the Ansell-Casey Life Skills Assessment (ACLSA) in assessing life skills necessary for living successfully in the community upon emancipation from out-of-home care. ACLSA, completed by youths and their caregivers, identifies skills that have been mastered and those yet to be learned. Assessment information can be used for goal setting, strength identification, and relationship building, as well as to direct program planning and training in self-sufficiency services.

Activities of Daily Living↗
PubMedDate not supplied

Feasibility of using an alcohol-screening and health education system with older primary care patients.

BACKGROUND: This study evaluated the feasibility of a combined alcohol-screening and health education system for elderly patients METHODS: The Computerized Alcohol-Related Problems Survey (CARPS) was evaluated in primary care practices among 106 current drinkers, 60 years and older. The CARPS contains (1) a self-administered screening survey; (2) software to scan or hand-enter survey responses; (3) software to process data and electronically generate reports of patients' drinking risks; (4) health education; and (5) a database useful for clinical and quality improvement purposes. RESULTS: Nearly all study participants were able to complete the CARPS while waiting for a prescheduled appointment with their physician. There were 44% of patients who were hazardous and 9% who were harmful drinkers. About 20% of men and 26% of women were binge drinkers. Most (85%) patients agreed that alcohol is an important topic, 67% reported learning new information, 78% had never discussed drinking with a physician, and 31% intended to do so. After reviewing CARPS data, physicians concluded that alcohol use in the elderly is an important quality improvement topic. CONCLUSIONS: Combined screening and health education systems appear feasible for use in practice if they deal with pertinent health problems such as alcohol use. Their data can encourage discussions between physicians and patients and might be used for quality improvement activities.

Aged↗
PubMed2001

Differentiation of deception using pupillary responses as an index of cognitive processing.

The deception literature has predominantly focused on detection of guilty individuals using electrodermal measures. Little research has examined other psychophysiological measures or the mechanisms underlying deception. Therefore, the present study examined pupillary responses in a differentiation-of-deception paradigm. Twenty-four undergraduate participants answered the same questions twice, once truthfully and once deceptively, while pupillary responses were recorded. Questions were based on recently learned (episodic) information from scenarios or on general (semantic) knowledge from long-term memory. Task-evoked pupil dilation was significantly greater when participants confabulated responses than when they told the truth for both episodic and semantic memory questions. Previous research has demonstrated that pupil size increases with increased cognitive processing load. The present study suggested that generating deceptive recall was associated with increased pupil size and required greater cognitive processing than truthful recall.

Adult↗
PubMedDate not supplied

[Neuropsychological assessment in posttraumatic amnesia disorder].

INTRODUCTION: The neuropsychological evaluation of memory is an essential investigation in all patients with head injuries, since alterations occur in a high proportion of injured persons and are one of the commonest sequelae. OBJECTIVE: To analyse aspects of the neuropsychological evaluation of memory in head injuries, and the influence of other factors on memory. DEVELOPMENT: Regarding the study of memory capacity, other aspects relative to the presence or absence of posttraumatic amnesia (its characteristics and duration), lacunar-type disorders, retrograde amnesia, anterograde amnesia, ability to learn new information and the position of explicit and implicit memory should be considered. We analyze the instruments for measurement most commonly used for neuropsychological evaluation of memory in patients with head injuries, and the main batteries, tests and scales used for objective evaluation of the presence or absence of memory deficit. We review the main limitations and methodological problems presented by the tests and scales for measurement in this type of population. The instruments of measurement, except for those adapted for the detection of common alterations in head injuries often present serious problems when used to detect posttraumatic deficits. CONCLUSION: Clinically, evaluation of memory should show a profile of the patient's capacities, measure the changes in memory function over time, and predict memory function in everyday activities.

Amnesia↗