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[Use of helium-cadmium lasers in the complex treatment of suppurative diseases in patients with diabetes mellitus].

Study of 174 patients with various suppurative diseases and diabetes mellitus showed that treatment with helium-cadmium laser beam with a wave length of 441.6 nm by a single exposure to 4.5 J leads to rapid abatement of the inflammatory reaction, cleansing and acceleration of the regeneration processes in the purulent wounds, expands the possibilities of surgical treatment with good functional and cosmetic results of plastic operations, which reduces the time of complete wound healing by 1.5 times.

Adult↗

[X-ray irradiation of donor blood in the complex treatment of suppurative diseases].

The authors discuss the use of donor blood after isolated exposure to X-rays in the complex treatment of 65 patients with various suppurative diseases. The therapeutic complex included in all cases transfusion of 250 ml of irradiated blood and subsequent antibiotic therapy. Study of antibiotic (penicillin) pharmacokinetics showed increase of its biological activity and prolongation of its presence in the blood in therapeutic concentrations for 24-48 hours. A scheme of antibiotic therapy in transfusion of irradiated blood is suggested. A formula for calculating the optimal irradiation dose is given. It is concluded that transfusion of irradiated blood followed by injection of an antibiotic raises the efficacy of antibiotic therapy, reduces the term of treatment, and increases the effect of postoperative management.

Adolescent↗

[Complex prevention of suppurative complications of long surgical procedures using microsurgical technics].

The authors have demonstrated the efficacy of complex approach to the solution of the problem of postoperative infectious complications in prolonged surgical interventions with application of microsurgical technique in orthopaedic and traumatologic patients. A reduction in the course of prophylaxis with antibiotics in this category of the patients has been substantiated. The use of metabolite therapy in the course of presurgical preparation of the patients under the control of cytochemical investigations allows to carry on the surgery with a more favourable state of the macroorganism. The use of supersonic cavitation for antibacterial treatment of the operative wounds in prolonged interventions with application of microsurgical technique has no specific contraindications. The complex of these measures has allowed to reduce the rate of suppurations after prolonged surgical interventions with application of microsurgical technique from 23.01 to 8%.

Adolescent↗

[Suppurative meningitis in 210 cases].

Clinical course, etiology and the results of treatment of the suppurative meningitis in 219 adult patients are discussed. Clinical course was extremely severe in 63.3% of the patients, moderately severe in 33.8% of the patients, and complicated by various coexisting disorders and skull trauma in several patients (35.7%). Mortality rate was 8.6%. Combined therapy with 2 or 3 synergetically acting antibiotics was administered. An emphasis is on diagnostic problems especially in patients treated with various antibiotics prior to hospitalization (37.1%) and low percentage of bacteriological tests (22.9%).

Adolescent↗

The aching head. Intracranial suppuration due to head and neck infections.

Many infections of the head and neck may progress to cause more serious suppurative complications that involve the brain and its associated structures. Because many, if not all, of these infectious diseases present as headache, it would be appropriate to discuss all these clinical entities, but because of space limitations, this article focuses on brain abscess, subdural empyema, and cranial epidural abscess. These three pyogenic infections are reviewed in relation to their causal relationship to common and important pericranial infections.

Bacterial Infections↗

[Pseudomonas aeruginosa and Proteus antigenemia and antibody formation in mono- and mixed infections in patients with suppurative inflammatory diseases].

P. aeruginosa and Proteus antigenemia and antibody production have been studied in 335 patients with purulent inflammatory diseases. The study has revealed that in the association of P. aeruginosa and Proteus with staphylococci and representatives of the family Enterobacteriaceae the level of antigenemia is considerably lower than in monoinfections or in the association of these microorganisms with streptococci. In mixed infections humoral immune response develops later than in cases of monoinfection. An important role of ecological and physiological relationships between microorganisms in the course of purulent processes and in their influence on the host has been confirmed. The use of the enzyme immunoassay in the clinical practice has made it possible to determine the etiological role of P. aeruginosa and Proteus in the development of suppurative-inflammatory diseases, to select adequate immunotherapy, including the use of anti-P. aeruginosa and anti-Proteus plasmas, and to evaluate the effectiveness of treatment.

Adolescent↗

Acute bilateral suppurative parotitis due to Haemophilus influenzae. Report of two cases.

Acute bilateral suppurative parotitis developed in two patients with documented cirrhosis of the liver while they were in the hospital. Gram's stain and culture of purulent material obtained from the orifice of Stensen's duct disclosed Haemophilus influenzae as the sole isolate. Both patients were treated successfully with local care and antibiotics. To our knowledge, with one possible exception, infection of the parotid gland due to this organism has not been described previously.

Acute Disease↗

[Obturator shunting in suppuration of vascular prostheses].

An experience with using obturatory shunts in 10 patients with suppurations of vascular prostheses after reconstructive operations on the aorto-iliac segment for its occlusive lesion is presented. The authors have come to a conclusion that extra-anatomical shunting through the closing inlet of the pelvis when combined with resection or removal of the infected vascular prosthesis, local and general antibacterial therapy is an effective method of treatment of the pathology in question. The modified method of shunting facilitates performing the operation in most critical patients. Good results were obtained in 7 of 10 patients operated upon. Two patients died. The amputation of the extremity was fulfilled in 1 patient.

Adolescent↗

Pleuropulmonary suppurations.

The neonatal pleural empyema, especially in its most serious form, following staphylococcal pneumonia, presents a surgical problem demanding immediate emergency treatment. In 1957, we proposed that after diagnosis the empyema should immediately by drained by intercostal suction although in those times drainage was only an attempt after numerous aspirations. Children treated for pleural suppuration in the past were subjected to follow-up studies over a period of 14 to 15 years. Two comparative groups of "early-drained" and "late-drained" empyema cases showed that after immediate drainage there was definite improvement. Careful study of all the data of our 273 cases (up to 1970) shows that immediate continuous suction drainage with specific antibiotic and general supportive treatment have been very successful.

Adolescent↗

[Microbiological evaluation of the methods of preventing suppuration of surgical wounds].

Contamination of the operative wounds with aerobic and nonsporulating anaerobic microflora is known to take place in the process of operation. Lower degree of the contamination of the operative wounds by the end of operations results in lower incidence of suppurations. It can be achieved in pure and conventionally pure operations of a less traumatic character by the application of preoperative gentamycin electrophoresis onto the operation field, while in conventionally pure operations of great traumatism and contaminated operations--by active irrigating drainage.

Disinfection↗

[Suppurative parotitis caused by a foreign body in a 4-year-old child].

The authors report a case of unilateral acute suppurative parotiditis in which the endo-buccal examination allowed the removal of a hair from the parotid duct. The histologist demonstrated that the hair belonged to the child and that its removal was sufficient to ensure cure.

Child, Preschool↗

[Treatment of acute bilateral suppurative lung diseases complicated by pyopneumothorax].

An analysis of the complex treatment of 33 patients with acute bilateral suppurative diseases of the lungs complicated by pneumothorax has been made. It has been proved that early pleurectomy with resection of the lung is possible in a number of patients with such a pathology. Indications to surgery were established and a comparative analysis of conservative and surgical methods was made.

Acute Disease↗

Perianal suppuration: results of treatment.

Perianal suppuration (PAS) is a common surgical problem that is frequently treated inadequately. A series of 101 patients with PAS was reviewed. Thirty-six patients had a history of PAS. Fifty patients had drainage of a perianal abscess; six patients developed fistulas in ano and in two recurrent abscess developed (total, 16%). Thirty-six patients had fistulotomy for established anal fistula: three patients (8%) had recurrent fistulas. Fifteen patients had single-stage drainage of abscess and fistulotomy, and none had recurrent or residual PAS. All patients ultimately achieved healing. These results illustrate the fact that satisfactory results in the treatment of PAS can be obtained by surgeons if established principles of treatment are observed.

Abscess↗

[Fibrous suppurative arthritis in sheep].

Described are cases of fibrinous supprative arthritis in sheep characterized by thickenning of the joint, resulting from the involvement of the capsule (periarthritis). Histopathologically, there have been suppurative and necrotic processes combined with fibrinoid necrotizing of the collagen fibers and leukocyte infiltration of the joint capsule. Slight leukocyte infiltration has also been said to occur in the parenchymal organs. Microbiologic studies have revealed the presence of pyogenous bacteria (Corynebacterium pyogenes, Streptococcus pyogenes, Pasteurella multocida).

Animals↗

[Suppurative-destructive complications of acute pneumonia and the principles of their treatment].

Peculiarities in the development and course of purulent complications in patients with acute pneumonia require a differentiated approach to therapy. The control of clinicoroentgenological stages of the abscess formation of pneumonia taking account of the peculiarities of a purulent process in each patient permits one to resort to differentiated therapy and to plan therapeutic measures until a complete cure of a patient. Effective treatment of a patient with lung suppuration is based on the suppression of purulent infection by massive antibiotics therapy combined with measures aimed at enhancing the defence activity of the body. Of paramount importance at the final stage of therapy is stimulation of reparative processes in the zone of destruction with physical therapeutic factors. Physiotherapy employed in combination with therapeutic measures raises the recurrences and change into a chronic state. Patients after pulmonary abscess formation should be followed up for 1.5-2 yrs.

Acute Disease↗

[Structure of the microflora of suppurative wounds and its sensitivity to antibiotics].

Clinico-bacteriological examination of patients with purulent infections showed that Staphylococcus was the predominating microflora in the wounds. Simultaneously an increasing role of gram-negative conditionally pathogenic bacteria was shown. Multiple drug resistance was found in the organisms tested. The highest sensitivity levels were observed to gentamicin, kanamycin, tetracycline, levomycetin. It was shown by means of special typing methods that staphylococci of phage group III and Ps. Aeruginosa of serotype II predominated in the infected wounds. When the pathological material contained the antibiotic resistant cultures of Ps. aeruginosa, Proteus, Klebsiella and toxigenic strains of Staphylococcus, a tendency for prolongation of the suppurative process was observed.

Abscess↗

[Protein metabolic disorders in patients with suppurative lactation mastitis].

On the basis of studying protein metabolism in 89 patients with suppurative lactation mastitis it was shown that the concentration of total protein in blood serum did not depend on the degree of the clinical course of the disease, the substantial changes in protein fractions being in direct relation to the degree of the clinical severity of the disease.

Acute Disease↗