The disability in hemiplegia caused by cerebrovascular disease: serial studies of 98 cases.
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Unawareness of motor and visual-field defects was investigated in 97 right brain-damaged subjects. Both kinds of anosognosia were found to be double-dissociated from more elementary neurological disorders and from personal and extra-personal neglect. The relationships between anosognosia and unilateral neglect are discussed and allusion is made to the implications concerning the neurological organization of higher control functions.
A young female harbored a large arteriovenous malformation (AVM) in the basal ganglia associated with marked arteriovenous shunting. The complete recovery of her neurological deficit subsequent to excision of the AVM illustrates the reversibility of such severe cerebral impairment. Large lesions in the basal ganglia often have been deemed inoperable. However, modern advances in microsurgical techniques have provided the necessary illumination, magnification, and instrumentation that was needed for the exposure and gentle resection of the lesion in our patient.
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A case of hypoglycemic hemiparesis in a fifteen-year-old girl with insulin dependent diabetes mellitus (IDDM) is described. The initial presentation included left facial paresis and muscular weakness of the left upper and lower extremities, associated with a blood glucose level of 31 mg/dL. The patient recovered completely after a glucose infusion. Her neurological examination became normal within 24 hours and remained so for a follow-up period of 6 months. Hypoglycemic hemiparesis is rarely described in children and adolescents.
Diaschisis is a functional impairment at a site in the brain remote from the lesion causing it. An investigation of cerebellar diaschisis in childhood was undertaken to better understand the functional maturation of the corticopontocerebellar tract in developing brain. A retrospective study of cerebellar diaschisis in 55 hemiplegic children was conducted using single-photon emission computed tomography (SPECT) with 123I-IMP. Cerebellar diaschisis was evaluated by 2 authors. Crossed cerebellar diaschisis (CCD) was found in 6 of 55 patients. SPECT findings of patients who presented with CCD disclosed supratentorial hypoperfusion of varying degrees, from focally to the whole hemisphere; however, patients had frontal and/or parietal hypoperfusion in common. A second type of cerebellar diaschisis also was demonstrated. Cerebellar hypoperfusion ipsilateral to supratentorial lesions, ipsilateral cerebellar diaschisis (ICD), was observed in 10 of 55 patients. CCD occurred in the patients who suffered from brain injuries after 7 years, 5 months of age, while ICD manifested in patients whose brain injuries occurred before 3 years, 1 month of age. The production of remote effects, such as CCD and ICD, could be closely related to maturation of the corticopontocerebellar tract in the developing brain during childhood.
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After long term of studies from our gait lab, the typical muscular dysbalances by all of our patients with cerebral palsy where pointed out. Now we wanted to examine using the MRT, weather the dysbalances of the hemiparetic musculoskeletal system also show up in discrepancies of the muscle volumes. The MRT slices of the lower extremities were segmented. From this cross sections the muscles volumes were derived. These where analyzed particularly with regard to asymmetries between spastic and healthy side. Hemiparetic patients showed reduced volumes of all muscles on the paretic leg in comparison to the healthy side. The muscles of the thigh of the paretic leg were reduced to 84% in the mean over all muscles and in comparison to the healthy leg. The volume of the muscles of the shank was reduced to 72%, significantly more than the muscles of the thigh. Concerning flexor and extensor muscles located at thigh and shank of the paretic leg there was found significantly the same relative deficit of the muscle volume. Examining the muscle volumes of subjects with different neurogene foot deformities, significant differences of the volume reduction of single muscles appeared within the lower leg.
OBJECTIVE: Analysis of a precision grip-lift task provides measures to assess functional disability of the hand, but the correlation between these measures and accepted tests of motor function in stroke patients has not been established. METHODS: Seventeen subacute stroke patients were studied to compare parameters of a precision grip-lift task between the affected and unaffected side, and to correlate them with function. Functional impairment was assessed with the Action Research Arm Test and the Fugl-Meyer assessment, as well as grip strength and maximal finger-tapping speed. The grip force (GF) and load force (LF) were recorded as patients lifted a custom-built manipulandum. All measures were recorded on two separate occasions, at least 1 week apart. RESULTS: There was good reproducibility between testing sessions for the grip-lift and functional measures. The affected hand gripped the manipulandum for longer prior to lift-off than the unaffected hand, and the normal close temporal coupling between the rate of change of GF and LF during the lift was disrupted. These two measures correlated more highly with the ARAT than the FMA and, when combined with measures of grip strength and tapping speed, explained 71% of the variance of the ARAT. CONCLUSIONS: The grip-lift task is a sensitive measure of impaired dexterity following stroke and provides measures which correlate well with a commonly applied functional assessment scale. SIGNIFICANCE: This task may be used clinically to detect changes in the hemiplegic upper limb during rehabilitation and recovery.
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The repeatability of both 3D kinematic measurements of arm movement during simple upper limb tasks and lower limb movement during gait analysis was evaluated in 10 children with hemiplegic cerebral palsy. All tasks were completed on two separate occasions, 1 week apart. The 3D lower limb gait analysis showed high levels of repeatability in the sagittal plane measures, with mean coefficient of multiple correlations (CMCs) greater than 0.92 between sessions. Transverse and frontal plane measures had mean CMCs greater than 0.7 between sessions. A 3D analysis of shoulder and elbow flexion/extension during the two functional tasks (hand to head and hand to mouth) was highly repeatable between sessions (mean CMCs, 0.87 to 0.95). Rotational measures at the shoulder and the elbow during the same tasks demonstrated moderate levels of inter-sessional repeatability (mean CMCs shoulder 0.49 to 0.63; elbow 0.63 to 0.74). Overall, the lower limb 3D kinematic analysis had similar levels of repeatability in both the hemiplegic limb and the limb with normal tone. The 3D kinematic analysis of movement of the hemiplegic upper limb during simple upper limb tasks also had moderate to good repeatability, suggesting it may be able to be used as an outcome measure in the hemiplegic upper limb.
INTRODUCTION: We report the case of a 48-years patient who is under chimotherapy because of a breast cancer. She was initially found at her place in coma with hyperthermia and neurological deficiency signs. The clinic history and the paraclinical investigations have enabled to detect a catheter-related infection (CRI) as soon as the diagnosis of disseminated infectious endocarditis was made. The resonance imaging confirmed the cerebral blow when it found suspicious images of septic embolus. EXEGESIS: The CRI are usually detected at an early stage and if the classical association CRI-infectious endocarditis-systemical embolus is well known, the discovery on a CRI not treated at the stade of a febril coma is exceptional. CONCLUSION: More than ever the taking care of infectious endocarditis, still delicate and sometimes perilous, requires a global taking care of the patient.
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OBJECTIVES: 1. To determine if scapular and humeral orientation differed between the affected and nonaffected side in two groups of hemiplegic subjects (low tone and high tone). 2. To determine if there was a relationship between these measures and glenohumeral subluxation in either group. DESIGN: Retrospective case-comparison study. SUBJECTS, SETTING: Thirty-four hemiplegic subjects, 41 to 89 years of age, participated in the study. Subjects were divided into high-tone (n = 17) and low-tone (n = 17) groups on the basis of Ashworth scoring of muscle tone. OUTCOME MEASURES: Linear and angular measures of scapular and humeral orientation were calculated from tridimensional coordinates of bony landmarks collected using an electromagnetic device with subjects in a seated position with arms relaxed by their side. Glenohumeral subluxation was measured from radiographs. RESULTS: The scapula was further from the midline and lower on the thorax on the affected side in the low-tone group (p < .05). Glenohumeral subluxation was greater in the low-tone group (p < .05). The scapular abduction angle (ScAb) was significantly greater on the nonaffected in the low-tone group compared with both the affected side in this group and to the nonaffected side in the high-tone group. In the high-tone group, no differences were found between the affected and nonaffected side in either the angular or linear measures. There was no significant correlation between scapular or humeral orientation and glenohumeral subluxation in either group (p > .05). CONCLUSIONS: This study provided little evidence of a consistent pattern of alteration in shoulder complex orientation, particularly in subjects with increased muscle tone, and no support for the concept of a relationship between scapular and humeral orientation and glenohumeral subluxation.