SEARCH · PubMed Health

Results for “parotidectomy”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 847 records · Page 47Linked to original sources

PubMed2005

[The interesting case -- case no. 68. Metastasis of a small-cell bronchial carcinoma to the parotid gland].

We present a case of a metastasis to the parotid gland from a small cell carcinoma of lung. The patient noted swelling in right parotid region without pain and saw an otorhinolaryngologist. There was no facial nerve palsy. He was admitted to our hospital. The total parotidectomy with facial nerve preserving was performed. The pathological findings indicated small cell carcinoma. After receipt of this report, we examined the lungs. An abnormal shadow could be found in the chest X-rays. CT revealed a lung tumor on a left site which was determined to be small cell carcinoma by transbronchial lung biopsy. Metastasis to the parotid glands from any distant primary site is quite unusual. In most cases of secundary parotid involvement of malignant tumors primary tumors originated from the head and neck region. Primary tumors in the neighborhood are the skin of the head and neck and the mucosa of the upper airway and digestive tract. Distant metastases to the parotid gland have been reported to arise from bronchial carcinoma, renal carcinoma, colonic carcinoma, prostat and breast. The distinction between primary salivary glands tumors and metastases of other primary tumors is difficult often. Histologic and immunhistological methods can be helpful.

Biomarkers, Tumor↗

PubMed2006

[Distant metastases on acinic cell carcinoma of the parotid gland after 12 years symptom-free interval].

Acinic cell carcinoma of parotid gland as cause of distant metastases are rare. The patient was a 60-year-old woman who had in 1993 a acinic cell carcinoma of right parotid gland. Tumour can be resected through total parotidectomy with facial nerve anastomosis and modified radical neck dissection (T (3) N (2b) M (0)). Since the operation the patient has remained symptom-free without any sign of tumour recurrence. After 12 years the patient noted swelling in the region of sternum and biopsy was necessary. Histologically and immunohistochemically the diagnosis of distant metastase on acinic carcinoma of the parotid gland was confirmed.

Biopsy↗

PubMed2006

[Sebaceous carcinoma of the eyelids--case reports and review of the literature].

BACKGROUND: Sebaceous carcinomas are among the most rarely found skin tumours (0.2 - 4.6 %). As with most skin tumours the predominant region of occurrence is the head and neck, in particular the eyelids. The cytological origins are foremost the Meibomian and the glands of Zeis. CASE REPORTS: We report on two female patients suffering from sebaceous carcinoma of the upper and lower lid. The time span from initial treatment up to definite diagnosis and treatment was one year. In both cases the tumour was radically removed surgically and the eyelid reconstructed. In the first case there was no tumour recurrence within six years after surgery. In the second case a lymph node metastasis of the parotid gland was found seven years after initial therapy and surgically removed followed by a complete parotidectomy and neck dissection. DISCUSSION: As the sebaceous carcinomas are difficult to differentiate from other kinds of benign and malignant eyelid diseases, a considerable delay between the initial examination and final diagnosis is not uncommon. This type of tumour is characterised by a high degree of biological aggression concerning local recurrence and lymphogenous and hematogenic tumour spread. The mortality rate is reported to be between 9 and 40 %. Therapy of choice is the radical surgical removal of the tumour. Depending on preoperative findings, neck dissection may be indicated. The biological behaviour of this kind of tumour requires long-term oncological aftercare.

Adenocarcinoma, Sebaceous↗

PubMed1996

Cross-facial nerve grafting for facial reanimation: effect on normal hemiface motion.

Reinnervation of the paralyzed hemiface with a cross-facial nerve graft (CFNG) required division of facial nerve branches on the normal hemiface to serve as axon donors. There is therefore concern about whether any impairment of normal hemiface motion occurs in the postoperative period. To minimize the likelihood of donor-side impairment, donor branches are chosen from the bucco-zygomatic region which was extensive cross branching, as opposed to be the single temporal or marginal mandibular branches. This study chose to determine quantitatively if this practice does, in fact, adversely affect the normal side hemiface motion governed by these branches, viz., eye closure, pucker, and smile. Since surgical procedures near the facial nerve (such as superficial parotidectomy) may leave the patient with transient facial weakness, even in the absence of nerve transection, the hypothesis was that hemiface motion would be impaired on the donor side during the early postoperative period (first month) secondary to edema and/or neuropraxia. However, based on the clinical observation that donor-side facial motion is not demonstrably impaired late after surgery, a further hypothesis was that any early facial motion is not demonstrably impaired late after surgery, a further hypothesis was that any early facial motion impairment would return to normal by 3 months postoperatively. Seven patients underwent sural CFNG as a primary or secondary component of their facial animation procedure. Their facial motion was quantified preoperatively and in serial postoperative examinations using the Maximal Static Response Assay (MSRA) of facial motion. Careful selection of redundant bucco-zygomatic branches of the facial nerve on the normal side for CFNG did not ultimately ( > or = 3 months postoperative) impair the important motions of eye closure, smile, or pucker. Early postoperative ( < or = 1 month) weakness of the smile was seen on both X and Y axes, indicating that both the risorius and zygomatic muscles were transiently weakened. The ability to elevate the lower eyelid was unaffected at any postoperative time point. Movement of the normal hemiface did not appear to be permanently affected by CFNG when a careful choice of redundant bucco-zygomatic donor branches was made.

Adult↗

PubMed1999

[Intraductal papilloma of the parotid gland].

BACKGROUND: This rare intraductal papilloma of the salivary glands is classified as an adenoma of the subgroup ductal papillomas. The nature of intraductal papillomas has not been fully researched. It is assumed that the intraductal papilloma arises from the excretory duct reserve cell population. Since the lesion was first described, 9 cases have been reported. CASE REPORT: An additional case of intraductal papillomas of the parotid gland is presented: a 62-year-old woman with a solid and well displaceable tumor of the left preauricular region. After a standard superficial parotidectomy was performed the histological examination revealed an intraductal papilloma. RESULT AND CONCLUSION: The case represents the first published case in German literature. This study presents a review of the literature and a discussion of the histopathologic characteristics and possible histogenesis of the intraductal papilloma. Regular follow-up has not revealed any recurrence of the disease 15 months after resection. The treatment of choice is local excision or removal.

Female↗

PubMed1994

[Cystic lymphoepithelial lesions in the head and neck area in HIV-infected patients].

Benign lymphoepithelial cysts (BLC) are rare disorders of salivary glands (0.6%). In patients infected by HIV, they are seen more often. In comparison to sporadic BLC, the patients are younger, the diameter of the cysts is up to 5 cm and they are often located bilaterally. At the Department of ENT, Head and Neck Surgery of the Ludwig-Maximilians-University, Munich, ten HIV-infected patients (two females) showed lymphoepithelial cysts (six times bilaterally). One of these revealed a metastasis of a small cell neoplasma near the cysts, another patient showed a non-Hodgkin's lymphoma of low grade malignancy (MALT-type), and one patient additionally had bilateral Warthin's tumours. The BLCs were mostly located in the parotid tail. In three cases, the cysts were found on the inferior border of the parotid and once at the submandibular gland. The age ranged from 27 to 71 years (medium 45.7 years). The mode of HIV infection was homosexuality five times, drug abuse twice, heterosexuality once, and blood products once. In two cases, the channel of transmission was unknown. The majority of the patients showed minor HIV illness (CDC II [n = 2]/CDC III [n = 4]); the rest had advanced immunodeficiency (CDC IV [n = 4]). All the cysts were examined by ultrasonography and NMR. According to the clinical findings and the general stage of health, BLCs were either enucleated (n = 8) or a superficial parotidectomy (n = 5) and selective biopsy of lymph nodes (n = 3) suspected to be malignant were performed.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

PubMed1998

[Case report of epithelioid hemangioendothelioma of the frontal region metastatic to the parotid gland].

BACKGROUND: The epithelioid hemangioendothelioma is a soft tissue tumor of vascular origin. Typical localisations are subcutis, cutis, liver, lungs and bones. It has been described in 1982 by Weiss and Enzinger as a separate tumor entity. Due to the unpredictable biological behaviour of the tumor, a borderline malignancy is assumed. CASE REPORT: We report on the case of a 44-year old woman with a metastasising epithelioid hemangioendothelioma in the head and neck area. The primary tumor was located in the subcutis of the left forehead. Due to local recurrences surgical treatment was performed three times after the initial removal in 1993. At the time of the last local recurrence in 1996, a tumor in the left parotid gland was diagnosed and was the reason for a lateral parotidectomy. Pathohistologically, a metastasis of the epithelioid hemangioendothelioma was found. Postoperative radiotherapy was performed and no recurrence occurred until now (22 months follow-up). CONCLUSION: Metastatic epithelioid hemangioendotheliomas are rarely found in the head and neck area. Literature has not yet reported on metastasis formation in the parotid gland. The case illustrates the potentially malignant behaviour of epithelioid hemangioendotheliomas. Hence, therapy should consist of a combination of radical tumor removal and post-operative radiotherapy.

Adult↗

PubMed1992

[Perioperative single dose prevention with cephalosporins in the ENT area. A prospective randomized study].

Perioperative systemic antibiotic cover is usually recommended in major head and neck surgery with the aim of preventing postoperative wound infection. The surgeon must administer the drug most suitable for the particular operation and patient at an adequate dosage and over an adequate period. On the other hand, he has an obligation to minimize costs and find ways of avoiding the development of bacterial resistance to the antibiotic. This means that prophylactic antibiotics may not have too broad an antibacterial spectrum and may only be used over the short term. In an attempt to improve antibiotic prophylactic in head and neck surgery, we tested the effectiveness of a perioperative single-dose antibiotic cover with cefuroxim (Zinacef) in patients undergoing parotidectomy, sinus surgery or neck dissection with no transcutaneous exploration of the pharynx. This single-shot prophylaxis was compared with a three-shot, 24-hour regimen using the same antibiotic. The two regimens were equally effective in preventing wound infection and no case of infection was observed among the 106 patients involved. Preoperative concentrations of cefuroxim were measured in serum and tissue, and the large majority of specimens showed effective concentrations against the typical wound infection bacteria. In conclusion, a perioperative single-dose administration of cefuroxim proved to be suitable prophylaxis against postoperative wound infection in head and neck surgery.

Cefuroxime↗

PubMed1992

[Chronic recurrent parotitis in childhood].

Juvenile recurrent parotitis (j.r.p.) is distinguished from the adult form by the course of the disease, therapeutic considerations and prognosis. Children suffering from j.r.p. are between 2 and 15 years of age; the male: female ratio is 1.5:1. In the present paper the author describes the different pathogenic theories of j.r.p. in accordance with the relevant literature. Besides malformation of the glandular duct like stenosis and ectasis, functional factors like the character of salivary secretion are suspected as being responsible for the disease. Other authors assume that a viral genesis, allergic factors, a physiological immaturity of the immune response, or family history may be the causes. In the evaluation of children with j.r.p. the patients' history with recurrent swelling episodes of the parotid gland(s) followed by quiescent periods is indicative. Further procedures like ultrasonography, sialography and MRI are discussed according to their diagnostic value. Therapeutic possibilities include antibiotics in the acute stage of the disease as well as parotidectomy in severe cases. Radiotherapy cannot be recommended because of its side effects (facial dysplasia, tumour induction). In most cases, the disease ends at puberty.

Child↗

PubMed1997

[Tuberculosis of the parotid gland: a rare differential diagnosis of parotid tumor].

BACKGROUND: Mycobacterial infection of the parotid gland is rare even in countries where the disease is rife. Because patients do not have specific symptoms of tuberculosis and tuberculosis of the parotid gland frequently presents as a neoplasm, most patients undergo parotidectomy. PATIENTS: In this text we present a case report and the review of 20 well documented cases from the literature. The problems of diagnosis and therapy, especially the problem of distinguishing tuberculous infection from another parotid swelling such as a benignoma or a granuloma, are analyzed. RESULTS: Eighty percent of the patients we reviewed in our investigation originated from Asian or African countries. In most cases the history of the parotid swelling was shorter than one year, often even shorter than six months. In 17 of the 20 patients tuberculosis presented as a solid mass corresponding to the infection of a parotid lymph node. In three cases a diffuse infection of the whole gland was described. It was frequently impossible to distinguish tuberculosis from swelling of the parotid gland due to other causes by clinical or sonographical investigations. History of tuberculosis was given in two cases: the patients underwent an antituberculous therapy one and five years ago. The chest radiograph was normal in all but one cases. In two cases pretherapeutic diagnosis was made by biopsy, in two cases by fine needle aspiration cytology, which was performed in a total of seven cases. CONCLUSION: Tuberculosis is a rare cause for parotid swelling. Nationality of the patient and a short history of the swelling may suggest a mycobacterial infection. Diagnosis by fine needle aspiration cytology may be difficult. Other investigations should be added, if necessary. Antituberculous therapy has to be done also in cases of organ tuberculosis after surgery. If the right diagnosis is known before therapy, parotictomy can be avoided.

Antitubercular Agents↗

PubMed1996

[Synchronous double tumors of the parotid gland].

BACKGROUND: Synchronous unilateral tumors of the parotid gland are found only rarely. The majority of these are multifocal Warthin's tumors (papillary cystadema lymphomatosum). The incidence is reported to range up to 12%. Malignant processes develop within a pleomorphic adenoma in about 6.6% of all cases. In a few cases, they also develop in a Warthin's tumor. Two coexisting benign parotid tumors of different histologic types are extremely rare. PATIENTS: In this report we present a patient with an unilateral pleomorphic adenoma and a Warthin's tumor. It is the eleventh published case of this kind. The problems of diagnosis, differential diagnosis, and surgical therapy of benign multiple parotid tumors are discussed. The current literature is reviewed. RESULTS: Synchronous multiple Warthin's Tumors or multiple tumors of different histologic types in the same parotid gland are found rarely. Nevertheless careful preoperative diagnosis causing B-mode ultrasound as the primary imaging modality. Meticulous intraoperative inspection and palpation of the glandular tissue and periglandular lymph nodes is indicated. In order to ensure adequate tumor removal, the therapy of choice is a total or subtotal parotidectomy. CONCLUSION: We suggest careful preoperative diagnosis and meticolous intra-operative exploration in order to localize multifocal lesions of benign parotid tumors. This minimizes the chance of overlooking synchronous tumor foci, which would necessitate difficult revision surgery entailing a risk of injury to the facial nerve.

Adenolymphoma↗

PubMed1996

[Epithelioid sarcoma of the parotid region].

BACKGROUND: Epithelioid sarcoma has been described in 1970 by Enzinger as a separate tumor entity. It is a rare soft-tissue tumor mostly found in the distal extremities in young adults. The head and neck region is only very infrequently affected. PATIENT AND RESULT: We report the rare case of a manifestation of an epithelioid sarcoma in the area of the right parotid gland in a 72-year-old patient. Only two more cases with a similar tumor entity and location have been described in the international literature. The patient underwent total parotidectomy, radical neck dissection, and postoperative radiotherapy two years ago and has been free of recurrence since then. CONCLUSIONS: Epithelioid sarcomas of the head and neck are very rare tumors. They are treated by radical local tumor removal, neck dissection, and postoperative radiotherapy. Prolonged postoperative follow-up is necessary since recurrences can occur after up to more than 15 years.

Adult↗

PubMed1995

[Carcinoma of the temporal bone--current diagnostic and therapeutic aspects].

BACKGROUND: Carcinoma of the external ear canal and the middle ear is a rather rare event and is especially seen in patients with chronic inflammatory ear disease. PATIENTS: Between 1993 and 1994, we treated seven patients with such a tumor, of which six proved to be a squamous cell carcinoma and one presumably adenocarcinoma. In three patients, the malignoma developed in a radical cavity of the ear and caused a facial palsy. Only two patients were without any discharge of the ear. Beside facial palsy, hemorrhagic otorrhea and otalgia were the leading symptoms. One patient presented with a bilateral painless swelling of the neck due to lymph node metastasis. Diagnosis was made by means of biopsy in only three patients and on the basis of a resected specimen after mastoidectomy in four patients. Angiography and computed tomography and magnetic resonance imaging studies were performed prior to treatment to determine the extent of the tumor. RESULTS: The tumor was resected by petrosectomy, parotidectomy, and neck dissection in 5 patients. Three times the margins of the histological specimen were free of tumor. Lymph node metastasis in the neck were seen in 5 cases, while distant metastasis did not occur. Two patients underwent primary irradiation, but a postoperative radiation therapy was performed five times. To date, three patients died after one year follow-up. CONCLUSIONS: Carcinoma of the temporal bone is a rare tumor, which can be treated only in case of early diagnosis.

Adenocarcinoma↗

PubMed1993

[Facial paralysis in benign parotid tumor: case report and review of the literature].

Generally, typical symptoms are significant for malignant parotid tumours: The infiltration of surrounding structures and facial paralysis. A case is reported where a benign parotid tumour (lymphadenitis) caused facial paralysis. Parotidectomy and the removal of the lymph node near the stylomastoid foramen led to complete restitution. A review of the literature of the past 40 years mentions 16 cases of benign neoplasms of the parotid gland that caused facial paralysis, such as pleomorphic adenoma, Warthin's tumour, oncocytoma, benign parotid cysts, chronic parotitis, lymphadenitis and parotid abscess.

Adult↗

PubMed2000

Epithelioid hemangioendothelioma of the parotid salivary gland.

Epithelioid hemangioendothelioma is a borderline neoplasm characterized by proliferation of endothelial cells with epithelioid morphology. The tumor, in terms of histology and behavior, occupies an intermediate position between hemangioma and conventional angiosarcoma. It is encountered in a wide variety of sites, such as soft tissues and skin, visceral organs, and bone. This article describes a slowly growing, painful tumor that developed in the parotid gland of a 48-year-old white woman and was treated with a superficial parotidectomy. Microscopically, the lesion consisted of short strands, cords, or small clusters of epithelioid vacuolated cells that exhibited strong immunoreactivity for endothelial cell markers (CD 31, CD 34, and factor VIII-related antigen). Previous reports have presented epithelioid hemangioendotheliomas in the head and neck region but, to our knowledge, this is the first reported case in the parotid salivary gland.

Biopsy, Needle↗

PubMed2002

Histopathologic changes in parotid gland parenchyma after fine needle aspiration biopsy of a Warthin's tumour. A case report.

Fine needle aspiration biopsy of a non-tender tumour in the right parotid gland was performed in a 63-year-old man. A cytological diagnosis of Warthin's tumour was made. Six weeks later, the tumor was removed by a formal parotidectomy. During dissection of the marginal mandibular branch of the facial nerve, significant fibrosis in the surrounding soft tissues was noted, requiring resection of the nerve. We also found a metaplastic (infarcted) Warthin's tumour with focal necrosis surrounded by metaplastic squamous epithelium. There was extensive fibrosis within the adjacent atrophic parotid parenchyma, striated muscle and around peripheral nerves. Small arteries at the periphery of the tumour were occluded by thrombi. The authors believe that the fibrosis of the tissue adjacent to the tumour was more likely due to the ischemia than to a direct puncture trauma caused by the fine needle aspiration.

Adenolymphoma↗

PubMed2004

MALT-type lymphoma and Warthin's tumour presenting in the same parotid gland.

Non-disseminated malignant lymphomas of salivary glands occurring in association with Warthin's tumour have rarely been reported. We describe the first case of association of an extranodal mucosa-associated lymphoid tissue (MALT)-type non-Hodgkin's lymphoma with Warthin's tumour of the parotid gland. Total parotidectomy with preservation of the facial nerve was performed. Surgical and pathological evidence confirmed that the parotid MALT lymphoma did not arise in the lymphoid stroma of the Warthin's tumour. Immunostaining of the MALT lymphoma cells proved negative for Epstein-Barr virus and Helicobacter pylori antibodies and polymerase chain reaction assays did not identify human herpesvirus 8. The patient has been followed up for 11 months, without evidence of recurrent disease. It cannot be ruled out that long-term immunological stimulation by the Warthin's tumour may have caused lymphoid accumulation, chronic stimulation of B cells and extranodal parotid MALT lymphomagenesis.

Adenolymphoma↗

PubMed2005

Valproic acid-associated sialadenosis of the parotid and submandibular glands: diagnostic and therapeutic aspects.

Sialadenosis has been defined as a non-inflammatory, parenchymatous salivary gland disease causing recurrent, bilateral swelling of the salivary glands. As an adverse drug reaction of valproic acid, sialadenosis is very rare. To our knowledge, it has been reported only once in the world literature to date. We present herein the case of a patient with valproic acid-associated sialadenosis of both the parotid and submandibular glands. This appears to be the first published case of a patient who received surgical treatment. On light and electron microscopy of all the affected salivary glands, granular sialadenosis with predominantly moderate electron-dense secretory cytoplasmatic granules was observed. No relevant degenerative alterations were seen. There was no histological evidence of peripheral neuropathy of the nerve supply, leading to disordered activity of acinar cells by loss of neurosecretory granules. Lateral parotidectomy, performed under neuromonitoring control for safety reasons, is the treatment of choice for chronic recurrent parotitis that does not respond to conservative therapy, particularly if the cosmetic deformity is unacceptable to the patient. If the submandibular glands are involved, partial removal is recommended.

Adult↗