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At least 865 records · Page 48Linked to original sources

Treating internal resorption using a syringeable composite resin.

BACKGROUND: Internal resorption is a pathological process initiated within the pulp space with the loss of dentin. It often is described as an oval shaped enlargement of the root canal space and usually is asymptomatic and detectable by routine radiographs. Treatment of internal resorption has included several materials--gutta-percha, zinc oxide eugenol and amalgam alloy. These materials do not provide strength to the tooth structure. CASE DESCRIPTION: A 29-year-old woman was referred to a dental clinic for treatment of a large internal resorptive defect in the coronal and middle one-third of the maxillary left central incisor root with no apparent periapical pathosis, as well as a large periapical radiolucency at the apex of the maxillary left lateral incisor that was associated with a necrotic pulp. The authors used a dual-cure syringable composite resin in conjunction with a bonding agent within the defect to treat it. CLINICAL IMPLICATIONS: This technique seals the dentinal tubules and strengthens the remaining tooth structure. It also improves the outcome of resorptive defects and reduces operators' chair time.

Adult↗

Delivering vaccines into the skin without needles and syringes.

The skin is a highly accessible organ and due to the presence of powerful antigen-presenting cells in the epidermis, it functions as an immune barrier. This makes the skin an attractive route for potential delivery of vaccines by painless and user-friendly methods without the requirement of needles and syringes. This article reviews current attempts to administer vaccines into the skin and discusses some of the scientific issues related to the emerging delivery technologies.

Administration, Cutaneous↗

DNA sequencing using rolling circle amplification and precision glass syringes in a high-throughput liquid handling system.

An automated high-throughput method that employs rolling circle amplification (RCA) to generate template for large-scale DNA sequencing has been developed using liquid handling systems equipped with precision glass syringes. A protocol was designed to perform the sequencing analysis from template preparation to thermal cycle sequencing within the same vessel, thus minimizing the amount of liquid handling and transfer. The amplified DNA was directly used for cycle sequencing with no need for any purification procedures. Total RCA reaction volumes as low as 500 nL generated sufficient templates for successful sequencing. Reducing the RCA total reaction volumes by a 40-fold factor, from a total of 20 microL to 500 nL, resulted in a significant reduction in cost, from $1.25/reaction to less than $0.04/reaction. Additionally, the volume of the sequencing reactions was reduced from a total of 20 to 10 microL, thus generating a further cost advantage. This high-throughput DNA sequencing protocol maximizes the speed and precision of processing while significantly reducing the cost of amplification.

Algorithms↗

A new method for measuring the pneumotachometer characteristics using a syringe.

A new method for determining the nonlinear characteristics of pneumotachometers was developed. This method consists of a computer algorithm analyzing unsteady flows generated by a syringe. We removed the possible influence of the frequency characteristics of the measuring system by inserting an acoustic low pass filter in the path of gas flow. Two types of Fleisch pneumotachometers were tested. For a given volume of 3 l, the error of measured volume is 12.5% in uncorrected series and 0.2% in the corrected.

Algorithms↗

Needle and syringe cleaning practices among injection drug users.

Bleach-mediated disinfection (BMD) of needles and syringes (NS) has been advocated as a risk-reduction intervention against HIV among injection drug users (IDUs). The effect of needle exchange on the BMD practices of 176 NS-sharing IDUs was evaluated. IDUs were randomly assigned to either 1) Pharmacy Sales Condition, access to NS via legal sales of nonprescription NS; or 2) Needle Exchange Condition, with additional access to NS via an experimental needle exchange program. Repeated measures analysis revealed a main effect of time on BMD, no effect of assignment condition, and no time by assignment interaction. Logistic regression revealed IDUs who traded sex for money or drugs were less likely to practice BMD, and IDUs who reported a reduced number of sex partners were more likely to practice BMD. Future interventions should incorporate behavioral BMD components and address the concerns of those who trade sex for money or drugs.

Adolescent↗

Recurrent use of disposable syringe-needle units in diabetic children.

Fourteen insulin-dependent diabetic children reused their disposable syringe-needle units an average of 6.3 times per needle. Between uses, the needle was wiped with alcohol and stored in the refrigerator. There were no infections reported during the study for an average duration of 94 days. Dullness of the needle was the major reason for changing to a new one. Recurrent use of disposable needles for insulin injections appears safe in children and may be advised. It will help decrease some of the high cost of the daily care of a person with diabetes.

Adolescent↗

A portable syringe driver: design and applications.

Applications of a battery-operated portable syringe driver are reviewed and the Graseby MS16 device is described. Its value in permitting long-term slow infusion of drugs--in preference to intermittent injections--is illustrated by reference to a variety of uses. In size and weight the driver is small enough to permit a patient to wear it even while leading an active life. A custom integrated circuit and a high-efficiency mechanical drive result in such low power consumption that an inexpensive 9V battery will last for up to three months. Applications include heparin infusion, post-operative analgesia, hormone infusions, cancer chemotherapy, domiciliary analgesia in terminal cancer, antibiotics, neonatal infusions, and in human and animal research. One of the most interesting applications has been in the treatment of thalassaemia, extending life expectancy from about 15 years to an indefinite span. The driver incorporates comprehensive safety features.

Equipment and Supplies↗

The syringe nitroxide free radical--Part II.

Some plastic syringes introduce a nitroxide free radical into the fluids they contain. The EPR spectrum shows a triplet with aN = 17.0 +/- 0.1 G in plasma. We report here that this nitroxide/hydroxylamine couple serves as an antioxidant system, whose redox potential appears to be between that of vitamin C and vitamin E. This adventitious antioxidant can alter the course of free radical processes.

Ascorbic Acid↗

Effects of Amsterdam needle and syringe exchange.

The needle and syringe exchange in Amsterdam was initiated in 1984 by the Junky Union. To date, ample data are available to support the role of the needle exchange in facilitating drug injectors to use drugs in a safer way: no increase in drug use could be validated, participants of the exchange schemes were less involved in needle sharing, the supply of large quantities of needles to drug users did not lead to an increase in needle stick accidents by the general public, and, finally, the HIV prevalence among drug injectors has remained stable since 1986, while the incidence of acute hepatitis B has gone down.

Adult↗

Randomized evaluation of 5 French catheters for coronary angiography with or without the CO2 powered Hercules syringe.

To evaluate the CO2 power-assisted hand-held Hercules syringe (Cordis) for diagnostic coronary angiography using 5 French catheters (Judkins number 4 exclusively), 200 consecutive patients (excluding patients with valve disease and prior bypass surgery) were randomized to conventional manual or Hercules injections. The angiography was done through a femoral artery with or without a sheath. Total duration and fluoroscopy time from the end of the ventriculogram to the end of the procedure, quantity of contrast medium required, length of cinefilm, quality of film (good, satisfactory, or bad), streaming, technical ease [scale 1 (easy) to 6 (difficult)], and need for larger catheters were analyzed. Adequate quality angiograms were obtained in 193 patients (97%). Crossover to a larger catheter was required in 7 patients due to difficulty in engaging coronary ostia (right 6, left 1). No significant differences between manual or Hercules injections were seen in total duration of the procedure (12.0 +/- 4.6 versus 12.9 +/- 8.5 min), fluoroscopy time (4.0 +/- 3.1 versus 4.2 +/- 4.8 min), quantity of contrast medium (81 +/- 28 versus 89 +/- 29 ml), and length of the film (1.1 +/- 0.6 versus 1.3 +/- 0.7 min). The conventional method was found to be easier (facility scale: conventional 1.7 +/- 0.5, Hercules 2.3 +/- 1.2, p less than 0.05) because there was significantly less dislodgement of the catheter from the coronary ostia during contrast injections. Five French number 4 Judkins catheters permit adequate diagnostic coronary angiograms in 97% of routine coronary patients.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Sterility testing of disposable syringes and needles marketed in Calcutta.

Presterilized (disposable) syringes and needles were subjected to sterility testing for aerobic cultures. It was found that 56.3% of the samples were contaminated indicating failure of the sterilisation process. The implications of this could be far reaching and is discussed alongwith.

Bacteria, Aerobic↗

Manual cleaning of endoscopes: a comparison study of syringe versus suction methods using the endo-suction cleaning system.

The manual syringe method of cleaning endoscopes involves numerous problems, including cross-infection, contamination, wasted time, and employee safety issues. This article describes the development of an alternative system by a nurse entrepreneur for endoscopic cleaning using a suction method. Scientific findings gathered over four years are presented supporting the efficacy and usefulness of this system, the Endo-Suction Cleaning System, also known as the PSK System.

Costs and Cost Analysis↗

Hemolytic bacteria in water from the dental air-water syringe.

PURPOSE: The purpose of this pilot study was to determine whether aquatic bacteria expressing hemolysis, a classical virulence factor of pathogenic bacteria, could be found in water flowing from the dental air-water syringe (AWS). METHODS: Water samples were collected from the AWS in each of five dental operatories, and a control sample was collected from the cold-water tap in the sink adjacent to one of the dental operatories. Water samples were plated on NWRI agar to enumerate aquatic heterotrophic bacteria and on Tryptic Soy Blood (TSB) agar to enumerate hemolytic bacteria. After incubation, plates were counted to determine total colony-forming units per mL of AWS water. In addition, TSB plates were examined for hemolytic colonies, which were counted if present. RESULTS: AWS water samples contained an average of 9.4 x 10(4) colony-forming units cfu/mL on NWRI agar, and 1.3 x 10(4) cfu/mL on TSB agar. The control sample from the cold-water tap contained 2.5 x 102 and 50 cfu/mL on NWRI and TSB agars, respectively. Four out of five AWS water samples contained hemolytic bacteria, with an average hemolytic count of 3.2 x 10(3) hemolytic cfu/mL on TSB agar. No hemolytic bacteria were detected from tap water. Most hemolytic organisms exhibited alpha-hemolysis although beta-hemolytic colonies were seen. CONCLUSIONS: AWS water can contain hemolytic bacteria--such bacteria express a virulence factor and therefore may be regarded as potential pathogens. According to a Medline search conducted April 23, 2002, this is the first report of hemolytic bacteria from dental unit water.

Bacteria↗

[Improved ambulatory syringe pump system for pain control therapy at home].

UNLABELLED: Terumo Corporation has been developing products for use at home, such as the Cafty pump, based on the opionions and suggestions received through Home-Joint. This time we improved the ambulatory syringe pump TE-361 PCA, so that patients could use it at home. RESULTS: We had patients 49 to 78 years of age use it, continuously, at an injecting speed of 0.1 to 1 ml/h for 5 to 26 days. Patients requiring large volumes of a medicine were offered two or more pumps pre-filled with the medicine. Drug transportation problems were not reported, because of the doctor in charge transported the medicine constantly. Terumo call center did not receive any incidence of trouble, and no trouble was reported in the collected questionnaire. From these facts, it was suggested that this apparatus can be used safely for in-home medical treatment. CONCLUSION: The burden of expenses when two or more pumps are required and installation of the back-up equipment, etc. are problems that should be coped with separately. Moreover, a cooperation system is required in preparation for troubles. We want to establish a system that can be used with confidence by the patients.

Aged↗

Improving needle-point sharpness in prefillable syringes.

Improvement of needle-point sharpness and improved injection comfort for patients remain active areas of research. This article reports on a five-bevel needle for subcutaneous administration with a prefillable syringe, and the results of a clinical trial to verify and validate the bench measure of sharpness.

Adolescent↗

Taxi passenger accidentally stuck by syringe awarded $15,000.

In January 2003, a British Columbia Supreme Court judge awarded $15,000 for mental anguish to a woman who was stuck by a syringe found in the back of a taxicab. In assessing the damages, the Court took into account the woman's possible exposure to HIV and the reasonableness of her belief that she was at risk of seroconverting.

Automobiles↗

Determining serum bicarbonate; a simple syringe titrator and colorimeter.

The use of a tuberculin syringe as a burette has made possible an easy bedside technique for the determination of serum bicarbonate. By combining it with the use of a simple colorimeter, a relatively untrained person can do numerous bicarbonate determinations with a high degree of accuracy. The same technique also lends itself to other colorimetric clinical procedures such as determination of gastric acidity.

Bicarbonates↗