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[Visiting Hungarian medical homepages and portals].

INTRODUCTION: The Internet is a rapidly expanding network that handles miscellaneous data. Everyone or every organisation can join to it. The Internet covers more than 800 millions of documents and it is a hard task to find the relevant and up-to-date information among them. Search engines, portals and virtual catalogues back the retrieval of data. AIM: The aim of this study is to give insight into the presence of Hungarian health institutions on the Internet, and we try to find information about the quality of these Internet resources. SCOPE AND RESULT: Based upon the analysis of 72 Web Pages we drew the conclusion that the Hungarian medical homepages are not prepared well enough to supply content services. There are, however, some examples to very good solutions. The number of medical portals containing exact, up-to-date information is growing continuously.

Humans↗

Herpes zoster ophthalmicus.

BACKGROUND: We examined the literature for the latest information on diagnosis and management of herpes zoster, and compiled a representative database. METHODS: Using search engines and library resources, we reviewed pathology, epidemiology, pathophysiology, differential diagnosis, and management. RESULTS: The varicella zoster virus is a member of the herpes virus family that produces an infection through direct contact with active skin lesions or airborne droplets. The infection resides latent in the trigeminal ganglion until reactivated, often affecting the sensory nerve, skin, eye, and adnexa. CONCLUSION: The varicella zoster virus has the potential to severely disrupt the structures of the eye. Patients less than 50 years of age should be referred for systemic workup to rule out an immunocompromised state. In general, management is often palliative and/or geared toward specific sequelae.

Antiviral Agents↗

Optometry and ophthalmology: the Internet connection--assessing consumer health web sites.

BACKGROUND: The Internet is a major conduit of health information. Consumers frequently rely on it without verifying its validity. The purpose of this study was to assess the accuracy and currency of Internet-based information on the roles and practice of optometrists, which has been found to be misleading, inaccurate, and often outdated. METHODS: Using search engines and ranking directories, 16 popular health Web sites were examined for differentiation between optometry and ophthalmology. Each site's eye care content was reviewed for syndication, definitions, provider directories, linkages to eye organizations, and provider recommendations in treatment of certain conditions. RESULTS: Many Web sites use a syndicated source for their health content and several use Merriam-Webster as their primary dictionary. A majority of sites provided poor definitions for optometry. Most Web sites were biased in recommending ophthalmologists and do not include optometrists as licensed providers in treatment of certain eye diseases. For example, Intelihealth, Aetnaushc, and Noah-Health recommend only ophthalmologists for the treatment of conjunctivitis. CONCLUSIONS: Inaccuracies and misleading information about optometry do exist and undermine the role of optometrists in delivery of eye care. When alerted, several Web sites were receptive to proposed changes. While some efforts have been undertaken to monitor Web sites, the profession must develop a concrete effort to ensure that it is correctly represented on the Internet.

Health Education↗

Good content alone won't bring them back.

Good content is important, but it won't make your site unique. The challenge for medical Webmasters is to find ways to encourage users to go directly to their site rather than to a general search engine. That requires knowing your audiences, and providing features that meet their needs.

Focus Groups↗

Internet resources for hemato-oncologist.

AIM OF THE STUDY: To find out sites of interest for the hemato-oncologist on the internet. METHODOLOGY: Use of search engines like www.google.com and www.yahoo.com and selective identification of the relevant sites by thorough browsing. RESULTS: There are several sites which can be useful to the hemato-oncologist. Some of the sites are related to hematology, hemato-oncology, hemato-pathology, etc. were as some are disease specific e.g., thalassemia, hemophilia, myelodysplastic syndrome. Reliability of the sites have to be judged carefully. CONCLUSIONS: Certain sites provide specific information for selected diseases, and accordingly online browsing is required. Latest articles can be retrieved from Pubmed, Biomednet (www.bmn.com) and few general haematology sites like www.medweb.emory.edu and the cancer-related site www.aacr.org. The benefits of internet include rapid access to relevant information, easy use and also e-consultations.

Hematology↗

Where are the bariatric bypass ads? The answer, my friend, is bloomin' on the Web.

If you look up bariatric, or gastric bypass surgery on the Internet, you'll find 9,000 entries or more, depending on the search engine used. Some of these, but not all, are from hospitals and healthcare systems, most of which have more requests than they can handle. We look at the publicity for bariatric surgery presented by St. Cloud Hospital in St. Cloud, Minn.; Holy Name Hospital, Teaneck, N.J.; Kuakini Medical Center, Honolulu, Hawaii; and Cincinnati Children's Medical Center, Cincinnati, Ohio.

Advertising↗

Benchmarking information needs and use in the Tennessee public health community.

OBJECTIVE: The objective is to provide insight to understanding public health officials' needs and promote access to data repositories and communication tools. METHODS: Survey questions were identified by a focus group with members drawn from the fields of librarianship, public health, and informatics. The resulting comprehensive information needs survey, organized in five distinct broad categories, was distributed to 775 Tennessee public health workers from ninety-five counties in 1999 as part of the National Library of Medicine-funded Partners in Information Access contract. RESULTS: The assessment pooled responses from 571 public health workers (73% return rate) representing seventy-two of ninety-five counties (53.4% urban and 46.6% rural) about their information-seeking behaviors, frequency of resources used, computer skills, and level of Internet access. Sixty-four percent of urban and 43% of rural respondents had email access at work and more than 50% of both urban and rural respondents had email at home (N = 289). Approximately 70% of urban and 78% of rural public health officials never or seldom used or needed the Centers for Disease Control (CDC) Website. Frequency data pooled from eleven job categories representing a subgroup of 232 health care professionals showed 72% never or seldom used or needed MEDLINE. Electronic resources used daily or weekly were email, Internet search engines, internal databases and mailing lists, and the Tennessee Department of Health Website. CONCLUSIONS: While, due to the small sample size, data cannot be generalized to the larger population, a clear trend of significant barriers to computer and Internet access can be identified across the public health community. This contributes to an overall limited use of existing electronic resources that inhibits evidence-based practice.

Attitude to Computers↗

Improvement of automatic in-gel digestion by in situ alkylation of proteins.

We have recently improved the automation of an in-gel digestion system, DigestPro 96, using in situ alkylation of proteins with acrylamide, conducted during one-dimensional (ID) SDS-PAGE. The improved method included the processes of destaining, dehydration, trypsin digestion, and extraction but excluded the reduction and alkylation steps following staining of proteins with CBB. The extracted peptide mixtures were directly loaded onto a micro C18 LC column of the mass spectrometer. The resultant spectra were processed with "Mascot" search engine to estimate the sequence coverage of the bovine serum albumin (BSA). The original method, designed for Laemmli ID SDS gel applications, consisted of reduction and post-alkylation with iodoacetamide, which produced carboxyamidemethyl (CAM; -S-CH2CONH2) derivatives. The original method also included a desalting step essential for mass spectrometry, especially matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. We compared the original and improved methods using BSA (3 pmol loaded to the gel, one third of digested peptide mixture injected into LC-MS). The original method yielded both CAM and propionicamide (PAM;-S-CH2CH2CONH2) derivatives. The source of PAM derivatives is the unpolymerized acrylamide formed during electrophoresis. The sequence coverage of CAM derivatives of BSA by the original method was 10% with desalting and 19% without desalting. The sequence coverage of PAM derivative by the improved method was 32%. Our results clearly show the advantage of our improved automated in-gel digestion method for in situ PAM alkylated protein with respect to peptide recovery, compared with the original method with CAM post-alkylation.

Alkylation↗

Internet use by patients in orthopaedic surgery.

This study evaluated Internet use among orthopaedic patients in a private practice general orthopaedic setting. Of 201 participants, 45% had used the Internet either personally or thru a surrogate to search for information about their orthopaedic condition. Utilization of the Internet was significantly higher than that reported for a community orthopaedic practice surveyed in 1998, suggesting that utilization by orthopaedic patient populations mirrors the increasing societal use for health information. Most users in this study employed multiple search strategies, including using search engines and sites recommended by others. The majority of users found medical information on Internet sites to be useful and accurate. The number one choice for reconciling conflicting information was to ask a physician or a nurse. Most users and non-users reported that they would recommend the Internet to others as a source for medical information. We recommend several strategies for orthopaedic surgeons to stay abreast of these changes and to utilize Internet Patient education resources to their own advantage.

Adolescent↗

The National Eye Institute of The National Institutes of Health: its history and impact on clinical eye care.

BACKGROUND: Research supported by the National Eye Institute (NEI) of the National Institutes of Health (NIH) has contributed to the visual well being of the world. Pertinent citations from the literature were compiled to produce a clinical database reviewing major studies of the NEI and their outcomes. METHODS: Using Internet search engines and library resources, clinical NEI studies were reviewed. Their purpose, description, outcome and clinical importance are summarized. RESULTS: The results of major clinical NEI research are presented and included are the current modalities of treatment for each disease studied. CONCLUSION: Each NEI study yielded results upon which current scientific guidelines for the treatment or prevention of ocular disease are based.

Biomedical Research↗

Efficient hemodynamic event detection utilizing relational databases and wavelet analysis.

Development of a temporal query framework for time-oriented medical databases has hitherto been a challenging problem. We describe a novel method for the detection of hemodynamic events in multiparameter trends utilizing wavelet coefficients in a MySQL relational database. Storage of the wavelet coefficients allowed for a compact representation of the trends, and provided robust descriptors for the dynamics of the parameter time series. A data model was developed to allow for simplified queries along several dimensions and time scales. Of particular importance, the data model and wavelet framework allowed for queries to be processed with minimal table-join operations. A web-based search engine was developed to allow for user-defined queries. Typical queries required between 0.01 and 0.02 seconds, with at least two orders of magnitude improvement in speed over conventional queries. This powerful and innovative structure will facilitate research on large-scale time-oriented medical databases.

Algorithms↗

The unrealized potential of prenatal care. A population health approach.

To review the scientific evidence behind the traditional view that prenatal care improves pregnancy outcomes. The literature published in English between 1965 and 2002 was searched for relevant studies and opinions on prenatal care outcomes. As search engine we used the MEDLINE bibliographic database, employing a combination of keywords, including pregnancy, prenatal care and outcomes. Editorials, proceedings of meetings and reviews, were included in the analysis. This review was not intended to be a systematic or exhaustive review of the literature on prenatal care. The significant heterogeneity of the retrieved papers made any aggregation impossible. In each of the reviewed studies we assessed the methodologic aspects and validity of conclusions, using established criteria for the evaluation of prenatal interventions. Our processing of editorials and other personal opinions was conducted with the intention to draw the line between statements based on scientific evidence and speculative, emotional or traditional concepts. Outcomes research related to prenatal care is marred by methodologic flaws and conceptual problems. While traditional prenatal protocols are based on an individual-centered medical care system, the outcomes are measured using population-based parameters. Interventions capable of improving maternal and neonatal outcomes at the population level are more likely to be social and economic rather than health interventions case by case.

Community Health Planning↗

Machine translation-supported cross-language information retrieval for a consumer health resource.

The U.S. National Institutes of Health, through its National Library of Medicine, developed ClinicalTrials.gov to provide the public with easy access to information on clinical trials on a wide range of conditions or diseases. Only English language information retrieval is currently supported. Given the growing number of Spanish speakers in the U.S. and their increasing use of the Web, we anticipate a significant increase in Spanish-speaking users. This study compares the effectiveness of two common cross-language information retrieval methods using machine translation, query translation versus document translation, using a subset of genuine user queries from ClinicalTrials.gov. Preliminary results conducted with the ClinicalTrials.gov search engine show that in our environment, query translation is statistically significantly better than document translation. We discuss possible reasons for this result and we conclude with suggestions for future work.

Clinical Trials as Topic↗

Evaluation of web accessibility of consumer health information websites.

The objectives of the study are to construct a comprehensive framework for web accessibility evaluation, to evaluate the current status of web accessibility of consumer health information websites and to investigate the relationship between web accessibility and property of the websites. We selected 108 consumer health information websites from the directory service of a Web search engine. We used Web accessibility specifications to construct a framework for the measurement of Web Accessibility Barriers (WAB) of website. We found that none of the websites is completely accessible to people with disabilities, but governmental and educational health information websites exhibit better performance on web accessibility than other categories of websites. We also found that the correlation between the WAB score and the popularity of a website is statistically significant.

Persons with Disabilities↗

A technique to improve the spelling suggestion rank in medical queries.

Correct spelling is crucial for online search engines to function well, and health information is highly sought after online. We propose a technique for increasing the effectiveness of spell-checking tools for use with medical queries. Our results show a marked improvement in the ranking of the correct term within the suggestion list returned by the spelling correction tool, as well as a lessening of the drawbacks associated with using larger dictionaries.

Dictionaries, Medical as Topic↗

Implementation and evaluation of an virtual intelligent agent.

Reference librarians at the National Library of Medicine answer over 100,000 client questions annually. Although many answers are the NLM Web, clients may have difficulty finding them. Using intelligent virtual agent software, the NLM launched Cosmo, the Customer Service Owl (http://wwwns.nlm.nih.gov/). Cosmo uses natural language pattern matching to answer common questions. Early evaluation shows Cosmo can answer 25% of questions asked, but some users mistake the service for chat reference or a search engine.

Artificial Intelligence↗

Publication, citations, and impact factors of leading investigators in critical care medicine.

INTRODUCTION: Critical care medicine research is reported in major medical journals that can be accessed via computerized search engines such as PubMed (National Library of Medicine) or Web of Science (Thomson ISI [Institute for Scientific Information]). The crediting of report citations to specific journals or individuals is a rapidly developing and highly controversial evaluative process. METHODS: We conducted a citation analysis to measure the research and publication accomplishments of critical care medicine investigators, by tallying their numbers of published reports and numbers of citations to their reports. Major investigators were identified from the author indexes of major critical care medicine publications. From the Web of Science the number of publications and citations of their works were determined for 224 investigators for the period 1997 through August 2003. We calculated the individual researcher's "impact factor" by dividing the number of citations (made by other researchers to a given researcher's reports) by the number of articles that researcher had published. To estimate which countries are producing the most research on mechanical ventilation, we studied the abstract books from the 2001, 2002, and 2003 American Thoracic Society annual international conferences and tallied the number of posters (pertaining to mechanical ventilation) from the various countries. We then calculated a "country factor" as the number of posters per million population of the source country. RESULTS: We considered 44, 576 citations in 3,755 publications. Using criteria selected to recognize original works, J L Vincent published the greatest number of reports (129). M A Matthay received the most citations (2,056). G U Meduri had the highest impact factor (25.32). There was a balance between the number of leading investigators from Europe and North America. Relative to its population size, Canada warrants leadership acknowledgement in critical care medicine, considering its number of leading investigators and poster presentations. CONCLUSIONS: From criteria selected to attribute original work to specific authors we identified 20 leading critical care medicine investigators, as measured by number of publications, citations, and impact factors. We also report a country factor based on posters (on mechanical ventilation) presented at the 2001-2003 international conferences of the American Thoracic Society.

Authorship↗

Current situation of human diphyllobothriasis in Europe.

Diphyllobothriasis, a parasitosis caused by the flatworm Diphyllobothrium latum, is contracted by consuming raw or undercooked freshwater fish. The aim of this study was to evaluate the situation of this parasitosis during the past 20 years in Europe through the analysis of databases and search engines (Medline, Cabi Helminthological abstracts,Yahoo, Google), and through a questionnaire sent to a network of European parasitologists and to microbiological laboratories located on the shores of the large Alpine lakes. This study has shown that several dozen cases have been reported each year in Finland and Sweden, that there have been numerous cases in the French or Italian speaking areas of subalpine lakes, and that sporadic cases only have been observed in Austria, Spain, Greece, Romania, Poland and Norway. Over 30 cases have been identified on the Swiss shores of Lake Maggiore since 1990, and 70 cases on the Swiss and French shores of Lake Leman between 1993 and 2002. Eight to 12% of perch fillets from Lake Leman and 7.8 % of perch from Lake Maggiore were infested with larvae. Contamination sources include marinated fish fillets in northern Europe, 'carpaccio di persico' in northern Italy, and perch and charr consumed raw or undercooked around Lake Leman. Factors allowing the continuation of the parasitic cycle include the continued dumping of wastewater into lakes, yachtsmen who also fish, and a possible animal reservoir.

Animals↗