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The Contact Lens Impact on Quality of Life (CLIQ) Questionnaire: development and validation.

PURPOSE: To develop and validate a questionnaire for the measurement of the impact of contact lenses on quality of life (QoL): The Contact Lens Impact on Quality of Life (CLIQ) Questionnaire. METHODS: The questionnaire was developed and validated using conventional methods and Rasch analysis to assure content validity, repeatability, construct validity, and low respondent burden. Item identification and selection (647 items) were performed with an extensive literature review, professional advice, and lay focus groups. Item reduction used focus groups and data obtained from 161 subjects completing a 90-item pilot questionnaire. Validity and reliability, from data of 128 additional subjects, were assessed using Rasch analysis, intraclass correlation coefficient, and Bland-Altman limits of agreement. RESULTS: A 28-item CLIQ Questionnaire was developed and shown to have good validity and reliability by Rasch analysis statistics: real person separation, 2.02; model person separation, 2.17; reliability, 0.80; root mean square measurement error, 2.73; mean square+/-SD infit, 1.01+/-0.18; outfit, 1.01+/-0.19. The items (mean score, 49.8+/-4.9) were well targeted to the subjects (mean score, 51.2+/-6.2) with a mean difference of 1.35 (scale range, 0-100) units. Test-retest intraclass correlation coefficient (0.86) and coefficient of repeatability (+/-8.00 units) demonstrated good repeatability. CONCLUSIONS: Rasch analysis and standard psychometric analyses demonstrated that the 28-item CLIQ Questionnaire is a valid and reliable measure of QoL in contact lens wearers. A scoring algorithm is provided for CLIQ Questionnaire users to convert raw scores into the Rasch analysis-derived linear person measures.

Adolescent↗

Development of the Children's Health Ratings Scale.

Following pilot testing, the 17-item Children's Health Ratings Scale was group administered to approximately 1,200 fourth- through sixth-grade students. The internal consistency reliability, concurrent validity, and construct validity of the scale were examined utilizing various statistical methods, including calculation of the alpha coefficient, factor analysis, and other correlational techniques. The scale was found to be reliable with an alpha coefficient of .83. Concurrent validity was supported by the finding that higher scale scores were associated with higher ratings on a single, general health item and with lower ratings on single items concerning pain, health worry, and the presence of sickness. Correlations between scores on the Children's Health Ratings Scale and sex, grade level, and a measure of response bias were of low magnitude and presented no serious threat to instrument validity. Five factors were identified for interpretation during factor analysis. A post hoc validity study compared the mean scale scores of a group of asthmatic children and a subsample from the scale development study. Suggestions for further study are presented.

Attitude to Health↗

The ECOS-16 questionnaire for the evaluation of health related quality of life in post-menopausal women with osteoporosis.

BACKGROUND: The aim of this study is to validate the questionnaire ECOS-16 (Assessment of health related quality of life in osteoporosis) for the evaluation of health related quality of life (HRQoL) in post-menopausal women with osteoporosis. METHODS: An observational, prospective and multi-centre study was carried out among post-menopausal women with osteoporosis in primary care centres and hospital outpatient clinics. All patients attended 2 visits: at baseline and at 6 months. In addition, the subgroup of outpatients attended another visit a month after the baseline to assess the test-retest reliability. The psychometric properties of the questionnaire were evaluated in terms of feasibility, validity (content validity and construct validity) and internal consistency in baseline, and in terms of test-retest reliability and responsiveness to change in visit at month and visit at 6 months, respectively. In all visits, ECOS-16, EUROQoL-5D (EQ-5D) and four 7-point items about health status (general health status, back pain, limitation in daily activities and emotional status) were administered, whereas only outpatients were given MINI-OQLQ (Mini Osteoporosis Quality of Life Questionnaire), besides all clinical variables; and sociodemographic variables at baseline. RESULTS: 316 women were consecutively included, 212 from primary care centres and 104 from hospital outpatient clinics. Feasibility: 94.3% of patients answered all items of the questionnaire. The mean administration time was 12.3 minutes. VALIDITY: factor analysis suggested that the questionnaire was unidimensional. In the multivariate analysis, patients with vertebral fractures, co-morbidity and a lower education level showed to have worse HRQoL. Moderate to high correlations were found between the ECOS-16 score and the other health status questionnaires (0.47-0.82). Reliability: internal consistency (Cronbach's alpha) was 0.92 and test-retest reliability (ICC) was 0.80. Responsiveness to change: ECOS-16 scores increased according to change perceived by the patient, as well as the effect size (ranges between 1.35 to 0.43), the greater the perception of change in patients' general health status, the greater the changes in patients' scores. The Minimal Clinically Important Difference (MCID) suggested a change of 0.5 points in the ECOS-16 score, representing the least improvement in general health status due to their osteoporosis: "slightly better". CONCLUSION: ECOS-16 has been proven preliminarily to have good psychometric properties, so that it can be potentially a useful tool to evaluate HRQoL of post-menopausal women with osteoporosis in research and routine clinical practice.

Aged↗

Validation of the functional assessment of multiple sclerosis quality of life instrument.

Based on scientific literature and interviews with clinicians and patients, we developed a quality of life instrument for use with people with MS called the Functional Assessment of Multiple Sclerosis (FAMS). The initial item pool consisted of 88 questions: 28 from the general version of the Functional Assessment of Cancer Therapy quality of life instrument, plus 60 generated by patients, providers, and literature review. The validation samples comprised a mail survey cohort (N = 377) and a clinical cohort (N = 56). Both cohorts provides evidence for internal consistency of the derived subscales, test-retest reliability, content validity, concurrent validity, and construct validity. Principal components and Rasch measurement model analyses were applied sequentially to survey sample data, reducing test length to 44 questions, divided into six subscales: mobility, symptoms, emotional well-being (depression), general contentment, thinking/fatigue, and family/social well-being. Fifteen initially rejected questions were added back as miscellaneous (unscored) questions for their potential clinical and empirical value. The mobility subscale was strongly predictive of the Kurtzke Extended Disability Status Scale and the Scripps Neurologic Rating Scales. The other five subscales were not, indicating they measure aspects of patient quality of life not captured by the neurologic exam. The final 59-item English language instrument (FAMS version 2) is available for inclusion in clinical trials and clinical practice.

Adult↗

Psychometric evaluation of a new sensory scale in immune-mediated polyneuropathies. Inflammatory Neuropathy Cause and Treatment (INCAT) Group.

OBJECTIVE: To perform a psychometric evaluation of the inflammatory neuropathy cause and treatment (INCAT) sensory sumscore (ISS) in sensory-motor immune-mediated polyneuropathies. This new sensory scale was evaluated to strive for uniformity in assessing sensory deficit in these disorders. METHODS: The ISS comprises vibration and pinprick sense plus a two-point discrimination value and ranges from 0 (normal sensation) to 20 (maximum sensory deficit). Before its clinical use, a panel of expert neurologists concluded that the ISS has face and content validity. The construct validity of the ISS was investigated by correlation and regression studies with additional scales (Nine-Hole Peg Test, 10-Meter Walking Test, a disability sumscore). All scales were applied in 113 patients with a stable neurologic condition (83 patients who experienced Guillain-Barre syndrome [GBS] in the past, 22 with chronic inflammatory demyelinating polyneuropathy [CIDP], 8 patients with a monoclonal gammopathy associated polyneuropathy), and 10 patients with recently diagnosed GBS or CIDP with changing clinical conditions. Reliability of the ISS was evaluated in the stable patients. Its responsiveness was investigated in the patients examined longitudinally. RESULTS: A moderate to good validity was obtained for the ISS (stable group: r = 0.38 to 0.56, p < or = 0.006; longitudinal group: R = 0.60 to 0.82, p < or = 0.007, except for the association with the 10-Meter Walking Test [p = 0.08]). Acceptable internal consistency, and inter- and intraobserver reliability were demonstrated for the ISS (alpha = 0.68 to 0.87; R = 0.85 to 0.89, p < 0.0001). Standardized response mean scores for the ISS were high (> or =0.8), indicating good responsiveness. CONCLUSIONS: All psychometric requirements are provided for the the inflammatory neuropathy cause and treatment sensory sumscore. The use of this scale is therefore suggested for bedside evaluation of sensory deficit in the individual patient with a sensory-motor immune-mediated polyneuropathy as well as in clinical trials.

Adolescent↗

The physical activity recall assessment for people with spinal cord injury: validity.

PURPOSE: This study examined the construct validity of the physical activity recall assessment for people with spinal cord injury (PARA-SCI). METHODS: First, to assess convergent validity, relationships between PARA-SCI scores and measures of aerobic fitness and muscular strength were examined among 73 men and women with SCI. Second, extreme groups analyses were conducted. PARA-SCI scores from 158 people with SCI were compared between groups differing on demographic, disability, and behavioral characteristics. RESULTS: Scores from the leisure time physical activity (LTPA) and cumulative activity PARA-SCI categories correlated positively with parameters of aerobic fitness and muscular strength. Scores from the lifestyle activity PARA-SCI category were not consistently associated with fitness parameters. LTPA category scores could differentiate between groups differing by age, sex, gym or sports team membership, and frequency of participation in LTPA. Lifestyle and cumulative activity scores were unable to distinguish between most groups. CONCLUSION: The convergent validity study provided evidence of validity for the PARA-SCI LTPA and cumulative activity categories. The extreme groups analyses provided further evidence of the validity of the LTPA category by demonstrating differences in extreme groups. Together, these findings contribute to the accumulating evidence of the construct validity of the PARA-SCI LTPA category and its utility for assessing LTPA among individuals with SCI. These results also highlight measurement constraints of the lifestyle activity and cumulative activity categories.

Adult↗

Validity and reliability of the Leisure Assessment Inventory.

The validity and reliability of the Leisure Assessment Inventory, a tool developed to measure leisure behavior as it applies to adults with mental retardation, was examined. Leisure behavior was assessed using four indexes: Leisure Activity Participation, Leisure Preference, Leisure Interest, and Leisure Constraints. The inventory was administered to 92 adults, ages 30 and older, with mild to moderate mental retardation. Two indexes (Leisure Activity Participation and Leisure Interest) demonstrated higher reliability from test to retest whereas the remaining two (Leisure Preference and Leisure Constraints) showed only moderate consistency. Overall findings provide evidence of the inventory's stability, consistency, convergent and discriminant validity, and construct validity.

Adult↗

A psychometric assessment of the Children of Alcoholics Screening Test (CAST).

OBJECTIVE: Children of alcoholics have been identified as an at-risk population for a number of physical, emotional and behavioral problems. Therefore, accurate identification of this potential client group is important for both prevention and intervention programming. The current study investigated the psychometric properties of the Children of Alcoholics Screening Test (CAST), which was developed as an assessment tool for identifying latency-age, adolescent and adult children of alcoholics. METHOD: Respondents were recruited through the use of nominational sampling methods for participation in this cross-sectional study. The study sample was composed of 65 male and 149 female respondents, including both adult children of alcoholics (ACOAs) and adults reared in non-substance-abusing homes (non-ACOAs). Both ACOA (n = 140) and non-ACOA (n = 74) groups included clinical and nonclinical subjects. Respondents completed a mailed, self-report survey that included the CAST, five other standardized instruments measuring family and personal functioning, and sociodemographic questions. RESULTS: Study findings indicated that the CAST is unidimensional, possesses excellent reliability (alpha = .98) and has a low standard error of measurement. Support was also shown for several types of measurement validity, including discrimination validity, factorial validity and construct validity. CONCLUSIONS: Data from the current study support use of the CAST as a reliable and valid instrument that may be employed in both research and clinical practice.

Adult↗

A review of health-related workplace productivity loss instruments.

The objective of this review was to identify health-related workplace productivity loss survey instruments, with particular emphasis on those that capture a metric suitable for direct translation into a monetary figure. A literature search using Medline, HealthSTAR, PsycINFO and Econlit databases between 1966 and 2002, and a telephone-administered survey of business leaders and researchers, were conducted to identify health-related workplace productivity measurement survey instruments. This review was conducted from the societal perspective. Each identified instrument was reviewed for the following: (i). reliability; (ii). content validity; (iii). construct validity; (iv). criterion validity; (v). productivity metric(s); (vi). instrument scoring technique; (vii). suitability for direct translation into a monetary figure; (viii). number of items; (ix). mode(s) of administration; and (x). disease state(s) in which it had been tested. Reliability and validity testing have been performed for 8 of the 11 identified surveys. Of the 11 instruments identified, six captured metrics that are suitable for direct translation into a monetary figure. Of those six, one instrument measured absenteeism, while the other five measured both absenteeism and presenteeism. All of the identified instruments except for one were available as paper, self-administered questionnaires and many were available in languages other than English. This review provides a comprehensive overview of the published, peer-reviewed survey instruments available to measure health-related workplace productivity loss. As the field of productivity measurement matures, tools may be developed that will allow researchers to accurately calculate lost productivity costs when performing cost-effectiveness and cost-benefit analyses. Using data captured by these instruments, society and healthcare decision makers will be able to make better informed decisions concerning the value of the medications, disease management and health promotion programmes that individuals receive.

Absenteeism↗

Testing psychometric properties of the standard Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire 30 (EORTC QLQ-C30).

BACKGROUND: Because cancer is now the first and second leading causes of death in both of urban and suburban area in China, there are increasing demands for measurement tools to assess quality of life in Chinese cancer patients. The objective of this study was to evaluate the psychometric properties of the standard Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire 30 (EORTC QLQ-C30, version 3.0). METHODS: The questionnaire was administered before, during, and after treatment of 143 patients with breast, gynecological, or lung cancer in six hospitals in China. RESULTS: Cronbach's alpha coefficients for multi-item scales were greater than 0.70 before and during treatment, except for the cognitive functioning scale. Multitrait scaling analysis showed that most of the item-scale correlation coefficients met the standards of convergent and discriminant validity. All scales and items exhibited good reproducibility, criterion-related validity, and construct validity. Score changes over time were observed in the following scales: physical, role, and social functioning; global quality of life; fatigue; nausea/vomiting. Score changes were also observed in the appetite loss item. CONCLUSION: The standard Chinese version of the EORTC QLQ-C30 is overall a valid instrument to assess the quality of life of Chinese cancer patients.

Adult↗

The development of the "Cantonese receptive vocabulary test' for children aged 2-6 in Hong Kong.

The study aims to develop a Cantonese receptive vocabulary test to assess 2-6-year-old children in Hong Kong. The test consists of 100 test items. Each target item is accompanied by a phonological distractor, a semantic distractor and an unrelated distractor. A sample of 609 normal children from four Maternal and Child Health Centres and nine kindergartens was selected. The results show that there is a significant effect of age on the correct score. ANOVA was performed to look at the age effect on each distractor individually. It was found that the scores of the three distractors decrease in their own patterns as age increases. With strong content validity, strong construct validity and high correlation coefficients in the split-half reliability, this test could be used as a reliable measurement for the Cantonese-speaking population in Hong Kong.

Analysis of Variance↗

[Validation of interviewer administration of the Short Form 36 Health Survey, and comparisons of health-related quality of life between community-dwelling and institutionalized elderly people].

The Short Form 36 Health Survey (SF-36) is a questionnaire that is widely used to measure health-related quality of life. Because self-administered questionnaires may not be appropriate for seriously ill or elderly people, we administered the SF-36 to institutionalized elderly people by face-to-face interviews, and tested its reliability and validity. We also compared the SF 36 score of those subjects with the scores of community-dwelling elderly people. We studied 117 people aged 65 or over who were living in residential facilities on Sado island and 62 randomly sampled elderly people who were living in the community. The SF-36 scores of the institutionalized subjects had acceptable ceiling and floor effects, and their internal consistency, concurrent validity, and construct validity were high. The only exceptions were the scores of the "vitality" subscale. Adjusted mean scores on four subscales were higher among the institutionalized subjects than among those living in the community: role limitation due to physical condition, role limitation due to emotional condition, social functioning, and bodily pain. The two groups did not differ with regard to scores on the "mental health" scale, the "vitality" scale, or the "general health perception" scale. We conclude that the SF-36 can be useful for measuring health-related quality of life among institutionalized elderly people, if it is administered in face-to-face interviews.

Activities of Daily Living↗

Evaluating an assessment scale of irrational beliefs for people with mental health problems.

In this paper, Douglas MacInnes examines the validity of a measure of irrational beliefs, the Shortened General Attitude and Belief Scale (SGABS). He examines the overall correlation between the various subscales of the measure, the criterion validity and construct validly of the instrument, as well as internal consistency. Results show that the measure had good validity and was a useful measure of irrational beliefs for clinicians and researchers working in the area of cognitive behaviour therapy.

Adolescent↗

Evaluating clinical competence of physical therapy students. Part 2: assessing the reliability, validity and usability of a new instrument.

This study was conducted to establish the reliablity and validity of an instrument designed to evaluate the clinical competence of physical therapy (PT) students. A criterion-referenced evaluation instrument--the Evaluation of Clinical Competence (ECC)--was developed by the investigator according to the procedures recommended in the measurement literature. This behaviourally-anchored, four-point rating scale was tested on two groups of PT students from the University of Alberta, Edmonton, Canada. In order to obtain data by which to analyze and revise the ECC, the ECC was administered to fourth-year PT students (n = 29) during their clinical placement in November 1982, according to specified instructions. The revised ECC was administered to third-year (n = 23) and fourth-year PT students (n = 25) during their clinical placements in February and March of 1983. The same instructions were followed in order to collect the necessary data to establish inter-rater reliability, concurrent validity, and construct validity of the ECC. The results of the study suggest that the ECC is a fairly reliable, valid, and practical instrument with which to assess the clinical competence of PT students.

Clinical Competence↗

Reliability and validity of a breastfeeding attitudes instrument for nursing staff.

An instrument was designed and validated with the purpose of identifying attitudes towards breastfeeding among nursing professionals. The preliminary instrument contained 19 items which were submitted to experts in the field of human lactation and breastfeeding for content validity. The construct validity was measured through factor analysis and matrix correlation. Four factors were identified in the analysis. Overall internal consistency of the instrument was 0.83, with a subscale's range fluctuating from 0.64 to 0.73. The instrument is valid and reliable, and it is the first of its nature in Puerto Rico.

Adult↗

Estimation of in-vivo neurotransmitter release by brain microdialysis: the issue of validity.

Although microdialysis is commonly understood as a method of sampling low molecular weight compounds in the extracellular compartment of tissues, this definition appears insufficient to specifically describe brain microdialysis of neurotransmitters. In fact, transmitter overflow from the brain into dialysates is critically dependent upon the composition of the perfusing Ringer. Therefore, the dialysing Ringer not only recovers the transmitter from the extracellular brain fluid but is a main determinant of its in-vivo release. Two types of brain microdialysis are distinguished: quantitative micro-dialysis and conventional microdialysis. Quantitative microdialysis provides an estimate of neurotransmitter concentrations in the extracellular fluid in contact with the probe. However, this information might poorly reflect the kinetics of neurotransmitter release in vivo. Conventional microdialysis involves perfusion at a constant rate with a transmitter-free Ringer, resulting in the formation of a steep neurotransmitter concentration gradient extending from the Ringer into the extracellular fluid. This artificial gradient might be critical for the ability of conventional microdialysis to detect and resolve phasic changes in neurotransmitter release taking place in the implanted area. On the basis of these characteristics, conventional microdialysis of neurotransmitters can be conceptualized as a model of the in-vivo release of neurotransmitters in the brain. As such, the criteria of face-validity, construct-validity and predictive-validity should be applied to select the most appropriate experimental conditions for estimating neurotransmitter release in specific brain areas in relation to behaviour.

Journal Article↗

Development of the Muscle Dysmorphia Inventory (MDI).

AIM: The development of the 6-factor, 27-item Muscle Dysmorphia Inventory (MDI) was based on Lantz et al. proposed model of characteristics associated with Muscle Dysmorphia. METHODS EXPERIMENTAL DESIGN: quantitative procedures including item-to-total correlations, exploratory and confirmatory factor analyses, and structure equation modeling confirmed the construct validity of the scale. Convergent validity was also tested. SETTING: bodybuilding and powerlifting competition venues, weight training facilities, and university athletic venues. PARTICIPANTS: the 1(st) study consisted of 77 experienced male free weight lifters. The 2(nd) study consisted of 156 male non-competitive bodybuilders and weight lifters and 168 elite level powerlifters and bodybuilders. The 3(rd) study consisted of 151 male and female bodybuilders and weight lifters. MEASURES: each participant completed demographic information, the MDI, Drive for Thinness subscale of the Eating Disorder Inventory, and the Training Dependency subscale of the Bodybuilding Dependence Scale. RESULTS: Reliability estimates (Cronbach's a) ranged from 0.72 to 0.94. Factor loadings in all 3 studies supported the 6-factor structure (size/symmetry, supplement use, exercise dependence, pharmacological use, dietary behavior, and physique protection). Much of the scale validation was focused on construct validity, however, correlations with the MDI's subscales and the Training Dependency subscale of the Bodybuilding Dependence Scale and the Drive for Thinness subscale of the Eating Disorder Inventory provided evidence of convergent validity also. CONCLUSIONS: From these preliminary results, the MDI appears to contribute to the identification of a newly formed disorder by offering a multi-dimensional measure of factors related to Muscle Dysmorphia.

Adult↗