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Vocal production mechanisms in the budgerigar (Melopsittacus undulatus): the presence and implications of amplitude modulation.

In this paper acoustic evidence is presented for the presence of amplitude modulation in budgerigar (Melopsittacus undulatus) contact calls and learned English vocalizations. Previously, acoustic analyses of budgerigar vocalizations have consisted solely of visual inspection of spectrograms or power spectra (derived from Fourier transformation). Such analyses have led researchers to conclude that budgerigar vocalizations are primarily frequency-modulated, harmonic vocalizations. Although budgerigar calls have been shown to contain regions that are modulated in amplitude, the implications of this fact have been largely ignored. Amplitude modulation, the nonlinear interaction between two separate signals that results in the creation of new, heterodyne (sum and difference) frequencies, can produce a very complex Fourier spectrum that may resemble that produced by a harmonic vocalization. In this paper, the acoustic principles necessary for identifying amplitude modulation present in signals are outlined, and followed by data demonstrating that amplitude modulation is a prominent feature not only of natural budgerigar contact calls, but also of their learned English vocalizations. It is illustrated how analyzing a vocalization that contains amplitude modulation as if it were harmonic can result in misinterpretations of the acoustic and physical properties of the sound and sound source. The implications of amplitude modulation for studies of the ontogenetic, physical, and neural basis of budgerigar vocalizations are discussed, and a potential model for how the budgerigar syrinx may function to produce amplitude modulation is proposed.

Animals↗

Nonlinear analysis of the EEG of schizophrenics with optimal embedding dimension.

We estimated the correlation dimensions of EEGs in patients with schizophrenia to investigate the dynamical properties underlying the EEG. We employed a new method, proposed by Kennel et al. (Kennel MB, Brown R, Abarbanel HDI. Determining embedding dimension for phase-space reconstruction using a geometrical construction. Phys Rev A 1992;45:3403-11), to calculate the correlation dimension D2. That method determined the proper minimum embedding dimension by looking at the behaviour of nearest neighbours under a change in the embedding dimension d from d to d + 1. We demonstrated that for limited noisy data, our algorithm was strikingly faster and more accurate than previous ones. We estimated the D2 of EEGs from 16 channels in patients with schizophrenia according to DSM-IV whereas previous studies, which estimated chaoticity of EEG in schizophrenia, recorded EEG only in a limited number of channels. Schizophrenic patients had a lower correlation dimension in the left inferior frontal and anterior temporal regions compared with controls. Our finding of decreased left frontal and temporal chaotic activity in schizophrenics is in line with the findings of a hypofrontality and hypotemporality reported in previous clinical studies such as EEG, blood flow, brain MRI and positron emission tomography studies in schizophrenia. This result suggests that chaos analysis may be a useful tool in analysing EEG data to explore the brain mechanism of schizophrenia.

Adult↗

Nonmanipulative determination of plant community dynamics.

Knowledge of the strengths of interactions between species in plant communities is of fundamental importance to our understanding of how communities are structured, although they are notoriously difficult to quantify. Techniques have recently been developed that allow the detailed enumeration of the strength of interactions between plant species within unmanipulated multispecies communities. Nonlinear regression analysis is used to fit competition models to long-term census data using natural variations in plant densities in lieu of manipulation. The models generated have been used to infer the intensity and importance of interactions as well as to analyse the effects of spatial and temporal variability. Theoretical work has begun to look at how different techniques for measuring competition perform in a range of systems, highlighting the importance of spatial scale. The lessons learned from applying these methods will enable improved estimation of the strength of competition in natural communities.

Journal Article↗

Interference effects and phase sensitivity in hearing.

This paper reviews interference effects in the auditory system, particularly effects occurring in the outer ear and the inner ear (cochlea). Sounds enter the ear canal both directly and after reflections from the pinna. This results in complex spectral patterns, which vary systematically with the direction of incidence of the sound source relative to the head. Evidence is described indicating that these spectral patterns are used in the localization of sounds in space. The cochlea behaves like a limited-resolution frequency analyser. When the components of a complex sound are closely spaced in frequency, they can interfere on the basilar membrane (BM) within the cochlea. Interference effects on the BM are complex, as they are influenced by a physiologically active mechanism which introduces strong nonlinearities, including level-dependent amplification. Interference effects on the BM play a role in many aspects of auditory perception, including the perception of consonance and dissonance, the perception of pitch, the perception of changes in phase, and the perception of timbre. Interference effects in the cochlea may also play a role in producing the spectral regularity observed in sounds reflected from the ear (otoacoustic emissions).

Animals↗

Anisotropic mechanical properties of tissue components in human atherosclerotic plaques.

Knowledge of the biomechanical properties of human atherosclerotic plaques is of essential importance for developing more insights in the pathophysiology of the cardiovascular system and for better predicting the outcome of interventional treatments such as balloon angioplasty. Available data are mainly based on uniaxial tests, and most of the studies investigate the mechanical response of fibrous plaque caps only. However, stress distributions during, for example, balloon angioplasty are strongly influenced by all components of atherosclerotic lesions. A total number of 107 samples from nine human high-grade stenotic iliac arteries were tested; associated anamnesis of donors reported. Magnetic resonance imaging was employed to test the usability of the harvested arteries. Histological analyses has served to characterize the different tissue types. Prepared strips of 7 different tissue types underwent cyclic quasistatic uniaxial tension tests in axial and circumferential directions; ultimate tensile stresses and stretches were documented. Experimental data of individual samples indicated anisotropic and highly nonlinear tissue properties as well as considerable interspecimen differences. The calcification showed, however a linear property, with about the same stiffness as observed for the adventitia in high stress regions. The stress and stretch values at calcification fracture are smaller (179 +/- 56 kPa and 1.02 +/- 0.005) than for each of the other tissue components. Of all intimal tissues investigated, the lowest fracture stress occurred in the circumferential direction of the fibrous cap (254.8 +/- 79.8 kPa at stretch 1.182 +/- 0.1). The adventitia demonstrated the highest and the nondiseased media the lowest mechanical strength on average.

Aged↗

Analytical results on a Wilson-Cowan neuronal network modified model.

Wilson-Cowan model is employed in studies concerning neuronal networks. This model consists of two nonlinear differential equations that represent the interaction between excitatory and inhibitory populations of neurons. The mutual influence of these populations is described through a sigmoidal function, which is usually chosen as the hyperbolic tangent or the logistic curve. Both choices make difficult theoretical analyses. Here we choose another sigmoidal function and analytically obtain the set of parameter values for which an asymptotically stable limit cycle exists. This result is potentially useful to analytical and numerical works on the binding problem, which is the problem of creating a coherent representation of objects from the oscillatory activity of spatially separated cortical columns.

Humans↗

A fibril reinforced nonhomogeneous poroelastic model for articular cartilage: inhomogeneous response in unconfined compression.

The depth dependence of material properties of articular cartilage, known as the zonal differences, is incorporated into a nonlinear fibril-reinforced poroelastic model developed previously in order to explore the significance of material heterogeneity in the mechanical behavior of cartilage. The material variations proposed are based on extensive observations. The collagen fibrils are modeled as a distinct constituent which reinforces the other two constituents representing proteoglycans and water. The Young's modulus and Poisson's ratio of the drained nonfibrillar matrix are so determined that the aggregate compressive modulus for confined geometry fits the experimental data. Three nonlinear factors are considered, i.e. the effect of finite deformation, the dependence of permeability on dilatation and the fibril stiffening with its tensile strain. Solutions are extracted using a finite element procedure to simulate unconfined compression tests. The features of the model are then demonstrated with an emphasis on the results obtainable only with a nonhomogeneous model, showing reasonable agreement with experiments. The model suggests mechanical behaviors significantly different from those revealed by homogeneous models: not only the depth variations of the strains which are expected by qualitative analyses, but also, for instance, the relaxation-time dependence of the axial strain which is normally not expected in a relaxation test. Therefore, such a nonhomogeneous model is necessary for better understanding of the mechanical behavior of cartilage.

Biomechanical Phenomena↗

Cantonese consonantal development: towards a nonlinear account.

Descriptions of the development of prosodic and segmental tiers of children's phonological systems have been derived from investigations of the development of English. This paper provides a preliminary description of phonological tier development in Cantonese-speaking children. Eight children, (two each at 1;7, 2;6, 3;5, and 4;2 years) named 95 pictures. The data were analysed for word, syllable, onset-rime, skeletal, and segmental tiers. The results suggested a developmental order in the acquisition of hierarchical features. Decreasing order of accuracy of the tiers was word = syllable > onset-rime = skeletal > segmental. A model of feature geometry was adopted to describe the acquisition of features. An interesting finding is the way the laryngeal feature (aspiration) was combined with place contrasts one at a time rather than all at once.

Child, Preschool↗

The nonlinear dynamical hypothesis in science education problem solving: a catastrophe theory approach.

The current study tests the nonlinear dynamical hypothesis in science education problem solving by applying catastrophe theory. Within the neo-Piagetian framework a cusp catastrophe model is proposed, which accounts for discontinuities in students' performance as a function of two controls: the functional M-capacity as asymmetry and the degree of field dependence/independence as bifurcation. The two controls have functional relation with two opponent processes, the processing of relevant information and the inhibitory process of dis-embedding irrelevant information respectively. Data from achievement scores of freshmen at a technological college were measured at two points in time, and were analyzed using dynamic difference equations and statistical regression techniques. The cusp catastrophe model proved superior (R(2)=0.77) comparing to the pre-post linear counterpart (R(2)=0.46). Besides the empirical evidence, theoretical analyses are provided, which attempt to build bridges between NDS-theory concepts and science education problem solving and to neo-Piagetian theories as well. This study sets a framework for the application of catastrophe theory in education.

Humans↗

Investigation of vibration characteristics of the ligamentous lumbar spine using the finite element approach.

A nonlinear, three-dimensional finite element model of the ligamentous L4-S1 segment was developed to analyze the dynamic response of the spine in the absence of damping. The effects of the upper body mass were simulated by including a mass of 40 kg on the L4 vertebral body. The modal analyses of the model indicated a resonant frequency of 17.5 Hz in axial mode and 3.8 Hz in flexion-extension mode. Accordingly, the predicted responses for the cyclic load of -400 +/- 40 N applied at four different frequencies (5, 11, 16.5, and 25 Hz) were compared with the corresponding results for axial compressive static loads (-360, and -440 N). As compared to the static load cases, the predicted responses were higher for the cyclic loading. For example, the effect of cyclic load at 11 Hz was to produce significant changes (9.7-19.0 percent) in stresses, loads transmitted through the facets, intradiscal pressure (IDP), disk bulge, as compared to the static load predictions. The responses were found to be frequency dependent as well; supporting the in vivo observations of other investigators that the human spine has a resonant frequency. For example, the 11 Hz model (DYN11) compared to the DYN5 model showed an increase in majority of the predicted parameters. The parameters showed an increase with frequency until 17.5 Hz (resonant frequency of the model); thereafter a decrease at 25 Hz.(ABSTRACT TRUNCATED AT 250 WORDS)

Biomechanical Phenomena↗

Performance of a computer system for recording and analysing eye gaze position using an infrared light device.

Our aim is to develop a computer system in order to study the visual scanning and eye fixation during exploration of image. The system uses an infrared device to detect the horizontal and vertical eye movements. In this paper, our interest is concentrated mainly on the calibration procedure. More precisely, on the correction of the nonlinearity in the oculomotor for individual subject's eyes. An adaptive calibration algorithm is developed. The algorithm uses a polynomial model and the optimal correction is obtained by using a mean square error criterion. The paper presents also a method to correct head movements. Experiments show that the proposed approach is fast and accurate for the study of visual perception and recognition processes.

Algorithms↗

A new statistical method for identifying interconnections between neuronal network elements.

A new method is proposed to analyse dependencies in point processes, which takes into account specific character of neuronal activity. Simulation modelling of neuronal network revealed that the estimated weight of connection depends monotonically on the value of the model synaptic strength. In contrast to the crosscorrelation, the method allows for nonlinear interconnections and does not require point processes to be stationary and samples to be large. Examples are presented of the method's application to neurophysiological data analysis.

Animals↗

A Green's function method for analysis of oxygen delivery to tissue by microvascular networks.

A theoretical model is formulated for analyzing oxygen delivery from an arbitrary network configuration of cylindrical microvessels to a finite region of tissue. In contrast to models based on the classical Krogh cylinder approach, this model requires no a priori assumptions concerning the extent of the tissue region supplied with oxygen by each vessel segment. Steady-state conditions are assumed, and oxygen consumption in the tissue is assumed to be uniform. The nonlinear dissociation characteristics of oxyhemoglobin are taken into account. A computationally efficient Green's function approach is used, in which the tissue oxygen field is expressed in terms of the distribution of source strengths along each segment. The utility of the model is illustrated by analyses of oxygen delivery to a cuboidal tissue region by a single segment and by a six-segment network. It is found that the fractional contribution of the proximal segments to total oxygen delivery increases with decreasing flow rate and metabolic rate.

Animals↗

The revised velocity-strain relationship: phase-plane analysis of left ventricular function and dysfunction.

Cyclical cardiac mechanical performance has been described by plotting mid-wall left ventricular circumferential velocity or strain rate (V) as a function of instantaneous mid-wall strain (epsilon). This results in individual velocity-strain (V-epsilon) parameters. For any given individual, a standard velocity-strain plot is represented by a sinusoidally varying strain and strain rate. Three standard velocity-strain variables are then defined. The peak velocity, or peak strain rate (VM), the cycle strain at VM (epsilon M), and the system time constant (tau M). The individual velocity-strain parameters are then divided by these standard V-epsilon parameters to result in normalized V-epsilon parameters for both cardiac systole and cardiac diastole. Thirty-six patients were evaluated, consisting of four groups: Normals (N = 15 patients), Compensated Volume Overload (CVO = 6 patients), Decompensated Volume Overload (DVO = 9 patients) and Congestive Cardiomyopathy (CCM = 6 patients). Five individual velocity-strain parameters significantly differentiate the CCM group from the N group. However, they do not differentiate CVO group and DVO group from the N group. Two standard-epsilon parameters and one normalized V-epsilon parameter significantly differentiated the CVO group and the DVO group from the N group. Two standard V-epsilon parameters and one normalized V-epsilon parameter significantly differentiated the CCM group from the N group. It is recommended that future phase-plane analyses of non-linear cardiac phenomena include both standardization and normalization techniques.

Adult↗

Socioeconomic status modifies heritability of IQ in young children.

Scores on the Wechsler Intelligence Scale for Children were analyzed in a sample of 7-year-old twins from the National Collaborative Perinatal Project. A substantial proportion of the twins were raised in families living near or below the poverty level. Biometric analyses were conducted using models allowing for components attributable to the additive effects of genotype, shared environment, and nonshared environment to interact with socioeconomic status (SES) measured as a continuous variable. Results demonstrate that the proportions of IQ variance attributable to genes and environment vary nonlinearly with SES. The models suggest that in impoverished families, 60% of the variance in IQ is accounted for by the shared environment, and the contribution of genes is close to zero; in affluent families, the result is almost exactly the reverse.

Biometry↗

Relationship of body composition measures and menstrual cycle length.

Menstrual cycle disruption has been observed in women with low body weight due to anorexia nervosa, or to athletics. However, the association of the full range of body composition measures with cyclicity has not been determined. Therefore, the purpose of this study was to determine the strength and direction of association between body composition measures (Quetelet Index, body fat mass, and body lean mass) and menstrual cycle length. Menstrual cycle diaries were distributed to women aged 24-45 in the Michigan Bone Health Study beginning in 1992. A total of 4392 menstrual cycles from 436 women were analysed from the first year of this ongoing study. Body composition measures (Quetelet Index or body mass index (kg/m2), body fat mass and body lean mass (kg) were obtained at annual clinic visits by means of dual-energy X-ray absorptiometry (DEXA). Mixed-model analyses were used to determine the degree of association between menstrual cycle length and body composition measures, controlling for age. There was a significant positive association with cycle length for each body composition measure. The relationship between each body composition measure and cycle length was nonlinear with the longest mean cycle lengths occurring with greater BMI, body fat mass or body lean mass. Longer cycle length was also noted at the lowest levels of BMI and body fat mass. These results may account for the purported later age at menopause for obese women.

Adult↗

Alterations in mechanical behaviour of articular cartilage due to changes in depth varying material properties--a nonhomogeneous poroelastic model study.

The depth dependence of the material properties is present in normal adult cartilage and is believed to have significant implications in its normal mechanical function. Cartilage pathology may alter the depth dependence, e.g. a reduced depth dependence of the fibril stiffness has been observed in osteoarthritic cartilage. The objective of the present study is to investigate the alterations in the mechanical response of articular cartilage when the depth dependence of the material properties is varied to simulate healthy and pathological situations. This study is made possible by a recently developed nonhomogeneous poroelastic model. Depth variations of the strains and stresses for individual material phases (collagen, proteoglycan and fluid) are obtained for cartilage disks in unconfined compression using the finite element method. The mean nominal axial strain considered is up to 15%, while the axial strain at the articular surface can reach 33%. This paper demonstrates how the mechanical behaviours of cartilage are affected by individual depth dependent cartilage properties, while such observations are not fully available in experimental investigations. This study suggests the possibility of diagnosing cartilage health by analysing its mechanical behaviours.

Animals↗

Exploring function estimators as an alternative to regression in psychology.

Most forms of regression analysis make assumptions about the relationships between the variables being modeled. As a consequence, it can be difficult to know which form of analysis is most appropriate for a given data set. In this article, we explore the idea that function estimators might provide a better alternative in many situations. Function estimators discover the best function to link dependent and independent variables, no matter what form this takes. Four studies demonstrate that one type of function estimator (a neural network) not only performs the same tasks as linear regression and nonlinear regression, but often performs these tasks better and with more flexibility. Moreover, neural networks allow a useful secondary analysis in which useful groups of people can be identified. We recommend that function estimators be used in preference to regression-based techniques for many analyses. The Matlab script used to write this article may be downloaded from www.psychonomic.org/archive/.

Adolescent↗