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PubMed1980

Embryonic carcinosarcoma (mixed tumour) of the pineal gland.

The present paper reports on a pineal gland tumour in an 8-year-old male child. Microscopic examination revealed a carcinomatous and a sarcomatous component. The aspect was characteristic of mixed embryonic carcino-sarcoma described in germ cell layer tumours of the gonads and kidney (Wilms' tumour). Ultrastructurally, the mixed character of the tumour was confirmed and also more differentiated elements were found differing from the appearances described in germ cell layer tumours. On the basis of the morphological examination it is concluded that at least in a proportion of the malignant mixed tumours of the pineal gland, their origin is to be found in the local neural elements and not the extraneural ones.

Brain Neoplasms↗
PubMed1994

Pilomatrical carcinosarcoma of the cheek with subsequent pulmonary metastases. A case report.

We report a case of malignant pilomatrixoma with a pronounced biphenotypic morphology. The lesion, which was excised from the cheek of a 36-year-old man, was composed of a large pilomatrixoma lying within a spindled, sarcomatoid stroma. Fourteen months later, the tumor metastasized to the right upper lobe of the lung. We describe the tumor's pathology, histology, and immunochemistry and discuss the differential diagnosis. We also speculate on its histogenesis.

Adult↗