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[The use of domestic silicone oil in the treatment of complicated retinal detachment].

Vitrectomy and domestic silicone oil were used in the treatment of 42 eyes with complicated retinal detachment, and the retina was reattached in 34 cases or a rate of 80%, which dropped to 54% in 4-24 months postoperative. Among 7 eyes with successful retinal attachment and silicone oil removal, 1 eye developed recurrent retinal detachment. The therapeutic effect of silicone oil and operative complications were discussed. Removal of intravitreal silicone oil 3-6 months after injection was necessary to avoid adverse consequences. The study indicated that pars plana vitrectomy with silicone oil injection was an effective procedure in the management of complicated retinal detachment.

Eye Diseases↗

Comparison of lesions predisposing to rhegmatogenous retinal detachment by race of subjects.

Because rhegmatogenous retinal detachments are thought to be much less common in blacks than in whites, we compared the incidence of various lesions known to cause or predispose to this condition (synchysis senilis, posterior vitreous detachment, breaks, tears, and holes of the peripheral fundus, and lattice degeneration of the retina) in a series of postmortem eyes on the basis of race. Our statistical analysis also included trauma, myopia, and chorioretinitis. The series included 322 black subjects and 2,012 white subjects. The subjects ranged in age from 20 to 93 years at the time of death. Although the initial data showed a racial difference in the incidence of synchysis senilis of grade 3 (50% destruction) or higher and posterior vitreous detachment (P = .033 and P = .021, respectively), we found no difference when the data were age-corrected.

Adult↗

Outcomes of vitrectomy with inferior retinectomy in patients with recurrent rhegmatogenous retinal detachments and proliferative vitreoretinopathy.

PURPOSE: To report the anatomic and functional outcomes of patients treated with vitrectomy and inferior retinectomy for recurrent, rhegmatogenous retinal detachment complicated by proliferative vitreoretinopathy (PVR). DESIGN: Retrospective, noncomparative, interventional case series. PARTICIPANTS: Fifty-six patients with recurrent, rhegmatogenous retinal detachments complicated by PVR who underwent an inferior retinectomy for repair. METHODS: Retrospective review over a 6-year period of patients treated with vitrectomy and inferior retinectomy. MAIN OUTCOME MEASURES: The primary outcome was anatomic success, defined as complete retinal reattachment. Secondary outcomes included change in visual acuity, the mean number of operations required for complete retinal reattachment, number of operations before retinectomy, use of silicone oil tamponade, location and extent of retinectomy, whether lensectomy was undertaken, and incidence of postoperative complications. RESULTS: Complete retinal reattachment was achieved in 52 of 56 patients (93%), with a mean follow-up of 25 months (range, 6-70 months). After retinal reattachment, visual acuity was improved or stabilized in 39 of 56 patients (70%). The mean number of operations for retinal detachment before diagnosis of PVR requiring retinectomy was 1.8 (range, 1-5). Patients undergoing radical anterior vitreous base dissection and lensectomy at the time of first retinectomy had a higher success rate than those who did not: 74% versus 38%, respectively (P = 0.011). Furthermore, tamponade with silicone oil had a higher success rate than tamponade with gas: 71% versus 18%, respectively (P = 0.002). Of the 56 patients, 9 (16%) had 1 or more of the following complications: keratopathy requiring penetrating keratoplasty (n = 4), glaucoma requiring aqueous shunt device (n = 3), and hypotony (n = 3). Silicone oil removal was performed in 26 of 45 patients (58%) before the last follow-up visit, with a 1 in 26 (4%) redetachment rate. CONCLUSIONS: When combined with anterior base dissection, inferior retinectomy may be useful in the surgical treatment of complex PVR-related retinal detachment. The authors show that with lensectomy, radical anterior base dissection, and inferior retinectomy, anatomic success rates are improved and visual function can be maintained. In addition, silicone oil offers an advantage over gas tamponade in these cases.

Aged↗

[The clinical application of perfluorotributylamine liquid in the complicated retinal detachment].

OBJECTIVE: To evaluate the clinical application value of perfluorotributylamine liquid (PFTL) made in China in the complicated retinal detachment. METHODS: PFTL was injected into eyeball after vitreoretinal surgery, it could open funnel of retinal detachment, push subretinal fluid out from peripheral hole and flat and immobilize the posterior retinal during vitreoretinal surgery. In eyes with giant tears, PFTL could unfold and fix retinal flap. RESULTS: The retinas in all cases with giant tears were reattached, and sixty per cent in the eyes with PVR-D2-D3 reattached. In 8 eyes the visual acuity was improved. CONCLUSION: PFTL is valuable in treatment of complicated retinal detachment. It facilitates vitreoretinal surgery, obviates the potential complications.

Adolescent↗

Outcomes of vitreoretinal surgery for retinal detachment after LASIK for myopia.

PURPOSE: To report and compare outcomes of vitreoretinal surgery for repair of retinal detachment in myopic patients with and without previous laser-assisted in situ keratomileusis (LASIK). METHODS: This is a descriptive retrospective observational study with a control group for comparison that consisted of the analysis of clinical and surgical charts of patients who underwent vitreoretinal procedures for retinal detachment at the Fundación Oftalmologica Nacional between January 1995 and December 2002. The authors identified those myopic patients who had previous history of LASIK and an age- and myopia-matched control group without refractive surgery. RESULTS: The sample contains 24 myopic eyes of 22 patients with previous LASIK and 23 myopic eyes without previous LASIK in the control group, matched by age and myopia. Mean refractive error was -9.4 D before LASIK for the cases group and -11.2 for the control group. Poor preoperative best-corrected visual acuity was present in 71% of cases and 61% of controls (p=0.489). Macula off retinal detachment was found in 17 eyes in both groups. Five eyes required at least two procedures, achieving 91% (20 eyes) reattachments at the end of follow-up in each group. Final best-corrected visual acuity was better than 20/100 in 15 eyes (62.5%) in the LASIK group and 17 eyes (74 %) in the control group (p=0.659). CONCLUSIONS: Retinal detachment in patients with previous myopic LASIK has similar characteristics as in myopic patients without refractive surgery. Current vitreoretinal surgery is of good prognosis as the retina was successfully reattached in most cases in both groups.

Adolescent↗

[Forty years' contemporary retinal detachment surgery (author's transl)].

A survey is given on the evolution of retinal detachment surgery during the past four decades. Contributions of the ophthalmological school of Vienna are particularly considered. The review includes simple diathermy-coagulation with subretinal drainage, the undermining operation of Lindner and his eye ball shortening procedure, the combined operation (sealing of retinal breaks by diathermy plus scleral resection), and vitreous tamponade using sodium hyaluronate. All these methodes have been widely replaced during the past years by cryopexy with plombage, and by encircling procedures. Though the rate of success could not be definitely increased, the introduction of the modern methods implies technical facilities for the eye surgeon, and advances for the treated patients. The evolution of retinal detachment surgery is not yet terminated, and further progress can be taken as granted. Retinal detachment surgery with very short hospitalization may become practicable in near future.

Austria↗

The efficacy of silicone oil for complicated retinal detachments in the pediatric population.

OBJECTIVE: To evaluate the efficacy of silicone oil as an intraocular tamponade for complicated retinal detachments in the pediatric population. DESIGN: Case series. SETTING: Referral practice at a major university hospital eye center. PATIENTS: Consecutive referred sample of 48 cases of complicated retinal detachments in children 16 years old or younger. Forty-two percent of the patients had traumatic injuries, and 35 of the eyes had undergone at least one previous retinal surgery. The minimum follow-up was 6 months, with an average follow-up of 23 months. INTERVENTIONS: Pars plana vitrectomy, silicone oil injection, and advanced vitreoretinal surgical techniques. MAIN OUTCOME MEASURES: Successful repair of complicated retinal detachment, improved visual acuity post-operatively, and frequency of complications. RESULTS: The postoperative visual acuity at the last follow-up examination was counting fingers or better in eight (17%) of the 48 cases, and only two eyes saw 20/200 or better. In the 46 eyes in which the retinal status could be determined, 16 retinas (35%) were successfully reattached at last follow-up. Significant complications included corneal opacification (62%) and hypotony (58%). Postoperative glaucoma was not a problem. CONCLUSIONS: In the pediatric population with complicated retinal detachments, silicone oil used for intraocular tamponade has disappointing results due to a low rate of sustained retinal reattachment, poor visual rehabilitation, and a high complication rate.

Adolescent↗

Dermal ridge configurations in retinal detachment.

An analysis of dermal ridge configuration in 95 retinal detachment patients showed characteristic association with different aetiological bases of the condition like myopia, aphakia, vitreous degeneration and idiopathic factors. The study revealed a significantly high frequency of whorls on fingers and low mean interdigital ridge counts in the patients as compared to controls. Aphakic detachments showed maximum and vitreous degeneration detachments minimum variation from controls for all characters except the main line terminations. Of all the parameters studied, main line terminations contributed maximum for the variation between the detachment types. The results are discussed in light of the contribution of dermatoglyphic characters to the aetiology of retinal detachment.

Adult↗

[Triamcinolone-assisted vitrectomy in the treatment of recurrent retinal detachment due to myopic macular hole].

PURPOSE: To report the use of triamcinolone-assisted vitrectomy to assess the cause of vitrectomy failure in the treatment of retinal detachment due to myopic macular hole. OBSERVATIONS: We report the cases of three myopic patients presenting with recurrent retinal detachment due to macular hole after initial vitrectomy treatment with posterior vitreous detachment, a systematic attempt at membrane peeling, and gas injection (SF6). No retinal traction or tear other than the macular hole was observed. The recurrence of retinal detachment was treated with vitrectomy and intraoperative use of triamcinolone, which demonstrated persistent posterior hyaloid and thin and strongly adherent membrane remnants in each case. Anatomic success was obtained after peeling these structures. CONCLUSION: Intraoperative use of triamcinolone reduces the risk of overlooking hyaloid or membrane remnants during vitrectomy for the treatment of myopic retinal detachment. Transparent remnants of posterior hyaloid and membranes were visualized by triamcinolone-assisted vitrectomy. They could lead to traction on the retina and explain the failure of the initial vitrectomy. Anatomic success was obtained after peeling these structures.

Aged↗

Optical coherence tomography findings in the macula after treatment of rhegmatogenous retinal detachments with spared macula preoperatively.

PURPOSE: To present the postoperative optical coherence tomography (OCT) findings of the macula in rhegmatogenous retinal detachment with spared macula preoperatively. METHODS: Eleven of 46 patients who underwent surgery for rhegmatogenous retinal detachment had an uninvolved macula preoperatively. Scleral buckling without intravitreous gas injection was the operation used in all eyes. All 11 patients were examined before and after treatment with slit-lamp biomicroscopy, indirect ophthalmoscopy, fundus photography, fluorescein angiography, and OCT. RESULTS: In 3 of the 11 patients with rhegmatogenous retinal detachment and uninvolved macula preoperatively, fluid was identified with OCT in the macula after successful treatment. OCT showed that the fluid gradually diminished and finally disappeared 5 to 7 months after the scleral buckling procedure. The fluid in the macula became visible with slit-lamp biomicroscopy in only one of the three patients. CONCLUSION: Subretinal fluid in a preoperatively uninvolved macula can be found after successful treatment of rhegmatogenous retinal detachment. If the fluid is located in the fovea, the visual acuity decreases and does not reach the preoperative levels. OCT identifies the presence of fluid and contributes to the study of the fluid's evolution.

Adult↗

[On the prophylactic treatment in retinal detachment (author's transl)].

Within a period of three years, 152 eyes in 149 patients underwent prophylactic treatment for retinal lesions. The elements are considered that would move the surgeon to propose to the patient a prophylactic treatment. No complications were found in any of the eyes that were treated, however a retinal detachment occurred in two eyes, 6 to 8 months after treatment. Retinal lesions treated by prophylactic means are compared with those found in 500 eyes operated for retinal detachment during the same period. The results of this study leads to the conclusion that a real risk of retinal detachment is more dangerous than the possible consequences of prophylactic treatment.

Adolescent↗

Outcomes of primary rhegmatogenous retinal detachment in myopes of five or more diopters.

OBJECTIVE: To analyze surgical outcomes of primary rhegmatogenous retinal detachment in high myopes. MATERIALS AND METHODS: Medical records of 201 patients who underwent vitreoretinal surgeries for primary retinal detachments were reviewed. Fifty-two eyes of 51 patients with at least 5.00 diopters (D) of myopia were included. RESULTS: The mean refractive error was -9.8+/-5.4 D (mean +/- SD). Macula was off in 29 (55.8%) eyes. Thirty-six (69.2%) and 16 (30.8%) eyes received scleral buckling (SB) and pars plana vitrectomy (PPV), respectively. Primary anatomical success rate was 86.1% and 75.0% in the SB and PPV group, respectively. The anatomical success rate after 2 operations was 94.4% and 100% in the SB and PPV group, respectively. Twenty-three (63.1%) patients from SB group and 10 (62.5%) patients from PPV group attained postoperative best-corrected visual acuity of 20/60 or better. CONCLUSION: The anatomical and visual outcomes of primary rhegmatogenous retinal detachment in myopes of five or more diopters seem favorable after surgery.

Adult↗

Retinal detachment following surgery for congenital cataract: presentation and outcomes.

AIMS: To review the current management and outcomes of retinal detachment following cataract surgery in childhood. METHODS: A retrospective review of 59 eyes of 52 patients. RESULTS: In 37% of patients, the fellow eye was blind (<3/60). The macula was detached at presentation in 81% of eyes. The detachment was obscured by residual lens matter, or a miotic pupil in 67% of eyes that had cataract surgery before 1970, but in only 30% of eyes operated after 1970. The retina was reattached with one operation in 59% of eyes, and final reattachment was achieved in 81%. No retina was reattached by scleral buckling alone. Visual outcomes were slightly better in eyes that had retinal detachment repair after 1 January 1998. Nine patients were blind in both eyes at the latest follow-up. CONCLUSIONS: Retinal detachment following childhood cataract surgery remains a serious condition. There has been some improvement in the prognosis due to a combination of advances in childhood cataract surgery as well as to improvements in the management of retinal detachment. Early recognition and prompt surgery, using an internal approach, may prevent blindness in most cases.

Adult↗

[Age of onset of rhegmatogenous retinal detachment analyzed by Weibull distribution function].

We reviewed a series of 426 case or rhegmatogenous retinal detachment due to idiopathic retinal break and characterized the age at onset using a vital statistics model, Weibull distribution. When cases were divided into groups based on the type of retinal break, the cumulative frequency of each group could be described by the model. The equatorial atrophic hole group showed a frequency distribution which starts at about 7.5 years, culminates at about 20 years and terminates at about 40 years. The tractional tear group revealed two distinct distributions depending upon refractive errors; the non-high myopic subgroup showed a distribution which starts at 30 years and peaks at 60 years, and the high myopic subgroup had a distribution which starts at about 15 years and peaks at about 40 years. The macular hole group showed a distribution which starts in the second half of the third decade and peaks at about 60 years. The findings are consistent with the view that pathomechanisms having differing time courses are responsible for the age distribution at onset of rhegmatogenous retinal detachment caused by various types of retinal break.

Adolescent↗

[Clinical and experimental results in the treatment of massive periretinal proliferation (MPP), a retinal detachment with a most unfavorable prognosis].

Today eyes with massive periretinal proliferation which are often seen after uncured retinal detachments or after perforating injuries can be cured at least in 25 to 35% of the cases, even with modern surgical techniques. This is due to proliferation of cells, which enter through different pathways--retinal tears, perforating wounds of sclera and chorioidea, damaged retina or retinal vessels--into the vitreous and form membranes, which prevent the retina to attach. In the vitreous gel these cells of different origin can transform into fibroblast-like or myofibroblast-like cells. They also behave in the same way like fibroblasts or myofibroblasts and cause a kind of excessive wound healing and scar formation in the vitreous cavity. With the use of modern vitreous techniques we could cure nearly 43% of 14 patients with MPP after uncured retinal detachments or after perforating injuries. Because mechanical removal of intravitreal and periretinal membranes alone turned out to be unsuccessful in nearly 60%, methods of medical therapy to suppress this cell-activity seemed to be rather needed. By animal experiment we tried to produce retinal detachments by transplantation of homologue fibroblasts into the vitreous cavity of rabbit eyes, and observed traction detachments in 55% of the eyes. Histologic examination showed a rapid change of loose, round fibroblasts into elongated cells with long nuclei, which formed strands and caused vasoproliferation, especially where the strand reached the rabbit retina. By means of autoradiography the peak of cell activity turned out to be in the 3rd week after cell-transplantation and further examinations of the optic disc showed, that the vascular endothelium cell might be one source of the proliferation. There was no difference between the number of eyes which developed retinal detachment in the aphakic eyes and in the lentectomized and vitrectomized eyes, but we observed the clinical appearance of MPP earlier and more pronounced in the lentectomized and vitrectomized eyes. In the last experiment we tried to inhibit intraocular proliferation with intravitreal dexamethasone alcohol. This leaded to a significant reduce of the number of experimental detachments and vasoproliferations.

Adolescent↗

Retinal detachments and intraocular lenses.

1. Increasingly more patients with PPRD are seen. A retinal detachment can occur after any type of implant or cataract extraction. 2. The pseudophakic patient is better equipped than the aphakic patient to recognize symptoms of a retinal detachment, and most PPRDs are seen soon after they occur. 3. Visual access to the retina is sometimes decreased. The IOL requires more precautions. Hazy media and lens remnants are a major handicap, and the examination is more difficult and time-consuming. 4. Characteristic pseudophakogenic retinal changes or breaks are not obvious. Retinal tears are small and located near the ora serrata retinae. 5. When the breaks are found, the lengthy examination can be followed by a simple scleral buckle with minimal insult to the eye. When the breaks are not found, the treatment is extensive. 6. The anatomical and visual results are comparable to results of other rhegmatogeneous retinal detachments.

Europe↗

Acute onset of central retinal vein occlusion and retinal detachment.

The simultaneous occurrence of a central retinal vein occlusion and retinal detachment has not been previously reported. Although both are well recognized entities with characteristic appearances, their simultaneous acute onset led to a misdiagnosis in our case report. The need for a complete eye examination in the face of obvious pathology is stressed.

Humans↗