PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Aerococcus”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 91 records · Page 5Linked to original sources
PubMedDate not supplied

[The effect of Aerococcus viridans on the properties of salmonellae and staphylococci in vitro].

According to electron microscopy the repeated contacts of Aerococcus viridans 167 (industrial strain for the probiotic Aerobact production) with Salmonella typhimurium and Staphylococcus aureus caused the deep changes of cellular structure, down to bacteriolysis. Remaining viable pathogenic cells gave posterity with changed biochemical properties and virulence. S. typhimurium completely lost typical biochemical properties, its mobility and ability to be agglutinated by O-specific Salmonella serum reduced after the fifth joint passage. Sharp decrease of the leucotoxic and loss of the lethal and necrotic activity of the S. aureus toxin were observed. The latter was characterized by the smaller number of protein fractions in comparison with control series on electrophoregrams and densitograms. Pathogenic bacteria, playing a role in formation of the pathological intestinal microbiocenosis (S. typhimurium) and being hospital infections (S. aureus) acquired increased sensitivity to antibiotics. The carried out researches open some mechanisms of bactericidal and bacteriostatic action of A. viridans (group 12, Bergey, 1994) and their metabolic products, causing antagonistic effect during direct action on infectious microorganisms.

Animals↗
PubMed2002

[Aerococcus urinae and urinary tract infection].

BACKGROUND: Bacteriological investigation of urine often shows the presence of alpha-haemolytic streptococci, but the clinical significance of this finding may be unclear. Among the alpha-haemolytic streptococci found in urine is Aerococcus urinae, which is pathogenic. MATERIAL AND METHODS: We present a prospective study of the prevalence and antibiotic susceptibility of A urinae in urine samples sent to a microbiology laboratory in Norway. RESULTS: Seven out of 27 alpha-haemolytic streptococcal isolates were A urinae. This represents 0.3% of all urine isolates from our laboratory. Appropriate methods for identification and resistance determination are described. INTERPRETATION: Microbiological laboratories should include identification of A urinae in their diagnostic repertoire. Recommended treatment against A urinae is ampicillin or nitrofurantoin.

Drug Resistance, Bacterial↗
PubMed2001

Non-linear slow-binding inhibition of Aerococcus viridans lactate oxidase by Cibacron Blue 3GA.

Lactate oxidase (LOD) was purified from cells of Aerococcus viridans by phase partitioning in Triton X-114 (TX-114), ammonium sulphate fractionation and FPLC ion exchange chromatography. The purification achieved from a crude extract of A. viridans was 32-fold with a 60% recovery of activity. The isolated enzyme was a true FMN-containing LOD in tetrameric form with a subunit molecular weight of 48,000. The KM for L-lactate was 175 microM, a 6-fold less value than described in the literature. Among the inhibitors tested, Cibacron Blue 3GA showed the lowest Ki. At low concentrations, Cibacron Blue 3GA behaved as a dye-, pH- and time-dependent inhibitor. A Dixon plot of the steady-state rate showed the time-dependent inhibition to be non-linear, contrary to that described for other slow-binding inhibitors. A model to explain this phenomenon was proposed. The model implies the binding of Cibacron Blue 3GA to the isomerised form of the initial enzyme-inhibition complex (E'I).

Apoenzymes↗
PubMed2004

Urinary tract infection caused by Aerococcus viridans, a case report.

BACKGROUND: Aerococcus viridans organisms are gram-positive, usually airborne cocci that are widely distributed in hospital environments. These bacteria have infrequently been encountered as a human pathogen causing bacteremia, endocarditis and urinary tract infections. The clinical significance of these bacteria may be overlooked due to their fastidious growth and often confused with other strains of streptococci. CASE REPORT: We report a case of urinary tract infection with bacteremia caused by A. viridans in an 87 year-old male nursing home resident. The patient presented with a fever of 103 degrees F, dysuria, hematuria and weakness for three days. Urinalysis showed large amount of blood, more than one hundred white cells/HPF and 4+ bacteria. Laboratory tests revealed, white blood cell count of 2300/cu mm (neutrophils 80%, bands 7%, lymphocytes 11% and monocytes 2%), hemoglobin 15.4 gm/dL, blood urea nitrogen 23 mg/dL and creatinine 1.2 mg/dL. Urine culture yielded growth of 10(5) CFU of A. viridans. The patient was treated for ten days with levofloxacin (both IV + PO). CONCLUSIONS: To date, no clinical case report of this nature has been described implicating A. viridans in urinary tract infections. Increased awareness and more studies of this genus should lead to the identification of their potential role in human infections.

Aged↗
PubMedDate not supplied

[The lactate oxidase activity of Aerococcus viridans cultures].

The oxidase activity of Aerococcus viridans is a result of the functioning of aerobic NAD-independent lactate dehydrogenase. Two fractions of flavin-containing protein which oxidize D- and L-isomers of lactic acid are revealed during the enzymic complex electrophoresis in PAAG. The enzymic complex and eluates of both fractions possess the antagonistic activity relative to 27 test-cultures of bacteria.

Antibiosis↗
PubMed1985

Solid-state 13C and 15N nuclear magnetic resonance studies of alanine metabolism in Aerococcus viridans (Gaffkya homari).

Transport and metabolism of D- and L-alanine by Aerococcus viridans (Gaffkya homari) have been studied using cross-polarization magic-angle spinning 13C and 15N NMR spectroscopy of lyophilized whole cells, isolated cell walls, and crude extracts. For equimolar concentrations in the growth medium, about 10 times more D-alanine than L-alanine is transported into the cells. Examination of cells labeled with D-[13C]alanine and L-[epsilon-15N]lysine by double cross-polarization magic-angle spinning 15N NMR indicates that only about 20% of the D-alanine present in cell-wall peptidoglycan comes directly from the growth medium. The rest is produced by de novo synthesis. Most of the labeled D-alanine is found within peptidoglycan precursors or inverted to L-alanyl residues of soluble proteins.

Alanine↗
PubMed1980

Aerococcus viridans as a causative agent of infectious endocarditis.

Identification and properties of Aerococcus viridans isolated from the blood of a patient with infectious endocarditis are described. The role of this agent in the pathogenesis of this disease was demonstrated by repeated cultivations as well as by high titres of specific antibodies in the patient's serum. Pathogenicity of this strain for experimental animals was not demonstrated.

Animals↗
PubMed1995

Effect of cultivation conditions on glycerophosphate oxidase production by a mutant strain of Aerococcus viridans.

The effect of different concentrations of carbon source (lactose) and inducer (glycerol) on biomass and glycerophosphate oxidase (GPO) production by mutant strain of Aerococcus viridans 1509 was tested. The best combination of lactose and glycerol concentrations for good enzyme productivity was 0.5% lactose and 2.5% glycerol. Further improvement of GPO levels was achieved after scaling-up of the bioprocess and cultivation of the cells in a 3 liter laboratory bioreactor. Using 4.5 x 10(-5) m3 s-1 air flow rate during growth, GPO activity increased 20-times in comparison with cultivation in flasks.

Culture Media↗
PubMedDate not supplied

[Viridicine: a bacteriocine from "Aerococcus viridans" (author's transl)].

Viridicine, a new bacteriocine, was extracted from whole cells of Aerococcus viridans by repeated washings with Tris-HCl 5 X 10(-3) M pH 8,1, NaCl 1 M. A crude preparation of the macromolecule was not inactived by heating for one hour at 50 degrees C and was sensitive to the action of protease, lipase and catalase. The molecular weight was about 100,000. A large number of Gram-negative and Gram-positive bacteria were sensitive to viridicine action.

Bacteria↗
PubMedDate not supplied

[A biological model study of the effect of Aerococcus viridans on pathogenic bacteria].

Morphological researches studies showed that the treatment of infected skin wounds with Aerobact quickly eliminated inflammation, promoted regeneration of damaged tissues, that actively stimulated formation of granulations. A decrease of S. aureus virulence which completely or partially loose lethal and necrotic activity is one of the reasons of the observed phenomenon. On the model of S. typhimurium infection the expressed protective action of bacteria of Aerococcus genus was shown; this gives us a good prospect in the expansion of the indications for application of probiotic Aerobact.

Animals↗
PubMed1987

Aerococcus bacteremia associated with granulocytopenia.

Two cases of bacteremic infection due to aerococci in granulocytopenic patients with acute leukemia and oral mucositis are described. Strains isolated from blood cultures of both patients were resistant to the antibiotics given orally for prophylaxis. One patient died in septic shock; surveillance cultures from oral washings in the other repeatedly showed high concentrations of aerococci. Aerococci were also isolated from surveillance cultures taken from 5 of 17 other patients with acute leukemia; however, their viable counts were lower than in the surviving patient.

Adult↗