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Results of cosmic radiation dose field measurements aboard the "Salyut-6" orbital station.

During the 3rd main expedition on board the "Salyut-6" orbital station in 1979 the integral characteristics of cosmic radiation were measured in various positions inside the manned modules (experiment "Integral"). Measurements were performed with thermoluminescent dosimeters, photographic films and solid state plastic detectors supplied for the experiment by specialists of the USSR, Bulgaria, Hungary, GDR and Romania. The dose gradient inside the manned modules of the station amounted to 70% for long intervals of time. During the experimental period the dose rate inside the station was 15 to 30 mrad per day. The mean flux of particles with Z > or = 6 and LET > or = 200 keV/micrometer was found to be 0.22 cm-2 or day-1.

Cosmic Radiation↗

Anencephalus, drinking water, geomagnetism and cosmic radiation.

The mortality rates from anencephalus from 1950-1969 in Canadian cities are shown to be strongly correlated with city growth rate and with horizontal geomagnetic flux, which is directly related to the intensity of cosmic radiation. They are also shown to have some association with the magnesium content of drinking water. Prior work with these data which showed associations with magnesium in drinking water, mean income, latitude and longitude was found to be inadequate because it dismissed the observed geographic associations as having little biological meaning, and because the important variables of geomagnetism and city growth rate were overlooked.

Anencephaly↗

The biological effectiveness of HZE-particles of cosmic radiation studied in the Apollo 16 and 17 Biostack experiments.

The Biostack experiments I and II were flown on board the Apollo 16 and 17 command modules in order to obtain information on the biological damage produced by the bombardment of heavy high-energy (HZE) particles of cosmic radiation during spaceflight. Such data are required for estimating radiation hazards in manned spaceflight. Seven biological systems in resting state (Bacillus subtilis spores, Colpoda cucullus cysts, Arabidopsis thaliana seeds, and eggs of Artemia salina, Tribolium castaneum and of Carausius morosus) were accommodated in the two Biostacks. By using a special sandwich construction of visual track detectors and layers of biological objects, identification of each hit biological object was achieved and the possible biological damage correlated with the physical features of the responsible HZE-particle. In the different systems the degree of damage depended on whether the hit cell was replaceable or not. A high sensitivity to HZE-particle bombardment was observed on Artemia salina eggs; 90% of the embryos, which were induced to develop from hit eggs, died at different developmental stages. Malformations of the abdomen or the extremities of the nauplius were frequently induced. In contrast, the growth of hit Vicia faba radiculae and the germination of hit Arabidopsis thaliana seeds and hit Bacillus subtilis spores were not influenced remarkably. But there was an increase in multicaulous plants and a reduction in the outgrowth of the bacterial spores. In addition, information was obtained on the fluence of the HZE-particles, on their spectrum of charge and energy loss, and on the absorption by the Apollo spacecraft and the Biostack material itself. This will help to improve knowledge concerning radiation conditions inside of spacecrafts, necessary to secure a maximum possible protection to the astronauts.

Animals↗

Investigation of the low-energy component of primary cosmic radiation on the outside of spacecrafts.

We have developed a method to investigate the low-energy radiation environment on the outside of spacecrafts. Thereby, ultra-thin thermoluminescent (TL) detectors on the base of CaF2:Mn-PTFE are arranged in stacks and exposed to the unshielded cosmic radiation. The dose distribution within a stack is determined by successive evaluation of the thin TL sheets. The analysis of LiF thermoluminescent detector glow curves permits conclusions on the dose contribution caused by either low-energy electrons or by protons. The method was applied aboard Russian COSMOS spacecrafts as well as the MIR station. It was shown that along low-earth orbits dose rates up to 10 Gy/day within the first few mg/cm2 are typical, mainly as a result of the electron impact.

Cosmic Radiation↗

Aircrew exposure from cosmic radiation on commercial airline routes.

As a result of the recent recommendations of the ICRP 60, and in anticipation of possible regulation on occupational exposure of Canadian-based aircrew, an extensive study was carried out by the Royal Military College of Canada over a one-year period to measure the cosmic radiation at commercial jet altitudes. A tissue-equivalent proportional counter was used to measure the ambient total dose equivalent rate on 62 flight routes, resulting in over 20,000 data points at one-minute intervals at various altitudes and geomagnetic latitudes (i.e. which span the full cut-off rigidity of the Earth's magnetic field). These data were then compared to similar experimental work at the Physikalisch Technische Bundesanstalt, using a different suite of equipment, to measure separately the low and high linear energy transfer components of the mixed radiation field, and to predictions with the LUIN transport code. All experimental and theoretical results were in excellent agreement. From these data, a semiempirical model was developed to allow for the interpolation of the dose rate for any global position, altitude and date (i.e. heliocentric potential). Through integration of the dose rate function over a great circle flight path, a computer code was developed to provide an estimate of the total dose equivalent on any route worldwide at any period in the solar cycle.

Aircraft↗

Examination of evidence for a preferred axis in the cosmic radiation anisotropy.

We examine previous claims for a preferred axis at (b,l) approximately (60,-100) in the cosmic radiation anisotropy, by generalizing the concept of multipole planarity to any shape preference. Contrary to earlier claims, we find that the amount of power concentrated in planar modes for l = 2,3 is not inconsistent with isotropy and Gaussianity. The multipoles' alignment, however, is indeed anomalous, and extends up to l = 5 rejecting statistical isotropy with a probability in excess of 99.9%. There is also an uncanny correlation of azimuthal phases between l = 3 and l = 5. We are unable to blame these effects on foreground contamination or large-scale systematic errors. This reappraisal may be crucial in identifying the theoretical model behind the anomaly.

Journal Article↗

[Effect of heavy charged particles in galactic cosmic radiation on seeds].

The experiments were carried out on Lactuca sativa seeds exposed for 20, 66, 123 and 308 days in a biostack also containing physical detectors of heavy charged particles. The purpose of the experiments was to measure the yield of aberrant cells and its dependence on the exposure time and the site where particles hit the object. The cytogenetic examination demonstrated a significant difference between the seeds that were or were not hit by heavy charged particles. This is indicative of a significant contribution of galactic cosmic radiation to the radiobiological effect. The yield of aberrant cells as a function of the localization of heavy charged particles in the seed was established. The most sensitive target was the root meristem.

Chromosome Aberrations↗

[Study of the genotoxic effects of exposure to cosmic radiation in flight personnel using cytogenetic and molecular techniques].

BACKGROUND: The ever-increasing use of air travel suggests the need to study health risks in flight personnel, by means of correct exposure assessment and evaluation of genotoxic effects. OBJECTIVES: After taking into consideration occupational risk and possible confounding factors, we studied 48 pilots and flight technicians engaged on long-haul flights together with a control group of 48 ground staff, with the aim of evaluating genotoxic effects of cosmic radiation exposure. On 36/48 subjects we also evaluated the presence of DNA damage (single and double strand breaks). METHODS: Traditional cytogenetics, the micronucleus test and FISH analysis, were used to study chromosome aberrations, micronuclei and translocations. The Comet test was used to analyze direct DNA damage (single and double strand breaks). RESULTS: Our findings indicated a significant increase in gaps and breaks and a significant increase of frequency ratio for translocations in pilots compared to controls, but revealed a non-significant difference in unstable aberrations and micronuclei. The Comet test did not show any significant increase of DNA damage in flight personnel with respect to ground staff. CONCLUSIONS: The possibility of a correlation between translocations and cancer risk emphasizes the need to adopt preventive measures for air flight personnel.

Adult↗

Measurements on the shuttle of the LET spectra of galactic cosmic radiation and comparison with the radiation transport model.

A new class of tissue-equivalent proportional counters has been flown on two space shuttle flights. These detectors and their associated electronics cover a lineal energy range from 0.4 to 1250 keV/microns with a multichannel analyzer resolution of 0.1 keV/microns from 0.4 to 20 keV/microns and 5 keV/microns from 20 to 1250 keV/microns. These detectors provide the most complete dynamic range and highest resolution of any technique currently in use. On one mission, one detector was mounted in the Shuttle payload bay and another older model in the mid-deck, thus providing information on the depth dependence of the lineal energy spectrum. A detailed comparison of the observed lineal energy and calculated LET spectra for galactic cosmic radiation shows that, although the radiation transport models provide a rather accurate description of the dose (+/- 15%) and equivalent dose (+/- 15%), the calculations significantly underestimate the frequency of events below about 100 keV/microns. This difference cannot be explained by the inclusion of the contribution of splash protons. The contribution of the secondary pions, kaons and electrons produced in the Shuttle shielding, if included in the radiation transport model, may explain these differences. There are also significant differences between the model predictions and observations above 140 keV/microns, particularly for 28.5 degrees inclination orbit.

Aerospace Medicine↗