Are there socioeconomic gradients in stage and grade of breast cancer at diagnosis? Cross sectional analysis of UK cancer registry data.
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Aged↗
SEARCH · PubMed Health
Results for “Cross Sectional Analysis”
Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.
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Hypertension in dialysis patients: a cross-sectional analysis.
To clarify the current status of blood pressure control in chronic dialysis patients, we investigated a large group of patients undergoing dialysis in Okinawa, Japan. A set of cross-sectional data of 18 variables, including age, antihypertensive medication, dose of dialysis, blood chemistry findings and predialysis blood pressure, were obtained in 1,243 patients (524 females, 719 males) aged 14 to 93 years who were on hemodialysis in January 1991. Systolic and diastolic blood pressures in patients taking antihypertensive medication (160.8 +/- 0.8/84.6 +/- 0.5 mmHg, mean +/- SEM) were significantly (P < 0.0001) higher than in those were not taking antihypertensive medication (141.3 +/- 0.8/76.9 +/- 0.5). Stepwise regression and univariate analysis methods were used to determine the independent predictors of blood pressure. Antihypertensive medication was positively associated with systolic and diastolic blood pressure. However, the mortality rate of the two groups during the following four years did not differ (antihypertensive-medicated group 23.1% vs. non-medicated group 20.9%). In conclusion, hypertension does not appear to be adequately controlled in our dialysis patients, despite the widespread use of antihypertensive medications.
Adult↗
A cross-sectional analysis of factors that influence the detection of depression in older primary care patients.
OBJECTIVE: To determine the characteristics of depressed older patients whose mental health status is detected by their general practitioner (GP). METHOD: Cross-sectional analytical design of 218 patients scoring above the cut-off (> or = 16) of the Center for Epidemiological Studies-Depression Scale (CES-D), from a sample of 916 consecutive patients aged 60 years or over attending one of 54 randomly selected GPs in Western Australia. Prior to their medical consultation, patients completed a self-report questionnaire, which included questions about depressive symptomatology (CES-D). Following the consultation, general practitioners recorded the patient's presenting complaint(s), medication information, and mental health details on a patient summary sheet. RESULTS: Among these 218 patients, 39.9% (87/218) were correctly classified as depressed by their GP. Detection of depressive symptomatology was associated with patients who acknowledged taking sleeping tablets (OR = 2.6, 95% CI = 1.3-5.4), had CES-D scores indicative of major depression (> or = 22) (OR = 2.8, 95% CI = 1.4-5.6) and were thought to be at risk for suicide (OR = 35.1, 95% CI = 4.5-274.2). CONCLUSIONS: While GPs are most apt to detect depression among older patients with prominent mental health symptoms, many patients in this age group silently experience significant depressive symptomatology and miss the opportunity for effective treatment. The routine use of screening tools in primary care is recommended to enhance the detection rate of depression in older adults.
Adult↗
Cross-sectional analysis of the polysaccharide composition in cellulosic fiber materials by enzymatic peeling/high-performance capillary zone electrophoresis.
A combined enzymatic, chemical, and analytical approach was used to determine the cross-sectional carbohydrate composition in cellulosic fibers. The outer surface of cellulosic fibers was enzymatically removed layer-by-layer with precise quantitative control, and the monosaccharides in the peelings were subsequently analyzed by high-performance capillary electrophoresis (HPCE) after precolumn derivatization with a UV label. This method was applied to dissolving pulps and regenerated cellulose fibers, with special emphasis on the cross-sectional distribution of hemicelluloses. Commercially available enzyme solutions were used, resulting in a reproducible peeling. Significant differences were found in the hemicellulose distribution across the fiber of different dissolving pulps, dependent on both natural source (beech or spruce) and preparation process (acidic sulfite cook or prehydrolysis kraft cook). Among the dissolving pulps, beech prehydrolysis kraft pulp showed the highest enrichment of surface xylan. Similar, albeit smaller, differences were noticed between various regenerated fibers (viscose, viscose Modal, and Lyocell): a thin hemicellulose-rich outermost layer was found in all the regenerated fibers studied.
Biocompatible Materials↗
Physical activity, television viewing and body mass index: a cross-sectional analysis from childhood to adulthood in the 1958 British cohort.
OBJECTIVE: To investigate relationships between frequency of physical activity or television viewing and body mass index (BMI) cross-sectionally at six ages from childhood to adulthood, to better understand longitudinal relationships. To investigate how the relationships vary with age and gender and whether any relationships are due to confounding factors. METHODS: The 1958 British birth cohort includes all births (approximately 17 000) in one week in March 1958. BMI and physical activity frequency were recorded at 11, 16, 23, 33 and 42 y and television viewing frequency at 11, 16 and 23 y. A total of 11 109 subjects provided BMI and activity data at 42 y. Relationships between BMI and (in)activity were investigated using linear regression. RESULTS: At ages 11, 33 and 42 y in both sexes and at 23 y in female subjects, those who were more active had lower BMIs, and the relationships strengthened with age. At 42 y, the most active had a lower mean BMI than the least active, by 0.83 kg/m2 in men, and 1.03 kg/m2 in women. BMI and activity were unrelated at 16 y in female subjects, and 23 y in male subjects. At 16 y in males, the most active males had a mean BMI 0.25 kg/m2 higher than the least active. At 11 y in female subjects and 23 y in both sexes, those who watched television most frequently had higher BMIs. BMI and television viewing were unrelated at 11 y in males and at 16 y in both sexes. Relationships between BMI and activity or television viewing were largely unexplained by potential confounding factors. CONCLUSIONS: The relationship between BMI and physical activity changes with age. In early adolescence and in adulthood, a higher activity level, or lower frequency of television viewing was associated with a lower BMI. In later adolescence (16 y), television viewing and activity were unrelated to BMI, except for an unexpected BMI-activity relationship in males. We suspect this relationship in males is primarily due to selection effects, whereby physically bigger boys, with a larger BMI, are more likely to take part in exercise activity, and possibly also to BMI being a less accurate predictor of fatness in adolescent boys.
Activities of Daily Living↗
The transition from natural to controlled fertility in Taiwan: a cross-sectional analysis of demand and supply factors.
Three factors are usually proposed as inducing the transition from natural to regulated fertility. Fertility regulation may occur when the demand for children is reduced; when general attitudes toward fertility regulaton become positive; and, finally, when such factors as infant and child survival prospects and natural fertility conditions improve. Applying the Easterlin framework for fertility determination, this paper considers the effect of these factors in the shift from natural to regulated fertility in Taiwan in 1965. Cross-sectional data for continuously married women aged 35-44 are used. The results indicate that, at the initial stages of the fertility transition, it is primarily an increase in the potential output of surviving children and a decline in the subjective costs associated with fertility regulation, rahter than a decline in desired fertility, that distinguish the natural fertility subpopulation from the regulating subpopulation.
Adult↗
A cross-sectional analysis of glucose tolerance and cardiovascular disease in 67-year-old men.
The relationship between degree of glucose tolerance and cardiovascular disease has been studied in a cross-sectional population survey of 644 men born in 1913, randomly sampled and examined at the age of 67. The cohort was divided into different groups according to current diagnostic criteria for diabetes and impaired glucose tolerance. An almost 2-fold higher prevalence of hypertension, myocardial infarction, angina pectoris, and congestive heart failure was found in the group with impaired glucose tolerance compared to the group with a normal glucose tolerance. Fifty per cent of the men with impaired glucose tolerance were being treated with some drug for cardiovascular disease, usually diuretics for hypertension. Intermittent claudication showed a 2.5-fold higher prevalence among the diabetic patients. A computerized 12-lead exercise-ECG test, with a unique accuracy in measuring ST-segment changes, was performed in a subset of 135 men. This showed no association between ST-segment depression and different degrees of glucose tolerance, even when accounting for confounding factors such as treatment with beta-blocker agents or digoxin, pathological Q-waves, and differences in maximal heart rate.
Aged↗
Determinants of motor vehicle deaths in the United States: a cross-sectional analysis.
This paper uses 1987 state-level data and least-squares regression to estimate a model of motor vehicle deaths in the United States. The model includes several factors accounted for in previous cross-sectional studies of these fatalities. The estimates suggest that income, the ratio of urban to rural driving, expenditures on highway police and safety, motor vehicle inspection laws, and adult seat belt use laws with secondary enforcement provisions are inversely related to motor vehicle death rates. They also indicate that volume of driving, speed, speed variance, driving density, alcohol consumption, temperature, and a dummy variable for western states are directly related to the rates.
Accidents, Traffic↗
Smoking behaviour, cessation attempts and the influence of parental smoking in older adult women: a cross-sectional analysis from Italy.
OBJECTIVES: To investigate the association between parental smoking during infancy/adolescence and smoking prevalence in older adult women, and to provide a description of smoking and smoking cessation patterns in this subset of the population. STUDY DESIGN: Cross-sectional survey. METHODS: Between 1999 and 2001, trained physicians in 11 health agencies throughout the Abruzzo Region, Italy, conducted semi-structured interviews on 9708 women aged 50-70 years attending mammographic screening (overall response rate 89%). Information was collected on sociodemographic characteristics, smoking habits, parental smoking during their infancy and/or adolescence, and exposure to environmental tobacco smoke (ETS) inside or outside the family. RESULTS AND CONCLUSIONS: The overall prevalence of current smoking was 15.6% (n=1516), and that of former smoking was 13.2%. Women whose parent(s) smoked were more likely to be current smokers, especially if only the mother smoked (adjusted odds ratio 4.27; 95% confidence interval 2.24-8.12). Other factors significantly associated with current smoking in the multivariate analysis were younger age, lower body mass index, higher level of education, unmarried status, and exposure to ETS either inside or outside the family environment. Eighteen percent of all current smokers were non-inhalers, and more than 60% of ex-smokers quit smoking on their first attempt. Our findings expand the existing evidence suggesting that a strong effect of parental conduct on a daughter's smoking behaviour may persist throughout life. Although more research is needed, especially to clarify the role of genetic and environmental factors in determining the mother-child smoking association, our results suggest that intensifying smoking prevention efforts directed at women with children might considerably reduce the risk of ever smoking in future female generations.
Aged↗
Cross-sectional analysis of variables related to cigarette smoking in late adolescence.
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Adolescent↗
Associations of polycyclic organic matter in outdoor air with decreased birth weight: a pilot cross-sectional analysis.
The association between births that are small for gestational age and outdoor airborne polycyclic organic matter (POM) was examined in New Jersey, a highly urban state. This pilot study utilizes a cross-sectional investigation combining maternal and pregnancy outcome information from birth certificates with air toxics data from the U.S. Environmental Protection Agency Cumulative Exposure Project and census data at the census tract level. The exposure categories were based on tertiles of modeled average POM concentrations for each census tract in New Jersey. High POM exposure was positively associated with delivery of "small for gestational age" (SGA) births. After adjustment for potential individual-level confounding factors, the odds ratios for term, preterm, and all SGA were 1.22 (1.16-1.27), 1.26 (1.07-1.49), and 1.22 (1.17-1.27), respectively, for the highest exposure tertile in the urban population of the state (89% of the state's birth population). For group-level variables, the corresponding ORs were 1.12 (1.07-1.18), 1.23 (1.02-1.47), and 1.13 (1.07-1.18). The results of this study suggest that residential exposure to airborne polycyclic organic matter (POM) is associated with increased prevalence of "small for gestational age" births among urban population. Cross-sectional investigations combining air dispersion models with routinely collected population-based health and census data could be a useful approach for identifying the hazardous air pollutants of greatest public health concern.
Adult↗
Comparison of HIV type 1 incidence observed during longitudinal follow-up with incidence estimated by cross-sectional analysis using the BED capture enzyme immunoassay.
The BED capture enzyme immunoassay (BED CEIA) for recent infection was developed for the estimation of HIV-1 incidence in a population from a single cross-sectional survey. To evaluate performance, we applied the assay to specimen sets obtained from a longitudinal cohort study, the AIDSVAX B/B vaccine trial, in which there was an independent and conventional measure of observed incidence. The BED CEIA was performed on specimens obtained during follow-up for seroconversion conducted every 6 months for 3 years. There was excellent agreement between the observed and BED-estimated incidence for all the intervals. The cumulative, annualized incidence observed in the cohort was 3.10 new infections per 100 person-years (95% CI, 2.57-3.63). The corresponding BED-estimated incidence was 2.91 (2.30-3.53). We also estimated the effect of varied prevalence on a fixed incidence. Because some specimens from persons with longer-term infection are classified as recent by the assay, this can inflate the incidence estimate. We quantify this effect and discuss potential mitigation by excluding certain specimens on clinical grounds, by relying on trend differences rather than absolute incidence estimates, by secondary confirmatory testing, or by analytic adjustments for misclassification. Cross-sectional HIV incidence estimation circumvents many of the drawbacks associated with longitudinal cohort studies, but there are test-specific limitations that should be considered in the design of population surveys.
Algorithms↗
Relationship between economic development and suicide mortality: a global cross-sectional analysis in an epidemiological transition perspective by Moniruzzaman and Andersson (Public Health 118 (5), 346-348).
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Cross-Sectional Studies↗
Stages of change for smoking cessation among former problem drinkers: a cross-sectional analysis.
Recent research suggests that problem drinkers are less successful in quitting smoking. Stages of change, decisional balance, and self-efficacy measures were used to assess readiness for smoking cessation in a cross-sectional sample of former problem drinkers who were current smokers. As was expected, a very high percentage of recovering problem drinkers had been or currently were regular smokers. Distributions across the stages of change and relationships between stages and decisional balance in this problem drinker sample was found to be similar to results from more general smoking populations. Of those who had quit both smoking and alcohol, 62% quit drinking before or at the same time as smoking (53% before; 9% simultaneous). Those who quit drinking before or at the same time as smoking were characterized by a more problematic alcohol history. A stages-of-change perspective with this group is discussed, as are new avenues for future research with such populations.
Adult↗
Social deprivation and statin prescribing: a cross-sectional analysis using data from the new UK general practitioner 'Quality and Outcomes Framework'.
We aimed to study the relationship between the prescribing of lipid-lowering medication, social deprivation and other general practice characteristics. We conducted a cross-sectional survey of all general practices in England, 2004-05. For each practice, the following variables were obtained: standardized cost and volume data for lipid-lowering medication, descriptors of general practices, Index of Multiple Deprivation, 2004, ethnicity data from the 2001 Census and Quality and Outcomes Framework data. A regression model was constructed which explained 34.5% of the variation in statin prescribing by general practitioners. The most powerful predictors were higher social deprivation, higher prevalence of coronary heart disease and achievement of cholesterol targets for diabetics. Negative regression coefficients were demonstrated for the proportion of elderly patients in the practice and, to a lesser extent, for the proportion of south Asian and Afro-Caribbean patients. In conclusion, contrary to previous local studies, we found that statin prescribing was higher in more deprived communities, even after adjustment for increased disease prevalence and practice variables associated with deprivation. Statin prescribing was also independently associated with success at achieving cholesterol targets in established disease (secondary prevention). However, our findings suggest under-prescribing of statins to the elderly and possibly also to ethnic minorities.
Adolescent↗
No preventive effect of dietary fiber against colon cancer in the Japanese population: a cross-sectional analysis.
The report of Fuchs et al. in 1999 on the protective effects of dietary fiber (DF) against colon carcinogenesis has led many researchers to question the benefits of DF. We analyzed the relationship between dietary intake and mortality from colon cancer in Japan cross-sectionally. Dietary data were taken from the National Nutrition Survey. The standardized mortality ratio (SMR) was calculated using data from "Vital Statistics" and "the Population Census in Japan." Multiple regression analysis (stepwise variable selection method) was performed with the SMR of colon cancer as the objective variable and intake of DF, nutrients, and food groups in 1966 as the explanatory variables. The beta regression coefficient was significantly positive for intakes of fat, protein, and vitamin C and significantly negative for intakes of calcium and vitamin A to the SMR of colon cancer. However, no significant correlation was observed for DF or for any of the various food groups analyzed. In conclusion, our data do not demonstrate any protective effect of DF on colon cancer in subjects with a low fat intake (Japanese subjects), which supports Fuchs' findings in subjects with high fat intake (U.S. subjects).
Colonic Neoplasms↗
Cross-sectional analysis of renal function in black Americans with NIDDM.
Our objective was to define glomerular filtration rate (GFR) and renal plasma flow (RPF) in Black Americans with non-insulin-dependent diabetes mellitus (NIDDM). This was a cross-sectional study of 71 Black NIDDM patients with diagnosed diabetes duration from 1 mo to 21 yr. Hyperglycemia was regulated and stabilized before patients were entered into the study. GFR and RPF were determined by the clearance of [125I]iothalamate and 131I-labeled hippuran, respectively, with a constant-infusion technique and four urine collection periods. Hyperfiltration, as defined by a GFR of greater than 140 ml.min-1.1.73 m-2, was found in 7 of 20 patients (35%) with newly diagnosed (less than 2 yr duration) NIDDM. The percentage of patients with hyperfiltration decreased with increasing duration of diagnosed diabetes. Decreasing GFR and RPF occurred with increasing duration of diagnosed diabetes. In conclusion, renal hemodynamic changes in Black Americans with NIDDM are similar to those known to occur in White populations with IDDM.
Adult↗
Rise in "no indicated risk" primary caesareans in the United States, 1991-2001: cross sectional analysis.
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Cesarean Section↗