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PubMed2006

Dentinal sensitivity: a natural mineral dietary supplement study.

The purpose of the investigation was to determine the effect of drinking a natural mineral dietary supplement (NMDS) on gingival health and dentinal hypersensitivity. The NMDS product was from a geothermal source and contained 3.6 mg l(-1) of fluoride and other minerals. Sample selection included subjects with gingival inflammation and sensitivity as well as screening for exclusion factors. A double-blind randomized parallel approach was used. The investigation was a quasi-experimental pre/post-test design. The experimental group ingested and swished twice a day with the NMDS (1 l) and the control group followed the same regimen with a placebo containing de-ionized water (DIW). Clinical measurements of gingival inflammation and dentinal sensitivity were taken at baseline, 4 and 8 weeks. Gingival inflammation was measured using the Gingival Index. Dentinal hypersensitivity was measured using a tactile stimulus and an evaporative stimulus. After each stimulus was applied, the subjects rated the amount of discomfort on a visual analogue scale from 0 to 10. Each set of data was analysed using anova and a post hoc probing technique to determine within- and between-group differences (P = 0.05). The experimental and control groups (n = 70) experienced a statistically significant decrease in tactile and evaporative sensitivity scores over time; however, the between-group differences were not significant. The gingival inflammation data were not statistically significant with regard to the within- and between-group differences. Therefore the NMDS and DIW were equally effective in reducing dentinal hypersensitivity and neither product effectively reduced gingival inflammation.

Adult↗
PubMed1982

Morphological research on the sensitivity of dentin.

In order to elucidate the mechanism of dentin sensitivity, the ultrastructure, distribution and organization of nerve fibers in the pulpodentinal border zone in the teeth of young human subjects were investigated by means of silver impregnation and electron microscopy. The nerve fibers in this zone were classified into four types by the location of their terminals and pattern of their ramification: the marginal pulpal nerve fibers, the simple predentinal nerve fibers, the complex predentinal nerve fibers and the dentinal nerve fibers. The nerve fibers reached no further than 100 microns from the odontoblast-predentinal border. The nerve fibers terminated exclusively as free endings, and they were thought to conduct the sense of pain from the corresponding zone. The endings of the predentinal or dentinal nerve fibers were mostly located adjacent to the odontoblastic processes, and this appeared to be a reasonable position for these endings to actively receive the changes in the shape of the processes. The odontoblastic process and the nerve ending associated with it can be considered to be functionally a mechanoreceptive complex. In this sense these free nerve endings might be placed in a group different from the free nerve endings in the inner pulp. The mechanoreceptive complex probably plays a central role in the mechanism of dentin sensitivity. It is suggested that stimuli to dentin first produce the deformation or movement of the odontoblastic processes; these mechanical changes are transmitted to the nerve endings, and the dentin sensitivity occurs.

Axons↗