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At least 91 records · Page 5Linked to original sources
PubMed1997

Disinhibited personality and sensitivity to alcohol reinforcement: independent correlates of drinking behavior in sons of alcoholics.

Thirty nonalcoholic young (18 to 30 years) males with extensive multigenerational family histories of male alcoholism and 29 age-matched, family history-negative controls completed a variety of trait personality questionnaires, participated in a competitive stress task (while sober and alcohol-intoxicated), and were assessed for self-report and laboratory drinking behavior. Low academic achievement, disinhibited personality (as measured by the P Scale of the Eysenck Personality Questionnaire), and sensitivity to alcohol reinforcement were significant and powerful independent predictors of self-report (approximate R2 = 0.40, p < 0.0001) and laboratory (approximate R2 = 0.20, p < 0.0001) drinking behavior. There seemed to be some specificity with respect to the facets of drinking behavior accounted for by each independent variable: low academic achievement and sensitivity to alcohol reinforcement were more related to quantity of alcohol consumption and frequency of excessive consumption, whereas psychoticism was more related to self-reported negative consequences with alcohol. A cluster analysis on three identified correlates of drinking behavior indicated that the two experimental groups could be more accurately subdivided into three homogeneous types. Multigenerational family history males were disproportionately represented in two of these groups: one characterized by enhanced sensitivity to alcohol reinforcement and the other characterized by high psychoticism scores and alcohol-related problems.

Adolescent↗
PubMed1990

Relationships among measures of alcohol drinking behavior, life-events and perceived stress.

Two measures of stress (life-events and perceived stress) and a measure of alcohol-drinking behavior were administered to 6,747 adult males. Analysis was carried out to examine the extent to which subjects classified into drinking-behavior groups differed on stress measures while controlling for age, income, and race. Significant differences held up under age, race, and income controls for life-events and perceived stress between the abstinence, common-use, and problem-drinking groups. Stress scores increased sequentially across the drinking-behavior groups. Apparently, men who are life-long abstainers (teetotallers) experience fewer life-events and perceive less stress than moderate drinkers, while moderate drinkers experience less stress than heavy drinkers.

Adaptation, Psychological↗
PubMed1999

Drinking perceptions and drinking behaviors among urban black adolescents.

PURPOSE: To improve understanding of black (African American and Haitian Blacks) adolescents' drinking behaviors and sexual patterns that put them at risk for human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) to determine whether specific cultural differences affect beliefs and behaviors about alcohol use. METHODS: The study used ethnographic interviewing to provide information about the alcohol norms, beliefs, context, and behavior of African-American and Haitian adolescents. Ethnographic open-ended interviews were conducted with 314 students: 116 African American adolescents (50 boys and 66 girls) and 198 Haitian adolescents (93 boys and 105 girls) in inner-city public high schools. RESULTS: The majority of adolescents had drunk alcohol, and African-American boys and Haitian boys and girls were most likely to report general drinking experience. Both ethnic groups distinguished between negative and positive nonnormative behaviors resulting from drinking beyond and within the boundary of one's limits. African-American boys in particular described not drinking beyond the boundary, to maintain control of their actions. Drinking within the boundary and feeling "relaxed" was endorsed by African American youths, as it was by Haitian youths who felt "normal" and/or viewed drinking certain alcoholic beverages as normative and culturally sanctioned. CONCLUSION: The study suggests there are cultural differences in the constructs of the meaning of drink and drinking that may influence alcohol use. Understanding these differences will improve efforts to impact the drinking behaviors of adolescents by recognizing the drinking socialization, normative drinking patterns, and culturally sanctioned drinking behaviors that may influence alcohol use in different ethnic groups.

Adolescent↗
PubMed1995

The Obsessive Compulsive Drinking Scale: a self-rated instrument for the quantification of thoughts about alcohol and drinking behavior.

It has been suggested that a crucial dimension of alcohol "craving" includes the concept of both obsessive thoughts about alcohol use and compulsive behaviors toward drinking. An interview-based rating scale, the Yale-Brown Obsessive Compulsive Scale-heavy drinkers (YBOCS-hd), has been found useful in quantifying this concept in alcohol-dependent individuals. A self-rating scale, the Obsessive Compulsive Drinking Scale (OCDS) has been developed by us as a modification of the YBOCS-hd. The YBOCS-hd showed excellent interrater reliability in our hands. The correlation between the YBOCS-hd and the OCDS total scores obtained on 60 alcohol-dependent individuals was 0.83. The test-retest correlation for the OCDS total score was 0.96, and the obsessive and compulsive subscales test-retest correlations were 0.94 and 0.86, respectively. The internal consistency of the items in the OCDS was high (0.86) and did not improve significantly with removal of individual items. The shared variance between the OCDS scores and alcohol consumption during the period of evaluation was only approximately 20%, indicating that the dimension measured by the scale was somewhat independent of actual drinking. As such, it might act as an independent measure of the "state of illness" for alcohol-dependent individuals. When used during a prospective 12-week treatment research study, initial results indicate that the OCDS seems to validly measure a dimension of alcohol dependence, because it decreased from baseline during alcohol reduction and increased in relationship to relapse drinking.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1999

Reciprocal relations between stressors and drinking behavior: a three-wave panel study of late middle-aged and older women and men.

AIM: To examine reciprocal relations between stressors and drinking behavior among late-middle-aged and older women and men. DESIGN, SETTING, AND PARTICIPANTS: A community sample of 621 women and 941 men (mean age = 61) provided information about their life stressors and drinking behavior at three times: initial assessment, 1 year later and 4 years later. Structural equation modeling with manifest variables was used to examine cross-temporal relations between stressors and drinking behavior. FINDINGS: Stressors did not predict heavier or more frequent drinking. In fact, among women, increased health stressors predicted a reduction of alcohol consumption; among men, increased financial stressors suppressed alcohol consumption. Higher stressor levels in some life domains did foreshadow later drinking problems. More initial drinking problems resulted in more subsequent financial and spouse stressors for both women and men. Contrary to expectation, more frequent alcohol consumption presaged fewer negative life events, health stressors, and financial stressors for women, and fewer health stressors for men. CONCLUSIONS: The findings suggest that among older adults there may be a harmful feedback cycle whereby problematic drinking and life stressors exacerbate each other, but also a benign feedback cycle in which moderate alcohol consumption and life stressors reduce each other.

Age Factors↗
PubMed1989

Characteristics of circadian rhythm of wheel-running activity and drinking behavior in Mongolian gerbils.

Circadian patterns of wheel-running activity and drinking behavior of Mongolian gerbils were investigated under a 24-h light-dark cycle (LD, 12: 12). Although the circadian pattern of drinking behavior was less clear than that of the wheel-running activity, the two behaviors tended to alter in parallel with each other in 5 out of 10 gerbils. However, the other 5 gerbils exhibited less synchronization between these circadian patterns. Furthermore, there were marked individual differences in the gerbils' circadian patterns, demonstrating not only nocturnal, boundary (showing a peak around the time-of-day of the changing from light period to dark period), and/or diurnal patterns, but also a free-running pattern during the observation period of 79 days. The present result may be due to behavioral characteristics that indicate the gerbils may still be wild type. It is therefore important to know behavioral characteristics of Mongolian gerbils in preclinical evaluation of psychotropic drugs.

Animals↗
PubMedDate not supplied

[An attempt at the objective evaluation of systems quanta in the drinking behavior of rats].

The system architectonics of "systemoquanta" of rat drinking behavior was objectively evaluated in the dynamic process of its formation by means of studying intermediate and final results. The developed experimental equipment made it possible to determine characteristic features of formation and realization of drinking "systemoquanta" and the dynamics of their internal structure. Various "strategies" of system organization of identical behavior were revealed in rats of different groups. The revealed peculiarities of the internal structure of "systemoquanta" in rats of different groups are probably determined by the innate individual differences in the processes of prediction and estimation of intermediate and final results in the framework of strategic "systemoquantum" of drinking behavior.

Animals↗
PubMed1997

Opposite effects of Ro 15-4513 on acquisition and maintenance of ethanol drinking behavior in male Wistar rats.

Acute treatment with Ro 15-4513, a benzodiazepine receptor inverse agonist, has been consistently shown to suppress ethanol self administration behavior by rats. The aim of the present study was to examine the effect of Ro 15-4513 on the acquisition and maintenance of ethanol drinking behavior in male Wistar rats. In rats maintained on a limited access procedure with a choice of 12% w/v ethanol solution and water, acute treatment with Ro 15-4513 (0.1 to 3.0 mg/kg) suppressed ethanol intake in a selective and dose-related manner (p < 0.01). However, by the fourth day of chronic Ro 15-4513 treatment, ethanol intake had returned to baseline levels. In contrast, chronic administration of Ro 15-4513 during the acquisition phase increased ethanol drinking behavior, compared with vehicle (p < 0.05). To assess whether the effects of Ro 15-4513 on ethanol intake were due to an alteration in ethanol kinetics or on behavior, blood ethanol levels and rat social interaction behavior were also assessed. Neither acute nor chronic Ro 15-4513 treatment significantly altered ethanol kinetics after oral administration of ethanol (1.0 g/kg), but did suppress locomotor activity and time spent engaged in active social interaction at the 1.0 and 3.0 mg/kg doses. These results show that Ro 15-4513 has opposite effects on ethanol consumption during the acquisition and maintenance phases of ethanol drinking behavior, suggesting that different mechanisms regulate Ro 15-4513's effects on acquisition and maintenance of ethanol intake. Ro 15-4513's reported anxiogenic or memory enhancing properties may be responsible for its effects on acquisition.

Alcohol Drinking↗
PubMed1992

[Effect of atrial natriuretic peptide on angiotensin II--and water deprivation-induced drinking behavior in rats].

Atrial natriuretic peptide (ANP) present in the brain has been reported to have profound effects on water and salt metabolism. This study was designed to observe the effect of intracerebroventricular (ICV) injection of ANP on drinking behavior of rats, induced by centrally administered angiotensin II (Ang II) and 24-hours water deprivation, by using a T-maze to measure the speed they ran in a runway for water rewards. In 24-hours water deprived rats ICV injection of ANP resulted in a significant decrease of either running speed or water intake. Drinking behavior induced by ICV injection of Ang II in normally hydrated rats was also significantly inhibited by a prior injection of ANP. These findings suggest that ANP in the brain plays an important role in the central control of drinking behavior.

Angiotensin II↗
PubMed1995

Activity of neurons in the lateral preoptic area during drinking behavior by the rat.

Rats were trained to drink water, sucrose solution, and saline while their heads were painlessly held in a stereotaxic apparatus with an attachment fixed to the skull. A total of 286 neurons in the lateral preoptic area (LPO) were recorded during the drinking behavior. During water intake, 40% of the neurons tested were either excited or inhibited. Sucrose elicited responses in 25% of the neurons, and saline in 34%. Of the 52 neurons recorded while rats drank all test solutions, 8 specifically responded to water, 3 were sucrose specific, 4 were saline specific, 12 responded to all solutions, and the remaining 25 did not respond to any solutions. Artificial cerebrospinal fluids (ACSFs) with physiologically hypertonic (+30 mOsm/kg, by NaCl or mannitol) and hypotonic (-30 mOsm/kg) osmotic pressure were applied to 88 neurons through a multibarrel micropipette. Of these neurons, 15 (17%) were hypotonic-sensitive; they were excited by hypotonic ACSF and/or inhibited by hypertonic ACSFs. There were 4 (5%) that were hypertonic-sensitive; they were excited by hypertonic ACSFs and/or inhibited by hypotonic ACSF. Of six hypotonic-sensitive neurons examined, three were water specific, and none were sucrose nor saline specific. Of four hypertonic-sensitive neurons, one was water specific, and another was saline specific. These results showed activity of some LPO neurons specifically related to water intake. Osmosensitive neurons in the LPO may regulate water intake.

Action Potentials↗
PubMed1987

Strain differences in circadian drinking behaviors of ethanol and water in rats.

Voluntary drinking responses to an alternating three-bottle, two-choice paradigm to tap water or to 5% ethanol were measured in adult male Fisher (Fshr; N = 14) and spontaneously hypertensive (SP; N = 16) rats for 6-9 days. All animals were singly caged and housed separately in isolation chambers. The animals received light from 0600 to 1800 (CST) daily (LD 12:12) or remained in constant darkness (DD) at room temperature (23 degrees C). Food was freely available. Water and ethanol bottles were changed daily, and volumes of the respective fluids consumed by each rat were measured. A dim red light (approximately 0.5 lux) was used in handling animals in the dark. SP rats demonstrated significant (P less than 0.05) circadian drinking patterns of water and ethanol consumption under LD and DD lighting conditions. Fshr rats, however, exhibited a circadian pattern (P less than 0.02) only with regard to water consumption under an LD 12:12 lighting schedule; they did not exhibit circadian patterns of drinking water (P less than 0.054) in DD or ethanol in LD (P less than 0.24) or in DD (P less than 0.67) conditions. Volumes of ethanol consumption were also greater (P less than 0.05) in SP rats than in Fshr rats. It is concluded that differences exist in circadian drinking behaviors for both water and ethanol intake in two strains of rats. Perhaps variation in circadian patterns is an evolutionary mechanism that programs behavior over an appropriate time span for differences in physiological needs of nocturnal animals.(ABSTRACT TRUNCATED AT 250 WORDS)

Alcohol Drinking↗
PubMed1993

Reliability of sibling reports on parental drinking behaviors.

Questionnaire data from the Colorado Alcohol Research on Twins and Adoptees (CARTA) were analyzed to explore the reliability of sibling responses to items from the CARTA Family Alcoholism History Questionnaire (FHQ) concerning parental drinking behaviors. Subjects included 142 pairs of male and female, twin and nontwin siblings who reported on paternal and maternal problem drinking. FHQ items were summed to produce drinking-problem scales for fathers and mothers. There was generally good concordance across sibling reports of parental problem-drinking symptoms. There was a significant gender difference in that male offspring were more in agreement about their mothers' drinking behavior, while female offspring were more in agreement about their fathers' drinking behavior. For the most part, objective items, such as having two or more drunk-driving arrests, were more reliable (paternal kappa total = .56, maternal = .66) than subjective items, such as being happy only when drinking (paternal = .24, maternal = -.03). This evidence for reliability of sibling reports about parental drinking does seem to validate the use of such questionnaire data in alcohol studies.

Adoption↗
PubMed1989

[Epidemiological research on drinking of women. (Part 2). Effects of consciousness or attitude concerning about drinking and life events on drinking behavior].

Women drinkers are on the increase, in recent 20 years, according to greater participation of women in public affairs and the change of life style and so on. So, the consciousness or attitude of drinking or alcoholic beverages among women have been changed by the new customs of drinking. In this paper the relationship between women drinking behavior and their consciousness of drinking or life events, was investigated statistically using the data of sending questionnaires concerning about drinking behavior, consciousness and drinking history in Kusatsu city. The subject of investigation was 4,105 women who were aged 30 years and more, and 1,650 answers were available. Then the following findings were obtained; 1) The pattern of consumption of alcoholic beverages changed fairly from 1960, but in recent years, it seems to keep balance and yearly consumption of pure alcohol per adult has leveled off about 8 l. 2) Distribution of PAC (Pure Alcohol Consumption per year) of women exceeding the limit of a liter per year was against the logarithmic normal curve. The median value of PAC of women in Kusatsu was estimated about 0.55 l, and it seemed to be smaller than that of men. QFI (Quantity-Frequency Index) of women was large among those who were full-time workers being in their thirties and forties, and had mother of regular drinker who drank once and more a week. 3) The estimated ratio of excessive drinkers among women by adopting Ledermann's model was larger than the practical ratio. For estimating the women excessive drinkers accurately, it is necessary to use exact P.A.C. of women. 4) The 20 opinions concerning with drinking or alcoholic beverages were grouped into four basic consciousness by using the method of factor analysis. The 1st was 'necessity or values' of drinking, the 2nd was 'method or manner' for taking the pleasure of drinking and of correct drinking, the 3rd was 'regulation' of alcoholic slot machine, minor drinking or drunk and the 4th was 'harmfulness' of alcohol. The 'necessity' promoted drinking and the 'method' also promoted correct drinking but controlled QFI. The 'regulation' was common to all of women and the 'harmfulness' controlled drinking. 5) The life events, for women, such as entrance into a school of higher grade, employment, social activities, divorce, reemployment promoted drinking of women. And retirement, child birth, serious illness controlled drinking of women. Marriage promoted drinking when her husband was regular drinker or when she was infrequent or light drinker before marriage.(ABSTRACT TRUNCATED AT 400 WORDS)

Adult↗
PubMed1984

Circadian rhythms and patterns of running-wheel activity, feeding and drinking behaviors of old male rats.

Running-wheel activity of 7 young adult male rats (3 to 6.5 months of age) and 11 old male rats (22 to 34 months of age), feeding behavior of 10 each of young adult and old male rats and drinking behavior of 6 each of young adult and old male rats were recorded. Circadian rhythms were lost in 2, 6 and 1 old rats respectively in running activity, feeding and drinking behaviors. Loss of circadian rhythm of three behaviors seems not to occur concomitantly. Although the remaining old rats still showed as high a percentage of nocturnal activities in these three behaviors as young rats, the patterns of the behaviors revealed age-related changes. Old rats had decreased daily activity with small numbers and short duration of bursts of activity. Total frequencies of the head of rats interrupting the photobeam of a feeder during 24 hour period increased in old age with patterns of a small number of long meals with a rapid ingestion rate. Total numbers of licking the spout per day increased in old rats with patterns of a small number of short duration draft with a rapid licking rate. Old rats still maintained diurnal difference of drinking-to-feeding ratio. The similarity of the feeding and drinking patterns between old male rats and ventromedial hypothalamus lesioned rats was discussed.

Aging↗
PubMed2026

Water intake, switching between bites and sips, and drinking behavior are associated with food intake across meals varying in spiciness: A secondary analysis of two randomized crossover studies.

Widespread nutrition advice instructs consumers to drink water with meals to increase fullness and reduce energy intake. However, recent data indicates greater water intake is associated with more food intake at a meal, not less. Switching between meal components (e.g., alternating between food and water), has also been associated with increased food intake at a pasta meal, but it remains unclear whether this applies to other foods. In a secondary analysis, we pooled existing data from 2 crossover experiments (total n&#xa0;=&#xa0;86) where adults ate an ad libitum lunch consisting of 650&#xa0;g of beef chili (n&#xa0;=&#xa0;52) or chicken tikka masala (n&#xa0;=&#xa0;34) with 450&#xa0;g of water twice in the laboratory while being video-recorded. For both experiments, the spiciness of the lunch was varied by adding different ratios of hot:sweet paprika. Videos were coded to measure sip number, sip size (g/sip), drinking rate (g/min), and number of switches between bites of food and sips of water. As we previously reported, increasing spiciness slowed eating rate and reduced food intake; in secondary analyses described here, the reduction in food intake was not moderated by water intake, switching, or drinking behaviors (all p&#xa0;>&#xa0;0.73). Notably, across all meals, greater water intake (p&#xa0;<&#xa0;0.001) and switching (p&#xa0;=&#xa0;0.02) associated with greater food intake. Overall, individuals ate more when they drank more and switched between bites and sips more often, highlighting the potential influence of water and drinking behaviors on food consumption. This finding challenges the widespread dietary advice to drink water with meals to reduce food intake.

Humans↗
PubMed1979

Role of central catecholamines in the control of blood pressure and drinking behavior.

The role of central nervous system (CNS) catecholamines in the development of hypertension and the control of drinking behavior was assessed in rats by depleting these amines with 6-hydroxydopamine (6-OHDA). Intraventricular administration of 6-OHDA completely prevented the development of one-kidney renal hypertension and abolished the associated increase in water consumption. 6-OHDA-treated rats showed deficits in drinking behavior when challenged with subcutaneous injections of angiotensin II (AII) and hypertonic sodium chloride. The acute pressor responses produced by intraventricular injections of AII and carbachol were virtually abolished by central catecholamine depletion. However, drinking produced by central cholinergic stimulation remained intact while AII drinking was significantly reduced. These data demonstrate that the integrity of CNS catecholamines is required for the development of one-kidney renal hypertension and the increased drinking which accompanies it. In addition, destruction of central catecholamine-containing neurons allows for a specific dissociation of the pressor and drinking responses produced by central cholinergic but not AII stimulation.

Animals↗