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PubMed1985

Filing and retrieving a personal collection of 35-mm teaching slides in medicine. A simplified system.

The use of 35-mm slides to teach or supplement lectures has become an important technique in medical education. To be effective, the slide collections need an efficient filing and retrieval system. The systems previously described for filing and retrieval of slides usually are expensive, require many materials and much space, and are more suited for slide libraries and large collections than for personal collections of teaching slides. A more simple and inexpensive system to file and retrieve personal collections of 35-mm teaching slides uses color labels to identify groups of topics and also numbers to identify each slide in a given group. The color labels also help in proper loading of slides into the slide tray. This system can be expanded easily to suit individual needs.

Audiovisual Aids↗

PubMedDate not supplied

Reporting, filing, and retrieval of coronary angiographic findings: a new personal computer-based system.

A software system for semiautomatic reporting and automatic filing of coronary angiographies has been developed and is suitable for an IBM Personal Computer (PC) with graphic tablet and printer. Coronary angiographic findings referring to the native anatomy, pathology, and post-surgical status can be easily recorded. The data is automatically coded and filed according to category of information. This system can analyze previously filed data and perform searches under one or more angiographic findings. This allows for a comparison of different series of patients.

Algorithms↗

PubMed1988

Microcomputer-assisted filing system of cardiac catheterization records using a relational database management system.

To efficiently store and retrieve cardiac catheterization records, we have developed a computer-assisted database, which comprises a 16-bit microcomputer with dual floppy disk drives, a 20 MB random-access memory, hard disk drive, and a line printer. All programmings were accomplished using a relational database management system (R:base 5000, Microrim, Inc.). Data inquiry procedures could be performed with direct operational commands of the system as well as with preprogrammed command files, and final results of searches were printed out with a line printer. The major advantages of the present system described in this report include: (1) the relatively easy and rapid creation of the database, (2) ease of modification of the database structures even after the system design is finished, (3) operational commands in combination with conditional operator(s) are flexible and powerful enough to allow the end user to retrieve data based on various kinds of criteria, (4) a high-level programming language provided by the R:base automates a series of database procedures with relative ease, (5) relational capabilities of the database management system can enhance the possibility of reconstruction of a new data file from a single or several preexisting data files, and (6) the system can be realized at reasonable cost.

Cardiac Catheterization↗

PubMed1991

An innovation in flow cytometry data collection and analysis producing a correlated multiple sample analysis in a single file.

The problems associated with rapid analysis and interpretation of data from multicolor immunofluorescence panels have been a formidable barrier to their routine use. Using present flow cytometry concepts, a panel of 11 tubes each containing multiple phenotypic markers or controls requires postdata acquisition manipulation of many multiparameter histogram and listmode files. We have developed a method that compresses all of the information from such a panel into a single listmode data file during run time. A single data file is used to record the entire phenotypic analysis for a particular patient or series within an experiment. This is accomplished by the incorporation of a tube identifier parameter (TIP) as well as the fluorescence and light scatter parameters normally collected. The TIP can then be used for gating discrimination of any tube or set of tubes within a panel. When the TIP is correlated with the PRISM parameter the entire patient phenotypic image can be represented within a single two-parameter histogram we have called a phenogram. This phenogram can be generated in real time, providing on-line preprocessing of a complex multicolor experiment. By examining the image created by the phenogram it is possible to rapidly flag abnormalities such as incorrect gating. This procedure was carried out on an EPICS Elite flow cytometer in its standard configuration with the addition of hardware to provide an input for the TIP.

Data Collection↗

PubMed1981

The gramicidin A channel: a review of its permeability characteristics with special reference to the single-file aspect of transport.

Gramicidin A forms univalent cation-selective channels of approximately 4 A diameter in phospholipid bilayer membranes. The transport of ions and water throughout most of the channel length is by a single-file process; that is, cations and water molecules cannot pass each other within the channel. The implications of this single-file mode of transport for ion movement are considered. In particular, we show that there is no significant electrostatic barrier to ion movement between the energy wells at the two ends of the channel. The rate of ion translocation (e.g., Na+ or Cs+) through the channel between these wells is limited by the necessity for an ion to move six water molecules in single file along with it; this also limits the maximum possible value for channel conductance. At all attainable concentrations of NaCl, the gramicidin A channel never contains more than one sodium ion, whereas even at 0.1 M CsCl, some channels contain two cesium ions. There is no necessity to postulate more than two ion-binding sites in the channel or occupancy of the channel by more than two ions at any time.

Cations, Monovalent↗

PubMed1991

Patch-clamp studies on the anomalous mole fraction effect of the K+ channel in cytoplasmic droplets of Nitella: an attempt to distinguish between a multi-ion single-file pore and an enzyme kinetic model with lazy state.

Patch-clamp studies have been employed in order to check whether the assumption of a multi-ion single-file pore is necessary for the explanation of the anomalous mole fraction effect or whether this effect can also be explained by a single-barrier enzyme kinetic model. Experiments in the cell-attached configuration were done on the tonoplast membrane of cytoplasmic droplets of Nitella in solutions containing 150 mol m-3 of K+ plus Tl+ with seven different K+/Tl+ ratios. At first sight, the results seem to support the multi-ion single-file pore, because apparent open channel conductivity displays the anomalous mole fraction effect, whereas open-probability has not been found to be dependent on the K+/Tl+ ratio. Changes in open probability would be expected for a single-barrier enzyme kinetic model with a lazy state. On the other hand, the lazy-state model is more successful in explaining the measured I-V curves. The entire slope of the apparent open channel current-voltage curves rotates with changing K+/Tl+ ratios in the whole voltage range between -100 and +80 mV. Numerical calculations on the basis of multi-ion single-file pores could create the anomalous mole fraction effect only in a limited voltage range with intersecting I-V curves. The apparent absence of an effect on open probability which is postulated by the lazy-state model can be explained if switching into and out of the lazy state is faster than can be resolved by the temporal resolution of 1 msec.

Biological Transport↗

PubMed1983

Rate theory models for ion transport through rigid pores. II. Time-dependent analysis of the single-file model with special reference to oscillatory behavior.

This article deals with the time-dependent evolution of the single-file movement of ions through channels of both biological and artificial membranes. The single-file transport process may exhibit not only the usual relaxation behaviour but also oscillatory behaviour as a steady state is approached after an initial perturbation. A necessary condition for the occurrence of oscillations is that the system acts sufficiently far from equilibrium. The occurrence of oscillations is due to the interactions within the transport system which are taken into account by the single-file model; these are the electrostatic repulsion between the ions being transported, and the competition of the ions for the free binding sites within the pore. Information about the strength of the interactions can be obtained by measuring the damping of the transport observables (e.g. the electric current): The stronger the inter-ionic repulsion, the more apparent the oscillatory behaviour will become. Furthermore, the damping is influenced by the microscopic structure of the transport system (i.e. the energy profile of the pores). With an increasing degree of microscopicity, i.e. with a decreasing number of binding sites and an increasingly irregular pore profile, the oscillations become more damped. However, a considerable oscillatory behaviour can only be predicted for pores with both a sufficiently regular structure and a sufficiently large number of binding sites. For this class of pores, however, the measurement of the damping represents an appropriate method of gaining information which could exceed that obtainable from the usual methods of measuring stationary quantities (e.g. stationary conductance). Moreover, our goal is to explain theoretically how the oscillatory behaviour can be interpreted in terms of the order inherent in the ionic movement, which is determined by both the external and internal forces and the microscopic properties of the system.

Binding Sites↗

PubMed1991

Radiographic interpretation of endodontic file length.

The purpose of this study was to evaluate the accuracy of examiners when asked to make file length adjustments with only a radiograph. The examiners viewed several radiographs under proper viewing conditions but without the aid of measuring devices. Two files of varying lengths (sizes 10 and 15) were placed in maxillary and mandibular premolars and molars from cadavers. The nine examiners were 67.91% in agreement of actual file length adjustment needed when adjustments of up to 0.5 mm were needed, 17.76% when adjustments of from 0.5 up to 1.0 mm were needed, and 14.33% when adjustments of greater than 1.0 mm were needed.

Dental Pulp Cavity↗

PubMed1989

Electrochemical engineering approach to the irrigation of tooth canals under the influence of a vibrating file.

Doubt exists concerning the irrigation of secondary tooth canals when the vibration of a file introduced into the main root canal is superimposed on flow-through irrigation of the main canal. Depending on the type of commercial equipment used, the vibrations of the file are sonic or ultrasonic. We use the methodology of an electrochemical engineering approach in a study of the intensity of the irrigation of the secondary canals under the influence of sonic and ultrasonic vibrations of a file located at various heights in the main canal. The tooth canals are simulated by small electrochemical cells containing electrodes located at the end of cavities simulating the secondary canals. An electrochemical method is used to measure the mass transfer coefficients at these electrodes, a classical method in electrochemical engineering laboratories. The values of the mass transfer coefficients are representative of the importance of the irrigation of the electrodes. Thus they give a quantitative idea of the vibrations on the irrigation of secondary tooth canals. The work demonstrates the usefulness of the electrochemical engineering approach in contributing to the solution of a biomedical problem.

Electrochemistry↗

PubMedDate not supplied

User discipline in a personal computer-based filing of ultrasound records.

The discipline of entering ultrasound examination data in a personal computer file was studied over two periods. During the first period (19 weeks), the use of the computer was limited to one laboratory. During the second period (14 weeks), the computer was shared by three laboratories operating in nearby premises. During the study, 2857 (89%) of a total of 3209 ultrasound examinations performed were duly recorded in the data file. The frequency of failure to enter data was markedly higher during the second period (7-45%) than during the first period (5%) of the study. Overall, there was a highly significant (p less than 0.001) tendency to enter pathological findings at the expense of normal and non-diagnostic findings. The ease of access to the computer and the number of examinations recorded appear to determine user conscientiousness in filing data. Selection and omission of data impair the usefulness of the data log in research.

Humans↗

PubMed1990

A comparison of techniques for cleaning endodontic files after usage: a quantitative scanning electron microscopic study.

One-hundred ten new endodontic files were used to prepare canals and were then cleaned using three different techniques: (a) gauze soaked with alcohol, (b) sponge soaked with alcohol, and (c) ultrasonic bath. The cleaning ability of each of these techniques immediately after use and after 1 h of delay were compared. Identical areas on each file were examined by using a custom-made jig. Morphometric analysis of debris was carried out using a Bioquant image analysis system. Sponge/alcohol was the worst cleaning method; this was significantly different from the other two techniques. The gauze/alcohol and ultrasonic bath were similar. The 1-h delay before instrument cleaning did not affect the ability of any of the techniques tested. None of the methods tested were able to totally clean the files.

Decontamination↗

PubMed1990

High precision, simulated cutting efficiency measurement of endodontic root canal instruments: influence of file configuration and lubrication.

A high precision method is presented for measurement of root canal instrument cutting efficiency in pure, linear movements. Operator-independent instrumentation is achieved by means of an automatic, mechanical test rig mounted as an accessory in an Instron tensile testing machine. It is now possible to do reliable cutting simulation that closely represents clinical motions. Cutting efficiency is assessed via "wear" volume measurement by means of three-dimensional surface mapping on bovine bone serving as a dentin substitute. A volume precision of 3 x 10(-3) mm3 is achieved which is equivalent to a weight resolution better than 10 micrograms. In particular, cutting efficiency data for K-type and H-type files is presented showing an enhanced performance (by roughly a factor of 3) in the latter case. Lubrication is also shown to increase the cutting efficiency (+200% for the K file and +30% for the H file). Water and 2.5% sodium hypochlorite solutions have equivalent effects.

Animals↗

PubMed1990

Comparison of balanced forces, endosonic, and step-back filing instrumentation techniques: quantification of extruded apical debris.

Randomly assigned groups of 15 single-canal, extracted human teeth were instrumented by one of three techniques: balanced forces, endosonic, or step-back filing. Debris extruded from the apical foramen during instrumentation was collected onto preweighed filters using a suction filtration apparatus. Following desiccation, weight determinations were made on an analytical electrobalance. A one-factor analysis of variance was performed on the debris weight data revealing that the endosonic technique apically extruded significantly more debris than the balanced forces technique (p less than 0.05). Further analysis of the data, excluding debris weights greater than 1 SD from the mean, using a one-factor analysis of variance revealed the balanced forces technique apically extruded significantly less debris than either endosonic or step-back filing techniques (p less than 0.05). No significant difference was demonstrated between endosonic and step-back filing techniques.

Analysis of Variance↗

PubMed1976

Computer printing and filing of microbiology reports. 1. Description of the system.

From March 1974 all reports from this microbiology department have been computer printed and filed. The system was designed to include every medically important microorganism and test. Technicians at the laboratory bench made their results computer-readable using Port-a-punch cards, and specimen details were recorded on paper-tape, allowing the full description of each specimen to appear on the report. A summary form of each microbiology phrase enabled copies of reports to be printed on wide paper with 12 to 18 reports per sheet; such copies, in alphabetical order for one day, and cumulatively for one week were used by staff answering enquiries to the office. This format could also be used for printing allthe reports for one patient. Retrieval of results from the files was easily performed and was useful to medical and laboratory staff and for control-of-infection purposes. The system was written in COBOL and was designed to be as cost-effective as possible without sacrificing accuracy; the cost of a report and its filing was 17-97 pence.

Computers↗

PubMedDate not supplied

An evaluation of data items for the filing system of a gastric cancer screening project.

We have been developing a database for gastric cancer screening test since 1979. People who live in the city area voluntarily undergo the test once a year, and the data of each examinee are stored into the file constituting a record for each visit. Up to the present time, 91 400 records have been entered into the database. The file is supported by FLXFL, an interactive system for programming-free data management and analysis, which runs on a PDP 11/44. A record consists of 56 items, that is: examinee's name, address, telephone number, past history, family history, present complaints, radiographic findings of the gastrointestinal tract and so forth. Data other than X-ray and gastro-camera findings are taken by questionnaire. Using the data in the file, we have statistically analysed whether each data item is useful or not for detecting a patient with gastric cancer. The results of the analyses are presented in this paper.

Adult↗

PubMed1992

[Image filing system for radiotherapy using a video tape recorder].

The compact media of video tape is applied to store medical images with spoken reporting. Video tape recorder (VTR), personal computer, and video/computer interface constitute our image filing system. VTR is controlled automatically by personal computer. Our system enable to file images including moving images, and color images easily, and established cheap and useful image filing system.

Humans↗

PubMed1992

The Social Security Administration's 10-percent sample file of OASDI beneficiaries.

This is another in a series of technical articles describing Social Security Administration sample files and statistical systems. The focus of this article is the 10-percent sample file that provides program and demographic information on Social Security beneficiaries under the Old-Age, Survivors, and Disability Insurance program. The article explains the contents and availability of the 10-percent sample and presents several statistical tabulations as examples of the wide variety of data that can be developed from the file.

Female↗

PubMed1991

Medical malpractice claims filed by Medicaid and non-Medicaid recipients in Maryland.

Several databases available in Maryland are used to investigate whether Medicaid recipients are more likely than other persons to engage in medical malpractice litigation. All malpractice claims filed during 1985 and 1986 (N = 1037) were updated for outcomes through 1989 and described with regard to the payer status of claimants. The proportion of claims filed by persons enrolled in Medicaid before and/or during the alleged malpractice incident was lower than the proportion of state residents enrolled in Medicaid. In addition, the proportion of obstetric claims filed by Medicaid recipients was identical to their proportion of hospital discharges for obstetric services during the period in which the incidents occurred.

Attitude to Health↗