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[Primary dermatoplasty in open injuries of the hand and fingers in ambulatory conditions].

An experience with the treatment of 158 patients with open lesions of hands and fingers under conditions of traumatological unit is described. The authors recommend such operations of skin plasty as plasty by means of translocation of local tissues including insular triangle flaps on a vascular pedicle, free skin plasty, plasty on a temporary feeding pedicle from neighbour finger or hand, plasty after Krasovitov, replantation of not completely torn terminal finger phalanges. Skin plasty operations resulted in shorter terms of treatment and better functional and cosmetic results.

Adult↗

[Open fractures of the fingers in children].

The experience with the treatment of open fractures of finger phalanges in 187 children is presented. The operation technique and curative methods are described for patients with soft tissue defects.

Child↗

[Medical anthropological aspects of hand phalanx dermatoglyphics].

Main and middle phalanx skin patterns represent a polymorphic hereditary system of signs practically not studied in anthropology, but interesting for forensic medicine and criminology from the viewpoint of expert evaluation of relation and personality identification. Based on a vast scope of data (600 hand impressions of 300 subjects from Russian families), a classification of patterns on the main and middle finger phalanges has been developed and their incidence evaluated. The proposed classification includes 15 types and 40 subtypes. The incidence of individual patterns on phalanges of different site and order has been determined. The problem of genetic determination, i.e. inheritance of certain patterns from father and mother, remains open and requires a special research.

Adult↗

[Pachydermatodactyly associated with plantar pachydermy].

INTRODUCTION: Pachydermodactyly is a superficial fibromatosis located on the proximal portion of fingers'phalanges and interphalangeal joints. Several types of this disease have been described depending on topography, etiology and pathological associations. We report a typical observation of pachydermodactyly associated with a plantar pachydermy. CASE-REPORT: A 19 year-old man was followed for a psychotic disease, associated with mental retardation. On clinical examination, he showed a typical pachydermodactyly, predominantly located on the second, third and fourth fingers of both hands, associated with recent acrocyanosis. A pachydermic aspect was also observed on the external part of the feet sole. Histopathological analysis was identical on digital and plantar lesions with collagen swelling. These lesions extended into the subcutaneous fat only in the feet. DISCUSSION: This observation is compatible with the most classical form of pachydermodactyly which involves several fingers of both hands, usually in men. Furthermore, the association with a psychiatric disorder and the notion of repeated traumatisms have been frequently reported in the literature. However, acrocyanosis and the important disability observed in our case are unusual. Association with plantar pachydermy has never been reported. The identical histological aspect on finger and feet sole suggests that pachydermatodactyly should be integrated in framework of acral pachydermy.

Adult↗

Characterization of the integrity of three-dimensional trabecular bone microstructure by connectivity and shape analysis using high-resolution magnetic resonance imaging in vivo.

Bone mineral density and bone structure are the main determinants of bone strength in osteoporosis. In this study we used high-resolution magnetic resonance imaging to visualize the bone microstructure in the finger phalanges in vivo and to assess the topological three-dimensional connectivity of the trabecular network and the shape of the trabeculae as measures of bone quality. We visualized the phalanges of young and elderly healthy volunteers in vivo with a spatial resolution of 152 microm x 152 microm x 280 microm. Image processing software to quantify three measures of connectedness was developed and tested: connectivity, global connectivity density, and local connectivity density. Global three-dimensional connectivity ranged from 904 to 1,607 connections. Global connectivity density ranged from 2.9 to 4.7 connections per mm with large intersubject differences. We found a decrease of local connectivity density with growing distance from the joint ranging from 5.1 to 0.2 connections per mm. These preliminary results represent a quantitative description of the well-known rarefication of the trabecular network when moving from epiphysis to the diaphysis. Three-dimensional visualization showed a dense network consisting mostly of rod-like trabeculae at the epiphysis changing to a less dense network of a few plate-like structures near the medullary canal. An algorithm for the quantitative classification of trabecular architecture with regard to plate or rod-like shape was tested for feasibility. We conclude that in vivo assessment of three-dimensional properties of the trabecular network is possible in human phalanges. Determination of connectivity and shape will allow quantification of structural aspects of osteoporotic changes and may improve assessment of fracture risk.

Adult↗

Discriminatory ability of magnetic resonance T2* measurements in a sample of postmenopausal women with low-energy fractures: a comparison with phalangeal speed of sound and dual x-ray absorptiometry.

RATIONALE AND OBJECTIVES: We sought to assess the ability of magnetic resonance T2* measurements to discriminate between patients with and without osteoporotic fracture and compare the results with the discriminatory ability of speed of sound (SOS) measured at the phalanx and axial bone mineral density (BMD). MATERIALS AND METHODS: T2* measurements of lumbar spine were obtained at 1.5 T in 26 postmenopausal women with osteoporotic fractures and 28 age-matched healthy control subjects. A multiecho gradient echo (MEGRE) pulse train sequence was used with echo times of 2.70-74.93 milliseconds using 2.33-millisecond interecho intervals. BMD measurements were made in the axial skeleton. SOS also was measured at the finger phalanges. RESULTS: The in vivo short-term reproducibility for T2* was 1.85%. T2*, spinal BMD, total hip BMD, and SOS measurements were found to give comparable discrimination between normal and osteoporotic women with odds ratios of 2.6, 2.6, 3.2, and 2.2, respectively. CONCLUSIONS: T2* measurements of lumbar spine are reproducible and capable of differentiating between postmenopausal women with and those without osteoporotic fractures.

Absorptiometry, Photon↗

The conservative management of fractures of the shafts of the phalanges of the fingers by combined traction-splintage.

Recent publications discussing fractures of the shafts of the phalanges of the fingers discount their management by traction because of possible complications and difficulties of application. A technique using splintage combined with isometric skin traction, used for many years in Southampton, has proved effective and free of complications. The results of the treatment of eighteen consecutive appropriate fractures using this technique are discussed.

Finger Injuries↗

Combined chemotherapy and teratogenicity.

BACKGROUND: The concomitant occurrence of breast cancer and pregnancy is relatively uncommon. We report the case of a patient with syndactyly, cleft hands, and absence of distal finger phalanges associated with maternal exposure to chemotherapeutic agents during the first trimester of pregnancy. These associations have not been previously described. CASE: The patient was born by normal delivery after 38 weeks of pregnancy. His mother became pregnant while receiving chemotherapy (cyclophosphamide, 5-fluorouracil, and adriamycin) for breast cancer, and the fetus was exposed to these drugs from conception to the 16th week of pregnancy. At birth, anomalies were observed, including a high-arched palate, microcephaly, a flat nasal bridge, bilateral syndactyly in the first and second fingers with a hand cleft between the second and third fingers and hypoplasia of the fifth fingers, and dystrophic nail of the fourth finger of the left hand. The patient's growth and development were deficient. CONCLUSIONS: The malformations associated with in utero exposure to these chemotherapeutic agents are highly variable, but growth deficiency and anomalies of the craniofacial region and limbs are the most common. The pattern of malformations in children who were congenitally exposed to chemotherapeutic agents appears to be directly related to the age at and duration of exposure, rather than to the specific drug itself. Effective contraception is essential for the safe use of a potential teratogen in nonpregnant women of reproductive age.

Abnormalities, Drug-Induced↗

The mode of progression of subperiosteal resorption in the hyperparathyroidism of chronic renal failure.

Subperiosteal resorption in finger phalanges is usually thought to be the result of osteoclastic bone resorption on the periosteal surface of bone, progressive centripetally, with creation of the serrated appearances and "lace-like" patterns in periosteal cortical bone. Our longitudinal microradioscopic observations in patients with secondary hyperparathyroidism of chronic renal failure have revealed evidence of another pathogenetic mechanism: by the enlargement of intracortical juxtaperiosteal resorption spaces, the remaining thin layer of bone is broken down from inside the bone, i.e., a centrifugal rather than centripetal process.

Adult↗

Fractures of the hand associated with riding the mechanical bull.

Presented are the cases of four patients who sustained similar dominant hand injuries while riding a mechanical bull apparatus. The injuries included fractures of the second metacarpals as well as of the index finger phalanges. The mechanism of injury in each case occurred not from striking or catching the injured hand on the bull or by falling off the apparatus, but secondary to the extreme torque forces applied to the extremity during the severe gyrations.

Adult↗

Infection after fingertip injury in children.

We describe two cases of severe infectious complications after trauma to the finger phalanges in children: osteoarticular infection of the thumb and phlegmon of the thumb's long flexor sheath. These complications are rare after such injuries, which are common and for which the appropriate treatment is often an issue.

Antibiotic Prophylaxis↗

The tale of a nail sign in chromosome 4q34 deletion syndrome.

Relatively, few reports of deletions involving the distal long arm of chromosome 4 (4q) exist. Five further cases are described and the findings are compared with those in previous literature reports. Distal 4q deletions may be recognized by the distinctive appearance of the fifth finger, which is stiff with a hypoplastic distal phalanx and a hooked or volar nail. All cases with this characteristic fifth finger anomaly appear to have deletions involving 4q34.

Abnormalities, Multiple↗