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PubMedDate not supplied

Nonoperative management of pediatric type I open fractures.

The purpose of this study was to examine the results of pediatric patients with type I open fractures managed nonoperatively. A retrospective chart review of all type I open fractures managed nonoperatively from 1998 to 2003 was performed. Forty patients were followed until healing of the fracture clinically and radiologically. One deep infection occurred in this series, producing an overall infection rate of 2.5%. This compares favorably with the literature's infection rate of 1.9% in pediatric type I open fractures treated operatively. There was a 0% infection rate in the 32 upper-extremity type I open fractures and a 0% infection rate in the 23 patients under age 12. These results suggest that nonoperative management of pediatric type I open fractures is safe and effective, especially in children under age 12 with upper-extremity fractures.

Adolescent↗
PubMed1992

Clinical experience with unreamed locked nails for open tibial fractures.

Open fractures of the tibia remain a formidable injury. External fixation has been the mainstay of treatment for the more severe fractures. This treatment option, however, is not without significant complications. Of particular importance is the rate of infection once the fixator is converted to a reamed intramedullary nail in cases of delayed union or nonunion. A retrospective review of the records of 20 patients who underwent unreamed, interlocked, intramedullary nailing for tibial fracture has shown that unreamed tibial rodding offers an excellent alternative to external fixation for the management of Grades I and II open tibial fractures. Additionally, for Grade III open fractures, this serves as an excellent form of preliminary stabilization, allowing the soft-tissue injury to heal.

Adolescent↗
PubMed1997

[Treatment of open fractures due to dog bite].

2 patients aged 12 and 19, respectively, sustained open fractures of the wrists due to dog bites. Both were bitten on a wrist by Rotweiller dogs, but with different magnitudes of injury to bone and soft tissue. Treatment, clinical course and recovery are described, together with recommendations for dealing with open fractures due to animal bites. In the presence of considerable injury to soft tissue and bone, and of exposure to canine oral flora, open fractures due to dog bites should be dealt with as high grade open fractures.

Adolescent↗
PubMed1975

[Current problems in the treatment of open fractures].

The paper evidently does not discuss several important problems of the management of open fractures, but it is confined to the exposition of some fundamental rules of their traitment. Nowadays, the treatment of open fractures is to be decided individually for all cases. A great number of patients with open fracture owe their recovery to the proper first aid care at scence of accident. This is also in respect of the further treatment in the hospital of great importance. Exagerated activity is usually superfluous in the treatment of open fractures. Less and more proper management is often more useful for the injured patient.

Bone Plates↗
PubMed1994

[Optimal timing of wound closure in severe open fractures with temporary coverage by skin substitute].

In a consecutive series of 1085 open fractures treated at the University of Louisville Level I Trauma Center from May 1983 to July 1992, 381 severe compound fractures in 335 patients were managed with the antibiotic bead pouch technique. There were 27 grade I (marked swelling, compartment syndrome), 115 grade II and 239 grade III open fractures (94 type IIIA, 114 type IIIB and 31 type IIIC). These fractures were managed with early administration of broad spectrum antibiotics, copious wound irrigation, serial debridements and external skeletal stabilization. Tobramycin-PMMA-beads were placed in the wound and porous plastic film (Opsite) covered the soft tissue defect. This dressing was changed every 48 to 72 hours until wound coverage/closure could be obtained. Infection rate either on an acute or chronic basis was 2.6% in grade II open fractures and 8.4% in grade III compound fractures. There was no infected wound or bone in the grade I category. Those fractures which did not develop an infection were closed at a mean time of 7.6 days; those which developed an infection were closed at a mean time of 17.9 days. The difference was statistically highly significant (p < 0.001). When severe open fractures are managed with the antibiotic bead pouch technique, wound closure should be obtained within one week to prevent infectious complications.

Adolescent↗
PubMed2000

Emergency management of open fractures and luxations.

This article discusses the emergency management of open fractures and traumatic joint luxations. The emergency management of open fractures can be challenging. The proper initial evaluation and treatment of open fractures can have a positive impact on their successful outcome. The clinical signs and diagnosis of traumatic joint luxations are reviewed. Emphasis is placed on the management of these injuries in the emergency situation.

Animals↗
PubMed1989

Factors influencing infection rate in open fracture wounds.

Seventy-seven infections in 1104 open fracture wounds were evaluated to identify those factors that predisposed to infection. Factors could be placed into three categories: (1) increased risk, (2) no effect, and (3) inconclusive. The single most important factor in reducing the infection rate was the early administration of antibiotics that provide antibacterial activity against both gram-positive and gram-negative microorganisms. In this study, surgical debridement was performed on all open fracture wounds.

Adolescent↗
PubMed1980

Pelvic open fractures.

Thirty-one of 738 patients with pelvic fracture (1970--1978) had open pelvic fractures. Eight per cent of all pelvic fractures due to pedestrian accidents and 12.5% due to motorcycle accidents were open. The mortality for open pelvic fractures was 42% compared with 10.3% for closed pelvic fractures. The open pelvic fracture was the primary or an important secondary cause of death in 85% of patients who died. Major causes of death related to open pelvic fracture are (1) hemorrhage and (2) sepsis and/or renal failure. Major vascular injury is common with open pelvic fracture (19%) and compounds the problem of blood loss. Therapy is directed to blood volume replacement, repair of major vascular injury and to control of diffuse retroperitoneal hemorrhage. Any drainage should be by a closed system. This procedure plus colostomy with perineal, vaginal or rectal injury should decrease septic complications. The high mortality reflects the inadequacy of current methods of treatment of open pelvic fractures.

Adolescent↗
PubMed1989

[External fixation for open fractures of the femur].

32 cases of severe open fractures of the femur were treated by external fixation in 1 lateral plane with either the Wagner apparatus or the A.O. tubular system. 2/3 of the cases were war injuries and 1/3 were due to traffic accidents. In 1 case the broken limb was severely burned. In half the cases external fixation was changed for P.O.P. or internal fixation because of pin tract infection or delayed union. There were no non-unions or amputations, but 1 case had chronic post-traumatic osteomyelitis. We conclude that the method of choice for 3rd degree open fractures of the femur is external fixation. In the case of severe multitrauma and complex wounds with vascular injury or burns, external fixation is mandatory.

Femoral Fractures↗
PubMed1998

Nonreamed flexible locked intramedullary nailing in tibial open fractures.

Thirty-nine open unstable tibial shaft fractures were treated with a nonreamed flexible locked intramedullary nail between 1992 and 1995. There were 23 Grade I, 12 Grade II, three Grade IIIA, and one Grade IIIB fractures. The average time of followup assessment was 24 months. The average time to fracture union was 24 weeks. Complications were related in most cases to fractures with highly unstable patterns and extensive soft tissue lesions. There were five (12.5%) delayed unions and one (2.5%) nonunion. Deep infections developed in three (7.7%) patients. One patient required an additional procedure to correct a varus malunion. There were no implant failures. It was concluded that nonreamed flexible locked nailing provides effective control of axial and rotational stability in unstable Grades I to IIIA open fractures with acceptable union rates and a low incidence of complications secondary to the fixation system.

Adolescent↗
PubMed1992

Teicoplanin in open fractures: a preliminary report.

The occurrence of infection following open fractures varies with the severity of the fracture and associated soft tissue damage. In order to study the effect of antibiotics given prophylactically, teicoplanin has been used in a prospective study. On admission, fractures were graded according to the severity of the tissue damage: Type I--soft tissue injury less than 1 cm Type II--soft tissue injury more than 1 cm. Type III fractures characterized by extensive soft tissue and bone damage were not included in the study. Type I patients were given a single dose of teicoplanin, 400 mg i.v.; Type II patients were given a single dose of teicoplanin, 400 mg i.v., followed by two further intravenous injections at 12 and 24 hours. Patients were assessed for the presence of wound and bone infections and follow up was for 1 year. Preliminary results, predominantly from Type II fractures involving long bones, show that teicoplanin is effective in lowering the incidence of infection following open fractures.

Adolescent↗
PubMed1987

Complications of external fixation of open fractures of the tibia.

Forty-two cases of open fractures of the tibia treated by external fixation are presented. Forty-three per cent of patients developed sepsis around one or more pins. Pin track sepsis occurred in 78 per cent of cases involving transfixion pins through muscle and bone but in only 17 per cent of cases using transcutaneous half-pins. Malalignment of more than 5 degrees in any plane was seen in 38 per cent of cases, almost half of which increased in plaster after removal of the fixator.

Adolescent↗
PubMed1993

Complicated open fractures of the distal tibia treated by secondary interlocking nailing.

From January 1987 through December 1990, 28 consecutive distal tibial complicated open fractures in adults treated with primary external fixation and secondary closed Grosse-Kempf interlocking nails were prospectively studied and followed up for at least 1 year. All fractures were type IIIb open fractures and local soft-tissue coverage was performed at 3 to 5 days. The external fixation was maintained for an average of 22 days. The closed interlocking nails were inserted about 2 weeks after Hoffmann pins were removed. The results revealed a union rate of 85.7% (24 of 28) with a period to union of 5.8 +/- 1.4 months. Complications included 14.3% nonunion rate and a 7.2% deep infection rate, which were not difficult to treat. We conclude that secondary closed interlocking nailing is a simple and effective technique in treating distal tibial complicated open fractures.

Adult↗
PubMed1993

[Flap coverage of open fractures of the leg by high energy].

This retrospective study has been made on 23 patients with open fractures of the tibia, type III or IV in Byrd's classification. Ten of these patients showed an aggravation of the soft tissue lesions after the initial treatment. At the beginning of our study, 22 patients had already achieved union and 1 had been amputated. All the patients have had a covering by one or several flaps. The analysis of the results concerns different types of fracture: the time interval between the accident and the first covering by flap, the type of the flap, the length of the hospitalization, the complications; the recovery of the function. First covering by flap has been made in the acute phase in 6 cases, in the sub-acute phase in 12 cases and in the chronic phase in 5 cases. The results of the patients covered in the acute phase were better, than those of the patients covered by flap in the sub-acute or the chronic phase. Early covering of the open fractures of the tibia is recommended. A classification of the open fractures, derived from the classification of Byrd is suggested. We included a type "O" for the fractures with potential aggravation. Different types of flap of the leg have been described. Our behaviour in high energy fractures of the tibia is determined by the necessity to look for a potential fracture aggravation and by the intention of an early covering of the open fracture.

Adolescent↗
PubMed2000

Comparison of antibiotic beads and intravenous antibiotics in open fractures.

This study compared the efficacy of antibiotic impregnated beads with conventional intravenous antibiotics in the treatment of open fractures. A randomized prospective study was designed and conducted during a 29-month period. Sixty-seven patients with 75 open fractures were treated similarly, with the exception of the method of antibiotic administration, and were followed up for at least 1 year after injury. Infection occurred in two of 24 (8.3%) fractures treated with antibiotic beads alone and in two of 38 (5.3%) fractures treated with conventional intravenous antibiotics. In an unanticipated nonrandomized third cohort group, patients received antibiotic beads and intravenous antibiotics administered for nonorthopaedic reasons or limb threatening injury, or both. Two of 13 (15.4%) fractures in this high risk group became infected. Infection ultimately resolved in all fractures treated with antibiotic beads alone or antibiotic beads in conjunction with conventional intravenous antibiotics. This study was unable to achieve statistical significance; however, the data suggest antibiotic beads may be useful in preventing infection in open fractures. Thus, a larger multicenter randomized prospective study of isolated open fractures, eliminating other variables, is justified.

Administration, Topical↗
PubMedDate not supplied

The bacteriology of open fractures in Ile-Ife, Nigeria.

BACKGROUND: The objective of this study is to determine the pattern of bacterial isolates and antibiotic sensitivity profile in open fractures. Fifty-nine patients with open fractures of the lower limb long bones were studied. The majority of the cases were Gustilo and Anderson types II 21(35.6%), and IIIA 16(27.1%). METHOD: The patients were assessed by history taking, physical examination, and plain radiographs. Wound swabs were taken for bacteriological studies. Other necessary investigations were also done. During wound debridement open fractures were classified into Grades I, II and III using the Gustilo-Anderson method of classification. RESULTS: The infection rate was 45.8%. Gram-positive cocci and Gram-negative rods were isolated. On the whole Staphylococcus aureus 13(25%), and Coagulase-negative staphylococci (CONS) 14(26.9%), were the commonest organisms isolated. The commonest Gram-negative rods that were isolated from the wounds were Proteus mirabilis 9(17.3%), and Pseudomonas aeruginosa 8(15.4%). Multiple organisms were commonly isolated from the wounds. While all the organisms isolated showed very good sensitivity to gentamicin, cloxacillin and ofloxacin, most of the organisms were resistant to penicillin, ampicillin and tetracycline. The sensitivity ranged from 62.5% to 100%. Coagulase-negative Staphylococci (CONS) showed sensitivity to the widest range of antibiotics which included penicillin, ampicillin, chloramphenicol, gentamicin, cloxacillin and ofloxacin. The sensitivity ranged from 35.7% to 100%. There was statistically significant difference between the open tibial and femoral fracture cases with respect to the interval between injury and debridement time (p = 0.008); the rate of wound infection (p = 0.021); and the occurrence of osteomyelitis (p = 0.023). The commonest complications observed were wound infection 27(45.8%), and delayed fracture union 26(44.1%), which were commoner in the open tibial fractures. CONCLUSION: This study shows that Staphylococcus aureus and coagulase-negative staphylococci (CONS) were the commonest organisms associated with open fracture of the lower limbs in our centre and that delay in the initial wound debridement was a major predisposing factor to wound infection.

Adult↗
PubMed1986

[Study on experimental suppurative osteomyelitis--influence of an intramedullary nail on infection in open fractures].

Studies were conducted on temporary intramedullary fixation of open fractures containing pathogens to determine the degree of involvement of metal splints in the "establishment of infection" and whether or not there is a so-called "golden hour" for antibiotic administration. An open fracture was experimentally produced in the tibia of mice and inoculated with 10(2) or 10(3) cells of staphylococcus aureus. Two separate groups of intramedullary fixation and plaster cast fixation were compared. In the intramedullary fixation group, infection was established in 77.8% of the mice inoculated with 10(2) bacteria and in 100% of those inoculated with 10(3) cells, compared with 35.0% and 70.0% in the plaster cast fixation group. When antibiotic administration was started 12 hours after the inoculation, 4 of 5 mice of the intramedullary fixation group inoculated with 10(3) cells showed abundant bacterial cells after 2 weeks. Antibiotic administration started 6 hours after the inoculation achieved bacterial elimination in all mice.

Animals↗