[Experimental leukemia and statistics related to leukemia].
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The effectiveness of the combined therapy of leukemia P-388 with cyclophosphane and diazane was studied. The pattern of administering these substances was selected with due consideration of the cyclospecificity of their action. In a number of cases considerable synergism was observed, resulting in a cure of 100% of animals. Estimation of the effectiveness and the degree of synergism was made by the method of fractionation analysis, which allowed delineating some trends for providing the optimum combined therapy.
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