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At least 91 records · Page 5Linked to original sources

PubMed2000

The polymodal sensory cortex is crucial for controlling lateral postural stability: evidence from stroke patients.

In modern literature, internal models are considered as a general neural process for resolving sensory ambiguities, synthesising information from disparate sensory modalities, and combining efferent and afferent information. The polymodal sensory cortex, especially the temporoparietal junction (TPJ), is thought to be a nodal point of the network underlying these properties. According to this view, a pronounced disruption of the TPJ functioning should dramatically impair body balance. Surprisingly, little attention has been paid to this possible relationship, which was the subject of investigation in this study. Twenty-two brain-damaged patients and 14 healthy subjects were subjected to a self-regulated lateral balance task, performed while sitting for 8 s on a rocking platform. Their lateral body balance was analysed both with and without vision (darkness). Support displacements in the frontal plane were recorded by means of an accelerometer. Two criteria were taken into account to evaluate body stability in each trial: the number of aborted trials due to balance loss and the angular dispersion of the supporting surface. Lesions involving the temporoparietal junction were found to markedly increase body instability, both with and without vision. Therefore, the temporoparietal junction plays a pivotal role in lateral body stabilisation, irrespective of the sensory condition in which the task is performed. This suggests that body stability is controlled throughout internal model(s).

Adult↗

PubMed2002

[Divergent dislocation of the elbow in an adolescent. A case report].

A case of simultaneous proximal radio ulnar joint divergent dislocation combined with a bone avulsion of the coronoid apophysis of the same elbow in a 16 years-old girl is presented. After a closed reduction and two weeks of plaster immobilization, normal function of the elbow was recovered within three months. There are only ten cases reported of such a divergent elbow dislocation in modern literature.

Adolescent↗

PubMed2002

Do inflammatory cells participate in mammary gland involution?

The processes by which the involuting mammary gland clears residual milk and milk fat, as well as apoptotic cells, have gone largely unstudied in the modern literature. Here we review the evidence for and against the involvement of professional phagocytes of hematopoietic lineage in this process. Additionally we present evidence that mammary epithelial cells themselves are capable of phagocytosis and may be responsible for the majority of apoptotic cell and residual milk clearance during murine involution. In this scheme these cells regulate their cytokine production in response to apoptotic cells in a manner similar to other cells, including macrophages. The ensuing model describes a process of involution that actively suppresses an inflammatory response in the gland, allowing for effective tissue remodeling and damage prevention.

Animals↗

PubMed2000

Gangliocytic paraganglioma of the appendix.

AIMS: A case of gangliocytic paraganglioma is reported in the appendix which, to the best of our knowledge, is the first case at this particular site to be described in modern literature. METHODS AND RESULTS: A 47-year-old man with signs and symptoms of acute appendicitis underwent appendectomy. In the resected specimen a tumour with a diameter of 9 mm was found, which microscopically consisted of three different cell types: (a) epithelioid cells lying in a trabecular pattern and in formations reminiscent of 'Zellballen' as seen in paragangliomas (b) spindle cells and (c) ganglion-like cells. A diagnosis of 'gangliocytic paraganglioma' was made and confirmed by immunohistochemical and ultrastructural examination. CONCLUSION: Gangliocytic paragangliomas are rare tumours of uncertain histogenesis. More than 40 years ago a tumour in the appendix with features similar to our case was described by Masson as 'neuro-carcinoïde'. Concerning its origin, Masson, as well as other authors describing gangliocytic paragangliomas decades later, referred to the endodermal-neuroecto dermal complexes found by Van Campenhout. It is felt that the current finding of a gangliocytic paraganglioma in the appendix supports the hypothesis that gangliocytic paragangliomas arise from these embryonal structures.

Appendectomy↗

PubMed2002

Survey of current cementing techniques in total knee replacement.

BACKGROUND: Current techniques in total knee replacement (TKR) vary greatly. Cementing techniques in TKR are no exception. Identification of current trends would aid ongoing research into future developments. METHODS: A questionnaire was sent to all orthopaedic surgeons in Queensland, Australia. A range of factors influencing cementing techniques for the tibial plateau were investigated. RESULTS: Eighty-five percent of questionnaires were returned. Ninety-one percent of surgeons regularly cement the tibial plateau, 90% use some form of lavage prior to cement application, 95% of surgeons apply cement by hand only. Techniques aimed at increasing cement penetration (cement gun, intraosseous suction) are used infrequently. CONCLUSIONS: In contrast to total hip replacement, measures are not often taken to ensure that there is penetration of cement or a complete cement mantle into the tibial plateau in TKR. This may be because of a perceived lack of evidence in modern literature. This study also illustrates the wide variation in technique in a relatively common orthopaedic operation.

Arthroplasty, Replacement, Knee↗

PubMed2000

Posterior femoral cutaneous nerve mononeuropathy: a case report.

Isolated posterior femoral cutaneous nerve (PFCN) lesions are rare, with only six cases reported in the modern literature and one case documented with a nerve conduction study. A 25-year-old woman had sensory loss in the posterolateral thigh after two right gluteal intramuscular injections. Nerve conduction studies using Dumitru's technique showed a 9microV response on the asymptomatic side, but no response on the symptomatic side, and no abnormalities on needle examination of the back and lower extremities. Although a single case does not prove the validity of a technique, this case provides the rare opportunity to demonstrate the utility of Dumitru's technique.

Adult↗

PubMed2001

Pylephlebitis, portal-mesenteric thrombosis, and multiple liver abscesses owing to perforated appendicitis.

The authors report a case of a ruptured retrocecal appendix presenting with pylephlebitis, portal-mesenteric thrombosis, and multiple liver abscesses in an 8-year-old boy. A right hemicolectomy was performed, and liver abscesses were drained. The patient was treated with long-term antibiotics and anticoagulation. This the only case of perforated appendicitis associated with these 3 morbid complications in the modern literature.

Anti-Bacterial Agents↗

PubMedDate not supplied

[Epidemiological data on lower leg amputations. A study of 1487 amputations].

The examination is based on the operative amputee statistics at the university hospital Göttingen between 1983 and 1992 as well as the prosthetic treatment statistics at the university hospital for Technological Orthopedics and Rehabilitation (TO Münster) between January 1991 and March 1993. The comparison of epidemiologic data from both hospitals allow to give statements concerning etiology, level of amputation and age distribution. With a percentage of 78.6 dysvascular diseases were the principal cause for amputations at the Göttingen hospital, which is 10% less than described in modern literature. The respective percentage was 43% in Münster, followed by a 35.9% share for amputations caused by trauma. Our results demonstrate the relevance of amputations which are not due to dysvascular diseases in prosthetic treatment.

Adolescent↗

PubMedDate not supplied

[Eccentric ossification of the femur head epiphysis in hip dislocation; consequences for diagnosis and therapy].

Ossification of the upper femoral epiphysis is dependent on biomechanical laws. In babies with normal hips, the osseous nucleus develops in the centre of the epiphysis. In babies with hip dislocation, however, the altered biomechanical factors result in a different location of the nucleus. Ossification begins in a more lateral and cranial position. After reduction of the dislocated hip, either a second nucleus forms and grows together with the first nucleus, or the eccentric nucleus extends in a caudal direction. Both of these alternatives are physiological processes and should not be confused with necrosis of the epiphysis. The eccentric development of the nucleus is hardly mentioned in the modern literature, but it is of the greatest importance for diagnosis and therapy. Ignorance of the phenomenon of eccentric ossification may lead to a false assessment of the position of the femoral head. This mistaken impression may be heightened by an inappropriate X-ray technique: only by using techniques which take into account that the middle rotation position in children is different from that in adults can mistaken diagnoses and unnecessary operations be avoided. Examples are presented.

Cartilage, Articular↗

PubMed1976

Microvascular surgery. Techniques and applications in plastic surgery.

Methods of anastomosing small blood vessels are presented, together with an account of the authors' own experiences in the field of microvascular surgery. Practical suggestions are made to avoid pitfalls. The modern literature on experimental and clinical applications of microvascular technique in plastic and reconstructive surgery is reviewed. An extensive bibliography is offered as an aid to the interested reader.

Anticoagulants↗

PubMed1996

Early lens use: lenses found in context with their original objects.

The early history of optical lenses is poorly defined. Lens-like objects were used for jewelry or decorations for thousands of years, and technology necessary to make lenses was available. In antiquity, a number of activities would have benefited from image size enhancement, and a few lens-like objects have been found at sites where lens use was logical. Means for enhancing visibility of objects have been suggested. Two alternative positions are considered in modern literature: (1) Lenses existed and (2) Fine close work was executed by relatively young and/or nearsighted individuals. Neither argument meets necessary and sufficient conditions for proof of the existence of or lack of lens use. Both forms of image size enhancement might have co-existed, and added factors such as ambient illumination, contrast between the object examined and its background, and shadows must have affected visibility of items viewed. Most probably, optical properties of lens-like elements were appreciated often, across time, by artisans. What is not clear is to what extent general use of lenses resulted. Here, I draw attention to a number of individual lens-like artifacts and the objects intended to be viewed through them. All were decorative pieces or articles of jewelry. The existence of such artifacts has been reported previously. The unique feature in each case presented here is that the lens-like element and object to be viewed were permanently linked together, i.e., "frozen" in time and space. It can be inferred that at least the artisan appreciated the resulting optical effects. Clearly, too, the artist/artisan had to intend the object to be viewed through the lens. This analysis provides an additional useful approach to assessment of early lens use.

Eyeglasses↗

PubMed1984

Bacterial pseudomycosis (botryomycosis) in an otherwise normal child.

We report what we believe to be the first case in the modern literature of botryomycosis occurring in an otherwise normal 22-month-old child. The term bacterial pseudomycosis is more descriptive of the true nature of the condition and more meaningful to the clinician.

Dermatomycoses↗

PubMed1989

Toward optimizing the detection of atrial depolarization with floating bipolar electrodes.

Some concepts derived from modern literature on the physics of cardiac muscle conduction regarding optimization of the design of electrode systems for detection of atrial depolarization and a preliminary clinical corroboration of the concepts are presented. The concepts of most import are 1) that the mechanical dimensions of sensing electrodes in all planes have to be as small as possible relative to the dimensions of the extracellular waveform dimensions associated with depolarization action potentials, and 2) that the distance between bipolar electrodes should be tuned to be greater than the dimensions of the extracellular waveform to avoid subtractive interference patterns associated with saltatory propagation in aging cardiac muscle. Additionally, in the practical application of chronic atrial sensing from a single lead for use in an implanted VDD pacing system, it is also important to consider electrode size and its effect on impedance level.

Cardiac Pacing, Artificial↗

PubMed2006

A comparison of tobacco smoking among dentists in 15 countries.

This study was conducted as a systematic review of all modern literature describing the prevalence and associations of tobacco smoking among dentists. A keyword search of appropriate MeSH terms was initially undertaken to identify relevant material. Reference lists of manuscripts were also examined to locate further publications. A total of 35 English-language studies published in the past 25 years met the inclusion criteria. Results suggest that the prevalence of smoking is generally quite low among dentists, and that it has also declined in many countries during recent years. The lowest rates were documented in the United States (USA), Thailand, Finland, Australia and Canada. When multiple studies were examined over time, it appears that dentists in Australia and the USA consistently report the lowest prevalence. Overall, this review suggests that dentists have one of the lowest smoking rates among all health professionals. There were a few exceptions however, namely Italy and Jordan, where dentists appear to be smoking at fairly high rates. Nevertheless, it is important that tobacco usage continues its decline in future years so that the dental profession may remain exemplars at the forefront of preventive oral care.

Australia↗

PubMed1976

Bouyant density, conversion formulae, and the mole percent guanosine + cytosine content of Desulfovibrio sp.

A reevaluation of the original buoyant density conversion formula used to calculate the molar percentage guanosine + cytosine (% G + C) contents of the accepted species of genus Desulfovibrio has been undertaken. It would appear that the formula used gives values 4-5% lower than those obtained using formulae more generally cited in modern literature. Recalculations of % G + C content values for Lesulfovibrio DNA are presented using the formulae of three different workers, and are compared with those values originally used in the classification of genus Desulfovibrio.

Centrifugation, Density Gradient↗

PubMedDate not supplied

Some unresolved problems concerning the cochlear nerve.

Three types of afferent fibers innervate the hair cells of the organ of Corti: 1) specific radial fibers which establish contacts with a very few neighboring internal hair cells; 2) spiral fibers, each one of which establishes contact with a number of external hair cells distributed throughout long segments of the cochlea; and 3) unspecific radial fibers which are collaterals arising radially at irregular intervals from fibers of the ganglionic spiral bundles and which establish contact with internal hair cells. The existence of spiral ganglionic bundles of fibers oriented apicalward has long been described, and the fact that a number of ganglionic spiral fibers give off radial collaterals to innervate internal hair cells was illustrated by Cajal and by Lorente de Nó. However, those structural details are not mentioned in the modern literature. In the ventral nucleus there are neurons with efferent axons which join the trapezoid body and cells with short axons ramified within the ventral nucleus itself. Two types of cells with efferent axons are illustrated and described, the spherical or bushy cell and the basket cell; and it is shown that branches of division of the two types of efferent axons form association tracts which end in the tuberculum acusticum. Also, the fact is illustrated that fibers having their cells of origin in that tuberculum form association paths which end in the ventral nucleus by means of extensive ramifications which form numerous synaptic endings. The dendritic and fibrillar plexuses in the ventral nucleus are described, an analysis is made of the relationships between the two plexuses and of the synaptic junctions that mediate transmission of nerve impulses. The synaptic junctions belong to a considerable number of types and in all illustrations the important fact repeatedly appears that one and the same fiber may form synaptic endings of widely different sizes and shapes located either on the same neuron or, more frequently, on different neurons. The intimate structure of each type of synaptic ending cannot be revealed by light microscopy, but only light microscopy can reveal to which kind of fiber the synaptic endings do belong. The presentation is concluded with a brief and preliminary discussion of physiological corollaries of certain general features of the anatomy of the acoustic system.

Animals↗

PubMed1980

24-hour urine composition of Sri Lankan adults and their response to 100 mg dihydrochlorothiazide.

In the present study, 205 'normal hospitalised subjects' in the age group 16-60 years were included in a clinical trial to estimate the 24-hour urinary composition. Their response to 100 mg dihydrochlorothiazide was also determined. The study revealed that there is a marked difference in the 24-hour urine volume and composition between that observed in the present study and that presented in the modern literature; 100 mg dihydrochlorothiazide was found to produce a significant diuretic and natriuretic effect in normal Sri Lankan adults. There is a very high correlation between the volume of urine and the cations in the basal excretion as well as with the standard diuretic. The coefficient of regression of volume on cations in the basal excretion was found to be less than that with the standard diuretic.

Adolescent↗

PubMed2001

Normal embryonic stages of the longnose gar, Lepisosteus osseus.

BACKGROUND: Gaps exist in the modern literature that describes patterns of development in living groups of actinopterygian fishes. Relatively recent descriptions of development exist for the teleost fishes, bowfin, sturgeon, paddlefish and bichirs. Such literature dealing with the gars is to be found in older work, done approximately a century ago. The present study concerns the gars, of which the garpike, Lepisosteus osseus, is a representative example. RESULTS: The embryonic period of life of this fish is divided, as required for experimentation, into 34 stages, from fertilization to exhaustion of the yolk supply. Diagnostic structural characteristics are cited for each stage, and the rate of development is indicated. CONCLUSIONS: Three features of development are especially noted that compare or contrast with other members of the Neopterygii, and with the Chondrostei. These are meroblastic cleavage, a well-defined yolk syncytial layer (ysl), and a pit at the posterodorsal edge of the blastoderm, which defines an overhanging dorsal lip. Meroblastic cleavage and the ysl in the garpike show an affinity to those character states in the teleosts, though not with Amia, the other neopterygian fish. The posterodorsal pit and dorsal lip are reminiscent of similar features in the Chondrostei. Lepisosteus is unique among the Neopterygii with respect to this character state. Such comparisons set the stage for a broader understanding of the mechanisms for development in these organisms, and of the evolutionary relationships between them.

Animals↗