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Mutagenic effect of oxygen on barley seeds.

Resting barley seeds stored under oxygen at a pressure of 100 lb/in.(2) for 4 and 6 weeks exhibit a significant number of chromosome aberrations and mutations. The amount of cytogenetic damage increases with length of storage. The frequencies and types of changes are similar to those induced by 500 r to 1000 r of x-rays.

Chromosome Aberrations↗

Etiology of keratogenic metaplasia in the chorioallantoic membrane.

The effects of elevated O(2) and CO(2) concentrations on the occurrence of experimental keratogenic metaplasia in the chorion of the chick embryo were examined. Exposure to oxygen resulted in advanced keratinization of the chorion; carbon dioxide at elevated concentrations, in mixtures with air or oxygen, repressed the appearance of metaplastic changes, and the chorion retained its respiratory characteristics. The evidence reported here suggests that reduction of the CO(2) content in the gaseous environment of the chorion is causally contributory to the onset of the metaplastic events.

Animals↗