[Fertility and development in Brazil: an analysis with stepwise regression].
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Two abridged life tables for Koreans living in Japan for 1980 and 1985 are constructed using vital statistics and census data. Among the findings are that "the expectations of life at birth of Korean males in Japan are 68.4 in 1980 and 70.3 in 1985, whereas those values of Korean females in Japan are 78.3 in 1980 and 78.7 in 1985, respectively. Recent life expectancies of Koreans in Japan have come to resemble those of Japanese more than those of Koreans in Korea." (SUMMARY IN ENG)
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Birthweight data for 4474 live, healthy, singleton, full-term births of 2000g or over were analysed. The mean birthweights were 3136 +/- 445g at Goroka, and 3106 +/- 473g at Kainantu. Birthweights varied with sex, region of maternal origin, season and birth order, but not with year. Significant influences on Goroka birthweight values were, in order of importance, birth order, sex and season.
With the widespread introduction of the nitrogen-fixing legume sesbania, Sesbania sesban (L.) Merril, in agroforestry systems, the defoliating beetle Mesoplatys ochroptera Stål has become a serious pest of the trees in Africa. To determine within-field and within-plant spatial distribution of M. ochroptera on both seedlings and trees of sesbania, distribution statistics were computed using Iwao's mean crowding regression model. In 1- to 3-mo-old seedlings, the model accounted for 29.8, 32.2, and 61.0% of the variation observed in mean crowding to mean relationships in egg masses, larvae and adults, respectively. The model slopes of the regression were greater than unity for all stages indicating aggregated spatial distribution. Values of the intercept were greater than zero for egg masses, larvae and adults indicating that the basic components of the population are groups of individuals. The highest density (>80%) of mating and feeding adults was found in the upper third of 1- to 2-mo-old seedlings, while most of the egg masses were found in the lower half of seedlings. In trees, >60% of the individuals of all stages were found in the lower third of the foliage canopy, while <10% were found in the upper third. Sampling adults was found to be easier and gave better density estimates of M. ochroptera population than egg masses and larvae. Therefore, sampling plans useful for population studies and decision-making in pest management were developed for adults.
In recent years, it has been argued by some neuroanatomists that three-dimensional (3-D) counting approaches must be used in studies of neural systems, so that 'unbiased' counts of neurons can be obtained. By contrast, two-dimensional (2-D) cell-counting methods are said to be 'assumption-based' and to yield inaccurate results. Working from the premise that all scientific methodologies are assumption-based and suffer from inherent biases, the current review considers the relative strengths and weaknesses of 2-D versus 3-D counting approaches. This comparison is from the standpoint of predictive performance with respect to bias, variance and fidelity to the actual spatial arrangements of cells in the tissue under study. When these considerations are taken, together with the human resources that are required in using either methodology, 2-D methods offer more practical alternatives that might even provide more scientifically accurate estimates compared with their 3-D counterparts.
A continuous distribution approach, instead of the traditional mono- and multiexponential analysis, for determining quencher concentration in a heterogeneous system has been developed. A mathematical model of phosphorescence decay inside a volume with homogeneous concentration of phosphor and heterogeneous concentration of quencher was formulated to obtain pulse-response fitting functions for four different distributions of quencher concentration: rectangular, normal (Gaussian), gamma, and multimodal. The analysis was applied to parameter estimates of a heterogeneous distribution of oxygen tension (PO2) within a volume. Simulated phosphorescence decay data were randomly generated for different distributions and heterogeneity of PO2 inside the excitation/emission volume, consisting of 200 domains, and then fit with equations developed for the four models. Analysis using a monoexponential fit yielded a systematic error (underestimate) in mean PO2 that increased with the degree of heterogeneity. The fitting procedures based on the continuous distribution approach returned more accurate values for parameters of the generated PO2 distribution than did the monoexponential fit. The parameters of the fit (M = mean; sigma = standard deviation) were investigated as a function of signal-to-noise ratio (SNR = maximum signal amplitude/peak-to-peak noise). The best-fit parameter values were stable when SNR > or = 20. All four fitting models returned accurate values of M and sigma for different PO2 distributions. The ability of our procedures to resolve two different heterogeneous compartments was also demonstrated using a bimodal fitting model. An approximate scheme was formulated to allow calculation of the first moments of a spatial distribution of quencher without specifying the distribution. In addition, a procedure for the recovery of a histogram, representing the quencher concentration distribution, was developed and successfully tested.
The epidemiology of Strongyloides stercoralis was studied in families of clinical (reference) cases and their neighbours at endemic foci in Jamaica. Thirteen foci were studied based on the place of residence of a reference case. For each household of a reference case, the 4 most proximal neighbourhood households (spatial controls) were included in the study. Out of 312 persons contacted 244 were followed up using questionnaires, stool examination and serology. Prevalence of infection based on stool examination was 3.5% and on ELISA 24.2%. Prevalence increased with age but was not related to gender. Reference cases were significantly older than the general study population. The prevalence of infection based on both serology and stool examination was significantly higher in reference than in neighbouring households (the reference cases, themselves, were not included in the analysis). Furthermore, prevalence of infection was highest among persons who shared a bedroom with a reference case and decreased significantly with increasing spatial separation. This is indicative of close contact transmission which has not been previously shown for a geohelminth, but which is common among microparasites.
Reports of a suspected cluster of childhood leukaemia cases in West Central Phoenix have led to a number of epidemiological studies in the geographical area. We report here on a death certificate-based mortality study, which indicated an elevated rate ratio of 1.95 during 1966-1986, using the remainder of the Phoenix standard metropolitan statistical area (SMSA) as a comparison region. In the process of analysing the data from this study, a methodology for dealing with denominator variability in a standardized mortality ratio was developed using a simple linear Poisson model. This new approach is seen as being of general use in the analysis of standardized rate ratios (SRR), as well as being particularly appropriate for cluster investigations.