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Sutureless patch technique for postinfarction left ventricular rupture.

BACKGROUND: Left ventricular free wall rupture is an uncommon but catastrophic event after myocardial infarction and is associated with a high mortality. After prompt diagnosis some patients may be salvaged with immediate surgical intervention. Surgical techniques used to seal the rupture vary, as few surgeons have experience with this pathologic process. We report our experience using a sutureless patch technique to treat this entity. METHODS: A review of 6 consecutive patients during an 8-year period who were referred to one cardiac unit with postinfarction left ventricular rupture was conducted. RESULTS: There were 3 men and 3 women with an average age of 71.8 years. All were hemodynamically unstable, and 4 were in electromechanical dissociation. Echocardiography confirmed the diagnosis in 5 patients, and cardiac catheterization had been performed in 4 before rupture. All patients were treated promptly with fluid, inotropic agents, and, if needed, cardiopulmonary resuscitation and pericardiocentesis. Resuscitation was continued in the operating room, and the myocardial tear was sealed with a generous patch of unsupported felt secured to the heart with cyanoacrylate glue. Coronary artery bypass grafting was performed in 3 patients if the anatomy was known. All patients survived to the intensive care unit. One death occurred as a result of severe neurologic injury. Five patients were discharged from the hospital, and all were alive 2 months to 7.5 years after operation. CONCLUSIONS: A sutureless patch technique for the treatment of postinfarction rupture is simple, effective, and associated with a favorable outcome.

Aged↗

Comparison of the sutureless and suture-type epicardial electrodes in pediatric cardiac pacing.

Fourteen consecutive patients with the suture-type electrode (Group 1) were compared with the previous 14 patents having the sutureless electrode (Group 2). five patients in Group 1 had had failure with the sutureless electrode, for a total of 23 patients. In Group 1, no exit block was encountered. One patient had sensing problems corrected simply by increasing the pacer rate. One patient had generator failure and another, lead fracture. In 5 patients in Group 2, exit block developed early (less than 6 months after implantation); 3 patients had the problem twice, making a total of eight early failures. Two patients had late exit block (more than 6 months after implantation). Improved results with the suture-type electrode can probably be explained by its smaller head, larger surface area, ease of placement in a small space, and control of direction and depth of implantation.

Adolescent↗

Skin flap closure by dermal laser soldering: a wound healing model for sutureless hypospadias repair.

OBJECTIVES: Laser tissue soldering (LTS) with the diode laser and human albumin-hyaluronate-indocyanine green solder is a safe and effective method of providing an immediate leak-free closure during hypospadias repair. In this report, we compare the physiology, histology, and immunohistochemistry of wound healing following LTS and suturing in a rat skin flap model. METHODS: A 4 x 5-cm skin flap was raised and bisected (4 cm) on the dorsum of 48 Sprague-Dawley rats. The central wound was either closed from a dermal approach by suturing or LTS or left open, and studied at 0, 3, 5, 7, 10, 14, and 21 days postoperatively. An intraoperative comparison was made between suturing and LTS with respect to operative time. Postoperatively, flaps were excised for tensiometric analysis, and sections were stained with hematoxylin-eosin to define wound architecture. Resting skin temperature, laser exposed temperature without solder, and maximum temperature with solder (one drop) were measured at the level of the deep dermis, superficial striated muscle layer, and within the solder. Mean peak temperatures were recorded during a 1-minute laser activation time. RESULTS: Mean continuous suturing time (4.9 +/- 1.1 minutes) was significantly (P < 0.001) faster than either LTS (7.7 +/- 0.77 minutes) or discontinuous suturing (8.2 +/- 0.62 minutes). Two seromas (sutured) and two instances of partial wound dehiscence (1 sutured, 1 LTS) were noted. Tensile strength was increased significantly (P < 0.001) for up to 5 days in the LTS group, but was equal to suturing at 7 and 10 days. Immediate tensile strength after LTS was equivalent to a 7-day healed wound. At 14 days, wounds initially left open and those closed by LTS were stronger than sutured wounds (P < 0.05). There was no evidence of thermal injury or foreign body reaction in the LTS group. Solder was incorporated within the dermis in all wounds at 21 days. Laser activation of solder resulted in significant increases in temperature at all three tissue levels: 65.0 +/- 5.2 and 69.9 +/- 6.8 degrees C in the deep and superficial skin (no significant difference between the two), and 101 +/- 15.6 degrees C within the solder (P < 0.001 versus superficial and deep skin). CONCLUSIONS: Our results indicate that sutureless dermal LTS of skin flaps provides increased tensile strength for up to 7 days, with relatively greater tensile strength provided within the first 3 days. Our laser technique does not appear to alter the normal wound healing process. Rather, solder-tissue interaction initially, and extracellular matrix infiltration of solder later, provide the basis for improved wound strength. For hypospadias repair using skin flaps, these wound attributes may permit sutureless surgery.

Animals↗

The correlation between incision size and corneal shape changes in sutureless cataract surgery.

PURPOSE: To examine the correlation between incision size and corneal shape changes in sutureless surgery using corneal topography. METHODS: Two hundred eyes undergoing sutureless cataract surgery were assigned randomly to three groups according to the incision size: group A, 3.2-mm incision; group B, 4.0-mm incision; and group C, 5.0-mm incision. All eyes were examined by corneal topography preoperatively as well as at 1 week and at 1, 3, and 6 months after surgery. RESULTS: In the average of difference maps of eyes in the 3.2-mm incision group, a wound-related flattening in the peripheral cornea occurred 1 week after surgery, but decreased rapidly thereafter. Subsequently, no significant changes were observed in the cornea after 1 month. In the 4.0-mm incision group, with a reduction of the wound-related peripheral flattening, an irregular steepening appeared in the lower central cornea 6 months after surgery. In the 5.0-mm incision group, a similar steepening in the lower cornea occurred just after surgery. This steepening persisted and even extended to the upper central cornea in its later postoperative periods. CONCLUSION: The 3.2-mm incision hardly produced any irreversible corneal shape changes, whereas both the 4.0- and 5.0-mm incisions caused a persistent irregular steepening in the central cornea.

Adult↗

Video-assisted replacement or bypass grafting of the descending thoracic aorta with a new sutureless vascular prosthesis: an experimental study.

PURPOSE: The feasibility of the video-assisted insertion of a new sutureless vascular prosthesis was studied. METHODS: Seven sheep, weighing 25 to 35 kg, were operated on under general anesthesia. The animals were intubated with a single-lumen endotracheal tube and placed in the right lateral decubitus position. A thoracoscope was introduced in the 11th intercostal space, and a minithoracotomy (4 to 5 cm) was performed in the seventh intercostal space. After retraction of the lung, a short segment (10 cm) of the descending thoracic aorta was exposed. Our prosthesis was made of Dacron and was specifically designed to be inserted without a suture. After systemic heparinization, the aorta was cross-clamped with two vascular clamps introduced into the thoracic cavity through two 5-mm thoracic incisions. The aorta was either replaced (five cases) or bypass grafted (two cases). At the completion of the procedure, blood pressure was pharmacologically increased (5 mg intravenous bolus of epinephrine), and each anastomosis was checked for bleeding. All animals were killed, and the prosthesis was retrieved for macroscopic examination. RESULTS: The procedure was completed in each case without extension of the minithoracotomy. Insertion of the prosthesis was easy and fast, and completion of each anastomosis required 10 to 15 minutes. A 3- to 4-mm space between each clip was sufficient for proper attachment. All procedures were performed in less than 120 minutes. No bleeding was observed at the level of each anastomosis, even when a sustained high blood pressure was induced. The proper insertion of the prosthesis and the absence of any anastomotic stenosis was confirmed by means of macroscopic examination. CONCLUSION: Video-thoracoscopic replacement or bypass grafting of the descending thoracic aorta was easy with this new sutureless vascular prosthesis. Minimally invasive vascular surgery might be facilitated with such a prosthesis. However, long-term animal studies are required before human implantation can be undertaken.

Animals↗

Intra-articular migration of a sutureless arthroscopic rotator cuff fixation device.

Rotator cuff tears are a common orthopaedic condition. Recent new advances in arthroscopic equipment and devices has allowed many rotator cuff tears to be repaired arthroscopically. Some of these newer devices allow sutureless repair of rotator cuff tears. We report a case of failure in intra-articular migration of such a fixation device. Displacement of the device was noted 4 months after surgery on magnetic resonance arthography. The device was removed arthroscopically with no long-term sequelae. Nevertheless, it is important to recognize that these devices have the potential for intra-articular migration. Due diligence is required in placing these devices. As with all arthroscopic procedures, there appears to be a learning curve associated with the use of sutureless rotator cuff repair fixation devices.

Aged↗

Preliminary report of sutureless phacotrabeculectomy through a modified self-sealing scleral tunnel incision.

A method of combined cataract extraction and trabeculectomy using phacoemulsification through a modified 5 mm sutureless scleral tunnel incision is described. In eight patients who were followed for a minimum of five months in an initial series, the intraocular pressure (IOP) decreased to less than 19 mm Hg; six achieved this result at six months on no medication. The IOP decreased from a mean of 30.88 mm Hg preoperatively to 13.75 mm Hg at two months and 14.00 mm Hg at six months. The preoperative mean of 3.63 antiglaucoma medications per patient decreased to 0.25 postoperatively. Although all patients had advanced glaucomatous optic neuropathy with a preoperative mean cup/disc ratio of 0.79, visual acuity improved in six patients; four patients had an acuity of 20/40 or better at both one week and two months. Surgically induced astigmatism averaged 0.57 diopter (D) at two months, with a mean astigmatic shift of 0.08 D with the rule at two months and 0.41 D with the rule at three months. No hypotonous or flat anterior chambers were encountered; there were visible blebs in seven patients at six months. The sutureless phacotrabeculectomy preserves all the advantages of small incision phacoemulsification and appears to be a safe and effective combined procedure for IOP control in glaucoma patients with cataracts.

Aged↗

Sutureless cataract surgery with radial transverse incision.

I have developed a 3.5 mm radial transverse incision technique to perform sutureless cataract surgery using phacoemulsification and small incision lenses. The sutureless radial transverse incision was performed on 124 patients. The patient population excluded eyes with previous pathology, more than 2 diopters of corneal astigmatism, and requiring more than 22 diopter lens. Three month follow-up results using the Cravy method for determining astigmatism demonstrated less than 1.5 diopter of astigmatic change, astigmatic stabilization at one week, with no significant change in against-the-rule astigmatism at three months. Visual recovery demonstrated that 84% of patients achieved 20/40 or better at one month postoperatively.

Astigmatism↗

Sutureless one-handed intercapsular phacoemulsification. The keyhole technique.

Advances in the phacoemulsification technique have made small incision cataract surgery with lens implantation and sutureless incision closure a reality. This paper describes a step-by-step technique of small incision construction (the key), capsulorhexis (the keyhole), hydrodissection, intercapsular phacoemulsification (the doorway), and small incision lens implantation without the need for suture closure. A review of 200 cases with follow-up at one year is described. Evaluation of a postmortem eye at eight weeks following this sutureless technique indicates that these incisions are self-sealing, do not leak, do not induce astigmatic change, and allow rapid visual recovery.

Aged↗

Astigmatism after phacoemulsification with adjusted and unadjusted sutured versus sutureless 5.2 mm superior scleral incisions.

PURPOSE: To evaluate changes in astigmatism in the first 6 months after 5.2 mm superior scleral incision phacoemulsification using three different closures. SETTING: Department of Ophthalmology, Vejle Hospital, Denmark. METHODS: This study comprised 75 consecutive patients who had 5.2 mm superior scleral incision phacoemulsification. Patients were randomly assigned to one of three groups based on type of incision closure: Group 1, one intraoperatively adjusted cross suture; Group 2, one unadjusted cross suture; Group 3, no suture. Inclusion criteria were preoperative astigmatism of 2.00 diopters (D) or less (range of median 0.74 to 0.81 D) and no eye disease except cataract. Postoperative astigmatism was evaluated by keratometric cylinder, induced astigmatism (Naeser), and induced cylinder (Jaffe) on the first day and after 1 week and 1, 3, and 6 months. Time before stability was estimated. RESULTS: All groups had the same level of postoperative keratometric cylinder with no significant change between 1 week and 6 months (range of median 0.81 to 1.06 D). The groups reached the same level of induced astigmatism (Naeser) 3 to 6 months after surgery (range of median -0.44 to -0.64 D). Group 3 (sutureless) reached that value after 1 week, and induced astigmatism was stable thereafter. Both sutured groups (Groups 1 and 2) had a highly significant change between the first week and third month (P < .01). There were no significant intergroup differences in induced cylinder (Jaffe), which stabilized after 1 week in Groups 1 and 2 and after 1 month in Group 3 (range of median 0.61 to 0.87 D). During the early postoperative period, variation was highest in Group 2. CONCLUSIONS: Keratometric cylinder, induced astigmatism, and induced cylinder 3 to 6 months postoperatively were similar among the three groups, but early stability was only seen in the sutureless group. If a suture is used, intraoperative adjustment seems to result in lower variations in the early postoperative period.

Aged↗

Corneal changes after cataract surgery with 5.0 mm sutured and 3.5 mm sutureless clear corneal incisions.

PURPOSE: To study corneal changes after endocapsular phacoemulsification cataract extraction and intraocular lens (IOL) implantation with a 3.5 mm clear corneal sutureless incision or a 5.0 mm clear corneal incision with an absorbable suture. SETTING: Northwest Kansas Eye Clinic, Hays, Kansas, USA. METHODS: In a prospective study, 200 eyes were randomly distributed into two groups. Group A comprised 100 eyes that had a silicone IOL inserted through a 3.5 mm sutureless clear corneal incision. Group B comprised 100 eyes that had a 5.0 mm poly(methyl methacrylate) (PMMA) IOL inserted through a 5.0 mm clear corneal incision; one half of the closures used a single radial suture (Group B1), and the other half, an X suture (Group B2). Preoperatively, corneal topography and corneal endothelial cell counts were performed. Six to 8 months postoperatively, they were repeated and evaluated. Differential topography was used to determine the difference between the preoperative and postoperative corneas. During the final postoperative visit, IOL centration was evaluated. RESULTS: All closures produced only minimal changes in the corneal topographic indices. The postoperative corneas closely resembled the preoperative corneas. Polar K values showed a slight astigmatic shift in all groups. Group B2 was the only one to exhibit a with-the-rule shift. The change in endothelial cell counts was minimal and comparable in all three groups. CONCLUSION: The small amount of change in the corneal indices, especially in surface regularity, indicates that all corneas were relatively comparable and stable 6 to 9 months postoperatively regardless of the type of incision and closure method.

Adult↗

Intraocular pressure change after sutureless phacoemulsification and foldable posterior chamber lens implantation.

PURPOSE: To investigate the effect on intraocular pressure (IOP) of sutureless scleral and corneal tunnel Kelman phacoemulsification (KPE) with foldable posterior chamber intraocular lens (IOL) implantation. SETTING: Jules Stein Eye Institute, Los Angeles, California, USA. METHODS: Preoperative and postoperative (1 and 6 weeks and 6 to 8 months) IOP measurements of 385 consecutive eyes having uneventful phacoemulsification and foldable posterior chamber IOL implantation were reviewed retrospectively. A subset of 193 eyes for which no IOP measurements were missing at any follow-up were analyzed separately. RESULTS: Mean preoperative IOP was 15.8 mm Hg +/- 0.2 (+/- SE). It dropped postoperatively by 1.3 +/- 0.2 mm Hg at 1 week (P < .001), 2.5 +/- 0.2 mm Hg at 6 weeks (P < .001), and 2.2 +/- 0.2 mm Hg at 6 to 8 months (P < .001). Mean preoperative IOP for the subset without missing data was 16.0 +/- 0.3 mm Hg. It decreased by 1.1 +/- 0.3 mm Hg at 1 week (P < .001), 2.3 +/- 0.2 mm Hg at 6 weeks (P < .001), and 2.2 +/- 0.2 mm Hg at 6 to 8 months (P < .001). Wound construction (scleral versus corneal tunnel), anesthesia type (topical versus posterior orbital injection), the eye operated on, and patient age and sex did not significantly influence the postoperative pressure change. Patients with a preoperative diagnosis of glaucoma had significantly higher 1 week postoperative IOPs; however, the differences were statistically insignificant at 6 weeks and 6 to 8 months. CONCLUSION: Sutureless KPE with foldable posterior chamber IOL implantation lowered IOP by 1.1 to 2.5 mm Hg for the 6 months immediately following surgery. Glaucoma patients had a statistically significant initial rise in IOP at 1 week.

Adult↗

Effect of superior and temporal clear corneal incisions on astigmatism after sutureless phacoemulsification.

PURPOSE: To evaluate the effect of superior and temporal clear corneal incisions on astigmatism after sutureless, small incision phacoemulsification. SETTING: World Eye Hospital, Istanbul, Turkey. METHODS: This prospective study evaluated 40 eyes of 20 patients with cataract having bilateral, sutureless, small incision phacoemulsification by the same surgeon. A superior clear corneal incision was used in all right eyes and a temporal clear corneal incision in all left eyes. Mean preoperative astigmatism was 0.63 diopter (D) +/- 0.21 (SD) and 0.65 +/- 0.20 D, respectively. Mean patient age was 66.45 years. Patients were examined preoperatively and 1 day, 1 week, and 1 and 3 months postoperatively. RESULTS: Three months postoperatively, mean astigmatism was 1.60 +/- 0.37 D in the superior incision group and 0.83 +/- 0.19 D in the temporal incision group. Induced astigmatism calculated by vector analysis was 1.44 +/- 0.31 D and 0.62 +/- 0.28 D, respectively. The temporal incision group had significantly lower astigmatism at all follow-ups (P = .000). CONCLUSION: Upper lid pressure on the superior corneal incisions led to fluctuating, against-the-rule astigmatism that was significantly higher than that induced by temporal incisions.

Aged↗

Extracapsular cataract extraction with a sutureless incision for dense cataracts.

PURPOSE: To evaluate the use of extracapsular cataract extraction (ECCE) via a sutureless incision for dense cataracts. SETTING: Nagata Eye Clinic, Nara, Japan. METHODS: This retrospective study comprised 51 eyes of 45 consecutive patients with dense cataracts who had ECCE with a sutureless incision between January 1996 and April 1998. A scleral incision from 6.0 to 8.5 mm was made at 12 o'clock or between 9 and 12 o'clock (oblique incision). Measures of outcome included postoperative visual acuity, surgically induced astigmatism (polar value method and vector analysis), complications, and changes in corneal endothelial cell density and morphology. RESULTS: Self-sealing was achieved in 45 eyes (88.2%), but additional sutures were required in 6 (11.8%). Intraoperative complications included posterior capsule rupture in 3 eyes (5.9%) and iris prolapse in 2 (3.9%). Corneal flattening against the preoperative steep meridian was observed in the 12 o'clock incision group (0.24 diopter [D] +/- 1.23 [SD]) and in the oblique incision group (0.17 +/- 0.89 D). By vector analysis, the surgically induced vector was 1.41 +/- 0.72 D in the 12 o'clock incision group and 1.02 +/- 0.66 D in the oblique incision group. After surgery, the mean cell loss was 8.2% +/- 12.5%. There were no significant differences, however, between other preoperative and postoperative morphometric indexes. CONCLUSION: This fast, safe, and inexpensive technique may be a viable treatment for dense cataracts with large, hard nuclei.

Aged↗

Expandable prosthesis for sutureless anastomosis in thoracic aorta prosthetic substitution.

OBJECTIVE: Most complications of descending aorta prosthetic substitution seem mainly to be related directly (ischemia to distal organs, i.e. liver, kidney, spinal cord) or indirectly (extracorporeal circulation or shunts and systemic heparinization complications) to the duration of blood flow interruption. the purpose of this study is to report the results of animal experimentation of a new device for sutureless prosthetic substitution of the descending thoracic aorta, with a very short cross-clamping phase. METHODS: The device consists of expandable loops of stainless steel wires, sewn to the proximal end of a Dacron prosthesis. The stainless steel wire loops can be expanded and tightened by activating a removable guide in such a way that the prosthesis varies its diameter, while maintaining a regular cylindrical shape. The device was prepared in two different configurations, one for long segments (expandable prosthesis end) and the other to be used for very short segments or as an anastomotic ring between prosthetic or vascular stumps (quick anastomotic ring). The expandable prosthesis end was tested in swine experiments by performing the prosthetic substitution of the first 10 cm of descending cross-clamped aorta, the prosthesis being fixed with the device both at the proximal and the distal ends (six experiments). All animals survived the procedure, that was accomplished with a very short cross-clamping time. The quick anastomotic ring was used to anastomose two prosthesis ends, at the middle of the prosthetic segment used for descending aorta substitution (two swine), to perform the distal anastomosis in the same model of descending aorta substitution (one swine) and simply to re-anastomose a subtotally transected descending aorta (one swine). RESULTS: The present experience proved the reliability of the device to carry out a sutureless, accurate, simple and quick anastomosis. Its advantage over an intraluminal ringed prosthesis is much easier insertion of the retracted wired end into the vascular stumps, thus allowing for a prosthetic diameter appropriate to the substituted vessel. CONCLUSIONS: The reduced cross-clamping feature of the device would suggest its use mainly in thoracic aorta prosthetic substitution for the prevention of ischemic damage to distal organs; it can also be used to advantage wherever an end-to-end vascular or prosthetic anastomosis is indicated, providing an accurate, stented anastomosis.

Anastomosis, Surgical↗

Transconjunctival sutureless vitrectomy: initial experience and surgical tips.

OBJECTIVES: We report the operative details and surgical outcomes of 39 consecutive transconjunctival sutureless vitrectomies using the TSV 25 system. METHODS: We retrospectively reviewed the medical records of 35 patients (39 eyes) who underwent surgery using TSV 25 at the Department of Ophthalmology, Waterford Regional Hospital between March 2003 and February 2005. Preoperative, intraoperative and postoperative details were recorded and analysed. We also performed a systematic review of our surgical technique. RESULTS: Mean (+/-SD; range) duration of surgery was 32.85 (17.54; 5-85) min. Methods of anaesthesia included retrobulbar anaesthesia (31; 79.5%) and general anaesthesia (8; 20.5%). The mean (+/-SD; range) length of stay was 1.53 (1.25; 0-4) days. Mean (+/-SD; range) visual acuities (logMAR) were -1.335 (1.15; 0.0 to -3.0) and -0.803 (1.03; 0.1 to -3.0) preoperatively and postoperatively, respectively. The mean (+/-SD) intraocular pressures were 14.69 (4.64) mmHg and 11.56 (9.03) mmHg preoperatively and at the first dressing, respectively. Intraoperative complications included blockage of the TSV cutter tip during attempted clearance of organized intragel haemorrhage, thus requiring conversion to conventional trans pars plana vitrectomy (1; 2.6%). No other intraoperative complication arose. Complications in the postoperative period included: reactivation of dormant chorioretinal toxoplasmosis (1; 2.6%); postoperative posterior segment haemorrhage (3; 7.7%); hyphaema (1; 2.6%); transient postoperative hypotony (10; 25.6%). CONCLUSIONS: With appropriate case selection, and with appreciation of this technique's limitations, transconjunctival sutureless vitrectomy is a safe procedure.

Aged↗

Sutureless laser-welded anastomosis of the femoral artery and vein in rats using CO2 and Nd:YAG lasers.

In a comparative study, it was demonstrated that sutureless, laser-welded, end-to-end anastomoses in the rat femoral artery and vein are feasible, using either CO2 or Nd:YAG laser. Conventional microsurgical suture anastomoses served as the controls. Patency rates in experimental animals and controls were equal (96 to 100 percent). No aneurysms were observed. For successful laser welding, the anastomosis must be completely tension-free. In arteries, this was accomplished only by interposition of a graft from the contralateral artery. The absence of any foreign-body reaction and the saving in operative time support the use of sutureless laser welding.

Anastomosis, Surgical↗

[Sutureless vascular end-to-side anastomosis: an in-vivo test of a percutaneous concept in the animal model].

PURPOSE: To test a percutaneous concept for creation of a sutureless terminolateral vascular anastomosis in vivo. MATERIAL AND METHOD: By creating sideholes into the middle portion of a stent and a stent graft, both implants could be arranged in a Y-shaped configuration. An arteriovenous shunt was created in 3 sheep between the left carotid artery and the left external jugular vein. A stent graft was partially inserted into the venous lumen. Axial venous patency was restored by placing a stent through the sidehole into the graft lumen from an upstream puncture site. Graft patency was maintained by placing the sidehole of the stent at the bridging point between stent graft and stent with no stent struts crossing. Arterial end-to-end anastomosis was performed by retrograde placement of a stent graft into the arterial lumen. Both anastomoses were connected by a silicone tube. RESULTS: In all cases, a venous end-to-side anastomosis was created that was blood-tight and safely secured into the vascular lumen. CONCLUSION: Y-shaped configuration of stent and stent grafts through sideholes allows creation of sutureless end-to-side anastomoses in vivo.

Anastomosis, Surgical↗