Clinical aspects of taste disorders.
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There exist only a few reports on loss of taste sensation caused by dissection of the internal carotid artery. We describe a patient with carotid dissection and ipsilateral ageusia in the anterior two thirds of the tongue, presumably from a lesion of the chorda tympani. Ageusia in carotid dissection is explained by the close anatomic relation of the internal carotid artery and the chorda tympani in the short petrous bone. However, since extension of the space-occupying, dissecting intramural hematoma into the carotid channel as in our patient occurs infrequently--a probable precondition for the chorda tympani lesion--loss of taste is accordingly very rare. Reduced perfusion of the vasa nervorum can be excluded as another cause, because the chorda tympani is supplied only from branches of the external carotid artery.
To clarify the influence of chronic and excessive alcohol consumption on gustatory function, we examined taste functions of 20 male alcoholics by total oral gustometry using salty, sweet, sour, bitter and glutamate solutions. As results, all patients showed markedly impaired taste in all kinds of solutions comparing with age and sex matched healthy persons, nevertheless none of them recognized their impaired taste. Serum zinc levels of all patients were within reference range, but the most of them were within lower part of reference level. Although average serum zinc level increased significantly after 5 weeks of admission, serum zinc level showed no significant correlation with taste function. From these findings, we concluded that alcoholics had impaired taste functions probably due to impaired peripheral nervous system.
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