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Distribution of taste thresholds for phenylthiocarbamide among different age groups in Turkey.

The relation between age and taste threshold in populations living both in Istanbul and Resadiye, a town located in eastern part of Turkey, was investigated. In Turkey the nontaster/taster ratio has been found lower than in the other countries of Europe and Asia (3 ,4 ,8 ,9). With aging the taste sensitivity of tasters does diminish. However, the differences in the taste threshold levels of nontasters, in different age groups, have been found as being statistically not significant.

Adolescent

Medical management of taste and smell disorders.

Chemosensory dysfunction is most often secondary to one of only a few causes: nasal/sinus disease, viral infection, toxic chemical exposure, head trauma, as well as medication-related and idiopathic conditions. Medication-related disorders are corrected by discontinuance of the causative medicine. Our experiences have also shown that only dysfunctions of smell caused by disorders of the nose and/or sinuses are amendable to therapy.

Adrenal Cortex Hormones

Neurologic evaluation of taste and smell disorders.

Specific neurologic causes of chemosensory deficits are uncommon. A careful history and neurologic examination and the use of appropriate neurodiagnostic studies will identify the underlying cause in many cases and allow for appropriate management. The neurologic evaluation of the patient with abnormalities of smell, taste, or both is reviewed with specific reference to the disorders of the central and peripheral nervous system that may be causative.

Humans

Office management of taste and smell disorders.

Chemosensory disorders have been receiving increasing clinical attention but remain a difficult diagnostic problem. With the development of several well-standardized testing methods, taste or smell loss can now be verified, and this has added to knowledge concerning the common causes of dysfunction. Diagnosis typically rests upon the history and physical examination, but, except in the case of obstructive nasal and sinus pathologic conditions, therapy usually remains elusive.

Ambulatory Care

Caffeine taste test for panic disorder: adenosine receptor supersensitivity.

The present study introduces a novel measure of adenosine receptor sensitivity that is based on the action of specific receptor blockers (e.g., caffeine) to potentiate the ability to detect threshold quinine concentrations. The test is used to compare gustatory adenosinergic responses to caffeine challenges in normal controls and patients with panic disorder or posttraumatic stress disorder (PTSD). Panic disorder patients had an exaggerated response to the caffeine challenge that was not found in controls or PTSD patients, although the latter had higher anxiety scores on psychometric tests. The results are related to a model in which A1-adenosine receptors up-regulate in an attempt to modulate hyperactive excitatory neuronal systems.

Adult

A study of gustatory and olfactory function in patients with craniofacial anomalies.

Olfactory and gustatory function can be reiably studied in patients with craniofacial anomalies over the age of 7 years. In our unoperated patients with orbital hypertelorism or craniofacial dysostosis, preoperative evaluation of the olfactory and gustatory functions showed normal values. The same techniques were employed to study any changes in these modalities following reconstructive craniofacial surgery, and the results are presented.

Child

Chemical senses.

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Humans

Olfactory, auditory, and gustatory function in patients with bonadal dysgenesis.

The olfactory, auditory, and gustatory functions of 20 women with gonadal dysgenesis were studied. Various abnormalities of these functions were found, and they occurred principally in patients with mosaicism of the sex chromosomes. This is further evidence of the increased likelihood of various somatic abnormalities among women with gonadal dysgenesis, and particularly among those who carry more than one line of sex chromosomes.

Female

Burning mouth syndrome.

In spite of the normal clinical appearance of the oral mucosa, BMS subjects do have demonstrated changes in sensory perception and salivary factors in addition to alterations in psychologic features. Although some of these changes may be suggestive of a peripheral or central dysfunction of small afferent nerve fibres, the extent of this alteration and its cause both remain unclear. The existence of changes other than psychologic, however, do weaken the proposition that BMS has a primarily psychogenic origin and suggests instead that future research should address the question of other organic changes in BMS.

Adult

[Standardized examination methods for smell and taste and their clinical value].

The diagnostic of disturbances of the chemical senses is from a clinical standpoint still insufficient, as the literature of the whole world shows. Ten years of experimental and clinical investigations as well as the collection and evaluation of the experiences at the University ENT-Clinic Halle/S., GDR--have helped to develop some new tests and tools like a big and a small smell-case, two electrogustometers, the documentation by means of olfacto- and gustograms and so on. Now in the whole GDR a special group of ENT-scientists, members of our ENT society, are working on standardisation. The experiences will be official in our country. After the representation of our diagnostic system from to-day, as we are using them in our clinic, we are giving clinical examples as the diagnosis of the cranial nerves, the control of the treatment and so on, which are showing the usefulness of such examinations in smell and taste.

Humans