PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Trichiasis”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 91 records · Page 5Linked to original sources
PubMed1977

Lash excision in trichiasis.

A simple technique for lash excision in the surgical management of trichiasis is described. Of 13 patients treated with this technique, 11 had complete relief of symptoms and 2 had significant improvement in symptoms with the remaining symptoms attributable to other manifestations of their underlying disease. There were no complications in any of the cases from the surgical procedure itself. This procedure is quickly and easily performed and has been found to be particularly useful in elderly and debilitated patients, and in those patients whose trichiasis is associated with conjunctival scarring.

Eyelashes↗
PubMed2004

Risk factors for recurrence of postoperative trichiasis: implications for trachoma blindness prevention.

BACKGROUND: Trachoma is the leading worldwide cause of preventable blindness. Surgery can alleviate trachomatous trichiasis (TT), the blinding sequelae of trachoma, but recurrence rates are high. OBJECTIVE: To investigate risk factors for TT recurrence. METHODS: We conducted a prospective case-control cohort study in Nepal that included patients with TT who were undergoing bilamellar tarsal-rotation surgery and control subjects who have scarring but no TT. Conjunctivae were graded for trachoma and swabbed to detect Chlamydia trachomatis by in-house and commercial (Roche Amplicor; Roche Diagnostics Corp, Indianapolis, Ind)-polymerase chain reaction. Univariate and multivariate analyses were performed for associations with chlamydiae and other risk factors. RESULTS: Postoperative TT recurrence rates were 11.1% (4 cases) at 6 months and 25.0% (11 cases) at 12 months while no controls developed TT. Significantly, 5 (45.5%) of 11 patients with TT recurrences at 12 months had chlamydial infection at baseline (odds ratio, 6.0; 95% confidence interval, 1.5-24.3; P =.01), 8 (72.7%) at 6 months (odds ratio, 28; 95% confidence interval, 4.3-181.0; P <.001), and 9 (81.8%) at 12 months (odds ratio, 48; 95% confidence interval, 7.5-302.6; P =.00). No controls were infected during this time. Active trachoma and the baseline number of eyelashes touching the globe were also risk factors for TT recurrence. MAIN OUTCOME MEASURES: The outcome variable was TT recurrence at 6 and 12 months. CONCLUSION: To our knowledge, this is the first study to demonstrate that chlamydial infection at the time of surgery and at follow-up is a significant risk factor for postoperative TT recurrence.

Adult↗
PubMed1989

Cryotherapy for trichiasis in trachoma.

Trichiasis secondary to trachoma was treated in 137 eyelids from 64 patients in Saudi Arabia. Cryotherapy with high-flow nitrous oxide was applied to the lid margin for 45 seconds in a freeze-thaw-freeze cycle. The success rate of treated eyelids was 56% after one treatment and increased to 90% after a second treatment. Hypopigmentation of the highly pigmented eyelids of the Saudi population was our most significant complication (8% of treated lids). Because cryotherapy is portable and cost-effective and can be administered by paramedical personnel, it is ideal for use in regions where trachoma is endemic.

Adolescent↗
PubMed1992

Tarsotomy for the treatment of cicatricial entropion with trichiasis.

Transverse tarsotomy and lid margin rotation is a simple procedure that is effective in repositioning the entropic lid margin without requiring external incisions or grafting. We report the results of this procedure in 81 eyelids of 58 patients with cicatricial entropion and trichiasis who were followed up for a minimum of 6 months after surgery. Fifty-nine (94%) of sixty-three eyelids with mild to moderate cicatricial entropion were cured with this procedure. Patients with severe cicatricial entropion had a lower success rate with initial tarsotomy (55%), but in these patients the procedure had minimal complications and repeating the operation resulted in a higher success rate. Tarsotomy and lid margin rotation produces excellent cosmetic and functional results when used to treat patients with mild to moderate cicatricial entropion. In cases of more severe cicatricial entropion, we still recommend it as the initial procedure after which more complex modalities may be used if needed.

Adolescent↗
PubMed1976

Cryosurgery for treatment of trichiasis.

We cryosurgically destroyed eyelashes in rabbits and applied the technique to treat 23 selected patients with trichiasis. Liquid nitrogen was sprayed on the eyelid margin by using a double, rapid-freeze, slow-thaw cycle monitored by a subcutaneous thermocouple to -30 degrees C. It was an improvement on electrolysis and a simple alternative to surgery.

Animals↗
PubMed2005

Pattern of recurrence of trachomatous trichiasis after surgery surgical technique as an explanation.

OBJECTIVE: To evaluate the pattern of recurrence of trachomatous trichiasis (TT) after bilamellar tarsal rotation surgery for trachoma. DESIGN: Observational cohort. PARTICIPANTS: Three hundred eighty-four participants having at least 1 eye that had undergone a single TT surgery a minimum of 18 months before June 2001. The 630 study eyes were divided equally between left (311) and right (319) eyes. METHODS: Patients living in Central Tanzania were identified from surgical lists. Participants were screened for recurrence of TT, including evidence of epilation, after surgery. MAIN OUTCOME MEASURES: Detailed information on the location of recurrence was collected, including number of lashes touching the globe and location of trichiatic lashes (nasal, central, or temporal). RESULTS: One hundred seventy-six eyes had evidence of TT recurrence (28%), including 23 eyes having recently undergone epilation. In eyes without epilation, left eyes had a higher rate of recurrence than right eyes (32% vs. 25%; P = 0.05). Among eyes with recurrence originating from 1 location, recurrence was highest centrally (40%). Right eyes had nasal recurrence more often than temporal recurrence (33% vs. 20%). Left eyes had temporal recurrence more often than nasal recurrence (41% vs. 24%). CONCLUSIONS: Recurrence of TT after surgery is more common in the left eye and on the left side of the eyelid. The surgical procedure is more difficult to perform on the right side of the eyelid by a right-handed surgeon. This difficulty may lead to an unintentional change in surgical technique on the right, which may result in lower recurrence on that side.

Aged↗
PubMed1992

Argon laser treatment of trichiasis.

The argon laser was used to treat trichiasis in 44 patients over a five-year period. During follow-up intervals of between one month and more than four years (mean, 13 months), ablation of misdirected cilia was accomplished with one treatment in 26 patients (59%). No complications were observed. Laser is less effective than cryotherapy for destroying aberrant eyelashes, but cryotherapy is less precise and incites greater posttreatment inflammation. Argon laser treatment is a useful option when only a few, scattered eyelashes require ablation or in patients with disorders such as ocular pemphigoid, in which the stimulation of inflammation is undesirable.

Adult↗
PubMed1991

The treatment of recurrent trichiasis with argon laser photocoagulation.

We report our experience with the use of Argon laser photocoagulation for the treatment of recurrent trichiasis. A total of 28 lids (of 21 patients) with aberrant lashes were treated in our study. Each lash was treated with a beam of 50-200 micron (spot size), 0.2 s (time), and 1-1.2 Watt (power). Neither infiltration nor topical anaesthesia was used. The mean follow-up time was 6.57 months. Successful treatment with no evidence of recurrence was achieved in 67.9% of lids after one to two laser sessions. The remaining 32.1% of the lids required three to four sessions to achieve no recurrence of the condition. There was a significant correlation between the number of aberrant lashes per lid and the number of required laser sessions. Complete healing of the treated areas occurred within six weeks after treatment, with no vascularisation or distortion of the lid margin. Argon laser treatment appears to be a safe and effective alternative to the other recognised methods of therapy in selected cases.

Aged↗
PubMed1999

Trachoma: can trichiasis be treated with a sticking-plaster? A randomized clinical trial in China.

Trachoma is the most frequent cause of preventable blindness in the world. At the trichiasis/entropion stage, lid surgery is recommended, but many patients only use epilation, which does not prevent loss of vision. We developed a new treatment that should be more accessible than lid surgery and more effective than epilation: a sticking plaster that forces eyelashes back to their correct position. The first randomized controlled trial was conducted in Shanghai with 57 patients to compare the plaster method with epilation. After 3 months of follow-up, with no attrition, 67% of those treated by the new method presented a good clinical status, vs none of those treated by epilation (P < 0.001). The new treatment was well tolerated and lid function remained normal. Although our results show overwhelming benefit of this new, simple treatment for trachoma at the trichiasis stage, more research is needed at the primary health care level and in other settings to determine the potential use of the new method on a large scale and by nonspecialists.

Adult↗
PubMed2000

Should trichiasis surgery be offered in the village? A community randomised trial of village vs. health centre-based surgery.

INTRODUCTION: Surgery for trachomatous trichiasis prevents blindness and is advocated by the WHO as part of the SAFE strategy for the global elimination of trachoma. We conducted a randomised community trial to investigate the effect of providing surgery in villages on surgical uptake in The Gambia. METHODS: 56 villages from two divisions were assigned to eight pairs of clusters matched by geographical division and proximity. One cluster from each pair was randomly assigned to receive village-based surgery and the other cluster health centre-based surgery. Outcome measures were uptake rates and surgical results after 1 week and 3 months. The paired t-test was used to analyse the results. RESULTS: Overall uptake was 66% in the village-based clusters and 44% in the health centre-based clusters. Subjects in the village-based surgery arm had significantly shorter journey times (P = 0.01) and lower costs (P = 0.002). The mean difference in absolute acceptance rates of surgery was 20% better in village-based clusters (95% CI -9 to + 49%, P = 0.15), which would equate to an improvement of 45% (95% CI -20% to 120%) on the average acceptance rates of 44% in the health centre-based group. CONCLUSION: These results strongly suggest better surgical uptake when surgery is provided in patients' villages due to lower cost to the patient, time saved and less fear of the operation.

Blindness↗
PubMed1994

Argon laser treatment of trichiasis: a clinical and histopathologic evaluation.

Trichiasis is a common condition of multiple etiologies. Cryosurgery has been advocated as an effective means of treatment but may be associated with serious complications, including scar, skin depigmentation, and lid notching. We treated eight consecutive eyelids with the argon laser. At the end of a 3-month follow-up period, no recurrence was noted. The only observed complication was mild eyelid notching in one eyelid. Histopathologic evaluation of two specimens obtained 10 days and 5 weeks after laser treatment confirmed the highly localized coagulative effect of the laser with minimum destruction of adjacent tissues. Orientation of the eyelid so that the laser beam and the lash follicle are coaxial and careful measurement of the depth of vaporization of the lash follicle are important in confirming complete treatment and minimizing recurrence.

Adult↗
PubMed2000

Direct internal eyelash bulb extirpation for trichiasis.

PURPOSE: To evaluate the success of internal eyelash bulb extirpation in the management of trichiasis. METHODS: The procedure was performed on 26 consecutive eyelids. RESULTS: Our technique was successful in all cases, with no recurrence of signs or symptoms. CONCLUSIONS: Internal eyelash bulb extirpation is a safe and effective technique to remove trichiatic lashes, while avoiding injury to the conjunctiva.

Eyelashes↗
PubMed2004

Trichiasis associated with prostaglandin analog use.

A previously unreported complication of the use of prostaglandin analog medications for glaucoma therapy is described. A patient with monocular open-angle glaucoma had trichiasis, a condition associated with the use of a prostaglandin analog. The patient was treated with radiofrequency cautery and is now asymptomatic. The unmedicated eye remains asymptomatic to date. Increased lash length, thickness, and pigmentation are well-documented side effects of prostaglandin analog glaucoma drops. Physicians must consider this when prescribing these medications for patients with misdirected eyelashes.

Aged↗
PubMed1982

An operation for entropion and trichiasis. A composite of methods for lid margin rotation.

An operation for entropion/trichiasis is presented which is applicable to both upper and lower lids, and for grades of distortion from mild to severe. It is suitable for gross trachomatous lid disease in Aboriginal patients, and also for the discomfort of chronic cicatricial trichiasis in aged Caucasians. No new procedure is proposed. The method combines features of several well tried operations to free the inturned lid margin and resuture it in proper apposition.

Australia↗
PubMed1994

Congenital lower eyelid deformity with trichiasis (epiblepharon and entropion).

A series of 43 patients with congenital lower eyelid malposition and trichiasis (epiblepharon and entropion) is presented with clinical findings, family history, approach to management and results of treatment. The average age of patients was 9.3 years. A family history was present in 21%, and 30% had at least one parent of Oriental extraction. Thirty-nine patients underwent surgery for persistent symptoms due to chronic eyelash-globe contact. The surgical procedures performed were a modified Hotz procedure, Quickert sutures, and Jones-type retractor plication. Surgery was effective in at least 90% of all procedures.

Adolescent↗
PubMed2006

Impact of oral azithromycin on recurrence of trachomatous trichiasis in Nepal over 1 year.

BACKGROUND: Recently, a significant association between Chlamydia trachomatis infection and postoperative trachomatous trichiasis (TT) recurrence was shown. The current study evaluated whether azithromycin treatment at the time of surgery could reduce recurrence. METHODS: As part of Nepal's national trachoma control programme, patients received azithromycin (53 patients) or placebo (56 patients) at surgery. Conjunctivae were graded for trachoma and swabbed to detect chlamydiae preoperatively and postoperatively up to 12 months. Logistic regression was performed for associations of treatment option with recurrence, infection, and active trachoma (by eye and by patient). RESULTS: TT recurrence was 28.9% at 12 months. Recurrence was significantly lower for those with major TT at baseline in the azithromycin group at 12 months (p = 0.03); incident recurrence was also significantly lower at 6 months (OR, 0.056; 95% CI, 0 to 0.423; p = 0.004). There was a trend for increased recurrence among those with minor TT at baseline and for reduction of active trachoma and infection in the azithromycin group but not the placebo group. CONCLUSION: These data suggest that azithromycin treatment at the time of surgery may be warranted for patients with major TT. However, treatment should be investigated further for minor TT, for efficacy at subsequent time intervals and in other trachoma endemic settings.

Administration, Oral↗