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PubMed1993

Role of surgery and chemotherapy for peripheral lymph node tuberculosis.

A total of 105 patients with peripheral lymph node tuberculosis were treated by either surgical excision and chemotherapy or chemotherapy alone. The cervical nodes were affected in 98 patients, axillary nodes in four and inguinal nodes in three. Biopsy of the lymph nodes confirmed the diagnosis in all cases. Thirty-five patients who had sinus, ulcer or abscess underwent excision of the lymph nodes with drainage of the abscess, or resection of the sinus or ulcer. The remaining 70 patients received only chemotherapy. Chemotherapy in all patients consisted of isoniazid and ethambutol for 18 months. Of the 35 patients treated with surgery and chemotherapy, two had gaping wounds, one infection and one cellulitis of the face and neck. After 3 months, one patient had recurrence of the lymph node mass and one recurrence of a sinus; these were excised. Of the 70 patients treated only with chemotherapy, 13 were lost to follow-up. Four had non-healing wounds at the biopsy site, six wound infection and two sinus formation. Five of these patients had persistent lymph node masses, which were excised after 3 months. The remaining 52 patients had no recurrence.

Adolescent↗
PubMed1978

[Lymph node tuberculosis--today].

The peripheral tuberculosis of the lymph nodes on the neck, in the axilla and on the groin is described in its present epidemiological situation, its pathogenesis, diagnosis and therapy. Nowadays the tuberculosis of the lymph nodes most frequently occurs at older age and in women. In most cases the M. tuberculosis is the causative organism. The differential diagnosis must take into consideration many possibilities and sources of error--also for the following therapy and expert opinion--, in most cases it demands a histological and bacteriological examination of the exstirpated lymph nodes. This is at the same time the first step to therapy which consists in the removal of all enlarged lymph nodes in the area of the disease and in a 2-phase-chemotherapy for the duration of one year.

Adult↗