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At least 91 records · Page 5Linked to original sources
PubMed1979

Sarcoidosis of urethra simulating carcinoma.

Sarcoidosis of the urethra was found during endometrial curettage in a thirty-nine-year-old woman with a history of menometrorrhagia and decreased urine stream. Sarcoidosis is known to occur in many parts of the body, but an extensive search of the literature has failed to reveal any previous report of urethral involvement.

Adult↗
PubMed1979

Genitourinary leiomyomas.

Leiomyomas may originate from any anatomic location of smooth muscle in the genitourinary system but are uncommon neoplasms. Five unusual cases of leiomyomas arising from the renal pelvis, bladder, spermatic cord, and glans penis are presented. The leiomyoma arising from the glans penis in a three-year-old boy is the first case of a leiomyoma in that location noted in the literature. A review of leiomyomas from each genitourinary structure of origin is presented.

Child, Preschool↗
PubMed1985

Primary transitional cell carcinoma of prostatic periurethral ducts.

Primary transitional cell carcinoma of the prostatic periurethral ducts is a distinct histologic variety of prostate carcinoma. Traditional methods of therapy for adenocarcinoma of the prostate are ineffective. A review of the literature suggests that appropriate radical surgical therapy should be considered for early control of this disease.

Adenocarcinoma↗
PubMed1988

Treatment of urethral diseases with neodymium:YAG laser.

Over a thirty-month period, a wide variety of common urethral problems were treated on an ambulatory basis, with the neodymium:yttrium-aluminum garnet (Nd:YAG) laser. When used discriminately, laser treatment appears to be an effective modality for the management of selected urethral strictures. Thus far, excellent results have been obtained in 30 of 31 cases of short strictures where laser urethrotomy was performed as the first stricture procedure (average follow-up 10 months). Furthermore, in a series of 36 cases of secondary bladder neck contractures, all of the evaluated patients responded well (average follow-up 7 months). Good results were obtained in only 11 of 48 complicated strictures (average follow-up 14 months). However, while most of these extensive strictures were not eradicated, laser therapy generally produced a documented clinical improvement, comparable to urethrotomy or dilatation, in 15 of these cases. A series of 24 condylomata involving the urethra were treated satisfactorily, with no recurrences (average follow-up 13 months). Laser treatment also has been used successfully for the management of several urethral caruncles, urethral polyps, two meatal hemangiomas, one urethral carcinoma, and a distal duplicated urethra. Recently, the Nd:YAG laser has been applied to the prostatic urethra with vaporization of obstructing median bar hyperplasia. Favorable results have been achieved in 5 of 6 cases treated with a newly developed technique that utilizes direct laser contact. Retrograde ejaculation has not been encountered in these patients (average follow-up 6 months). All of these procedures have been accomplished in the office, largely without urethral catheterization. Lidocaine jelly occasionally supplemented with intravenous sedation provided satisfactory anesthesia.

Adult↗
PubMed1990

Vulvar Paget's disease: the need to exclude an invasive lesion.

Nineteen patients with intraepithelial Paget's disease of the vulva were treated surgically. Of these patients, five also had invasive Paget's disease of the vulva, two with only minimally invasive lesions. The latter two patients and one patient with a grossly invasive lesion progressed from intraepithelial Paget's disease. One patient had an associated carcinoma of the periurethral glands and an invasive Paget's lesion of the vagina. Since 5 of 19 patients (26%) had an associated noncontiguous carcinoma, the recommended initial workup included sigmoidoscopy, cystoscopy, mammogram, and colposcopy. Koilocytosis was found in 67% of patients. Exclusion of an invasive lesion from intra-epithelial Paget's disease was determined to be necessary because (1) the incidence of minimally invasive Paget's lesions may be significant; (2) intraepithelial Paget's disease has the capacity to become invasive; (3) the rate of associated invasive Paget's disease and/or underlying adnexal malignancies may exceed 20%; (4) grossly invasive lesions may be occult; and (5) the survival rate for grossly invasive lesions is low. Simple vulvectomy at a depth of at least 0.5 cm of subcutaneous tissue is recommended as optimal treatment for intraepithelial Paget's disease.

Aged↗
PubMed1984

A multiple-site perineal applicator (MUPIT) for treatment of prostatic, anorectal, and gynecologic malignancies.

Recently, transperineal interstitial-intracavitary applicators have been used to treat locally limited and advanced perineal and gynecologic malignancies. We have developed a single afterloading applicator, referred to as the "MUPIT" (Martinez Universal Perineal Interstitial Template), which with its prototypes has been utilized to treat 78 patients with malignancies of the cervix, vagina, female urethra, perineum, prostate, and anorectal region. The device basically consists of two acrylic cylinders, an acrylic template with a predrilled array of holes that serve as guides for trocars, and a cover plate. Some of the guide holes on the template are angled outward to permit a wide lateral coverage without danger of striking the ischium. The cylinders have an axial hole large enough to pass a central tandem or a suction tube for the drainage of secretions. Thus, the device allows for the interstitial placement of 192Ir ribbons as well as the intracavitary placement of either 137Cs tubes or 192Ir ribbons. In use, the cylinders are placed in the vagina and rectum and then fastened to the template, so that a fixed geometric relationship among the tumor volume, normal structures, and source placement is preserved throughout the course of the implantation. Hollow, closed-end, stainless steel trocars are then inserted through the guide holes that produce optimal coverage of the treatment volume. Appropriate computer programs also have been developed on a minicomputer for the corresponding dose-rate computations. These programs run with sufficient speed that they may be used for both the planning of the source placement beforehand and the computation of the actual dose-rate distribution obtained. The advantages of the system are (1) greater control of the placement of sources relative to the tumor volume and critical structures owing to the fixed geometry provided by the template and cylinders, and (2) improved dose-rate distributions obtained by means of computer-assisted optimization of the source placement and strength during the planning phase.

Anus Neoplasms↗
PubMed1985

Combination of external beam irradiation and multiple-site perineal applicator (MUPIT) for treatment of locally advanced or recurrent prostatic, anorectal, and gynecologic malignancies.

We have devised a single after-loading applicator, the Martinez Universal Perineal Interstitial Template (MUPIT), which has been used in combination with external beam irradiation to treat 104 patients with either locally advanced or recurrent malignancies of the cervix, vagina, female urethra, prostate, or anorectal region. Twenty-six patients treated for prostate cancer are excluded because of their short follow-up. Local failure developed in 13 of the 78 remaining patients (16.6%)--major complications developed in 4 patients (5.1%). Follow-up has been 1 year to 7 1/2 years; 60/78 patients have been followed for more than 2 years. All local recurrences and complications occurred before 18 months. The device consists of two acrylic cylinders, an acrylic template with an array of holes that serve as guides for trocars, and a cover plate. In use, the cylinders are placed in the vagina and/or rectum or both and then fastened to the template so that a fixed geometric relationship among the tumor volume, normal structures, and source placement is preserved throughout the course of the implantation. Appropriate computer programs have been developed to calculate the dose from these implants. The advantages of the system are (a) greater control of the placement of sources relative to the tumor volume and critical structures, as a result of the fixed geometry provided by the template and cylinders, and (b) improved dose-rate distributions obtained by means of computerized optimization of the source placement and strength during the planning phase. We conclude that the local control rate (83.4%) with low morbidity (5.1%) achieved with the combination of external beam irradiation and MUPIT applicator in these patients with locally advanced malignancies represents an improvement over previous published results with other applicators.

Adenocarcinoma↗
PubMed1987

Gastric and periurethral metastases from seminoma testis.

A case of seminoma testis with metastases to periurethral tissue and gastric submucosa is described. Response to treatment with irradiation and chemotherapy was good. Regression of the unusually sited tumour masses is demonstrated by barium meal and computed tomography. A brief review of gastric metastases is presented.

Adult↗
PubMed1988

Modified inguinal lymphadenectomy for carcinoma of the penis with preservation of saphenous veins: technique and preliminary results.

The controversy surrounding the management of patients with invasive carcinoma of the penis and clinically negative nodes is discussed. The rationale, technique and preliminary results of a modified inguinal lymphadenectomy in which the lateral and caudal extents of nodal excision are reduced, and the saphenous veins are preserved also are presented. This modified lymphadenectomy has been performed in 6 patients with invasive carcinoma of the penis or distal urethra without major or troublesome complications.

Carcinoma, Squamous Cell↗
PubMed1986

Treatment of urothelial carcinoma of the upper urinary tract following prostatocystectomy with mitomycin C instillation in the ileal loop.

We report a case of urothelial carcinoma of the upper urinary tract, which developed after prostatocystectomy. The patient was treated with instillations of 40 mg. mitomycin C in 40 ml. saline. No significant systemic side effects owing to perfusion of mitomycin C could be demonstrated. Complete remission of the small urothelial tumors occurred, as well as slight progression of a large pelvic carcinoma of the left kidney.

Aged↗
PubMed1986

A new, one-stage pedicled scrotal skin graft urethroplasty.

A new 1-stage procedure with a pedicled scrotal flap for bulbomembranous urethral reconstruction is described. The scrotal septum used as a pedicle provides good mobility to the flap. Because of this mobility the method appears to be applicable for reconstruction anywhere along the urethra.

Adenocarcinoma↗