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Implementation of the mini-CEX to evaluate medical students' clinical skills.

OBJECTIVE: The majority of medicine clerkships use faculty and resident summative ratings to assess medical students' clinical skills. Still, many medical students complete training without ever being observed performing a clinical skill. The mini-CEX is method of clinical skills assessment developed by the American Board of Internal Medicine for graduate medical education. The brief, focused encounters are feasible and produce scores with adequate reproducibility if enough observations are made.(1) The mini-CEX has been used in the medicine core clerkship, being performed once to augment feedback by faculty evaluators in the inpatient setting.(2) However, additional study is needed to address at least two feasibility issues if the mini-CEX is to be used as a measurement tool: (1) multiple settings (inpatient and outpatient) and (2) resident-completed evaluations. Our objective was to determine the feasibility of having students receive multiple mini-CEX's in both the inpatient and outpatient settings from resident and faculty evaluators. DESCRIPTION: We introduced the mini-CEX into our nine-week medicine clerkship (six weeks inpatient and three weeks outpatient) in July 2001. The clerkship uses four inpatient clinical sites and 16 outpatient practices. Inpatient faculty rotate on two-week blocks and residents on four-week blocks. At our clerkship orientation, each student (n = 39) received a booklet of ten adapted mini-CEX forms. In the mini-CEX, students are observed conducting a focused history and physical examination and then receive immediate feedback. Students are rated in seven competencies (interviewing, physical examination, professionalism, clinical judgment, counseling, organization, and overall clinical competence) using a nine-point rating scale (1 = unsatisfactory and 9 = superior). Our students were instructed to collect nine evaluations: three from faculty (one every two weeks), three from residents (one every two weeks), and three from their out-patient attendings (one per week). Students and evaluators were asked to rate their satisfaction with the exercise using a nine-point scale (1 = low and 9 = high). Students were asked to turn in their booklets the day of the exam. Prior to implementation, we reviewed the mini-CEX forms and rationale for use with residents and inpatient faculty. Similar information was mailed to outpatient faculty preceptors. DISCUSSION: Booklets were received from 32 students. The mean number of evaluations completed per student was 7.3 (range 2-9), for a total of 232 evaluations. Faculty completed 58% of the evaluations; 68% were from the inpatient setting. The observation and feedback took an average of 21 minutes and 8 minutes, respectively. Satisfaction with the exercise was rated by faculty/residents as 7.2 and by students as 6.8. We believe these findings support the feasibility of collecting multiple mini-CEX assessments from both inpatient and outpatient sites using faculty and resident evaluators. The feasibility of collecting multiple assessments is important if the mini-CEX is to be a reproducible assessment of clinical skills. Having established feasibility, we plan to look at the reproducibility and validity of mini-CEX scores in order to determine if it can be used as a formal means of clinical skills assessment. We also plan to evaluate the impact on the quality and specificity of end-of-clerkship summative ratings.

Clinical Competence↗

Augmented auditory feed back in the treatment of equinus gait in children.

This study is a report on the treatment of dynamic equinus in children with cerebral palsy or idiopathic toe-walking, by means of auditory augmented feedback. The initial results (after three months) showed improvement in every case, and in four patients with longer follow-up improvement appeared to be maintained or continued, although at a reduced pace. This treatment method is recommended only for children over the age of four years who are independently ambulatory, who have a range of ankle dorsiflexion to neutral or beyond with the knee extended, and who have a supportive and co-operative family.

Cerebral Palsy↗

Learning a new bimanual coordination pattern is influenced by existing attractors.

The present study investigates whether the acquisition of a rhythmical bimanual coordination pattern is influenced by existing intrinsic coordination tendencies. Participants were required to learn 1 of 5 new coordination patterns, whose relative phase phi was either 36, 60, or 90 degrees away from the 0 degree and 180 degree attractors, respectively. They performed 35 trials, each consisting of 2 conditions: In the augmented feedback condition, continuous visual guidance was provided, while in the normal feedback condition participants were required to rely on normal vision of their arms. We found that all to-be-learned patterns were performed with higher accuracy in the visually guided condition, whereas interference with pre-existing coordination tendencies was more pronounced in the normal vision condition. Comparing the learning progress of the 5 groups, we found for patterns close to anti-phase, a smaller improvement and significantly larger phase errors than for patterns close to in-phase. This indicates that the acquisition of a new phase relationship is influenced by existing attractors and that the 180 degree attractor interfered more strongly with the to-be-learned pattern than the 0 degree attractor.

Adult↗

Insulin stimulates the phosphorylation and activity of farnesyltransferase via the Ras-mitogen-activated protein kinase pathway.

Farnesylation of p21Ras by farnesyltransferase (FTase) is obligatory for anchoring p21Ras to the plasma membrane, where it can be activated by growth factors. Insulin significantly stimulates the phosphorylation of the alpha-subunit of FTase (4-fold) and the enzymatic activity of FTase in 3T3-L1 fibroblasts and adipocytes. FTase activity was assessed by the amount of [3H] mevalonate (a precursor of farnesyl) incorporated into p21Ras in vivo and by quantitating the amount of farnesylated p21Ras before and after insulin administration. Insulin-stimulated phosphorylation of the alpha-subunit of FTase in 3T3-L1 fibroblasts and adipocytes was blocked by the mitogen-activated protein/extracellular-signal regulated kinase-kinase inhibitor, PD98059, but not by wortmannin or bisindolylmaleimide. Additionally, PD98059 blocked insulin-stimulated [3H]mevalonic incorporation and farnesylation of unprocessed p21Ras in both cell lines. Furthermore, expression of the dominant negative mutant of p21Ras precluded insulin-stimulated phosphorylation of the FTase alpha-subunit and activation of its enzymatic activity. In contrast, 3T3-L1 fibroblasts, expressing the constitutively active Raf-1, exhibited enhanced phosphorylation of the FTase alpha-subunit. It seems that insulin's effect on the phosphorylation and activation of FTase in both fibroblasts and adipocytes is mediated via the Ras pathway, resulting in a positive feedback augmentation of the cellular pool of farnesylated p21Ras.

3T3 Cells↗

Virtual reality applications for motor rehabilitation after stroke.

Hemiparesis is the primary physical impairment underlying functional disability after stroke. A goal of rehabilitation is to enhance motor skill acquisition, which is a direct result of practice. However, frequency and duration of practice are limited in rehabilitation. Virtual reality (VR) is a computer technology that simulates real-life learning while providing augmented feedback and increased frequency, duration, and intensity of practiced tasks. The rate and extent of relearning of motor tasks could affect the duration, effectiveness, and cost of patient care. The purpose of this article is to review the use of VR training for motor rehabilitation after stroke.

Journal Article↗

Potentiating ballistic limb movements through voluntary production of the stretch-shorten cycle.

The purpose of this study was to examine the effect of learning to produce voluntarily a basic biomechanical mechanism, the stretch-shorten cycle (SSC), on the acceleration of a ballistic arm movement. The task required an elbow flexion at maximal effort performed with the forearm resting upon a horizontal manipulandum. Subjects in three groups received either no augmented feedback, feedback concerning the velocity of the flexion, or a combination of feedback on velocity and feedback related to the rate of stretch of the SSC during 80 training trials. The training trials were preceded by a pretest and followed by a posttest without feedback. Analyses showed that the subjects receiving feedback concerning the SSC exhibited earlier and greater peak angular acceleration than the other groups. These findings provide evidence that acquiring the control of relevant, basic mechanisms like the SSC may be useful in facilitating tasks requiring limb movements of maximal effort.

Biofeedback, Psychology↗

Suggestion as an aid to self-regulation of hand temperature.

Five subjects were instructed to alter the temperature of the dominant hand (two increase, three decrease) with the aid of an augmented feedback display. On baseline days and on alternate training days, subjects were presented with slide projections and heard a tape-recorded sentence during every other intertrial interval during a 15-minute discrete trial period. On baseline days, the imagery and suggestions were neutral in nature; on training days they suggested thermal conditions appropriate to the subject's task. Subjects displayed a significantly larger temperature change in the instructed direction on suggestion than on nonsuggestion training days.

Biofeedback, Psychology↗

Virtual environment system for motor tele-rehabilitation.

The present cutting-edge communication technology applied to the rehabilitation may change the real possibility of providing therapeutic treatments to the patients at their home. In order to confirm this assertion a current study on motor telerehabilitation was undertaken. Through a virtual reality based system, and a complementary video conference apparatus, we supplied five post stroke patients with a motor rehabilitation therapy. The rehabilitation technique was based on the augmented feedback. Subjects underwent the telerehabilitation program for six weeks. Before and after the evaluated therapy, arm motor performance and the activities of daily living were evaluated by the means of clinical scales and measuring the affected arm velocity (end-effector). This pilot study suggested that telerehabilitation could promote the learning of arm motor abilities at distance from the health facilities. From an economic point of view, it could be proposed also as an opportune strategy for saving resources.

Ambulatory Care↗

[Adaptive modification of neurophysiologic and vegetative processes during positive food and negative taste autoreinforcement].

A certain rhythm in brain activity of the cat was reinforced with milk in one series of feedback experiments, and with KCl solution--in another series. The 1st series feedback augmented the rhythm, particularly in the 12--15 Hz range, in the sensory--motor area. Obvious minimization of the rhyth m occurred in the 2nd series within the range of 4--7 Hz only, and negative reinforcement of the 12--15 Hz rhythm in these series induced neurosis. The vegetative activity estimated by the cardio--interval dynamics, was regarded as the correlate of emotional tension induced by biologically significant effect.

Adaptation, Physiological↗

Developmental orthopaedics. III: Toddlers.

The most common orthopaedic problems seen in toddlers are: (1) in-toeing due to femoral torsion, internal tibial torsion, talar torsion (persistent medial deviation of the neck of the talus), or metatarsus adductus; (2) genu valgus (bow-leg) and genu varus (knock-knee); and (3) pes valgus (flat-feet). In most cases these conditions will resolve spontaneously, as has been substantiated by a number of published studies. However, a small percentage of the disorders will persist if untreated. To prevent the deformity from becoming established and irreversible, treatment must begun while the patient is still young. Therefore the orthopaedist needs objective criteria to select those children in whom the deformity is likely to persist and who thus require prompt management. If femoral torsion persists, it becomes fixed by the time the child reaches eight years of age. Surgery is the only definitive treatment which can be offered, although gait training by augmented feedback methods may result in correcting by increasing the range of external rotation of the hip. Internal tibial torsion or talar torsion usually resolve spontaneously before the children reach seven years of age. However, in 8 per cent of cases in-toeing persists; it is cosmetically objectionable in the adult. I advise simple brace treatment in infants up to the age of 18 months if the medical deviation of the foot from the mid-sagittal plane is greater than 10 degrees. Because metatarsus adductus corrects spontaneously in many cases, some authors suggest that this condition should not be treated. However, I think it is prudent to use serial plaster-casts for infants under eight months of age in whom the deformity is moderate or severe. If treatment is withheld while the patient is observed, and if spontaneous correction does not occur, the deformity will become fixed and correctable only with surgery. Genu valgus and varus correct without treatment in the majority of patients. However, some cases of genu varus appear to develop into the progressive form of the disorder, Blount's disease. When the varus femoral-tibial angle exceeds the norm for age, early treatment with the Danish night-splint appears to prevent the development of this serious disease. 'Flat foot' (pes valgus) must be defined carefully by physical and radiographic examination. Treatment and radiographic examination. Treatment might be considered only for those feet classified as pes valgus with plantar flexed talus of 50 degrees or more. For children with this disorder between the ages of two and six years, a corrective moulded plastic shoe-insert may help to improve the abnormal anatomy while natural ligamentous tightening occurs.

Adolescent↗

The form of augmented force-feedback fields and the efficiency and satisfaction in computer-aided pointing tasks.

This study investigates operation efficiency and user satisfaction for spatial and temporal shapes of augmented force-feedback fields to be used with computer pointing devices in target acquisition tasks. In an experiment, three different force-field shapes at two different mean force levels were compared, with an electromechanical force-feedback trackball as control device and with efficiency and user satisfaction as dependent variables. Efficiency was measured by the time required to perform a certain task, and user satisfaction was measured through a subjective rating procedure. Satisfaction results indicate that to a rough approximation, participants can be grouped into those who prefer high and those who prefer low force levels. Members of the former group were most satisfied with force fields with a gradual start and an abrupt ending. This force-field shape also proved to be the most efficient for both groups. When all participants were considered as a single group, none of the effects was found to be statistically significant. A gender effect was also found; in both preference groups women achieved significantly shorter task completion times than men. Actual or potential applications of this research include enabling computer interaction for people prone to repetitive strain injuries and the increment of efficiency and satisfaction in human-computer interaction in general.

Adult↗

Big fish in small ponds: a social hierarchy analysis of intergroup bias.

High- and low-self-esteem group members received feedback about their individual performance as well as that of their own group and an out-group. They then evaluated both groups. Yoked-control observer individuals also provided group evaluations. In the in-group success/out-group failure condition, in-group enhancement tendencies were attenuated by individual failure feedback and augmented by individual success feedback. Low-self-esteem group members who received individual failure feedback showed favoritism toward the unsuccessful out-group over their own successful in-group. In the in-group failure/out-group success condition, in-group enhancement tendencies were attenuated by individual success feedback and augmented by individual failure feedback. Thus individuals' position in a social hierarchy mediates upward and downward social mobility strategies.

Achievement↗

Using mixed reality, force feedback and tactile augmentation to improve the realism of medical simulation.

This paper describes an application of a display approach which uses chromakey techniques to composite real and computer-generated images allowing a user to see his hands and medical instruments collocated with the display of virtual objects during a medical training simulation. Haptic feedback is provided through the use of a PHANTOM force feedback device in addition to tactile augmentation, which allows the user to touch virtual objects by introducing corresponding real objects in the workspace. A simplified catheter introducer insertion simulation was developed to demonstrate the capabilities of this approach.

Biomechanical Phenomena↗

Visual feedback alters the variations in corticospinal excitability that arise from rhythmic movements of the opposite limb.

Augmented visual feedback can have a profound bearing on the stability of bimanual coordination. Indeed, this has been used to render tractable the study of patterns of coordination that cannot otherwise be produced in a stable fashion. In previous investigations (Carson et al. 1999), we have shown that rhythmic movements, brought about by the contraction of muscles on one side of the body, lead to phase-locked changes in the excitability of homologous motor pathways of the opposite limb. The present study was conducted to assess whether these changes are influenced by the presence of visual feedback of the moving limb. Eight participants performed rhythmic flexion-extension movements of the left wrist to the beat of a metronome (1.5 Hz). In 50% of trials, visual feedback of wrist displacement was provided in relation to a target amplitude, defined by the mean movement amplitude generated during the immediately preceding no feedback trial. Motor potentials (MEPs) were evoked in the quiescent muscles of the right limb by magnetic stimulation of the left motor cortex. Consistent with our previous observations, MEP amplitudes were modulated during the movement cycle of the opposite limb. The extent of this modulation was, however, smaller in the presence of visual feedback of the moving limb (FCR omega2=0.41; ECR omega2=0.29) than in trials in which there was no visual feedback (FCR omega2=0.51; ECR omega2=0.48). In addition, the relationship between the level of FCR activation and the excitability of the homologous corticospinal pathway of the opposite limb was sensitive to the vision condition; the degree of correlation between the two variables was larger when there was no visual feedback of the moving limb. The results of the present study support the view that increases in the stability of bimanual coordination brought about by augmented feedback may be mediated by changes in the crossed modulation of excitability in homologous motor pathways.

Adult↗

Effects of manipulation of augmented knowledge of results and work surface angle on performance of a serial positioning task.

The effects of manipulating augmented information feedback on performance efficiency of 24 male adults in a simple motor skill were studied. The three levels of information feedback were no augmented knowledge of results, positive augmented knowledge of results and negative augmented knowledge of results, using light and tone as signal modes. The motor skill was a serial-positioning movement, simulating many industrial assembly tasks, and was given at three work surface angles (0 degrees, 9 degrees and 18 degrees), utilizing an automated geometric work station. Results indicated that, disregarding the signal mode, feedback had no effect on performance. However, when light was utilized as a mode of signal, results were superior at 0 degrees and 18 degrees angles when positive knowledge of results was provided. Work surface angle had little effect on performance efficiency, the 18 degrees angle being slightly superior to the 0 degrees and 9 degrees angles.

Adolescent↗

Sex, video-taped feedback and modeling effects on motor performance.

Two experiments were conducted to investigate the interaction of augmented information feedback and sex on accuracy and form of an overarm throwing pattern. In Exp. 1, a female model on video-tape was employed for instruction and recall of imposed form by 16 male and 16 female undergraduates. The original hypothesis that indeed there would be an interaction between the subjects' sex and type of augmented information feedback was not observed. In Exp. 2, essentially the same procedures were employed with another, similar group of subjects and several significant results were observed. The data suggest successive investigations to explore the possible effects of the model's sex on motor performance.

Adolescent↗

A comparative voltage and current-clamp analysis of feedback and feedforward synaptic transmission in the striatal microcircuit in vitro.

Striatal spiny projection (SP) neurons control movement initiation by integrating cortical inputs and inhibiting basal ganglia outputs. Central to this control lies a "microcircuit" that consists of a feedback pathway formed by axon collaterals between GABAergic SP neurons and a feedforward pathway from fast spiking (FS) GABAergic interneurons to SP neurons. Here, somatically evoked postsynaptic potentials (PSPs) and currents (PSCs) were compared for both pathways with dual whole cell patch recording in voltage- and current-clamp mode using cortex-striatum-substantia nigra organotypic cultures. On average, feedforward inputs were 1 ms earlier, more reliable, and about twice as large in amplitude compared with most feedback inputs. On the other hand, both pathways exhibited widely varying, partially overlapping amplitude distributions. This variability was already established for single FS neurons targeting many SP neurons. In response to precisely timed action potential bursts, feedforward and feedback inputs consistently showed short-term depression < or =50-70% in voltage-clamp, although feedback inputs also displayed strong augmentation in current-clamp in line with previous reports. The augmentation of feedback inputs was absent in gramicidin D perforated-patch recording, which also showed the natural reversal potential for both inputs to be near firing threshold. Preceding depolarizing feedback inputs during the down state did not consistently change subsequent postsynaptic action potentials. We conclude that feedback and feedforward inputs have their dominant effect during the up-state. The reversal potential close to the up-state potential, which supports shunting operation with millisecond precision and the strong synaptic depression, should enable both pathways to carry time-critical information.

Action Potentials↗

Reducing auditory feedback and the acquisition of motor response timing.

Three groups of subjects (n=10) attempted to move a lever 50 cm along a track in 1.50 sec under one of three auditory feedback conditions: Fully augmented increasing auditory feedback (FAF) in which a constant level of velocity-related auditory feedback was provided for all 25 learning trials, reducing auditory feedback (FAF) in which the level of feedback was progressively reduced over the learning trials, and no auditory feedback (NAF). All subjects performed 10 trials with no auditory feedback after a 10-min rest interval. The hypothesis that acquisition of the criterion task would be facilitated under RAF compared to FAF derived partial support. It was concluded that there is sufficient evidence to justify further investigation of reducing auditory feedback as a technique of motor skill acquisition.

Auditory Perception↗