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Monitoring source and domestic water quality in parallel with sanitary risk identification in northern Mozambique to prioritise protection interventions.

Microbiological water quality monitoring in Niassa province, Northern Mozambique, shows groundwater is not, in general, grossly contaminated though contamination levels are strongly linked to season and to risks observable at the wellhead, especially risks dealing with wellhead hygiene and maintenance. Diarrhea incidence, in general, is greatest in the rainy season suggesting poor wellhead protection as a potential mechanism for well contamination. Comparison of source water and stored water in the home shows that significant deterioration in source water quality can occur once transport and storage in the home is undertaken but that this deterioration is also related to the quality of the source water. This study shows that a structured approach to water quality monitoring, with targeted observations and an examination of the relationships between risk and water quality, is important to identify the priority interventions to be undertaken.

Diarrhea↗

Prioritising waiting lists.

The 'top 22' patient conditions on the general surgical waiting list at Guy's Hospital were rated independently by five general surgeons. Each surgeon estimated the peri-operative mortality rates associated with each treatment; the proportion of patients who failed to benefit; the effect of successful treatment on life expectancy and on the patients' quality of life. the mean values were used to estimate the expected net benefits (in terms of quality-adjusted life-years) from treatment one year earlier than might otherwise have been the case. These benefits were then related to the operating times and length of stay associated with each treatment; this identified which treatments offered the greatest benefit per unit of each constrained resource. Of all conditions examined anal fissures where shown to be the least resource intensive in relation to the benefits generated, whilst varicose veins and epigastric hernias proved otherwise. For the full potential of this approach to be realised it needs to be repeated in other places and in other specialties. It nevertheless offers a more rational basis for interpreting waiting list data than presently exists and by using the short-cut methods is a relatively cheap way of generating much useful data.

Data Collection↗

How do rural households perceive and prioritise malaria and mosquito nets? A study in five communities of Nigeria.

The aim of this study was to determine households' levels of prioritization and perception of malaria, ordinary mosquito nets and insecticide-treated nets (ITNs). A cross-sectional survey was conducted in five malaria holo-endemic communities in Enugu State, South-eastern Nigeria. The household heads or the representatives from randomly selected households were interviewed, using a pre-tested interviewer-administered questionnaire. The majority of the respondents had a good knowledge about malaria and the use of ordinary mosquito nets to prevent malaria. However, few knew about the existence of ITNs. Most respondents also stated that malaria was a priority problem and perceived some risk of contracting it. Despite the high level of knowledge about the use of mosquito nets, only 14.0%, 15.7%, 9.6% and 8.0% of the respondents from four of the communities had ever purchased any type of mosquito nets, except in Orba where the proportion was 50.3%. However, more than 80% in all the communities expressed a desire to buy insecticide-treated mosquito nets for the prevention of mosquito bites. There was considerable knowledge about malaria and the use of mosquito nets to prevent it. There were also high levels of prioritization of the disease, mosquito nets and ITNs which signalled the possibility of establishing sustainable community-based ITN programmes, especially as households wanted to buy the ITNs.

Adult↗

Analysis of scenarios for sewerage, wastewater treatment and prioritised load on environment from the Greater City of Copenhagen.

The sewer system for the Greater Copenhagen area covers an area of 4460 ha contributing to the runoff. The total area serves in total 8 municipalities, however it is dominated by the areas in the City of Copenhagen proper. The catchments merge into interceptors, which feed two large treatment plants. The effluent from the two treatment plants discharges during dry weather to Oresund, the sound between Denmark and Sweden. This large system has been analysed for selected scenarios with respect to handling runoff in an optimal way in order to minimise the loads on the most sensitive receiving waters and optimising treatment plant performance.

Cities↗

Prioritising access to antiretroviral therapy in resource-poor settings.

Until quite recently, bringing antiretroviral therapy to severely resource-constrained countries was not considered to be a priority. It was widely felt that in these settings a preventive HIV vaccine is the only way to win the war. Antiretroviral therapy was perceived to be too expensive and complex, to pose impossible monitoring demands, and to drain valuable resources from more important prevention efforts. However, both from a humanitarian and an economic and developmental perspective, we cannot afford not to bring highly active antiretroviral therapy (HAART) to these settings.

Acquired Immunodeficiency Syndrome↗

[The prioritisation of genetic screening with primary haemochromatosis as an example].

In 1994, the Health Council of the Netherlands published a report entitled 'Genetic screening' which contained 12 criteria for genetic screening programmes. However, the list does not prioritize the various criteria. From the list we have selected two criteria that we consider to be the most important. Firstly, the genetic screening test should be able to discriminate between subjects who are likely to develop the disease and those who are not. Secondly, there should be an effective treatment for subjects with the genetic defect. From this point of view, for example, screening for the C282Y mutation is not a suitable approach for detecting primary haemochromatosis. Although 85-90% of the patients with this disease are homozygous for this mutation, the majority of the carriers will not develop the disease. The 12 criteria of the Health Council of the Netherlands are still applicable. However, when taking a decision as to whether or not genetic screening is useful, we recommend that priority be given to the two primary criteria.

Diagnosis, Differential↗

Prioritising road safety initiatives: fatality versus social cost.

In an effort to reduce road trauma, traffic authorities in Australia and New Zealand have implemented a series of countermeasures aimed primarily at reducing road fatalities. Although the social cost associated with fatal crashes is significant, it nevertheless constitutes a relatively small portion of the total social cost of road crashes. Since the relative influences of the contributing factors to fatal crashes may not be the same as those for less severe crashes, an overemphasis on fatal crashes may not result in an optimal allocation of scarce road safety resources.

Accident Prevention↗