[Histopathological findings on the processes of idiopathic calcification and pseudocalcification of cerebral vessels].
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The correlations of dental mineralization stages, skeletal mineralization, body-height and weight were determined for each year between age 4 and 14 for 121 boys and 111 girls of the serial experimental group of the Burlington Growth Centre. Dental development related more strongly to morphological development than to skeletal development in both sexes, and skeletal age was more strongly related to morphological age than to dental stage. The relationship of individual teeth to skeletal age, height and weight were different but consistent in a sex-specific pattern. In males, both skeletal mineralization and dental mineralization, particularly of the first molars, were more closely related to height than to weight. In the females, skeletal and dental mineralization, especially of the second molars, were more closely related to weight from age 7 than to height. These relationships were significant in both pre-adolescent and adolescent years. In both these periods, skeletal age and body size related most strongly to late stages of tooth formation. Hence, from an early age, the stages of dental, skeletal and morphological maturation were significantly interrelated in a pattern that was specific for individual teeth and for sex.
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This paper develops the concept that the dramatic appearance of calcareous skeletons in the Lower Cambrian is directly related to the origin of refined mechanisms of intracellular modulation of calcium ion concentration. An homologous family of calcium modulated proteins has recently been discovered. These proteins contain "EF hands", involved in the maintenance of low concentrations of intracellular calcium and the informational use of calcium ion flow (Kretsinger, 1977). The evolution of this specialized calcium physiology, especially in muscle systems, coupled with natural selection by predators are identified as some of the preadaptations for the impressive Tommotian diversification of calcified metazoans. The distribution of calcium biominerals in the phyla of the five kingdoms and the time of first appearance of calcareous mineralization in the fossil record are tabulated. Macroscopic calcified hard parts apparently required the prior evolution of certain cell, tissue and organ system physiologies which are briefly discussed here.
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This study examined the effects of increasing milk on bone and body composition responses to resistance training in adolescents. Twenty-eight boys (13 to 17 years of age) were randomly assigned to consume, in addition to their habitual diet, 3 servings/day of 1% fluid milk (n=14) or juice not fortified with calcium (n=14) while engaged in a 12-week resistance-training program. For all subjects combined, there were significant (P<or=.05) changes in height (+0.5%), sigmaseven skin folds (-7.7%), body mass (+2.6%), lean body mass (+5.1%), fat mass (-9.3%), whole-body bone mineral content (+3.6%), bone mineral density (+1.8%), and maximal strength in the squat (+43%) and bench press (+23%). Compared with juice, the milk group had a significantly greater increase in bone mineral density (0.014 vs 0.028 g/cm(2)). Increasing intake of milk in physically active adolescent boys may enhance bone health.