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PubMed1981

Tympanoplasty.

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Ear Ossicles↗
PubMed1980

A survey of Canadian otolaryngologists on the management of middle ear effusions.

Members of the Canadian Otolaryngological Society were surveyed by way of a questionnaire regarding their treatment of the middle ear effusion. Sixty-seven per cent of the members polled replied. The majority of respondents utilized similar conservative measures, but for varied time periods, before proceeding to surgical management. Surgery generally involved insertion of a ventilating tube plus an additional procedure which was most frequently an adenoidectomy. Other aspects surveyed included the role of allergy, type of tube used, site of tube insertion, and the question of swimming with the tube in place. The survey indicated widespread agreement in both conservative and surgical management of this common problem.

Attitude of Health Personnel↗
PubMed1980

Recurrent cholesteatoma in combined approach tympanoplasty.

Forty-six ears--13 cholesteatoma ears and 33 non-cholesteatoma ears--with preoperative poor Eustachian tube function and a healed tympanic membrane more than 12 months after surgery were investigated. It was found that retractions occurred independent of previous cholesteatoma or surgical procedure. Also, retractions were associated with intratympanic negative air pressure, indicating dysfunction of the Eustachian tube.

Adult↗
PubMed1976

Tympanic reconstruction. Fifteen year report on tympanoplasty. Part II.

This survey was carried out to evaluate techniques in current use for the treatment of chronic suppurative otitis media. Part I concerns the incidence of cholesteatomatous complications following combined approach tympanoplasty (CAT). Residual and Recurrent cholesteatoma occurred much more frequently than had been expected or reported elsewhere. Although the incidence of Recurrent cholesteatoma has been markedly reduced by technical modifications, Residual cholesteatoma was discovered inadvertently in one out of every seven previously cholesteatomatous ears in which a second operation for ossicular reconstruction was performed. In at least one-third the disease had been left in the epitympanum. Although many cholesteatomatous cysts might lie dormant for years, and possibly never give rise to serious consequences, it can no longer be claimed that CAT provides a satisfactory means of eradicating cholesteatoma unless re-exploration operations were continued until eventually the tubotympanic cleft could be shown free of cholesteatoma.

Animals↗
PubMed1994

Repair of chronic tympanic membrane perforations using epidermal growth factor: progress toward clinical application.

In an earlier study, epidermal growth factor (EGF) was shown to be effective in healing chronic tympanic membrane (TM) perforations in the chinchilla. The original protocol required rimming of the perforation's epithelial edge, application of a paper patch, placement of a Gelfoam pledget, and then administration of EGF solution. To develop a simple outpatient method of healing chronic TM perforations, an attempt was made to simplify the treatment protocol while preserving efficacy. In the modified experimental protocol, a large Gelfoam pledget was placed over the chronic perforation in contact with the residual TM, without mechanical disruption of the perforation edge or use of a paper patch. Then EGF in phosphate buffered saline (PBS) was applied to the Gelfoam pledget (50 microL of 0.5 mg EGF/mL PBS). A series of control ears received Gelfoam pledgets and PBS. Complete closure of the TM perforation was achieved in 80 percent (12/15) of treated ears but in only 20 percent (3/15) of controls (p < 0.01), results similar to those obtained with the original protocol. At long-term follow-up, 4 to 9 months after treatment, EGF-healed TMs were histologically similar to normal TMs, both in their overall thickness and in the relative proportions of the three component layers. In contrast, the few spontaneously healed TMs from the control group were less than half the thickness of normal TMs. To ascertain the optimal EGF concentration for therapeutic effect, a dose ranging study was undertaken.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗