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[Description and integration of biomedical information resources by metadata].

With the development and utilization of computer techniques, Internet is playing an important role in information dissemination. There are abundant biomedical resources on the Internet. Accessing biomedical information is more dependent on the Internet than ever. It is important to explore new methods to describe and manage information resources. We have analyzed biomedical databases, search engines, web sites, and the metadata adopted by biomedical databases. The results show that biomedical information resources are characterized by electronic format, networking, dynamia, and dispersion. Describing a resource with metadata allows it to be understood by both humans and machines in ways that promote interoperability. Metadata interoperability has to be the underlying principle for networked information management. It directly impinges on information sharing, interchange, and accessibility across the boundaries of systems, languages, and geographic locations. We can use metadata to describe biomedical information and to integrate resources. It will benefit the people to access, select, and utilize biomedical information resources.

Computer Communication Networks↗

[Retrieval and use of acupuncture and moxibustion medical information in internet].

OBJECTIVE: To introduce a retrieval method for acupuncture and moxibustion medical information in internet so as to use them. METHODS: Retrieval and use of acupuncture and moxibustion medical information resources in the internet are illustrated from use of searching engines, the acupuncture webside and full-text literature databank. CONCLUSION: There are very abundant acupuncture and moxibustion medical information resources in internet, which should be used fully and effectively.

Acupuncture Therapy↗

Applying hybrid algorithms for text matching to automated biomedical vocabulary mapping.

Several biomedical vocabularies are often used by clinical applications due to their different domain(s) of coverage, intended use, etc. Mapping them to a reference terminology is essential for inter-systems interoperability. Manual vocabulary mapping is labor-intensive and allows room for inconsistencies. It requires manual searching for synonyms, abbreviation expansions, variations, etc., placing additional burden on the mappers. Furthermore, local vocabularies may use non-standard words and abbreviations, posing additional problems. However, much of this process can be automated to provide decision-support, allowing mappers to focus on steps that absolutely need their expertise. We developed hybrid algorithms comprising of rules, permutations, sequence alignment and cost algorithms that utilize the UMLS SPECIALIST Lexicon, a custom knowledgebase and a search engine to automatically find probable matches, allowing mappers to select the best match from this list. We discuss the techniques, results from assisting to map a local codeset, and scope for generalizability.

Algorithms↗

Patient location strategies for pediatric long-term follow-up studies.

BACKGROUND: Poor follow-up rates greatly diminish the validity of prospective and long-term studies. Therefore, locating patients is of critical importance. This is especially true in populations treated during childhood because addresses will change several times in intervening years. Recent publications have reported new strategies for patient location. The purpose of this study is to test an algorithm proposed by King et al., as well as other search methods, using a cohort of patients treated for clubfoot in childhood METHODS: The study population included 126 patients with clubfeet treated between 1950 and 1967. We followed the search algorithm proposed by King et al. In addition, we used state driver's license records, Reunitetonight.com, and Intelius.com. Patients were considered to be found when they returned a postage-paid reply letter or were contacted by phone. RESULTS: Using web pages recommended by King et al. we located 26 of 126 (21 percent) patients. Operator directory assistance failed to locate any patients not located by free internet sources. Additional websites had varied results. State driver's license records found 25 patients. Reunitetonight.com found none with thirty attempted. The best search engine was Intelius.com which located 68 out of 126 (54 percent) patients. CONCLUSION: The algorithm proposed by King et al. is not effective for long-term follow-up studies of pediatric populations. Intelius.com is worth the small fee charged (dollar 22.45) as it was the most effective method of locating patients.

Algorithms↗

Analysis of governmental Web sites on food safety issues: a global perspective.

Despite a growing concern over food safety issues, as well as a growing dependence on the Internet as a source of information, little research has been done to examine the presence and relevance of food safety-related information on Web sites. The study reported here conducted Web site analysis in order to examine the current operational status of governmental Web sites on food safety issues. The study also evaluated Web site usability, especially information dimensionalities such as utility, currency, and relevance of content, from the perspective of the English-speaking consumer. Results showed that out of 192 World Health Organization members, 111 countries operated governmental Web sites that provide information about food safety issues. Among 171 searchable Web sites from the 111 countries, 123 Web sites (71.9 percent) were accessible, and 81 of those 123 (65.9 percent) were available in English. The majority of Web sites offered search engine tools and related links for more information, but their availability and utility was limited. In terms of content, 69.9 percent of Web sites offered information on foodborne-disease outbreaks, compared with 31.5 percent that had travel- and health-related information.

Africa↗

Discovering biomedical relations utilizing the World-wide Web.

To crate a Semantic Web for Life Sciences discovering relations between biomedical entities is essential. Journals and conference proceedings represent the dominant mechanisms of reporting newly discovered biomedical interactions. The unstructured nature of such publications makes it difficult to utilize data mining or knowledge discovery techniques to automatically incorporate knowledge from these publications into the ontologies. On the other hand, since biomedical information is growing explosively, it is difficult to have human curators manually extract all the information from literature. In this paper we present techniques to automatically discover biomedical relations from the World-wide Web. For this purpose we retrieve relevant information from Web Search engines using various lexico-syntactic patterns as queries. Experiments are presented to show the usefulness of our techniques.

Classification↗

Nursing documentation with NANDA and NIC in a comprehensive HIS/EPR system.

DIPS nursing documentation system facilitates that nurses can write several types of notes into the EPR. Within these notes the nurses can register NANDA diagnoses and NIC interventions with nursing activities. To choose NANDA and NIC the nurse can use a search engine, or she can choose a relevant Care plan guideline and pick the suggested diagnoses and interventions from there. Diagnoses and interventions with nursing activities registered are presented in a Care plan. When a nurse writes a note for a patient she will always be presented the Care plan and she can easy evaluate and update the Care plan.

Documentation↗

Netting the evidence: finding pearls, not sewage.

The Internet is a powerful information resource that offers access to millions of files hosted on further millions of distributed computers. Unlike many information resources, however, the Internet focuses only on technical standards for information exchange. It does not address equally important concerns regarding the content and presentation of the information it displays. There is no editorial control, no unifying mechanism for maintenance or update, nor are there sanctions for the distribution of inaccurate and dangerous information. This overview seeks to guide the busy medical practitioner in their quest for high-quality research evidence. It stresses the value of key information management principles of focusing on the original question, filtering for high-quality sources and finding evaluated information. It briefly summarises the advantages and limitations of three important sources of information: one-stop shops, general search engines and scholarly gateways. Throughout the article, key points are highlighted through the use of a realistic problem-based scenario.

Databases, Bibliographic↗

[Two-dimensional gel electrophoresis analysis of moderately halophilic bacterium Halobacillus dabanensis D-8T under hypoosmotic shock condition].

Halobacillus dabanensis D-8T was isolated from the saline deposits of Daban lake in Xinjiang of China, and is able to grow in complex medium containing 0.5% to 25% salt. To figure out the survival mechanisms of Gram-positive moderately halophilic bacteria under hypoosmotic shock conditions, two-dimensional gel electrophoresis (2-DE) was carried out to investigate differential protein expression profiles of H. dabanensis D-8T in response to low osmotic challenge. The 2-D gels were stored as dry gels and their images were taken by ImageScanner and analyzed by Imagemaster 2D Platinum software. About 650 protein spots were detected in 2-D gel. Most of proteins were distributed in molecular mass of 17.5 - 66kDa and the range of isoelectric point 4.0 - 5.9. A total of 34 protein spots were found to alter their expression after strain D-8T was subjected to hypoosmotic shock from 20% to 0% salinity for 5 min and 50 min. Among them, the expression of 20 protein spots is up-regulated including 6 new protein spots, while that of 14 protein spots is down-regulated in answer to sudden osmotic down-shift. Protein spots of interest were excised from the gels and digested by trypsin. By means of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF/MS) and MASCOT search engine, 4 up-regulated protein spots were identified with peptide mass fingerprint, and are similar to heat shock protein DanK, rod shape-determining protein, penicillin-binding protein (PBP-1A) and 5-enolpyruvoylshikimate-3-phosphate synthase, respectively. Noticeably, PBP-1A firstly was up-regulated after shock of 5 min but disappeared after shock of 50 min. This indicated that the strain activate a minor mechanism of peptidoglycan synthesis to compensate the major synthesis mechanism for cells survival through a down-shift challenge. In addition, this paper was the first report that heat shock proteins were up-regulated in response to sudden osmotic down-shift.

Bacillaceae↗

[Contingent valuation for health care services. Review of domestic studies and outline of foreign investigations].

Contingent valuation method (CVM) can be applied to measure benefits of healthcare services. It is a technique for estimating subjects' willingness to pay (WTP) for a service under the scenario describing a virtual market with a questionnaire. In the present research, we outlined foreign studies and reviewed domestic studies on healthcare contingent valuation. A total of 14 papers from domestic literature (five English and nine Japanese articles) identified with mechanical search engines were verified for the following eight items: the method of the questionnaire; the information included in the virtual scenario; the question form for the willingness to pay; bias problems specific to CVM; validity/reliability, ex post/ex ante valuation, altruistic WTP, and non-health value. The following conclusions were drawn from the domestic studies: (1) several studies were short of sufficient information regarding the virtual scenario; (2) no research proved the existence of bias and the ways of coping with it; (3) tests for reliability were not carried out, although some kind of validity was verified; (4) all involved ex post user based evaluation; (5) neither altruistic WTP nor non-health value was examined. Taken the advantages of CVM into consideration, it should become a useful tool, complementing other economic evaluation techniques. Since its application has just begun in Japan, more emphasis needs to be given to practical issues so that healthcare workers will utilize CVM in a way that domestic studies in health economics will be activated.

Attitude to Health↗

A system for browsing the SNOMED International vocabulary.

We have developed a means for "browsing" an extremely large vocabulary of over 130,000 medical terms (SNOMED International, 3rd ed.). This vocabulary someday hopes to become a standard vocabulary and coding scheme for patient medical records. After obtaining the vocabulary in machine readable form (ASCII in standard data format--SDF) we wrote a meta program in Turbo Pascal which parsed and embedded control codes into an input file for importing the data into an "infobase" known as FolioVIEWS. Using this infobase, it became possible to rapidly and reliably navigate around the SNOMED vocabulary in a manner impossible with printed material. The FolioVIEWS search engine is robust and rapid and allows for easy access to the terms. The utility of the infobase in evaluating the SNOMED vocabulary has been quite good. The actual utility of SNOMED as a standard vocabulary remains to be evaluated.

Information Storage and Retrieval↗

Internet for teaching and learning introductory health informatics.

Internet resources seem attractive for teaching and learning. But are they usable and useful in their present form? We explored Internet, in particular its World Wide Web (WWW) resources, in a course on "Medical Methodology" (HINF270) for students of health information science. This course offers a systematic overview of the methodological principles of clinical care. Its broad scope and low depth makes this course a reasonable model to explore the limits of WWW resources. During the course, students wrote summaries of individual lectures. After critiquing and appropriate corrections, the texts were edited with Hypertext Mark-up Language (HTML) and augmented with links to WWW resources. Grading based on the papers, on their improvements through HTML and WWW, and on the provision of information on the search experience were incentives to use WWW. A formal questionnaire, administered on-line on a voluntary basis, concluded the investigation. Results show: 1) Even under considerable pressure to use WWW, libraries remain the reference source of choice for research; 2) Internet provides entertainment appeal even though practical utility is currently limited; 3) Technological proficiency with HTML and search engines is perceived as an asset; 4) Varying availability of Internet resources, uncertain and varying quality of sources, and limited specificity of research results are the major disadvantages of WWW. The teaching implications of these findings are discussed.

British Columbia↗

Florida physicians' guide to on-line information and the Internet.

The combination of new computing technology with progress in data communications over wide geographic areas offers computer users the opportunity to publish information to each other rapidly across wide geographic expanses. The concept of networking computers to gain access to the most recent and widest range of available information is consistent with the aims and methods of quality health care. The Internet is the ultimate extension to the computer network concept- an unlimited link of digital servers and users world-wide, united by common protocols for purposes of information exchange, self-policed and without central controls. Although the concept is attractive, on-line servers and the Internet are sophisticated information tools whose most effective use requires that users be oriented to basic concepts and conventions. This article summarizes the basic conventions in computer networking and data security; the differences in concept and use between bulletin board systems (BBSes), online systems, and the Internet for information access; the various classes of Internet information resources and their uses; the basic use of search engines to expedite information retrieval in the Internet; and offers practical advice in choosing methods of Internet access.

Computer Communication Networks↗

Role of Internet in medicine.

Internet, the largest network of connected computers, is becoming the ultimate frontier to access information for health providers. This review focus on how developments of this communication technology have become a useful educational resource in medicine, and describes modest ideas in computer network use. Internet basic resources are electronic mailing (E-mail), discussion groups, file transfer, and browsing the World Wide Web (WWW). E-mail brings physicians with common interest together. Surgeons employ it as a communicating tool. Legal and social responsibility is bounded with its use. Discussion groups permits debate including clinical cases, operations, techniques research, career opportunities, and meetings. File transfer provides the opportunity of retrieving archives from public libraries. The WWW is the most resourceful tool due to its friendly interface and ease of navigation. The average physician needs to know almost nothing on how computers work or where they came from to navigate through this pandemonium of information. Click and play with today graphical applications encourage the computer illiterate to connect. Establishing the connections envelops the need of hardware, software and a service provider. Future development consists of online journals with new ideas in peer-review and authentication, telemedicine progression, international chatting, and centralization of cyber space information into database or keyword search engines.

Computer Communication Networks↗

Searching for information on the World Wide Web--a guide for dental health professionals: Part 1.

Mastering the retrieval of valid information from the Internet can be challenging, especially for busy professionals with little time for learning the necessary techniques. This article provides a conceptual framework for browsing and searching for clinically relevant, valid information on the Web. Part 1 provides an overview of the Web that includes information on access methods, general characteristics, and the main user interface (a browser). Concerns about information validity are also discussed. Part 2 will describe several common methods for searching the Web, including how to visit a web site directly, visit a directory site, and conduct a search via a search-engine site.

Computer Communication Networks↗

[Electronic forum of Revista de neurología: 'Internet, Medicine and Neuroglia'].

INTRODUCTION: In recent years Internet has drastically transformed the world of telecommunications. Questions about whether Internet and the global communication accessibility may be considered as a fundamental aspect in the medicine of today and tomorrow have been brought up. OBJECTIVE: Discuss current and future applications of Internet to the field of Medicine and Neurology. METHODS: Bibliographical review based on Medline and standard Web search engines. Forum sessions performed through Internet by means of Web-Chat. Forum coordination entirely performed by electronic mail. RESULTS: There are several opinions regarding the influence of Internet on Medicine and Neurology. Currently, the communication and collaboration between teams is improving. It allows scientific publications on-line, improves continuous remote training and facilitates information to patients. New applications like telemedicine need more development. CONCLUSIONS: Currently, Internet represents an efficient tool for collaboration, training and distribution of information in the field of Medicine and Neurology.

Humans↗

Searching online and Web-based resources for information on natural products used as drugs.

Finding and evaluating information on natural products used as drugs can present challenges to the information professional. In this study, eight databases including resources retrieved on the Web were compared for relevancy and uniqueness. Ten reference questions related to natural products used as drugs were searched in the latest three year file of a number of databases, including MEDLINE, International Pharmaceutical Abstracts, and EMBASE/Excerpta Medica. In addition, the Web was searched for relevant Internet sites using the Alta Vista search engine. EMBASE/Excerpta Medica retrieved the largest number of relevant citations for four of the ten questions. MEDLINE, the Health Reference Center, and Alta Vista each retrieved the largest numbers in two questions. Overall, the standard medical databases were the first choice for the health professional and for many lay people because of their more extensive indexing and coverage of authoritative journals.

Complementary Therapies↗

Evaluating overall usage of a digital health sciences library.

BACKGROUND: Digital health sciences library (DHSL) evaluation involves studying the usage of the DHSL by individuals as well as populations. The purpose of this study was to evaluate trends in overall usage of a DHSL as part of a process of continuous quality improvement in order to learn how to enhance a DHSL in order to meet its users' needs better. METHODS: Web server log file analysis was performed on a prototype DHSL, the Virtual Hospital, using two log file analysis programs on data from the month of February over four consecutive years, 1995 to 1998. RESULTS: Overall DHSL usage increased between 1995 and 1997 and leveled off in 1998. Fifteen percent of usage came from countries outside the United States. A broad spectrum of medical information for health care providers and patients was accessed and centered around specialty medical information. CONCLUSIONS: To be of optimal assistance to users, DHSLs should (1) contain a broad base of information on common and uncommon medical problems, (2) accommodate the needs of the significant percentage of users that are international through content translation and mirroring, and (3) ensure they are indexed and catalogued in the major Web search engines and Web general and medical indices so they can be easily found by users.

Evaluation Studies as Topic↗