Skin histamine levels in chronic atopic dermatitis.
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The causes leading to occupational contact eczema were compared in two time periods 1972-1978 and 1979-1987. An increase was observed in the second period in the frequency of occupational eczema in women and greater incidence in health service workers. Occupational contact eczema was diagnosed most frequently in construction workers, in machinery and metallurgic industry and in weavers and textile workers. The causes of occupational eczema remained unchanged, the most frequent causes were still hypersensitivity to chromium, cobalt and epoxy resins. No increase in the frequency of hypersensitivity to nickel was noted.
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