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At least 919 records · Page 51Linked to original sources

Has conventional sphygmomanometry ended with the banning of mercury?

The banning of mercury from clinical practice will lead to the inevitable demise of traditional clinical sphygmomanometry. There are differences in approach to this important issue between European countries on the one hand, which generally have accepted that the mercury sphygmomanometer must be replaced with alternative devices, and the U.S. on the other, where the view is that the mercury sphygmomanometer should remain as the mainstay of blood pressure measurement. The availability of alternative devices for the mercury sphygmomanometer is improving but the problem of independent validation is a serious issue, which is being addressed by the European Society of Hypertension Working Party on Blood Pressure Monitoring, which has drafted an International Protocol for validating blood pressure measuring devices. The removal of the mercury sphygmomanometer from clinical practice has other implications, which merit careful consideration; the advent of automated devices must lead inevitably to the disappearance of the traditional clinical auscultatory technique of blood pressure measurement, and with the disappearance of mercury it will be argued that the Système International(SI) unit of measurement -- the kilopascal -- should replace the millimetre of mercury.

Auscultation↗

[Diagnostics and management of central venous line infections in pediatric cancer patients].

Otherwise unexplained clinical signs of infection in patients with tunneled or totally implanted central venous access devices (CVAD) are highly suspicious of an underlying CVAD-associated infection. Diagnostic methods include catheter swabs, blood cultures and cultures of the catheter tip or port reservoir. In case of a suspected CVAD-related blood stream infection in pediatric cancer patients in situ treatment without prompt removal of the device can be tried. The removal of the CVAD should be considered, if bacteremia persists or relapses 72 hours or longer after the initiation of an (in vitro effective) antibacterial therapy administered through the line. The CVAD should be removed even earlier, if the patient suffers from hypotension or other signs of severe organ dysfunction related to the infection. If S. aureus, Pseudomonas aeruginosa, multiresistant Acinetobacter baumannii or Candida spp.are isolated from blood cultures taken through a CVAD, patients are at a high risk for severe complications and immediate device removal is also recommended. Duration of therapy depends on the immunological recovery of the patient (neutrophils counts), the pathogen isolated and on the presence of related complications like thrombosis, pneumonia, endocarditis, osteomyelitis. Antibiotic-lock techniques in addition to systemic treatment are beneficial in Gram-positive infections. Although prospectively controlled studies are missing, the concomitant use of urokinase- or taurolidine seems to favour catheter salvage.

Antineoplastic Agents↗

Pacemaker dependent patients with device infection--a modified approach.

A modified surgical concept for temporary cardiac pacing in pacemaker dependent patients requiring total removal of infected devices is presented. Proximal to the infected pocket a permanent bipolar pacing lead is placed transcutaneously into the ipsilateral subclavian or jugular vein. The lead is placed in the right ventricle and fixed into the skin using the suture sleeve. Pacing is established by connecting an external pacing generator. Subsequently the infected device can be removed completely. After wound dressing the externalized lead is connected to a permanent VVI-pacemaker allowing for prolonged temporary pacing.

Aged↗

Metallic implant removal in children.

The indications for removing metal that was implanted in children and the practice of removing it have changed dramatically during the past century, but this subject is rarely discussed in publications, oral presentations, or resident training curricula. Thus, during their training, residents learn about the topic only sporadically from evaluating patients. This article presents the cases for and against metallic implant removal and identifies situations in which removal is appropriate and situations in which it is not.

Bone Nails↗

Symptomatic plate removal in maxillofacial trauma: a review of 76 cases.

This study reviewed the fate of titanium plates used to correct maxillofacial trauma in 76 patients to define risk factors for plate removal. Medical records of 76 consecutive patients at a single institution, over a 10-year period, were retrospectively reviewed. Variables included age, sex, trauma type, diagnosis, fracture type, fracture diagnosis, plate location, surgical approach, and reasons for plate removal. Fracture diagnosis was described as panfacial (42%), blowout (3%), midface (28%), zygoma (26%), mandible angle (6%), ramus (7%), and symphysis (9%). All plate removals according to fracture diagnosis were in the mandible angle (30%) and symphysis (20%). When plate location was reviewed, 68% of the plates were placed in the upper and midface and 32% were placed in the mandible. Specifically, plates were placed in the frontozygomatic suture (18%), zygomaticomaxillary suture (19%), infraorbital rim (14%) and mandible symphysis (15%), mandible angle (9%), piriform (6%), nasal (5%), mandible ramus (4%) and body (4%), zygoma (2%), and frontal (2%). Of 163 plates that were placed, 6 plates (3.7%) were removed. Three (12%) of the symphysis plates and 3 (20%) of the angle plates were removed. Among all variables, only fracture diagnosis (P = 0.01) and plate location (P = 0.01) were statistically significant in plate removal. Five plates were removed for abscess/infection; 1 plate was removed for osteomyelitis. Further review revealed that 4 out of 6 plates removed involved synchronous mandible fractures. Most infections after maxillofacial trauma occur in the mandible, and often these infections are the main reason for plate removal. More vigilance is needed in the treatment of mandible angle and symphyseal fractures, especially if there are synchronous fractures, to prevent infection, plate removal and subsequent malunion.

Adult↗

Removal of a retained Herbert-Whipple screw with use of the Osteochondral Autograft Transfer System (OATS) core harvester: a case report.

After a revision procedure is performed to address a full-thickness chondral defect of the knee, hardware removal can be challenging. We describe using a core harvester, the Osteochondral Autograft Transfer System (OATS; Arthrex, Naples, Fla), to remove a Herbert-Whipple screw placed earlier in a failed attempt to fix an osteochondritis dissecans lesion on the lateral aspect of the medial femoral condyle. This hardware removal technique can be performed either arthroscopically or in an open fashion and may also be used with other revision procedures (ie, revision anterior cruciate ligament reconstruction) in which an embedded, poorly visualized, or stripped screw must be removed.

Adult↗

Non-invasive densitometric and histomorphometric study of the regenerated bone in the distraction gap in rabbits.

The long period of external fixation after the completion of distraction, which is necessary to obtain enough strength for resisting without fixation is a significant disadvantage of distraction osteogenesis. The purpose of this study is to understand the mechanical property of the regenerated bone and try to find an appropriate timing for safely removing the fixation device. An external fixation device was applied to the right tibia in rabbits and transverse osteotomy was performed just below the tibio-fibula junction. The tibiae were lengthened 7.2 mm at 0.72 mm a day for 10 days after surgery. A bone mineral density (BMD) and stress strain index (SSI) analyzed by peripheral quantitative computed tomography showed a significant increase on day 40, but returned to the control level at day 64 after the completion of distraction. Therefore, the newly formed bone between the host cortical bone seemed to be enough to resist the mechanical stress on day 40 during the consolidation period in this study. The present results suggested the possibility of removing the fixation device during the period when the BMD and SSI showed a significantly high level during the consolidation period.

Absorptiometry, Photon↗

The effect of a 10 cm2, 0.5% 15-ME-PGF2alpha methyl ester intravaginal silastic device on abortion and plasma prostaglandin concentration.

Intravaginal insertion of a 10 cm2 silastic device with an 0.5% concentration of 15(S)-15-methyl-prostaglandin F2alpha methyl ester alone successfully induced abortion in 27 of 48 patients in the midtrimester and in an additional 11 patients with a concomitant infusion of oxytocin. The mean abortion time for the 38 successful induction was 15.35 hours. In 8 of the 10 patients who failed to abort even with concomitant oxytocin therapy, abortion was induced by serial intramuscular injections of 15-ME-PCF2alpha; the remaining 2 failures underwent surgical evacuation. The plasma levels of 15-ME-PGF2alpha methyl ester in the 11 patients studied varied widely over the first 2 hours after insertion of the device. The maximum mean level was achieved at 2 hours, maintained at 4 hours and then dropped sharply at 8 hours and declined over the abortion period in undelivered patients. Vomiting and diarrhea were the most common side effects and in general well tolerated by the patients. However, there was an adverse reaction in a single patient who experienced almost constant nausea, vomiting and diarrhea. The device was removed 1 hour 50 minutes after insertion and the patient aborted spontaneously 7 hours later. Intravaginal insertion of a silastic device is an effective means of prostaglandin abortion, but further investigation is required to determine the most effective device which would provide a slow, continuous release of the prostaglandin.

Abortion, Induced↗