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Comparison of physiological responses to morning and evening submaximal running.

The aim of this study was to assess the effect of time of day on physiological responses to running at the speed at the lactate threshold. After determination of the lactate threshold, using a standard incremental protocol, nine male runners (age 26.3 +/- 5.7 years, height 1.77 +/- 0.07 m, mass 73.1 +/- 6.5 kg, lactate threshold speed 13.6 +/- 1.6 km x h(-1); mean +/- s) completed a standardized 30 min run at lactate threshold speed, twice within 24 h (07:00-09:00 h and 18:00-21:00 h). Core body temperature, heart rate, minute ventilation, oxygen uptake, carbon dioxide expired, respiratory exchange ratio and capillary blood lactate were measured at rest, after a warm-up and at 10, 20 and 30 min during the run. In addition, the rating of perceived exertion was reported every 10 min during the run. Significant diurnal variation was observed only for body temperature (36.9 +/- 0.9 degrees C vs 37.3 +/- 0.3 degrees C) and respiratory exchange ratio at rest (0.86 +/- 0.01 vs 0.89 +/- 0.07) (P < 0.05). Diurnal variation persisted for body temperature throughout the warm-up (37.1 +/- 0.2 degrees C vs 37.5 +/- 0.3 degrees C) and during exercise (36.2 +/- 0.6 degrees C vs 38.6 +/- 0.4 degrees C), but only during the warm-up for the respiratory exchange ratio (0.85 +/- 0.05 vs 0.87 +/- 0.02) (P < 0.05). The rating of perceived exertion was significantly elevated during the morning trial (12.7 +/- 0.9 vs 11.9 +/- 1.2) (P < 0.05). These findings suggest that, despite the diurnal variation in body temperature, other physiological responses to running at lactate threshold speed are largely unaffected. However, a longer warm-up may be required in morning trials because of a slower increase in body temperature, which could have an impact on ventilation responses and ratings of perceived exertion.

Adult↗

Changes in muscle activity with increasing running speed.

Electromyographic (EMG) activity of the leg muscles and the ground reaction forces were recorded in 17 elite male middle-distance runners, who performed isometric maximal voluntary contractions (MVC) as well as running at different speeds. Electromyograms were recorded from the gluteus maximus, vastus lateralis, biceps femoris, gastrocnemius and tibialis anterior. The results indicated that the averaged EMG (aEMG) activities of all the muscles studied increased (P < 0.05) with increasing running speed, especially in the pre-contact and braking phases. At higher speeds, the aEMG activities of the gastrocnemius, vastus lateralis, biceps femoris and gluteus maximus exceeded 100% MVC in these same phases. These results suggest that maximal voluntary contractions cannot be used as an indicator of the full activation potential of human skeletal muscle. Furthermore, the present results suggest that increased pre-contact EMG potentiates the functional role of stretch reflexes, which subsequently increases tendomuscular stiffness and enhances force production in the braking and/or propulsive phases in running. Furthermore, a more powerful force production in the optimal direction for increasing running speed effectively requires increased EMG activity of the two-joint muscles (biceps femoris, rectus femoris and gastrocnemius) during the entire running cycle.

Adult↗

Skinfold thicknesses associated with distance running performance in highly trained runners.

It has been postulated that additional adiposity has a negative effect on performance in heterogeneous groups of runners. Previous studies have not tested this hypothesis in homogeneous groups of elite runners. The purpose of this study was to determine whether the sum of skinfold thicknesses and specific single skinfold sites were related to competitive running performance in homogeneous groups of male and female elite athletes. In total, 184 top-class runners (130 males and 54 females) volunteered to participate in the study. Skinfolds were measured at the following sites: biceps, triceps, subscapular, pectoral, iliac crest, abdominal, front thigh and medial calf. Runners were classified into groups in accordance with their best performance times. Correlation analysis and partial correlation coefficients that controlled for age and weight were applied to each single skinfold, the sum of six skinfolds (excluding biceps) and the extremity (sum of triceps, front thigh, medial calf) to trunk (sum of subscapular, iliac crest, abdominal) ratio and performance. Performance was rated by the scoring procedures of the International Amateur Athletics Federation. In male runners, the pectoral, iliac crest, abdominal, biceps, triceps, subscapular skinfolds and the sum of six skinfolds were not associated with performance score for any of the distances. High correlations were found between the front thigh (r = 0.78, P = 0.000) and medial calf (r = 0.55, P = 0.018) skinfolds and 1500 m run time, and between the front thigh (r = 0.59, P = 0.014) and medial calf (r = 0.57, P = 0.017) skinfolds and 10,000 m run time. In female runners, the front thigh and medial calf skinfolds were highly correlated with 400 m run time (r = 0.71, P = 0.022 and r = 0.81, P = 0.005, respectively). The results of this study indicate that skinfold thicknesses in the lower limb are positively associated with running time over several distances, and may be a useful predictor of athletic performance.

Adult↗

Effect of aqua exercise on recovery of lower limb muscles after downhill running.

The aim of the present study was to examine how the recovery of physiological functioning of the leg muscles after high-intensity eccentric exercise such as downhill running could be promoted by aqua exercise for a period until the damaged muscle had recovered almost completely. Ten male long-distance runners were divided equally into an aqua exercise group and a control group. From the first day (Day 0) to the fourth day (Day 3), the participants completed a questionnaire on muscle soreness, and serum creatine kinase activity, muscle power, flexibility, whole-body reaction time and muscle stiffness were measured. After measurements on Day 0, the participants performed downhill running (three 5 min runs with a 5 min rest interval at -10%, 335.7 +/- 6.1 m . min-1). The aqua exercise group performed walking, jogging and jumping in water on three successive days following the downhill running on Day 0 for 30 min each day. Muscle power was reduced on Day 1 in the control group (P < 0.05). Muscle soreness in the calf on Day 3 was greater in the control group than that in the aqua exercise group (P < 0.05). In the aqua exercise group, muscle stiffness in the calf was less than that in the control group over 4 days (time main effect: P < 0.05; group x time interaction: P < 0.05). We conclude that aqua exercise promoted physiological functioning of the muscles in the legs after high-intensity downhill running for a period until the damaged muscles had recovered almost completely.

Adult↗

The effect of marathon running on carnitine metabolism and on some aspects of muscle mitochondrial activities and antioxidant mechanisms.

Carnitine is an essential co-factor in the catabolism of fats as an energy source. The primary purpose of this study was to investigate the effect of running a marathon on the metabolism of carnitine by endurance-trained athletes, and to evaluate the effect of carnitine administration on the performance of such exercise. The effects of marathon running on mitochondrial enzymes and cellular anti-oxidants were also examined to assess whether the expression of these activities is altered by exercise. Subjects were 10 experienced male marathon runners aged between 19 and 25 years. Running a marathon caused a fall in the plasma content of unesterified carnitine (37%) and an increase in the level of acetylcarnitine present (288%). Loading of the athletes with L-carnitine for 10 days before running a marathon abolished the exercise-induced fall in plasma-free carnitine (P less than 0.05) whilst amplifying the production of acetylcarnitine (P less than 0.05). Carnitine loading of the athletes studied made no detectable improvement in performance of the marathon (P greater than 0.05). Cytochrome oxidase, succinate cytochrome C reductase and superoxide dismutase activities present in skeletal muscle were unaltered by marathon running. However, such exercise caused a large increase in the tissue content of oxidized glutathione (189%) at the expense of reduced glutathione (-18%).

Acetylcarnitine↗

Influence of ingesting a carbohydrate-electrolyte solution on endurance capacity during intermittent, high-intensity shuttle running.

The aim of this study was to examine the effects of ingesting a carbohydrate-electrolyte solution on endurance capacity during a prolonged intermittent, high-intensity shuttle running test (PIHSRT). Nine trained male games players performed two exercise trials, 7 days apart. On each occasion, they completed 75 min exercise, comprising of five 15-min periods of intermittent running, consisting of sprinting, interspersed with periods of jogging and walking (Part A), followed by intermittent running to fatigue (Part B). The subjects were randomly allocated either a 6.9% carbohydrate-electrolyte solution (CHO) or a non-carbohydrate placebo (CON) immediately prior to exercise (5 ml kg-1 body mass) and every 15 min thereafter (2 ml kg-1 body mass). Venous blood samples were obtained at rest, during and after each PIHSRT for the determination of glucose, lactate, plasma free fatty acid, glycerol, ammonia, and serum insulin and electrolyte concentrations. During Part B, the subjects were able to continue running longer when fed CHO (CHO = 8.9 +/- 1.5 min vs CON = 6.7 +/- 1.0 min; P < 0.05) (mean +/- S.E.M.). These results show that drinking a carbohydrate-electrolyte solution improves endurance running capacity during prolonged intermittent exercise.

Adult↗

Accumulated oxygen deficit and shuttle run performance in physically active men and women.

The aim of this study was to establish the validity of using shuttle run performance over 20 m to predict accumulated oxygen deficit. A new high-intensity shuttle run test (HIST) was devised, during which subjects ran to exhaustion at a speed equivalent to 120% of their performance attained during a progressive shuttle run test. The reliability of the new test was examined and found to be acceptable for 18 subjects who performed the test twice on separate days (r = 0.84, P < 0.01, study I). The discriminating ability of the new test was examined by comparing the distance covered by eight sprint- and eight endurance-trained athletes at 120% of their respective progressive shuttle run performances (615 +/- 111 vs 273 +/- 84 m, P < 0.01, study II). The strongest predictor of accumulated oxygen deficit for 27 subjects was found to be the geometric mean of the performances on the new test and on the progressive shuttle run test (r = 0.74, study III). The regression equation for this relationship was then used to estimate the accumulated oxygen deficit for a second group of 16 subjects (study IV). The correlation between the estimated and measured accumulated oxygen deficits was significant (r = 0.79, P < 0.01). The results from studies III and IV were therefore combined with the data from six new subjects to give a regression equation for predictive purposes based on 49 subjects.

Adult↗

Optimising the trans-femoral prosthetic alignment for running, by lowering the knee joint.

For amputees to perform an everyday task, or to participate in physical exercise, it is crucial that they have an appropriately designed functional prosthesis. The aim of this study was to investigate the optimal trans-femoral prosthetic alignment configuration for running. A case study design was implemented as the method to collect data on four male Paralympic level trans-femoral amputee runners. In total 28 synchronised 3D kinematic, kinetic, and temporal biomechanical measures were analysed. A new prosthetic alignment, in which the prosthetic knee axis was lowered longitudinally (moved distally), was evaluated for running. The performance of the symmetry indices and running time for a total of three new modified alignments were compared to the standard prosthetic alignment. The interlimb asymmetry was found to improve when the subjects ran on the modified prosthetic alignment, and most importantly a one way ANOVA found a statistically significant increase in running velocity. This study identified that for all four subjects, who used the same prosthetic components, lowering the prosthetic knee joint centre improved their interlimb symmetry, and subsequently their running velocity by an average of 26%.

Adult↗

Visual guidance during competition performance and run-through training in long jumping.

To ensure precise foot placement on the take-off board, long jumpers visually regulate their stride pattern during their run-up. A relationship between how much visual guidance they use and the horizontal distance they jump has not, however, been quantified. Run-up precision is often practiced using run-throughs, which exclude the take-off and, therefore, the high physical stress of the complete long jump. The validity with which this common training method simulates the long jump approach remains, however, to be verified. Four state-standard long jumpers and two heptathletes completed two sessions, each comprising six runthroughs and six competition long jumps. A 50 Hz video camera was manually panned from an elevated platform to film each trial, to enable subsequent gait characteristic evaluations. Linear regression analyses identified that a longer visual regulation phase, measured in time, distance or number of strides, was a key predictor of long jump distance. The number of strides that were visually regulated during the long jump approach was, accordingly, positively correlated with long jump distance (r = 0.67, p = 0.001). The amount of visual regulation used during run-throughs was, however, less than half (p = 0.001) of that observed during long jump approaches. Our results should compel long jump coaches to supplement run-through training with additional visual guidance exercises, to encourage their athletes to visually regulate more of their long jump approach.

Adult↗

Negative energy balance induced by voluntary wheel running inhibits polyp development in APCMin mice.

Treadmill running of approximately 0.9 km/day has had inconsistent effects on spontaneous intestinal polyp development in C57BL/6J-Apc(Min)/J (Min) mice; the amount of energy expenditure and/or a lack of hormonal changes could account for this variability. The purpose of this study was to examine the effects of a negative energy balance induced by voluntary wheel running on polyps, insulin-like growth factor-1 (IGF-1) and corticosterone in Min mice. Seven-week-old male Min mice were randomly assigned to control (CON, n = 23) or wheel running (EX, n = 24) conditions for a 10-week study period. All mice had water and AIN-76A diet ad libitum for the first approximately 3 weeks on study, after which the EX group was pair-fed to the CON group to maintain a negative energy balance due to the exercise. EX mice voluntarily ran 3.8 km/day (2.7-6.0 km/day) (median, interquartile range) and weighed less than CON mice throughout the study. More CON mice died before the end of the study versus EX mice (26 versus 0%, P < 0.01). CON mice had significantly more polyps versus EX mice (21.6 +/- 1.5 versus 16.9 +/- 2.0, P < 0.01; mean +/- SE), and daily running distance in EX was inversely correlated with total polyp number (r = -0.70, P < 0.01). Urinary corticosterone output (P < 0.01) and serum IGF-1 were significantly higher in EX than CON (P < 0.001); however, total polyp number was unrelated to corticosterone (r = 0.05, P = 0.84) and IGF-1 (r = -0.01, P = 0.93). In this study, a negative energy balance produced by wheel running exercise and restricted feeding decreased polyp burden in male Min mice and appeared to have a dose-response effect on polyp number. Although EX affected IGF-1 and corticosterone, neither marker was related to total polyp number.

Animals↗

The inability of hormone replacement therapy or chronic running to maintain bone mass in master athletes.

BACKGROUND: Previous studies have demonstrated equivocal findings on the effect of chronic running on bone mass in post-menopausal women. The purpose of this study was to determine the effect of chronic running alone and in conjunction with hormone replacement therapy (HRT) on bone mineral density (BMD) in postmenopausal women. METHODS: Forty-three women [15 premenopausal 48.1 +/- .4 yrs (Pre); 13 postmenopausal 57.3 +/- 2.3 yrs (Post); and 15 HRT-treated postmenopausal 56.8 +/- 1.5 yrs (PostE)] served as subjects. All were chronic runners (duration > 5 yrs, > 10 miles per week). BMD was determined by dual energy x-ray absorptiometry, VO2 max on a treadmill, body composition by hydrostatic weighing, knee strength by KinCom dynamometer, and training and menstrual history by questionnaire. Analysis of covariance with Tukey post hoc tests was utilized to compare the groups. RESULTS: The groups were similar in body weight, VO2 max, years training, and miles run per week. Pre and PostE did not differ in total or spine BMD. However, Pre had greater hip BMD than PostE (.973 +/- .03 vs .876 +/- .03 g/cm2; p < .05). As well, Pre had greater BMD of the hip (.973 +/- .03 vs .805 +/- .03 g/cm2; p < .05), spine (1.047 +/- .04 vs .870 +/- .04 g/cm2; p < .05), and total body (1.115 +/- .02 vs .996 +/- .03 g/cm2; p < .05) than Post. CONCLUSIONS: These results suggest that (a) chronic running + HRT is insufficient to protect hip BMD and (b) chronic running alone provides no protection for bone mass in postmenopausal women.

Analysis of Variance↗

Determining predictor variables for running-related pain.

The purpose of this study was to determine whether specific predictor variables exist for particular running-related injuries. Data on 134 patients with running-related injuries were evaluated to establish the factors that were associated with specific pain sites. Patient data consisted of a brief running history and measurements of 72 anatomical variables that have been cited in the literature as predisposers to running-related injuries. The descriptive statistics indicated certain associations of variables with each pain group. A factor analysis was used to eliminate multicollinearity and to reduce the 72 variables to 9 factors. The results of a discriminant function analysis using factor scores indicated that patients' membership in one of six pain groups could be predicted correctly in 29.1% of the cases. We concluded that the factors used in this study were not good predictors of pain groups. Physical therapists, however, should publish their data on runners' injuries, treatment, and rehabilitation to supplement the published data that relate anatomical and biomechanical factors to running-related injuries.

Athletic Injuries↗

Differential effects of vestibular stimulation on walking and running.

Prompted by our recent observation that an acute vestibular tone imbalance causes less deviation from the intended path when running than when slowly walking, we examined 10 healthy subjects when walking or running at different step frequencies during galvanic vestibular stimulation. Blindfolded subjects were asked to walk (1 Hz step frequency) or run (3 Hz step frequency) straight ahead toward a previously seen target. The mean gait deviation after 10 s was 6.0 +/- 2.4 degrees at 1 Hz and 2.8 +/- 1.8 degrees at 3 Hz step frequency (n = 10; p < 0.001, paired t-test). In a second experiment walking and running in place were investigated. There was no significant difference in body displacement. Walking and running are highly automated processes based on spinal locomotor generators that are under supraspinal control. We conclude that vestibular input is differentially regulated depending on the locomotion speed and pattern used.

Adult↗

Effects of verapamil and atenolol on exercise tolerance in 5,000 m cross-country running: a double-blind cross-over study in normal humans.

The effects on exercise tolerance of 7-day treatment with a calcium channel blocker, verapamil 160 mg twice daily (b.i.d.), and a beta 1-selective blocker, atenolol 50 mg b.i.d., were compared in 10 healthy and physically active young subjects in 5,000-m cross-country running at high intensity. The study was a double-blind cross-over trial. Comparison was made with a single-blind placebo as well. Performance time was measured every 1,000 m in seven 5,000-m runs, in which subjects were instructed to keep to a constant fatigue perception (Borg scale rating). Both drugs significantly (p = 0.001) increased the performance time over the first 1,000 m as compared with placebo. However, running time after 1,000, 2,000, and 3,000 m was prolonged significantly less (p less than 0.05) by verapamil than by atenolol. For the entire 5,000-m run, atenolol caused a significant increase (p = 0.001) in mean running time by 1 min 34 s (i.e., 7.5%; 95% confidence interval 48 s to 2 min 21 s) as compared with placebo, whereas verapamil caused no significant change (+46 s).

Adult↗

Changes in VO2max and maximal treadmill time after 9 wk of running or in-line skate training.

This study tested the hypothesis that running and in-line skating training elicit similar improvements in cardiorespiratory fitness. Changes in maximal oxygen consumption (VO2max) and maximal treadmill endurance time were compared in runners (N = 16), in-line skaters (N = 19), and controls who did no systematic training (N = 7). Training volumes were similar for runners and skaters (3 d.wk-1, 10-40 min/session, 80-90% of exercise specific maximal heart rate) and included both continuous and interval workouts. Pre- and post-training VO2max and maximal treadmill time were measured in all subjects using a running protocol and in skaters using an in-line skating protocol. The groups did not differ in pre-training running VO2max or maximal treadmill time. After 9 wk, significant increases in running VO2max and maximal treadmill time were observed in runners (mean +/- SE, 9.3 +/- 1.3%, 14.9 +/- 2.5%) and skaters (6.6 +/- 1.0%, 9.1 +/- 3.4%), but not controls. Skaters also significantly increased their skating VO2max and maximal treadmill time (8.6 +/- 1.8%, 7.9 +/- 2.9%). The magnitude of these increases was not different between the two training groups. In conclusion, in moderately active college-aged students, similar improvements in VO2max are achieved with running and in-line skating programs that are equivalent in training volume and intensity.

Adult↗

The gender difference in distance running performance has plateaued: an analysis of world rankings from 1980 to 1996.

PURPOSE: Annual world rankings from 1980-1996 were used i) to determine if the gender difference in distance running events has stabilized, and ii) to examine whether the relative decline in pace as race distance increases is different between men and women. World best (WB) and 100th best times in the 1500 m and the marathon (42 km) for each of the 17 years were the indices used to represent overall trends in men's vis-à-vis women's distance running. METHODS: These data were analyzed using regression analyses to develop and compare gender-specific equations. In the 1500 m, the gender difference in WB times (11.1 +/- 1.1%) was consistent from 1980 to 1996, and the slight rate of improvement in event depth (i.e., 100th rankings) was similar for men and women. RESULTS: In the marathon, the gender difference in WB times (11.2 +/- 0.9%) was essentially the same as for the 1500 m. In 1980, the marathon was a fairly new event for the women, having only just been sanctioned by the International Amateur Athletics Federation (IAAF). As a consequence, the depth of the field increased quickly from 1980 to 1984. Since the mid-1980s, the rate of improvement for women in 100th-ranked times has leveled off to equal that of men. The average declines in relative pace for men and women from the 1500 m to the 10 km to the marathon were found to be remarkably similar with no diminishing of the gender difference as race distance increased. CONCLUSIONS: Based on worldwide indices of competitive distance running, the gender difference in distance running performance has plateaued in recent years. Concomitantly, over the past decade, opportunities for women to train and compete have approached parity with those of men. It is likely that the current gender difference in performance will remain fairly constant because of biological differences between men and women that give men an advantage in distance running.

Databases as Topic↗

An analysis of hip joint loading during walking, running, and skiing.

PURPOSE: It was the purpose of this study to investigate loading of the hip joint during various skiing activities and to compare the results with walking and running. The results are relevant to determine which skiing activities can be recommended for patients after total hip replacement. METHODS: Nine male subjects were instrumented with a 12-channel accelerometer system mounted on the upper body. Data were collected during walking, running, and six skiing activities and used as input for an inverse dynamic analysis that resulted in the time histories of the intersegmental force and moment at the supporting hip joint. Joint contact force was computed using a simple muscle model. Peak values were determined, averaged over all loading cycles, and compared between activities. RESULTS: Intersegmental force, indicating the influence of upper body weight and accelerations, was highest during running. Intersegmental moments were highest during the alpine skiing activities and indicated large extensor muscle forces at the hip joint. The peak joint contact force during walking at 1.5 m x s(-1) was 2.5+/-0.3 times body weight (BW). Running at 3.5 m x s(-1) produced a joint contact force of 5.2+/-0.4 BW during the push-off phase. Joint contact forces during four different alpine skiing conditions ranged from 4.1+/-0.6 BW (long turns, flat slope) to 7.8+/-1.5 BW (short turns, steep slope). Cross-country skiing had lower hip joint loading than running but higher than walking: 4.0+/-1.1 BW for classical technique and 4.6+/-0.6 BW for skating technique. CONCLUSIONS: Assuming that walking is a "safe" activity for a hip prosthetic patient, controlled alpine skiing and cross-country skiing appear relatively safe with respect to the magnitude of loading. However, the skiing activities showed considerably higher mediolateral and anterior-posterior forces than walking. Mechanical testing of prosthetic devices with loading conditions specific to these activities is needed to assess the effect of these force components on hip prostheses and to allow interpretation with respect to potential effects of skiing for a hip prosthetic patient.

Adult↗

The energy cost of horizontal walking and running in adolescents.

PURPOSE: This study developed and cross-validated generalized equations for predicting VO2 (mL x kg(-1) x min(-1)) and caloric expenditure (kcal x kg(-1) x min(-1)) during horizontal walking and running in adolescents. METHODS: Subjects were 47 male and 35 female adolescent volunteers, ages 12-18. Each subject underwent a submaximal treadmill exercise test to determine VO2 at randomly selected walking and jogging speeds (67-215 m x min(-1)). Caloric expenditure was estimated from VO2 and RER. Multiple regression was used to develop prediction equations for estimating VO2 and caloric expenditure from a derivation sample of 77 random observations, both walking and running. RESULTS: The group relationship between running speed and energy cost in the derivation sample was linear, whereas the relationship between walking speed and energy cost was quadratic. Gender, age, and height each failed to account for significant additional variation in energy cost after speed and mode were considered. Skinfolds accounted for a small yet significant amount of additional variation in energy cost. The derived equations were cross-validated on a sample of 76 separate random observations. The cross-validation statistics are: for VO2, R = 0.95, error = 3.58 mL x kg(-1) x min(-1), and for caloric expenditure, R = 0.94, error = 0.019 kcal x kg(-1) x min(-1). Most selected adult equations consistently underestimated both VO2 and caloric expenditure in the cross-validation sample. CONCLUSIONS: These results suggest that in adolescents, within the range of speeds tested, the relationship between speed of movement and energy cost for running is linear, but for walking is curvilinear. Also, adult models for estimating VO2 or caloric expenditure do not account for the higher relative energy cost of walking and running in adolescents.

Adolescent↗