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Proximal femoral resection-interposition arthroplasty: salvage hip surgery for the severely disabled child with cerebral palsy.

The treatment of spastic hip dislocation by proximal femoral resection-interposition arthroplasty (PFRIA) has not been popular because of previous unfavorable experience with Girdlestone-type resections. Since 1979, four severely disabled patients with cerebral palsy having five painful, spastic hip dislocations have undergone PFRIA at the Children's Hospital of Eastern Ontario (Ottawa, Ontario, Canada) by the technique described by Castle and Schneider. The preliminary follow-up shows no significant loss of motion, no bony ankylosis or impingement, no myositis ossificans, and no recurrence of pain. A comfortable sitting status was achieved within 3-6 weeks postoperatively. For a carefully selected group of severely disabled, spastic, nonambulatory patients with painful hip dislocation, we recommend this procedure over more complicated reconstructive procedures or arthrodesis.

Adolescent↗

Intraarticular fractures of the distal humerus in the adult.

Intraarticular fractures of the distal humerus are notoriously difficult to treat. Three basic treatment methods are available: closed reduction, traction, and open treatment. In the past, functional results with all these methods generally have been poor because of disabling limitations of elbow motion. Thirteen adult patients were treated by open reduction and application of medial and lateral buttress plates providing rigid internal fixation and early motion. The patients were evaluated for range of motion, infection, nerve injury, avascular necrosis, myositis ossificans, varus/valgus deformity, pain, instability, weakness, and degenerative changes. Ten of the 13 patients were available for follow-up study for an average of two years. Nine of the ten achieved good or excellent results. Based on these observations, the treatment of choice is internal fixation with dual plates combined with early active postoperative motion.

Adolescent↗

Computerized tomography of pelvic osteomyelitis in patients with spinal cord injuries.

Computerized tomography (CT) was performed in 19 patients with spinal cord injury (SCI) who had large pressure sores and in whom other complications were suspected. CT detected the depth, extent, and degree of undermining of the edges of the pressure sores in 19 of 27 lesions. Conventional radiography detected four cases of pelvic osteomyelitis. CT detected eight additional cases of pelvic osteomyelitis, as well as eight clinically unsuspected peripelvic and intrapelvic abscesses. Technetium-99m bone scanning was not very helpful because of localization in chronic proliferative changes of bone and widespread foci of myositis ossificans, as well as in osteomyelitis. Gallium-67 scanning detected only one of six abscesses. It was not very helpful because of confusion of abscess and osteomyelitis with intense soft tissue swelling and cellulitis, which are often associated with pressure sores in patients with chronic SCI. CT was found to be, by far, the modality of choice for detection of pelvic osteomyelitis and abscess in patients with SCI.

Abscess↗

Tumoral calcinosis in an infant. A case report.

An unusual calcified soft tissue mass in the knee of an 18-month-old black male infant proved to be tumoral calcinosis. A relatively rare disorder of unknown etiology, this is one of the few reported cases of its occurrence in the knee. The diagnosis is one of exclusion. Because of their radiographic similarity, the differential diagnosis includes intracapsular and paraarticular chondroma, traumatic myositis ossificans, and calcinosis circumscripta.

Calcinosis↗

The pelvic digit.

The authors present an illustrative case report of "pelvic digit" and discuss this benign skeletal anomaly. The similarity of this condition to posttraumatic myositis ossificans, avulsion injuries of the pelvis, and osteochondroma is pointed out.

Bone Development↗

Pathogenesis of experimental heterotopic bone formation following temporary forcible exercising of immobilized limbs.

In rabbits, repeated passive forcible exercising of immobilized hip, knee, ankle, or elbow joints produced muscle necrosis within a few days. Within two to five weeks, heterotopic cartilage and bone formation occurred in the soft tissues around the joint and in the area of damaged muscle. The changes were morphologically and radiographically similar to those observed in human myositis ossificans. The incidence of these changes was correlated with the duration of immobilization and the frequency of manipulation. Ossification occurred especially in muscle attachments to bone. Denervation, administration of diazepam, or narcosis during manipulation did not prevent the development of heterotopic bone. Treatment by passive manipulation, immobilization, crushing the muscles, or repeated injections of autogenous blood into the muscles did not induce significant calcification. Heterotopic bone formed as a consequence of repeated forcible distention of previously immobilized soft tissues.

Animals↗

New cytomorphologic methods in the diagnosis of bone tumors: possibilities and limitations.

The value of new morphologic methods in the diagnosis of bone tumors is demonstrated in a number of cases. In round cell malignancies (Ewing's sarcoma, malignant lymphoma, neuroblastoma, and anaplastic plasmacytoma) diagnostic accuracy can be improved by electron microscopic and immunohistochemical techniques. New methods are also of value in differentiating the metastatic carcinoma from malignant bone primaries. Electron microscopy may show epithelial cell features (ie, gland structures, desmosomes, and tonofilaments), while immunohistologic investigation of the cytoskeleton may facilitate differentiation of epithelial cells (positive for prekeratin) from mesenchymal cells (positive for vimentin). In the differential diagnosis of typical bone tumors, however, such as osteosarcoma, chondrosarcoma, and malignant fibrous histiocytoma, the value of enzyme histochemical, electron microscopic, and immunohistochemical methods appears somewhat restricted: alkaline phosphatase activity may be increased in both chondrosarcoma and osteosarcoma; collagen type II, the cartilage-specific collagen, is found not only in chondrosarcoma but in osteosarcoma as well. Moreover, osteosarcomas may contain a considerable number of macrophages and histiocytes, and so this feature is worthless in distinguishing osteosarcoma from malignant fibrous histiocytoma. A new approach for appraising the malignancy of bone tumors may be through flow cytometric investigation of nuclear DNA content. Osteosarcomas reveal DNA aneuploidies in more than 80% of cases, with a large proportion of cells in the S phase. These features may prove valuable for discerning osteosarcoma from myositis ossificans. In contrast to typical giant cell tumor of bone, a rare case of malignant giant cell tumor showed aneuploid cell lines indicating the malignant nature of the tumor.

Bone Neoplasms↗

Solitary osteochondroma of the foot: an in-depth study with case reports.

Osteochondroma represents the most common benign bone tumor and occurs most frequently in the proximal humerus, tibia, and distal femur. The bones of the foot, by comparison, are less commonly involved. The tumor appears to be a developmental defect of bone preformed in cartilage rather than a true neoplasm. However, on rare occasions it may undergo chondrosarcomatous degeneration, thus demonstrating neoplastic behavior. A review of the literature, including clinical features of osteochondroma, radiologic and histologic characteristics, and theories on pathogenesis, is presented. Information concerning principles of surgical treatment, techniques of diagnosis, and facts to aid in the differential diagnosis of osteochondroma is presented also. Finally, a series of case reports is presented to demonstrate the surgical treatment of osteochondroma of the foot. Included are three cases of phalangeal osteochondroma, one of metatarsal osteochondroma, and an unusual report of osteochondroma of the talus. A case report and discussion of a patient with juxtacortical circumscripta myositis ossificans of the foot is also presented to demonstrate how information on lesions included in the differential of osteochondroma can be utilized clinically to make the diagnosis.

Adult↗

Surgical treatment of displaced supracondylar fractures of the humerus in children. Analysis of fifty-two cases followed for five to fifteen years.

Long-term review of fifty-two displaced supracondylar humeral fractures in children treated by open reduction and crossed Kirschner-wire fixation demonstrated functional results similar to those obtained by closed methods, but fewer and milder cases of cubitus varus deformity (only 25 per cent of patients). The deformity appeared to result from faulty reduction with medial angulation of the distal fragment. Surgical treatment of these fractures may offer, as its principal advantages: reduced hospitalization time, fewer sequelae, more stable fixation, and slightly better anatomical results. No infections or other specific complications (such as myositis ossificans or Volkmann's contracture) were encountered.

Adolescent↗

Fascial arthroplasty for elbow ankylosis.

Fifty-one cases of elbow ankylosis treated with fascial arthroplasty were studied. Forty-two cases (85.4%) of elbow ankylosis were due to injuries; chronic dislocation (24), traumatic myositis ossificans (14) and gunshot wounds (4). Eight were due to infection and one to congenital humero-radial synostosis. Seventy-six per cent of all cases had fairly good results and 24% were regarded as failures. The results obtained justify the use of fascial elbow arthroplasty for elbow ankylosis.

Adolescent↗

Mineralization of connective tissue surrounding implanted devices.

Calcification and ossification of soft tissues occurs as a response to a variety of injuries such as atherosclerosis, myositis ossificans, and caseous necrosis. These injuries and others have as a unifying characteristic persistent necrotic tissue elements. Normal tissues may calcify under conditions of hypercalcemia or hyperphosphatemia. The initial mobilization of Ca and P following injury is rapid, as observed in calcergy. The mitochondria of cells, normally a storehouse of Ca, become preferential sites of precipitated Ca when cells are irreversibly injured, and act as foci of progressive calcification. Collagen fibers undergo calcification directly, principally when they are located within devitalized sites such as prosthetic heart valves, and direct calcification of collagen may predominate generally in dystrophic calcification. VArious porous sponges act as foci for calcification and ossification, and the utilization of porous implants may provide for the development of therapeutically useful calcifying and ossifying biomaterials.

Animals↗

Muscle-tendon injuries in young athletes.

The pediatric athlete with open physeal plates is more susceptible to growth plate injuries and avulsion fractures rather than ligament and muscle-tendon injuries that most often occur in adults. In general, the pediatric athlete is able to return to full activity quicker than the adult athlete because of a more rapid healing response. There has been a recent interest in the study of the pathophysiology of muscle-tendon injuries and treatment strategies based on these studies have changed. Laboratory studies have several implications regarding the prevention of muscle-tendon injuries. Clinical studies to confirm their efficacy are needed. Complications of re-injury include more serious injury and conditions such as myositis ossificans. Injury prevention has focused on the use of protective equipment and an emphasis on stretching and strengthening programs.

Adolescent↗

An unexpected, benign cause of increased muscular uptake at bone scintigraphy.

Bone scintigraphy was performed in a healthy 30-year-old man because of post-traumatic heel pain. The scintigraphy displayed a bilateral increased uptake of 99mTc-MDP in the pectoral muscles and triceps brachii. Further extensive investigations including muscle biopsy were normal and excluded diagnoses such as polymyositis, myositis ossificans or amyloidosis. The abnormalities were in fact explained by physical exercise performed a few hours prior to the radionuclide scan. This was confirmed by the absence of these changes on a second bone scan performed 3 months later. This case shows that muscle exercise should be kept in mind as a cause of skeletal muscle uptake of bone-seeking agents, with the view to avoid unnecessary investigations.

Adult↗

Parosteal osteosarcoma.

A case of parosteal osteosarcoma is reported. In spite of the pathognomonic plain radiographic signs of parosteal osteosarcoma, it is very uneasy to differentiate it from myositis ossificans circumscripta in the mature stage. CT and MRI defined the extent of the tumor into the soft tissue, the medullary and cortical invasion and gave more information about the composition of the lesion.

Adult↗

Cat-scratch disease mimicking rhabdomyosarcoma.

A 12-year-old boy who had injured his elbow presented with a lump in the epitrochlear area. Originally thought to be a hematoma, then later myositis ossificans, this mass was actually a lymph node with large, reactive germinal centers. Although stains for acid-fast bacilli, fungal organisms, bacteria, and cat-scratch disease were negative, serological testing for detection of Rochalimaea henselae organisms found evidence of cat-scratch disease. We would like to remind orthopaedic surgeons to consider this diagnosis in evaluating masses of the soft tissues of the extremities.

Cat-Scratch Disease↗

Imaging of soft tissue tumors.

In summary, MR imaging is the preferred modality for the evaluation of a soft tissue mass after plain films have been taken. The radiologic appearance of certain soft tissue tumors or tumorlike processes such as myositis ossificans, benign fatty tumors, intramuscular hemangiomas, pigmented villonodular synovitis, and certain hematomas may be sufficiently unique to allow a strong presumptive radiologic diagnosis. It must be emphasized that MR cannot reliably distinguish between benign and malignant lesions, and when radiologic evaluation is nonspecific, one is ill advised to suggest a lesion is benign or malignant solely on the basis of its MR appearance. CT may be useful in specific instances for the identification of subtle soft tissue mineralization in those patients in whom lesions are not adequately evaluated by radiographs. Ultrasonography may be useful in the assessing of recurrent disease as well as in establishing tumor vascularity.

Diagnosis, Differential↗

[Calcifying tendinitis of the femur--diagnosis and differential diagnosis exemplified by 5 cases].

Five cases of calcifying tendinitis of the femur are presented. Diagnosis were proved histologically or catamnestically. The calcifying tendinitis occurred secondary to localized regressive changes in 3 patients; in 2 cases systemic inflammatory disease had to be assumed. In patients with unclear femoral pain and radiologically visible calcifications, especially at the linea aspera, one should include a calcifying tendinitis in the differential diagnosis besides juxtacortical osteosarcoma and myositis ossificans. This entity can sometimes be a symptom of systemic disease such as psoriasis and palmoplantar pustulosis.

Adult↗

Intense uptake of technetium-99m-MDP in primary breast adenocarcinoma with sarcomatoid metaplasia.

Focal soft-tissue accumulation of bone-seeking radiopharmaceuticals has many causes but is usually less intense than skeletal activity. Extraskeletal new bone formation, as seen in myositis ossificans and extraskeletal osteosarcoma, represents an exception where markedly increased uptake can be seen. Technetium-99m-MDP uptake in primary breast carcinoma has been recently investigated using scintamammographic techniques to differentiate malignant from benign lesions. The mechanism of uptake remains unclear but is likely multifactorial and nonspecific. We present a case of primary breast carcinoma with florid 99mTc-MDP activity relative to normal bone. Tumor histopathology in this patient demonstrates malignant new bone formation as the likely mechanism for the marked radiotracer avidity.

Breast Neoplasms↗