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Sarcoidosis of the head and neck.

Sarcoidosis is a multisystem granulomatous disease of unknown etiology, occasionally presenting with signs or symptoms that occur within the head and neck. The diagnosis may be made by a combination of histological evaluation of involved tissue, the presence of a relative cutaneous anergy, a positive Kveim test, and certain abnormal laboratory or radiographic findings. Although pulmonary sarcoidosis is by far the most common manifestation of the disease, an occasional patient will present with involvement of the nose, tonsils, larynx, or parotid gland. The otolaryngologist should include this entity in his differential diagnosis of lesions which occur in these areas.

Humans↗

Are the oral manifestations associated with HIV infection really relevant to the practising South African dentist? A comparative analysis of oral HIV studies in South Africa.

This comparative analytical review of oral HIV in South Africa, Africa and the West shows that relatively little work has been done on the African continent in this field of study. Direct epidemiological comparisons of these studies with each other are difficult but were made between these regions for overall prevalence values, mode of transmission and individual lesion presentation (candidiasis, oral hairy leukoplakia, periodontal disease, Kaposi's sarcoma, salivary gland disease, oral ulcers and other lesions). Apparent differences exist between the reported prevalence values of oral candidiasis, periodontal disease, Kaposi's sarcoma and tuberculous ulcers, the significance of which is uncertain. There is a need to standardise research methodologies. This would enable appropriate comparisons to be made and a better understanding of the implications of the oral HIV disease process in South Africa and elsewhere on the continent.

AIDS-Related Opportunistic Infections↗

[Study of ganglioside therapy in maxillofacial surgery].

56 patients have been treated with cerebral gangliosides by the Authors. They underwent a maxillo-facial operation due to various pathological reasons (traumas, tumors, malformations). They presented secondary symptoms such as neurological deficits of the V and VII paired cranial nerves. The recovery from neurological sensitive, motor deficit have been positive, and the Authors have been encouraged to the therapeutical use of gangliosides in the mentioned pathology and to a wider experiment of the test product.

Adolescent↗

[Present role of diagnostic imaging in the study of extensive pathology of the parotid gland].

After the introduction in diagnostic imaging of CT and US beside sialography (SG), today it is possible completely evaluate the ductal system as well as the parenchima of the parotid gland. The authors examine the results and limitations of these new imaging modalities, outlining their role in the evaluation of parotid masses. Echography, because of high sensitivity, seems to be the method of choice for the first approach to this pathology, while sialography and CT can be successful in some circumstances: the first allows to easy outline the inflammatory involvement of the gland, while CT seems to be essential for the study of deeply situated tumors and for a complete spatial evaluation.

Diagnosis, Differential↗

Chronic sialadenitis of the submandibular gland. A retrospective study of 108 case.

The main etiologic factor in chronic sialadenitis of the submandibular gland is the salivary calculus. One hundred eight extirpated submandibular glands with the clinical diagnosis of chronic sialadenitis were histologically examined. The intensity of parenchymal destruction was related to the duration of symptoms prior to surgery. With the exception of four cases the glands showed histologically a varying degree of pathologic alterations. In almost one-third of the cases no acinar structures were found. The duration of symptoms ranged from 1 week to 55 years. No statistical evidence of correlation existed between the duration of symptoms and the degree of histological changes.

Adult↗