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Amoebiasis.

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Amebiasis↗

[Localization of Entamoeba histolytica antigens using IgA].

The presence of IgA anti-Entamoeba histolytica antibodies has been demonstrates in intestinal secretions and serum of human amebiasis. We investigated which are the cellular components of trophozoites that react with IgA anti-ameba antibodies from immune serum, colostrum and human milk. The cellular localization of such antigens was accomplished by an indirect immunoperoxidase technique using anti-human IgA (alpha chain specific) labeled with peroxidase, both for light and transmission electron microscopy. Intracellular antigens were localized after permeating the parasites with cold acetone (-10 degrees C) for 3 min. and cryosections of 1 micron thick. The antigens that react with IgA antibodies from immune serum, colostrum and human milk were located in the plasma membrane and the internal portion of some cytoplasmic vesicles. So far, it is unknown what is the biological function of IgA in human amebiasis but in other systems it protects against certain parasites.

Animals↗

Examinations of digestive system parasitoses in people back from the tropics and subtropics.

The paper presents results of epidemiological-clinical studies of digestive system parasitoses in persons (seamen and other professional groups) back from the tropics. The author carried out multidirectional examinations (general medical with rectoscopy, laboratiorial: parasitological, microbiological, mycological and epidemiological) of 3,315 persons. The results were evaluated statistically. He defined the frequency of particular parasite invasion in men in dependence on region of stay, profession, length of service and age, and frequency of occurrence of symptomatic parasitoses as well as clinical picture of particular parasite species invasion. Special attention was paid to amoebiasis which the author separated from the whole material under analysis. The author made a comparison between cases of imported (181) and indigenous (164) amoebiasis as well as amoebiasis found in foreigners coming from tropical countries and staying in Poland (38). On the basis of many years observations of persons cured of amoebiasis he analysed the probability of occurrence of postamoebic syndrome. The material under examinations allowed to recognize the picture of digestive system parasitoses imported to Poland from the tropics.

Amebiasis↗