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[Development of ligament-bone junction in anterior cruciate ligament reconstruction with the scaffold type polyester artificial ligament (Leeds-Keio) in the dog].

The anterior cruciate ligament (ACL) was reconstructed in sixty mongrel dogs with artificial ligament (Leeds-Keio). The tibial ligament-bone junction was completely removed before the reconstruction in order to investigate the remodelling process of the junction. The dogs were divided into five groups. In all of these the artificial ligament was taut when implanted except for one group which had deliberately a slack reconstruction. In three groups the reconstructions included the use of a strip of infrapatellar synovium alone or with a strip of fascia lata within or outside the artificial ligament. After two, four, twelve and twenty-four weeks, the tibial junction was investigated macroscopically, histologically and by means of microangiography. Newly formed fibrocartilage and functionally aligned collagen were observed in the junction 12 weeks after the initial surgery in all groups, but not in the group with a slack reconstruction. From the results of this study, it was concluded that infrapatellar synovial transfer improved tissue induction in the early stages, and further, the additional use of the fascia speeded up the remodelling process.

Animals↗

Macrocyclic polyesters. I. A novel class of 1,3-butandiol derivatives as potential antimicrobial agents.

This paper reports the synthesis of a novel class of macrocyclic tetraesters containing 1,3-butandiol sub-units by reacting the stannolan derivative of the diol with diacyl chloride. The structure of the possible isomers was assigned by spectroscopic data and comparison with samples otherwise prepared. Preliminary screening revealed that these compounds have low antimicrobial activity, although it is higher than that of the starting diol.

Anti-Bacterial Agents↗

[Structural study on the transparency of cross-linked polyester polyurethane].

The polyurethane material with cross-linked structure was synthesized using half pre-polymerization method. IR, UV-Vis, TEM and XRD methods, and physical properties measurements indicate that different moulding temperatures influence the apparent transparence of polyurethane and abrasive performance, and the nature of these changes is related to the conditions of processand chemical reaction which lead to gradual micro-phase separation of the polyurethane molecules with different compositions, resulting in the domain-forming with the size of sub-micro-, micro- and even more than ten micro-meters. Such domains aggregate one another to form particles with different shapes and complicated structures. The increase in the amount and size of these heterogeneous particles, distributed in the medium of transparent polyurethane, is the main cause that brings on an opaque appearance of polyurethane.

English Abstract↗