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A comparison of three methods for inducing labor: oral prostaglandin E2, buccal desaminooxytocin, intravenous oxytocin.

A study of labor induction in 325 patients is reported. Group I (77 patients with Bioshop's scores 0-6) and 2 (69 patients with Bishop's scores 7-12) were given 0.5 mg prostaglandin E2 every half hour (maximum 5 mg per day). Group 3 (87 patients with Bishop's scores 0-6) was givne 50 International units of buccal desaminooxytocin every half hour (maximum 500 International units per day). In Group 4 (92 patients with Bishop's scores 7-12), labor was induced by primary amniotomy and automatic oxytocin infusion by the Cardiff method. In groups 1, 2 and 3, 45 per cent, 74 per cent and 41 per cent delivered within 48 hours, while 100 per cent in group 4 delivered within 24 hours. No differences were found in either the frequency of cesarean section or the incidence of low Apgar scores. A higher, but not statistically significant frequency of vacuum extraction was found in the Cardiff group (25 per cent) than in the tablet-induced groups (15 per cent). There was, however, a significantly higheroccurrence of alterations in fetal heart rate which led to instrumental intervention to hasten delivery in the Cardiff group compared to the tablet-induced patients.

Administration, Oral↗

Effect of mode of delivery in nulliparous women on neonatal intracranial injury.

BACKGROUND: Infants delivered by vacuum extraction or other operative techniques may be more likely to sustain major injuries than those delivered spontaneously, but the extent of the risk is unknown. METHODS: From a California data base, we identified 583,340 live-born singleton infants born to nulliparous women between 1992 and 1994 and weighing between 2500 and 4000 g. One third of the infants were delivered by operative techniques. We evaluated the relation between the mode of delivery and morbidity in the infants. RESULTS: Intracranial hemorrhage occurred in 1 of 860 infants delivered by vacuum extraction, 1 of 664 delivered with the use of forceps, 1 of 907 delivered by cesarean section during labor, 1 of 2750 delivered by cesarean section with no labor, and 1 of 1900 delivered spontaneously. As compared with the infants delivered spontaneously, those delivered by vacuum extraction had a significantly higher rate of subdural or cerebral hemorrhage (odds ratio, 2.7; 95 percent confidence interval, 1.9 to 3.9), as did the infants delivered with the use of forceps (odds ratio, 3.4; 95 percent confidence interval, 1.9 to 5.9) or cesarean section during labor (odds ratio, 2.5; 95 percent confidence interval, 1.8 to 3.4), but the rate of subdural or cerebral hemorrhage associated with vacuum extraction did not differ significantly from that associated with forceps use (odds ratio for the comparison with vacuum extraction, 1.2; 95 percent confidence interval, 0.7 to 2.2) or cesarean section during labor (odds ratio, 0.9; 95 percent confidence interval, 0.6 to 1.4). CONCLUSIONS: The rate of intracranial hemorrhage is higher among infants delivered by vacuum extraction, forceps, or cesarean section during labor than among infants delivered spontaneously, but the rate among infants delivered by cesarean section before labor is not higher, suggesting that the common risk factor for hemorrhage is abnormal labor.

Birth Injuries↗

Pattern of external birth trauma in southwestern Saudi Arabia.

The pattern and associations of 62 instances of external birth trauma (EBT) in 57 of 2222 consecutive hospital-born neonates were studied. Macrosomia and vaginal instrumental or breech delivery were identified as significant risk factors for EBT. In contrast to previous reports, subgaleal hemorrhage (SGH) was the predominant form of trauma (n = 33) and it was associated with vacuum application in 28 of 33 (85%) neonates. Brachial plexus palsy (BPP) (n = 10) occurred with the highest frequency (6.4%) after breech delivery. Fractures were uncommon. Multiple injuries (10 items in 5 babies) were mainly associated with vacuum extraction. The high rate of vacuum extraction (VE) and problems with its use including a high VE failure rate (30/242 = 12.4%) were considered contributory to the unusual pattern of EBT seen in the study. Regular audit of delivery practices, greater care in excluding cephalopelvic disproportion and judicious use of VE are recommended to reduce the morbidity from EBT.

Birth Injuries↗

[The dynamics and trends in surgical delivery at the Maternity Home of the State Institutional Hospital].

The study discusses the frequency of operative obstetric deliveries (cesarean section, forceps extraction and vacuum extraction) over a period of 18 years from 1976 till 1993. A total of 100,545 deliveries with 100,192 livebirths took place during this period with a decrease of the annual number of deliveries in the last years. The frequency of the various kinds of operative deliveries shows different tendencies. The frequency of cesarean section has increased from 4.87 per cent in 1976 to 19.58 per cent in 1993, this increase being particularly marked during the last 6 years. Meanwhile the vaginal operative deliveries have decreased their frequency. The decrease of forceps extraction is from 4.33 to 2.22 per cent (steadily about 2 per cent during the last years). The frequency of vacuum extraction has dropped from 1.89 per cent to 0 by the end of the 1980 and the beginning of the 1990. The tendencies of the development of obstetric operations are analysed as well as their influence on perinatal outcome.

Bulgaria↗

The hazards of vacuum aspiration in late first trimester abortions.

The incidence of somatic complications in connection with legal termination of pregnancy by vacuum aspiration was analysed in 1,123 hospital patients. Special attention was paid to complication rates in relation to gestational age. It was found that the incidence of major uterine haemorrhage increased with gestational period, being unexpectedly high in the 12th week. When anaesthesia was supplemented with halothane there was a significantly higher incidence of uterine haemorrhage that when this anaesthetic was avoided. The results indicate that strict principles for the operation procedure are mandatory to reduce blood loss and other complications. It is suggested that the end of the 12th week should not be considered as a "magic" time limit for vaccum aspiration but that the policy should aim at early intervention, preferably before the end of the 10th week. In the event of late first trimester abortions or "border line" cases it is of advantage to administer prostaglandin extra-amniotically for pre-operative dilatation of the cervix.

Abortion, Induced↗

Mode of delivery in deep transverse arrest.

OBJECTIVES: To determine the trends in the mode of delivery in deep transverse arrest (DTA) over two decades and their impact on maternal morbidity and neonatal outcome. METHODS: Obstetric and neonatal records of women with DTA who delivered at Nehru Hospital, PGIMER, Chandigarh in the years 1970, 1980 and 1990 were analyzed. RESULTS: Although Kielland's forceps was used very frequently in 1970 (44.4%) it had disappeared by 1990 because of increased morbidity associated with it. Instead, use of vacuum extractor and cesarean section has increased over the years. Manual rotation forceps extraction was the most commonly used vaginal method of delivery over two decades (49.5%). Perinatal outcome was better with manual rotation forceps extraction or vacuum extraction as compared to Kielland's forceps. Cesarean section was associated with a high incidence of birth asphyxia (30%). CONCLUSIONS: Manual rotation forceps extraction and vacuum extraction are safe methods of delivery in DTA. Cesarean section as an alternative does not improve the perinatal outcome.

Cesarean Section↗

Rapid evolution of a growing skull fracture after vacuum extraction in case of fetal hydrocephalus.

Vacuum extraction in nonprogressive labor is relatively safe. Only a few major complications have been mentioned. This article describes the rapid development of a growing skull fracture associated with a porencephalic cyst and parenchymal brain damage after a difficult vacuum extraction in a patient with congenital hydrocephalus and a thoracic meningomyelocele. The diagnostic and therapeutic management is discussed.

Abnormalities, Multiple↗

Acceptability of a nonsurgical method to terminate very early pregnancy in comparison to vacuum aspiration.

Seventy-seven patients applying for abortion during early pregnancy consented to be treated by prostaglandin vaginal suppositories or vacuum aspiration by Kahrman catheter in a random design. They also consented to participate in an acceptability study of the two procedures. Attitude and preference measures were obtained by interviewing and rating scales on three occasions: before assignment to abortion procedure, immediately after treatment, and two weeks later. The first 30 patients with complete abortion by either procedure participated in the acceptability study. Both treatments were positively evaluated but perceived to have very different characteristics. The preference for the method used for own treatment increased in both groups. Before treatment 1/3 of the patients in each group had a positive attitude to a self-administered method to induce abortion outside clinics. This proportion increased significantly after treatment but only in the group that received prostaglandin by the vaginal route.

Abortion, Induced↗

Perinatal glucose metabolism as an indicator for stress and hypoxia during different forms of delivery.

In 82 term newborns divided into three groups (spontaneous delivery, caesarean section and vacuum extraction) we investigated umbilical artery pH, artery and vein glucose levels and calculated the veno-arterial difference of glucose. The three groups showed significant differences of artery and vein glucose levels. The highest umbilical artery (UA) and umbilical vein (UV) glucose levels were found after vacuum extractions (n = 13, UA: 98 mg/dl, UV: 104 mg/dl), the lowest levels were present in the group of caesarean section (n = 16, UA: 52 mg/dl, UV: 65 mg/dl). After spontaneous deliveries the intermediate levels were observed (n = 55, UA: 70 mg/dl, UV: 84 mg/dl). The mean of UA-UV-glucose difference was low after vacuum extractions and statistically different from the values after caesarean section and spontaneous deliveries. The mean of UA-pH did not show statistically significant differences in the three groups. The regression analysis between UA-pH and UA-UV-glucose difference revealed a highly significant dependency in the group of caesarean section (p less than 0.01) but no dependency after vacuum extraction. Significant dependency was also found in the group of spontaneous delivery (p less than 0.05).

Analysis of Variance↗

[A comparative study of 2 ways of clinical management in premature rupture of the membranes at term: temporization versus labor induction].

Two defined management approaches, temporization limited to 48 hours and immediate induction of labor, for premature rupture of the membranes at term were compared in a prospective study between January 1 1991 and November 30 1993 in the Maternity Unit of Yaoundé University Hospital. During this period, 268 cases of premature rupture of the membranes were seen among 3252 deliveries, i.e. an incidence of 8.2%. In the temporization group (153 cases), spontaneous onset of labor was effective in 95 patients (62.1%) within 12 hours and in 137 patients (89.5%) within 24 hours after premature rupture of the membranes. Spontaneous deliveries in this temporization group accounted for 129 cases (92.8%). In the induction of labor group, spontaneous delivery occurred in 119 cases (93.2%). There were ten cesareans in the temporization group and eight cesareans and two vacuum cup extractions in the induction group. Short term (24 hours) prophylactic antibiotics were given to 34 patients, i.e. 16 cases in which the duration of rupture of the membranes was more than 24 hours and 18 cases of cesarean section. Maternal infections concerned 18 cases (6.7%) including 12 cases (4.4%) of malaria. Microbiology of vaginal swabs revealed 6 cases of pseudomonas, 4 cases of staphylococcus aureus and 3 of candida albicans. Neonatal infections confirmed by blood culture and assay of C-reactive-protein involved 24 cases (20.3%). There were three fetal deaths, i.e. perinatal mortality of 1.1%. Risk factors, in these three fetal deaths, included postmaturity (1 case).(ABSTRACT TRUNCATED AT 250 WORDS)

Anti-Bacterial Agents↗

Long-term neurological sequelae following vacuum extractor delivery.

Two hundred and ninety-five children delivered by vacuum extractor (VE) 10 years ago were studied to determine if they had an increased incidence of neurological abnormality; 302 children delivered spontaneously in the same hospital looked after by the same doctors in the same year matched for maternal age, gestational age and birthweight were used as controls. Fine- and gross-motor control, perceptual integration and behavioural maturity were screened by 4 tasks selected from the Quick Neurological Screening Test. Intelligence assessment was based on scholastic performance, speech ability and ability of self-care as commented by teachers and parents. Similar scorings were found between the 2 groups. Mental subnormality or severe neurological abnormality was found in 3 children delivered by VE and in 3 children delivered spontaneously and there was no evidence that it was birth-related.

Child↗

Acid-base evaluation of umbilical cord blood: relation to delivery mode and Apgar scores.

Acid-base status of umbilical artery and vein blood was measured immediately after delivery in 300 cases. A slight acidosis of mixed respiratory/metabolic type was found in newborns delivered following a second stage of 10-30 min duration. After a second stage of more than 30 min the metabolic contribution to the acidosis was predominating. With Apgar scores lower than 10 the pH was found to decrease and carbon dioxide tension to increase. Induction or augmentation of labor by oxytocin did not influence the acid-base status of umbilical cord blood. Delivery by vacuum extraction or low forceps resulted in lower pH and higher carbon dioxide tension in umbilical cord blood, but the changes were associated with the indication for instrumental delivery and not with mode of delivery. A large arterio-venous difference between the acid-base parameters was usually connected to vigorous newborns and a small difference to depressed infants. The carbon dioxide tension was usually increased in newborns with decreased pH, and a close correlation between these parameter was found. No case of acidosis (pH below 7.15) was found in this population at carbon dioxide tensions below 7.2 kPa; at higher Pco2 values only 25% of the newborns were acidotic. A Pco2 level of 7.7 kPa might be used at transcutaneous carbon dioxide monitoring during labor, although the sensitivity and specificity of this parameter will have to be decided in a prospective study.

Acid-Base Equilibrium↗

[Management of labor after previous cesarean section].

Knowledge of the recent literature and evaluation of 210 deliveries in our own hospital are intended to help to provide an assessment of delivery management after prior cesarean section. In 56.6% of the cases, resection was chosen as the mode of delivery after cesarean section. The primary resection rate was 29.5% and the secondary rate 27.1%. Protracted labour is the main indication (around 60%) for secondary resection. Secondary resection is subject of a high maternal morbidity. The overall rate of uterine ruptures in the patients (1.4%) corresponds to the international level. 43.4% of the patients were delivered vaginally, 15.4% of these by vacuum extraction. An individualized procedure is necessary and to be aimed for in view of the problems discussed. The conclusions emphasize the main points of the procedure in management and delivery of pregnant women with a cesarean section in the case history.

Cesarean Section↗

Operative vaginal delivery and neonatal and infant adverse outcomes: population based retrospective analysis.

OBJECTIVE: To compare the risk of neonatal and infant adverse outcomes between vacuum and forceps assisted deliveries. DESIGN: Population based study. SETTING: US linked natality and mortality birth cohort file and the New Jersey linked natality, mortality, and hospital discharge summary birth cohort file. PARTICIPANTS: Singleton live births in the United States (n = 11 639 388) and New Jersey (n = 375 351). MAIN OUTCOME MEASURES: Neonatal morbidity and mortality. RESULTS: Neonatal mortality was comparable between vacuum and forceps deliveries in US births (odds ratio 0.94, 95% confidence interval 0.79 to 1.12). Vacuum delivery was associated with a lower risk of birth injuries (0.69, 0.66 to 0.72), neonatal seizures (0.78, 0.68 to 0.90), and need for assisted ventilation (< 30 minutes 0.94, 0.92 to 0.97; > or = 30 minutes 0.92, 0.88 to 0.98). Among births in New Jersey, vacuum extraction was more likely than forceps to be complicated by postpartum haemorrhage (1.22, 1.07 to 1.39) and shoulder dystocia (2.00, 1.62 to 2.48). The risks of intracranial haemorrhage, difficulty with feeding, and retinal haemorrhage were comparable between both modes of delivery. The sequential use of vacuum and forceps was associated with an increased risk of need for mechanical ventilation in the infant and third and fourth degree perineal tears. CONCLUSION: Although vacuum extraction does have risks, it remains a safe alternative to forceps delivery.

Cohort Studies↗

Maternal and neonatal C-reactive protein after interventions during delivery.

To evaluate the effects of interventions during delivery on the maternal and neonatal C-reactive protein (CRP) we prospectively measured CRP by immunoturbidometry in 238 mother-infant pairs (179 normal vaginal deliveries, 36 cesarean sections and 23 vacuum extractions) at 24 and 72 hours after delivery. We additionally measured CRP in peripheral maternal and neonatal blood immediately after birth in 29 uncomplicated vaginal deliveries. CRP values in the mothers and their offspring were low at birth, but rose significantly during the first day after vaginal delivery. Cesarean section induced a pronounced elevation of maternal CRP, but had no effect on neonatal values. Delivery by vacuum extraction produced a transient elevation of both maternal and neonatal CRP at 24 hours after birth. Neonatal CRP values were not associated with presence or size of superficial birth tissue trauma evaluated simultaneously with blood sampling. Increased CRP release in mothers and their infants after interventions during delivery may be associated with varying degrees of tissue trauma and can complicate assessment of the presence of infection.

Birth Injuries↗

[High vacuum extraction: justifiably obsolete in view of the risks to the infant].

The author was asked to provide an expert assessment of the case histories of 28 patients delivered by vacuum extraction. At the start of the extraction the foetal head level was at station 0 or above in 25 of the patients. In 12 cases the duration of extraction exceeded 14 min and in 7 of the cases it exceeded 19 minutes with a maximum of 45 minutes. Nine of the infants died, 11 suffered cerebral damage, 4 had brachial plexus injury and 1 had both cerebral damage and plexus injury. In 17 cases a causal relation between the unfavourable outcome and the vacuum extraction seemed plausible. During the past 40 years several studies of patients who have undergone high pelvic vacuum extractions have been published; cerebral damage of the infants often occurred. The risk of shoulder dystocia resulting in brachial plexus injury is considerably increased in case of a large infant and mid pelvic or high pelvic delivery. In the paediatric literature a number of authors describe cerebral lesions caused by high pelvic vacuum extraction. High pelvic vacuum extraction is still occasionally practiced in the Netherlands; it is a hazardous technique and should be replaced by caesarean section.

Adult↗