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Results for “Periapical Abscess”

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At least 973 records · Page 54Linked to original sources
PubMed1991

[The clinical efficacy of roxithromycin in patients with acute odontogenic infections].

The clinical efficacy of a macrolide antibiotic, roxithromycin, was evaluated in 24 patients affected by acute odontogenic infections. Patients were treated with a first dose of 300 mg p.o. which was followed by 150 mg p.o. 12-hourly for the following two days. Total responses were evaluated by an arbitrary scale. The results showed that an excellent and good response was obtained in 99.96% of treated patients. On the basis of clinically compared data and the drug safety it may be concluded that roxithromycin can be successfully used in the treatment of odontogenic infections.

Acute Disease↗
PubMed1990

Attainment of hermetic seal with decalcified allogenic bone matrix grafts--surgical vs. conservative approach.

Twenty four non vital upper anterior teeth from twelve healthy patients, between the ages of 18-30 years, having definite radiolucent areas at the periapex, were taken for this study. A comparison was made between the surgical and conservative approach, using decalcified allogenic bone matrix (DABM) grafts to achieve a physiologic seal at the root apex. The period of observation were 60 days, 120 days and 180 days. The clinical and radiological finding of this study strongly support the observation that DABM accelerates osteogenesis and cementogenesis which seal the root apex through a physiological process. The process of healing was quicker when the surgical approach was used. However a longer period of observation and histological study is required before any conclusion can be drawn, as regard the choice of a surgical or conservative approach.

Adult↗
PubMed1990

[Pustular arthro-osteitis. Pustulosis palmaris et plantaris with arthritis of the sternoclavicular joint].

A 26-year-old female patient presented with pustulosis palmaris et plantaris simultaneously with arthritis of the sternoclavicular joint. This association is described as an entity and is called pustulotic arthroosteitis in the Japanese literature, as well as in publications from Scandinavia. To our knowledge, this is the first observation in the Federal Republic of Germany.

Adult↗
PubMedDate not supplied

Why teeth associated with inflammatory periapical lesions can have a vital response.

It is a general conception that teeth having an inflammatory periapical lesion are nonvital and the associated periapical lesions are not innervated. However, structurally intact and functioning nerve fibers have been shown to be present in the periapical lesion and/or the associated pulp. Therefore, when a patient presents with an endodontically involved tooth associated with a periapical lesion and experiences pain during canal instrumentation, the need for local anesthesia is apparent.

Dental Pulp↗
PubMed1989

Ludwig's angina--a case report.

Ludwig's angina is a potentially lethal oro-facial cellulitis due to oro-dental infection. The aetiology and management of a case of Ludwig's angina are briefly discussed.

Adult↗
PubMed1989

Medial mental sinus.

Lighting is an important tool of the photographer, since it can be used to create shadows to highlight the condition under study. For photographs such as the one shown, oblique lighting is essential.

Dental Fistula↗
PubMed1989

[Bacteriological and immunological studies on the mechanism of development of periapical lesion. Immunobiological activities and localization in periapical lesion of the cellular components from Bacteroides buccae].

It has been strongly suggested that the periapical lesion develop as a result of immunopathological response to continuous antigenic stimulation. Bacteria from root canal systems might be most important pathogenesis capable of inducing immunological reactions in periapical tissue. The purpose of this study, therefore, was clarify the immunological potentials of Bacteroides buccae (B. buccae) which was frequently isolated from root canals with chronic periapical lesion. Biological activities of B. buccae cellular components, such as lipopolysaccharides (LPS) and cellular protein were investigated on the enhancement of monocytes migration induction of interleukin 1 (IL-1) production, mitogenicity and polyclonal B cell activation. The localization of immunocompetent cells and B. buccae in human chronic periapical lesions were examined by biotin-avidin-horseradish peroxidase method, and peroxidase antiperoxidase methods using monoclonal antibodies. Following results were obtained. 1. On the lymulus lysafe clotting activity and Shwarzman activity of B. buccae LPS were about half of Salmonella typhimurium (S. typhimurium). 2. Both LPS and 38K protein preparations from B. buccae enhanced the activity of human peripheral monocytes migration and induced IL-1 production. 3. It was found that mitogenicity of LPS from B. buccae on splenocytes of BALB/c and BALB/c nu/nu mice was weaker than that of 38K protein, however mitogenicity on thymocytes were not shown in both preparations. 4. The polyclonal B cell activation on splenocytes of BALB/c nu/nu mice by B. buccae were remarkably induced by 38K protein, but LPS showed less activity elicit than 38K protein. 5. It might be suggested that the both LPS and 38K protein of B. buccae may depend on the activities of macrophage and lymphocytes. 6. Antigenic substance of B. buccae were found most commonly engulfed materials within macrophage and intercellular space in connective tissue. 7. Dense accumulation of T and B lymphocytes were observed gathering around the phagocytic macrophage (foam cell), the number of B lymphocytes around the macrophage was greater than that of T lymphocytes. 8. These findings indicated that both LPS and 38K protein from B. buccae have a wide regulation function of immunobiologic responses. Therefore, it was suggested that both LPS and 38K protein from B. buccae may play significant roles in the pathogenesis of periapical lesion.

Bacteroides↗
PubMed1989

[The roles of macrophage on the mechanism of development of periapical lesion. The response of macrophage stimulated with bacteria isolated from infected root canals].

It has been proposed that bacteria in infected root canals are most important agents to pathogenesis of the periapical lesion. The aim of the present study was to examine the roles of macrophage on the mechanism of development of periapical lesion. Therefore the influences of bacteria isolated from infected root canals to macrophage functions and the effects of products from macrophage stimulated with bacterial components to periodontal tissue were investigated. In this study, sonic extracts prepared from Bacteroides buccae predominantly isolated from root canals were tested for its capacity of induction of chemotaxis and production of prostaglandin E2 and collagenase from human peripheral monocyte. Furthermore prostaglandin E2, collagenase production and alkaline phosphatase activity of fibroblasts from human periodontal ligament (HPLF), pulp (HPF) and gingiva (Gin 1) stimulated with macrophage conditioned medium (MCM) stimulated with B. buccae sonic extracts were examined. The results obtained were as follows. The sonic extract of B. buccae showed capacity to induce macrophage chemotaxis directly and by activation of serum complement, and the serum activated with sonic extract of B. buccae was more active than the serum activated with LPS of Salmonella typhimurium. Prostaglandin E2 production of macrophage was increased when the cells were stimulated by sonic extracts of B. buccae, but collagenase activity. toas not increased. MCM stimulated with sonic extracts of B. buccae fot 48 hours strongly induced PGE2 and collagenase production from HPLF and HPF, at the same time sonic extract showed the similar capacity of induction of the PGE2 production of MCM. But, HPF stimulated with sonic extract showed the low activity of induction of the PGE2 production. On the other hand, Gin 1 cell produced a few amount of the PGE2 when it was stimulated with MCM, but not produced collagenase. Alkaline phosphatase activity of HPLF and HPF had been inhibited by addition of MCM stimulated with B. buccae sonic extract.

Macrophage Activation↗
PubMedDate not supplied

[Radiographic and histological study of a case of apexification in a human molar].

A case of apexification in a lower right second molar is described. Radiographs demonstrate apical closure with a different morphological pattern from that of the lower left second molar. Following extraction, after 15 months, serial histologic sections show calcified tissue obturating the apical foramen, well adapted to the initial dentin and cementum walls. Inside some small areas containing connective tissue with capillaries can be observed. The histologic and radiographic observations indicate that apical closure occurs as a result of differentiation of periodontal apical cells.

Adolescent↗