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At least 1,009 records · Page 56Linked to original sources
PubMed1995

Fat, carbohydrate, and the regulation of energy intake.

High-fat foods are readily overeaten. This could be because fat increases the palatability and energy density of foods or because fat has a low satiety value compared with carbohydrate. In several studies examining the effects of preloads that varied in fat and carbohydrate content on subsequent food intake, there was little difference in the effects of fat and carbohydrate on satiety. A dose-response preloading paradigm gives the most sensitive index of satiety. In one such test it was found that the effects of yogurts varying in fat or carbohydrate content did not differ in normal-weight, unrestrained men. However, in obese individuals or those concerned with body weight, fat in the yogurts was less effective in reducing subsequent food intake than carbohydrate. More studies are required to determine whether this small, but significant, insensitivity to energy from fat affects the regulation of food intake and body weight.

Body Weight↗
PubMed1988

Role of acetone, dietary fat and total energy intake in induction of hepatic microsomal ethanol oxidizing system.

Chronic ethanol consumption results in the induction of a specific hepatic cytochrome P-450 (P450IIE1). However, since compounds other than ethanol (i.e., acetone) can also serve as P450IIE1 inducers, and since ethanol given with a normal fat-containing (35% of energy) diet is associated with acetonemia, hepatic steatosis and decreased body weight gain, the question has been raised whether induction is mediated specifically by ethanol or whether it might represent a nonspecific response to these other factors. This was investigated by varying both the mode of ethanol administration and the composition of the diet. By administering ethanol in the drinking water, or as part of a low-fat (5% of energy) liquid diet, a significant induction of P450IIE1 and of the activities of the microsomal ethanol oxidizing system and p-nitrophenol hydroxylase was demonstrated in the absence of any significant increase in blood acetone with minimal increase in liver total lipids. Induction of P450IIE1 was comparable with the low or normal fat-containing diets, but MEOS activity rose more with the latter, possibly reflecting a potentiating effect of dietary fat on ethanol oxidation by P-450 enzymes other than P450IIE1. When the lack of weight gain of the alcohol fed animals was mimicked in controls by decreasing the amount of diet ingested, no induction was observed. Varying the pattern of liquid diet feeding had no demonstrable differential effect. Thus, the induction of P450IIE1 after chronic ethanol consumption can be attributed to ethanol itself, but dietary fat can potentiate the induction of the microsomal ethanol oxidizing system and of p-nitrophenol hydroxylase.

Acetone↗
PubMed2000

Dietary carbohydrate source and energy intake influence the expression of pancreatic alpha-amylase in lambs.

In ruminants, pancreatic alpha-amylase is the primary enzyme responsible for the initial hydrolysis of alpha-linked glucose in the small intestinal lumen. The objective of this experiment was to examine the effects of altered dietary starch and energy supply on the expression of pancreatic alpha-amylase mRNA, protein and activity in lambs. Wether lambs (n = 24; 28 +/- 0.5 kg body weight) were fed low or high starch diets at 1.2 or 1.8 x net energy of maintenance for at least 28 d before tissue collection. Lambs fed the high energy/high starch diet tended to have more pancreatic alpha-amylase protein (54.5 kDa; P: = 0.08) and had greater activity (P: = 0.03), but alpha-amylase mRNA (1.6 kb) tended to be lower (P: = 0.17). Additionally, rumen fluid total short-chain fatty acid concentration was greater (P: = 0.04) and plasma glucose concentration tended to be greater (P: = 0.07) in lambs fed the high energy/high starch diet. However, pancreatic trypsinogen protein (25. 5 kDa) and jejunal maltase activity were not influenced by dietary treatment, suggesting that different regulatory systems are involved in regulating the tissue protein or activity levels of these two enzymes compared with alpha-amylase. These data suggest that dietary regulation of pancreatic alpha-amylase expression in ruminants is complex and probably regulated by transcriptional and post-transcriptional events.

Animals↗
PubMed2004

Renal function in Palestine sunbirds: elimination of excess water does not constrain energy intake.

Although the renal responses of birds to dehydration have received significant attention, the consequences of ingesting and processing large quantities of water have been less studied. Nectar-feeding birds must often deal with exceptionally high water intake rates in order to meet their high mass-specific energy demands. Birds that ingest large volumes of water may either eliminate excess water in the kidney or regulate the volume of water absorbed in the gastrointestinal tract. Because water absorption in the gastrointestinal tract of Palestine sunbirds (Nectarinia osea) decreases with increasing water ingestion rate, we predicted that glomerular filtration rate (GFR) in these birds would not be unusually high in spite of large ingested water loads. When feeding on dilute sucrose solutions, sunbirds ingested between 4 and 6 times their body mass in nectar per day, yet they were able to compensate for varying nectar energy density and increased thermoregulatory energy demands with no apparent difficulty. GFR was lower than predicted (1976.22+/-91.95 microl h(-1)), and was not exceptionally sensitive to water loading. Plasma glucose concentrations were high, and varied 1.8-fold between fasted (16.08+/- 0.75 mmol l(-1)) and fed (28.18+/-0.68 mmol l(-1)) sunbirds, but because GFR was low, glucose filtered load also remained relatively low. Essentially the entire glucose filtered load (98%) was recovered by the kidney. Renal fractional water reabsorption (FWR) decreased from 0.98 to 0.64 with increasing water intake. The ability of Palestine sunbirds to reduce the absorption of ingested water in the gastrointestinal tract may resolve the potential conflict between filtering a large excess of absorbed water in the kidney and simultaneously retaining filtered metabolites.

Analysis of Variance↗
PubMed1990

Regulation of bovine adipose tissue metabolism during lactation. 6. Cellularity and hormone-sensitive lipase activity as affected by genetic merit and energy intake.

Subcutaneous adipose tissue cell size and density and hormone-sensitive lipase activity were determined during late pregnancy and first lactation in Holstein heifers. Animals were daughters of bulls with either +791 (high line) or +390 (low line) kg Predicted Difference (1974 base) for milk. Each line consumed either a 71%: 29% (high energy) or a 36%:63% (low energy) barley concentrate and alfalfa hay diet from 0 to 140 d lactation. Heifers fed the low energy ration ate 33% less NE1 and produced 20% less milk with 52.7% greater milk fat percentage during 28 to 140 d of lactation than heifers fed the high energy ration. Prepartum, animals of the high line had similar adipocyte volume and density to low line animals. However, during early lactation, high line animals had a greater decrease in volume and a larger increase in density than low line animals. There was a delayed recovery of volume in high line, compared with low line animals in late lactation. Adipocyte volume also was decreased by dietary energy restriction. Hormone-sensitive lipase activity was similar in both genetic lines prepartum and increased in all groups at 60 d postpartum. Animals of high line or fed low energy rations had increased activity per gram during early, but not later, lactation. Activity per cell and per milligram cytoplasm protein increased in all groups in early lactation and were highest in high line animals fed the low energy ration.

Adipose Tissue↗
PubMed1998

Underreporting of energy intake, socioeconomic status, and expression of nutrient intake.

The relationship between socioeconomic status and nutrient intake was examined in a recent study. The investigators used three different expressions of nutrient intake in an attempt to overcome the confounding effect of underreporting on interpretation of dietary intake data. Biologic validation attempts were inconclusive as to which expression yielded the most accurate results.

Adult↗
PubMed1991

Energy intake restriction and oxidant defense.

Caloric restriction alters the expression of genes in rat liver that code for oxidant defense enzymes. Dietary restriction also reduces ethane production, an index of in vivo lipid peroxidation.

Animals↗
PubMed1991

Energy intake profile in the triathlon competition by means of cluster analysis.

The subjects were 18 male triathletes competing in the 4th Kaike Triathlon held at Tottori in 1984. Answers to a questionnaire on dietary and water intake before and during the competition were analysed. Cluster analysis using the average distance method was applied to 21 variables relating to order, age, stature, body weight, total calorie intake and each nutrient element ingested during three periods: after swimming, during cycling and during the marathon. The arrival order was clustered with stature and weight, and its similarity showed 69.7 when the first cluster formed. Age along with carbohydrate, protein or water intake during the marathon formed secondary clusters with order, stature, and weight (similarity: 60.0). In the upper place group, breakfast calories occupied the largest portion of 26.1% and the smallest portion of 17.2% during the marathon running. Furthermore the group ingested more energy than the other groups during cycling.

Adult↗
PubMed1993

Effect of cassava bread supplementation on energy intake of rats.

The effect of supplementing semi-purified diet of rats with milled cassava bread was investigated. Total food intake and weight gain were measured in ad libitum and pair fed animals. Plasma triglyceride levels were determined at the beginning and end of the experimental period. Cassava bread supplementation did not increase total food intake of the animals therefore resulted in a lower food efficiency ratio (FER) of the diet when animals were fed ad libitum. When the animals were pair fed, FER was similar for both diets suggesting that cassava supplementation does not increase significantly the energy content of the diet. Addition of milled cassava bread to the diet did not modify plasma lipid levels. This results support that cassava starch is partially available to the rats. Clinical use of cassava bread is suggested for diabetic and obese patients.

Animal Feed↗
PubMed1999

Sensory responses to fat are not affected by varying dietary energy intake from fat and saturated fat over ranges common in the American diet.

OBJECTIVE: To examine the effects of manipulating dietary fat in foods on sensitivity and hedonic response to fat in selected foods. DESIGN: Twenty subjects were randomly assigned to a sequence of three 8-week experimental diets (average American diet, step 1 diet, low-saturated-fat diet) that varied in energy from fat (37%, 30%, and 26%, respectively) and saturated fat (17%, 10%, and 6%, respectively). Subjects participated in sensory tests designed to assess their sensitivity to and liking for fat in several foods, before the study (baseline), after consumption of each diet, and after the study (washout). SUBJECTS/SETTING: Subjects were participants in the Dietary Effects on Lipoprotein and Thrombogenic Activity (DELTA) study. RESULTS: No significant differences were found among diets for difference thresholds (i.e., just noticeable differences) for fat in milk and pudding, ad libitum mixing of low- and high-fat samples of milk and soup, and hedonic scaling of fat concentrations in milk and muffins and of cheese, mayonnaise, hot dog, and pastry samples. APPLICATIONS/CONCLUSIONS: Within the dietary fat ranges and for the fat stimuli tested in this study, dietary fat as percentage of energy from fat and saturated fat was not a significant determinant of sensitivity to and/or liking for fat. Sensory factors should not be a barrier to the implementation of low-fat diets such as the step 1 and low-saturated-fat diets.

Adult↗