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Replantation of an autoclaved autogenous segment of bone for treatment of chondrosarcoma. Long-term follow up.

Seven patients who had a low-grade chondrosarcoma of the proximal part of the humerus or femur were treated by resection, autoclaving of the excised segment, and reinsertion of that segment with supplementary fresh autogenous grafts. The length of follow-up ranged from fourteen to twenty-four years, and sequential roentgenograms were made during the follow-up period. A biopsy of the autoclaved segments was done in one patient eleven years after the operation, and examination of the specimen showed predominantly live bone; there were very few spicules of dead bone. Although the principal roentgenographic changes were demonstrated by the end of the first year, serial roentgenograms showed a continuing process of remodeling for two decades. No secondary procedures were required for treatment of fracture, resorption, infection, or loss of function.

Adult↗

Orthopaedic management of bony metastases of renal cancer.

Pain and loss of function of the skeleton are the main symptoms of patients with bony metastases of renal cancer. Experience with 57 patients (40 of them had 52 operations) shows the surgical possibilities for early restoration of function and pain relief. Metastases were mainly localized in the femur, vertebral column, and humerus. Surgical management after nephrectomy consisted either in curettage and stabilization with plates and bone cement in case of multiple metastases or in resection and endoprosthetic treatment for solitary lesions. Thus the quality of life could be improved in every case. Survival time and primary diagnosis of hypernephroma prior to the detection of bony metastases are closely related.

Adult↗

[Surgical therapy of pelvic tumors].

Results in 72 patients with primary tumors of the pelvis and in 140 patients with metastases are reported. Classification, localization, type of resection and reconstruction including bone grafts, osteosynthesis and internal hemipelvectomy are described. In benign and low grade malignant bone tumors continuity resections and pelvic reconstructions give good oncological and functional results. In high grade malignant bone tumors and soft tissue sarcomas the 5-years-survival rate is only 37% respectively 19%. Metastases of the pelvis and proximal femur are treated by combinations of metal implants and bone cement as well as by different types of total hip prostheses.

Adult↗

Chondroblastoma. A review of seventy cases.

We reviewed the cases of seventy patients with chondroblastoma who were treated at the Istituto Ortopedico Rizzoli between 1949 and 1983 and found that the proximal end of the humerus was the most common location (eighteen), with the proximal end of the femur (fifteen), distal end of the femur (fifteen), and proximal end of the tibia (twelve) being the other frequently involved sites. Sixty-three of the patients were between eleven and thirty years old. Fifty-eight patients sought medical attention because of an aching pain, usually referred to the adjacent joint. Fifty patients were followed for two years or longer after treatment. Seven patients had a local recurrence: four were successfully treated with a repeat curettage and one, by two subsequent marginal excisions; one was advised to have a repeat curettage; and the seventh was advised to have a resection and arthrodesis of the knee. The final functional results were considered to be excellent in forty-seven of the fifty patients who were followed for two years or more.

Adolescent↗

Bone scintigraphy as a guide to the diagnosis of osteoid osteoma.

This report describes one case in which bone scintigraphy was helpful in establishing the diagnosis of osteoid osteoma and presents three other cases in which increased accumulation of 99mmTc-EHDP was found at the side of the osteoid osteoma. The study contributes to the observation by others that the osteoid osteoma occurs as a scintigraphic 'hotspot'. It is concluded that the diagnostic delay of the osteoid osteoma can be shortened when bone scintigraphy is performed more often and at an earlier stage in patients with unexplained bone pain or with a clinical history that leads to the suspicion of the presence of an osteoid osteoma.

Adolescent↗