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PubMed1969

Osteosarcoma.

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Adolescent↗
PubMed1983

Resection and reconstruction of the distal end of the femur or proximal end of the tibia after radical excision of diaphyseal and epiphyseal segments.

The authors describe a technique of bone reconstruction after radical resection of bone segments from the distal end of the femur or proximal end of the tibia. This involves the insertion of an intramedullary nail of predetermined length which is fixed to the bone by screws applied at the proximal and distal ends of the nail. An aiming device is used which permits the screws to be applied by a closed procedure. The reconstruction is effected by using the diaphysis of the contralateral fibula, which is divided longitudinally into two halves. These are then applied laterally and medially to the endomedullary nail at the site of the resected area. Grafts of cortico-spongy bone taken from the iliac crests are inserted between the two fibular hemidiaphyses. The authors give a detailed description of the operation and report the clinical results obtained in eleven cases and the complications observed.

Adolescent↗
PubMed1983

[Preservation of the affected limbs in the treatment of osteosarcoma in children].

The pre-operative radiotherapy and systemic chemotherapy is effective in reducing the size of tumor and making the tumor resectable. The results achieved with systemic chemotherapy are ultimately reflected in improved survival. Moreover, limb-saving procedure in the treatment of osteosarcoma has become possible with rationality in carefully selected patients. Sixty-seven patients with osteosarcoma within a range of 5 to 27 years of age were treated at Chiba Cancer Center Hospital in the recent 12 year-duration. Seventeen of 67 patients underwent en bloc resection for osteosarcoma of the femur, (12 patients) and the tibia (5 patients). No patients had evidence of local recurrence of the tumor and overall 15 patients are alive without distant metastasis after 9 to 120 months follow-up. Based on the effective chemotherapy schedule, the limb salvation in the treatment of osteosarcoma is most desirable if it is indicated without risk of decreased radicality of the treatment.

Adolescent↗