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Fatal rhinocerebral mucormycosis and diabetic ketoacidosis.

The typical features of a fulminating rhinocerebral infection by the fungus Rhizopus in a patient with diabetic ketoacidosis are described. The clinical presentation was characterized by an infection of the face, followed by rapid bilateral visual loss and massive cerebral infarction due to extensive vascular involvement. Early diagnosis is a prerequisite for successful treatment, which consists of control of the underlying disease, surgical debridement and systemic antifungal therapy.

Diabetic Ketoacidosis↗

[A case of pulmonary mucormycosis accompanied by lymphocytic leukemia successfully treated by pulmonary lobectomy].

A 51 years old man with acute lymphocytic leukemia who was treated with antileukemic chemotherapy, developed sepsis and pneumonia. Secondary infection with Mucor intervened with abscess formation cured by lobectomy. The patient is doing well without evidence of recurrence, and treated successfully with anti-leukemic chemotherapy. Surgical treatment offers the last chance of survival in similar cases.

Humans↗

Mucormycosis.

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Humans↗

Ocular sporotrichosis mimicking mucormycosis in a diabetic.

Primary sporotrichosis of the eye is very rare; most infections are limited to the conjunctiva or adnexa. We report a case of Sporothrix endophthalmitis associated with necrotizing ethmoid sinusitis developing in a young diabetic man with ketoacidosis. The infection clinically resembled rhino-ophthalmic mycormycosis. Cure followed evisceration and an abbreviated course (215 mg) of amphotericin B. Sporothrix must now be regarded as another fungal agent capable of causing primary rhino-ophthalmic infection similar to Mucor.

Adult↗

[Generalized mucormycosis. Apropos of a case caused by Absidia corymbifera].

This is the case of a woman, 49 year old, suffering from acute lymphoblastic common leukemia, who died from respiratory and cardiac insufficiency 47 days after the onset of aplasia. Autopsy revealed cardiac and cerebral dissemination of pulmonary mycosis. Absidia corymbifera (Mucoraceae, Phycomycete) was shown by culture to be the pathogen involved.

Female↗