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PubMed1979

Specificity in response of vaccinated swine and mice to challenge exposure with strains of Erysipelothrix rhusiopathiae of various serotypes.

Swine and mice were vaccinated with standard erysipelas adsorbate bacterins made from Erysipelothrix rhusiopathiae of serotype 2 and were subsequently exposed to pathogenic strains of E rhusiopathiae, serotypes 1, 2, 4, 9, 10, and 11. Response to challenge of immunity in swine was determined by presence of urticarial lesions at the sites of intradermal injection of culture; response in mice was determined by the quantal (live-dead) method. After vaccination with standard bacterins, swine and mice were significantly more susceptible (P less than of equal to 0.01) to infection with strains of serotypes 9 and 10 than with strains of serotypes 1, 2, 4, or 11. An adsorbate bacterin made from the challenge strain of serotype 10 induced specific immunity to homologous challenge exposure in swine but not in mice. Bacterins made from the other challenge strains induced little or no immunity.

Animals↗
PubMed2004

[How I explore ... an enlarged red leg].

A consultation motivated by an enlarged red leg is a common situation. The causes are multiple and the diagnosis primarily relies on case history and physical examination distinguishing inflammatory red legs from erythemato-violaceous presentations. Additional diagnostic search cannot be described as a single standardized procedure. Each disease calls for specific and different paraclinical investigations. The most frequent cause is erysipelas or a thrombophlebitis. Some vascular malformations and some functional circulatory disturbances are also possible, as well as sequelae of panniculitis or borreliosis.

Erysipelas↗
PubMedDate not supplied

[Epidemiologic aspects of group A betahemolytic streptococcus infections in Galaţi County between 1990 and 2000].

The infections caused by group A betahemolytic streptococcus represent a major problem of community health, worldwide and in Romania, too. Between 1990-2000, in the Galati County, scarlet fever registered values of morbidity with a yearly variability between 8.2 and 54.1 cases/100,000 inhabitants. Angina, although underrated, reached values of 30-80%ooo, followed by erysipelas with an incidence of 80-100%ooo. The socio-economical impact was partially highlighted by assessing the dynamics of hospitalizations which registered values from 363.86 to 527.14%ooo inhabitants. To the previous, the costs of bacteriological investigations were added. For example, 60-80% of cases of angina were positive.

Adolescent↗
PubMed1990

[An assessment of body sensitization by the change in the density of the peripheral blood neutrophils].

A simple method for the assessment of the body sensitization has been developed, with peripheral blood neutrophils acting as the test system. The method consists in scintillation of the neutrophil count among the cells of the interphase ring obtained by centrifugation of 1:1 diluted peripheral blood in verografin density gradient, 1.077 g/cm3, after blood incubation with the tested allergen. Increase of the count of the neutrophils among other interphase cells by 20% or more after interaction with the allergen indicates a sensitization to this allergen. The accuracy and specificity of the method have been demonstrated in the examinations of patients with pollenosis and erysipelas.

Allergens↗
PubMed1991

[The peripheral hemodynamics in the inter-relapse period in erysipelatous inflammation of the lower extremities].

A study is presented of 89 patients with primary and recurrent erysipelas of the lower extremities. Ultrasound sonography, dopplerography and tetrapolar rheography were used in the examination. It was found that disorders of the peripheral circulation remain stable in the inter-recurrence period, are manifested by lymphovenous insufficiency, continuous state of pre-edema, trophic disorders of the lower extremities.

Adult↗
PubMed1990

[The level of IgM, IgG and IgA antibodies and total antibodies to the low-molecular, cell-wall protein of Streptococcus group A without type specificity in the serum of patients with a streptococcal infection].

The levels of IgM, IgG and IgA antibodies, as well as total antibodies, to group A streptococcal low-molecular cell-wall protein without type specificity were studied in the sera of patients with primary erysipelas, rheumatism in the active and inactive phases, seronegative rheumatoid arthritis, as well as in the sera of healthy donors. The average level of antibodies to low-molecular protein in the sera of all groups of patients was significantly higher than the sera of healthy donors. The analysis of the distribution of antibodies in accordance with their isotypes revealed the specific features of response, characteristic of each group of patients. For rheumatism patients, the positive correlation between response to low-molecular protein and response to group-specific polysaccharide A was established. This correlation was most pronounced in patients with rheumatism in the inactive phase.

Antibodies, Bacterial↗
PubMed1985

[Determination of antibodies to Streptococcus group A polysaccharide by an immunodiffusion method in human sera in various pathological processes of streptococcal etiology].

A method for the assay of antibodies to the specific antigenic determinant of group A streptococcal polysaccharide (A-polysaccharide) in human sera was developed. The sera were tested in the precipitation test in agar gel with different doses of A-polysaccharide. The presence of a high level of the above-mentioned antibodies is indicative of infection caused by group A streptococcus, but not streptococci of other groups or by the L-forms of streptococci. In 87.5% of patients with primary rheumatism a high level of antibodies to the specific antigenic determinant of A-polysaccharide was detected during the first day of the disease, which confirms most convincingly the etiological role of group A streptococcus in rheumatism. Considerable differences in the level of antibodies to A-polysaccharide in the active and non-active phases of rheumatism have been established, which makes it possible to use the presence of a high level of these antibodies as an indicator of the rheumatic process activity. A considerable percentage of sera with a high level of antibodies to A-polysaccharide was also detected in erysipelas and acute glomerulonephritis patients.

Antibodies, Bacterial↗
PubMed1989

[Detection of Erysipelothrix rhusiopathiae specific antibodies in the serum of experimentally-infected swine by ELISA and immunoblotting].

In an attempt to characterize the immuno response of the animal organism to experimental infection, ELISA and immunoblotting were used to test the antibody levels of erysipelas hyperimmune sera (HIS) which had been induced by Erysipelothrix rhusiopathiae. Also, 5 pigs were accidentally chosen to check on individual curves of antibody formation, following periodical inoculation up to HIS collection. All HIS verified and confirmed by the mouse protective test responded by high titres. Yet, the results so far obtained from HIS titration have failed to be conclusive as to valency. The animals selected for these experiments exhibited differentiated antibody levels during the phase of immunisation, although they were at one and the same level, when measured by the final titre, following last boostering. The desired rise in antibody levels was achieved only by the 4th to 9th boostering in almost all cases. Extinction values determined by ELISA were confirmed or supplemented by the results obtained from immunoblotting.

Animals↗
PubMed1989

[Conservative treatment of chronic lymphedema].

Decongestion of chronic lymphedema can be achieved by supportive bandages without elasticity, manual lymph drainage (especially in cases of secondary lymphedema after treatment of cancer), and remedial exercises performed while wearing bandages. Hygienic skin care is necessary to avoid attacks of recurrent erysipelas. In order to preserve the reduction of the edema once achieved, the patients have to wear elastic sleeves or stockings daily.

Bandages↗
PubMed1986

[Cutaneous manifestations of periodic disease].

The authors report the case of an 8 year-old girl admitted for an erysipelas-like rash of the lower limbs and an episode of Henoch-Schönlein purpura. These manifestations were subsequently attributed to familial mediterranean fever. This case report illustrates the polymorphism of cutaneous manifestations in this disease.

Child↗
PubMed1987

Early detection of streptococcal group antigens in skin samples by latex particle agglutination.

The streptococcal group antigens (A to G) were researched in skin biopsy specimens by a latex agglutination technique using commercial (Slidex Streptokit bio-Mérieux and Streptex Wellcome) and experimental reagents. Twenty-seven patients with obvious cutaneous infections (12 cases of erysipelas, nine cases of cellulitis, and six cases of necrotizing fasciitis) and 27 age- and sex-matched controls were studied. Our preliminary data demonstrated the possibility of an early diagnosis of streptococcal cutaneous infections involving the deep dermis and/or hypodermis. We used a latex agglutination technique that is quite specific and gives a better sensitivity (0.63) than either conventional bacteriologic cultures on needle aspiration or skin biopsy specimens.

Adult↗
PubMed1985

Old familiar faces: some aspects of the asylum era in Britain. Part 1.

Conditions which had an historical association with Asylums in the years 1850-1950, but which are no longer commonly seen in psychiatric practice, are reviewed. These include: Asylum pellagra, Erysipelas, Insane Ear and Fractured Ribs. The history of each condition and its manifestation is reviewed in the context of its relationship with mental illness and its treatment as seen by authorities writing when these conditions were prevalent. It is not clear why these conditions became common, why they had a particular association with Asylums, or why they have largely disappeared.

Ear Diseases↗
PubMed1979

[An unusual case of carpal tunnel syndrome].

A severe form of a carpal-tunnel-syndrome with motoric and sensoric deficits and trophic disturbances of the fingers II and III is presented, which reminds also of syringomyelia, erysipeloid or a chronic erysipelas.

Carpal Tunnel Syndrome↗
PubMed1983

Group A streptococcal meningitis.

A retrospective record study of six cases of meningitis caused by group A beta-hemolytic Streptococcus is presented. Associated findings included otitis media, pharyngitis, and erysipelas. All patients survived their infections despite major complications including seizures, shock, coma, renal failure, and hepatitis. Two patients had neurologic sequelae. Group A Streptococcus causes a severe form of bacterial meningitis in apparently healthy children.

Child↗
PubMed1983

[Streptococcus (S. pyogenes) group A septicemia. Analysis of 20 cases in adults].

From 1976 to 1981, 25 cases of S. pyogenes septicemia were diagnosed at the University Medical Center, Lausanne, Switzerland, in 5 children and 20 adults. The twenty adult patients are described. The age range was from 24 to 94 years. The portal of entry was the skin (erysipelas, skin ulcers, surgical wounds) in 12 cases, the respiratory tract (upper 3, lower 3) in 6 cases, and the vagina in 2 cases. All except 3 patients were acutely ill with high temperature (39 degrees C) and toxic appearance. None had an underlying malignancy. The clinical course was complicated in 5 patients, i.e. septic arthritis (2), pulmonary abscess (1), endocarditis (1) and acute rheumatic fever (1). After initiation of penicillin therapy, temperature and symptoms resolved only slowly (mean 11 days). Four patients died from infection. In 2 of them the antibiotic treatment had been delayed. When a patient exhibits clinical signs of septicemia and muco-cutaneous lesions suggestive of a portal of entry, S. pyogenes septicemia should be suspected. Complications are frequent and the prognosis remains poor despite early adequate antibiotic treatment.

Adult↗
PubMed1984

[Diagnostic difficulties in herpes zoster].

The authors have analysed the clinical and laboratory findings in 170 patients with herpes zoster (HZ). Of these, 21 patients (12.3%) had been erroneously diagnosed before the appearance of herpetic eruption as having other diseases (erysipelas, renal colic, acute pancreatitis, acute abdomen, and so forth). The authors point to the difficulties encountered in making the diagnosis at the initial disease period with emphasis on the great importance for early diagnosis of HZ of the analysis of the clinical findings, prodromal period and hemogram data.

Abdomen, Acute↗
PubMed1984

[Quantitative methods of assessing the severity of an epizootic situation].

n order to evaluate the epizootic status of a particular territory for a given moment or a period of time with regard to the infectious diseases one has adopted Tarshis ' formula. The present work deals with the comparative approbation of this formula, using a modified formula in which a parameter characterizing the intensity of the epizootic process was introduced. The epizootic situation and its severity was determined by the two formulas for each district of the country with regard to the following infectious diseases: gangrenous mastitis and listeriosis of sheep, swine erysipelas, and anthrax of all kinds of farm animals--all for the 1970-1981 period. A categorization of the districts is effected according to the values obtained. It was found that the modified formula is important for the objectivization of the severity of the epizootic status as it reflected also the territorial spread and intensity of the epizootic process.

Animals↗