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Gastrointestinal hemorrhage in end stage renal disease patients.

Over a six year span, 41 patients with end stage renal disease (ESRD) were treated for 53 episodes of upper and lower gastrointestinal (UGI & LGI) hemorrhage. Thirty-two patients (78%) were diagnosed as having UGI bleeding and nine patients as having LGI bleeding. Mucosal inflammation of the esophagus, stomach and duodenum were the predominant etiologies of UGI bleeding (64%). The predominant cause of LGI hemorrhage was diverticular disease (33%). Angiodysplasias were found in six patients (15%), four with UGI bleeding and two with LGI bleeding. In the UGI hemorrhage group 20% of the bleeding episodes were recurrent and 13% were from multiple sites. There were no recurrent bleeding episodes in the LGI hemorrhage group. We therefore conclude that UGI bleeding is much more common than LGI bleeding in ESRD patients, and that there is a significantly higher tendency for recurrent bleeding episodes and for multiple bleeding sites in the UGI hemorrhage patients. We also note a higher prevalence of angiodysplasias of the upper and lower gastrointestinal tract in ESRD patients.

Adult↗

[Lower gastrointestinal hemorrhage: etiologic assessment and surgical concept].

Due to its occurence in patients at higher ages with comorbidities, lower gastrointestinal bleeding remains a challenge in terms of diagnostic and therapeutic strategies. In this series (1994-1997, n = 40) the source of bleeding was in the upper gastrointestinal tract in 38% and in the lower gastrointestinal tract in 62%. The source of bleeding could be localized in 58%. Bleeding stopped spontaneously in 40% of all patients but 60% required intervention (54% radiologic or endoscopic intervention, 46% surgery). Segmental resection was the procedure most frequently employed (8/11 patients), 3 patients underwent a subtotal colectomy. In-hospital mortality and surgical morbidity were 0/11 each. Following a staged diagnostic approach and segmental surgical resection, lower gastrointestinal bleeding can be treated with a low morbidity, mortality and a low rebleeding rate.

Adult↗

[Tactics in gastrointestinal hemorrhage under conditions of medical aviation].

Doctors of the medical aviation service were consulted in 774 cases of gastrointestinal bleeding of various genesis in 1985-1989. Chronic gastroduodenal ulcer (peptic ulcer of the anastomosis among others) was the source of the bleeding in 473 (64.88%) patients. In the first period of observation (1985-1986) active surgical tactics was applied in 103 patients with chronic bleeding ulcer. Fifty-one patients (49.5%) underwent operation, with a fatal outcome in 12 cases (23.5%). Active individualized tactics was accepted in the second period (1987-1989). In a group of 370 patients 185 (50%) were operated on, 20 with fatal outcomes (10.8%). Active surgical tactics was individualized by strict comparison of the amount of blood loss and the degree of activity of the bleeding. Clinico-endoscopic and laboratory interpretation of the degree of activity of the bleeding is described and the expediency of indicating this criterion along with the amount of blood loss in establishing the diagnosis in a patient with bleeding from the ulcer is pointed out.

Adult↗

Upper gastrointestinal hemorrhage associated with pancreatitis.

In a two-year period from June 1981, two cases of acute upper gastrointestinal bleeding caused by pancreatitis were observed. In both cases the bleeding was caused by erosion of the gastric mucosa contiguous to, respectively, a pseudocyst and an abscess of the pancreas. Both patients were successfully treated with cystogastrostomy. Erosive bleeding from gastrointestinal mucosa adjoining pancreatic lesions may be a more common source of upper gastrointestinal bleeding than has hitherto been assumed.

Abscess↗

[Chronic pancreatitis and upper gastrointestinal hemorrhage].

A 46 year-old woman with a history of chronic pancreatitis, upper epigastric pain and upper gastrointestinal bleeding of obscure origin is presented. A haemoductal pancreatitis was the source of bleeding due to erosion of the splenic artery with bleeding into a pancreatic pseudocyst communicating with the pancreatic duct. This case was special, because there was no aneurysmal dilatation of the splenic artery. This rare entity must always be considered in the diagnosis of gastrointestinal haemorrhage of obscure origin. The appropriate investigation to confirm the diagnosis is visceral angiography, if necessary followed by CT-scan of the abdomen.

Chronic Disease↗